Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These com...Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These compounds have been instrumental in drug discovery,particularly for cancer and infectious diseases,as well as in other therapeutic areas such as cardiovascular diseases(e.g.,statins)and multiple sclerosis(e.g.,fingolimod).展开更多
Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.Americ...Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.America’s“natural gas independence”has reshaped the global natural gas market,creating a new pattern of“supply shifting westward and consumption shifting eastward”.展开更多
BACKGROUND Severe acute respiratory syndrome coronavirus 2 induced coronavirus disease 2019(COVID-19)has posed a great challenge to public health worldwide and also increased susceptibility to colorectal cancer(CRC).N...BACKGROUND Severe acute respiratory syndrome coronavirus 2 induced coronavirus disease 2019(COVID-19)has posed a great challenge to public health worldwide and also increased susceptibility to colorectal cancer(CRC).Natural killer(NK)cells serve as the first line of defense in the host’s innate immune system,performing natural killing functions and mediating cytotoxicity against tumors and viruses.Therefore,a better understanding of NK cell cytotoxicity may facilitate the development of treatment strategies for CRC-associated with COVID-19.AIM To investigate the cytotoxic killing function of peripheral NK cells in patients with CRC and severe COVID-19(CRC+patients).METHODS The percentages of circulating NK and NKT cells in CRC+and age-matched patients with CRC were analyzed using flow cytometry.NK cell cytotoxic activity(NKCA)and corresponding NK cytotoxic factor(NKCF)activity in peripheral blood mononuclear cells were evaluated using a Real-Time Cell Analyzer.RESULTS The numbers and percentage of peripheral NK and NKT cells in patients with CRC+were lower than those in patients with CRC.Additionally,compared to patients with CRC,those with CRC+had lower levels of NKCA and NKCF activity in lysed K562 cells.Positive correlations were observed between NKCA and NK cell numbers,NKCA and NK cell percentages,NKCF activity,and NK cell percentages in patients with CRC+.Furthermore,a negative correlation was observed between NKCA and the severity of COVID-19 in patients with CRC.The area under the receiver operating characteristic curve for NKCA was greater than those for the other indices.CONCLUSION CRC+is associated with lower levels of peripheral NK cells and impaired natural cytotoxicity,contributing to the immunopathogenesis of severe COVID-19 rather than immune control.展开更多
Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug...Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug discovery but also inspire innovative strategies in drug development.The biomimetic synthesis of natural products employs principles from biomimicry,applying inspiration from biogenetic processes to design synthetic strategies that mimic biosynthetic processes.Biomimetic synthesis is a highly efficient approach in synthetic chemistry,as it addresses critical challenges in the synthesis of structurally complex natural products with significant biological and medicinal importance.It has gained widespread attention from researchers in chemistry,biology,pharmacy,and related fields,underscoring its interdisciplinary impact.In this perspective,we present recent advances and challenges in the biomimetic synthesis of natural products,along with the significance and prospects of this field,highlighting the transformative potential of biomimetic synthesis strategies for both chemical and biosynthetic approaches to natural product synthesis in the pursuit of novel therapeutic agents.展开更多
This article revisits the concept of epistemological rupture by questioning the stark division between scientific and non-scientific thought. Drawing on the theory of representation, it contends that both forms of kno...This article revisits the concept of epistemological rupture by questioning the stark division between scientific and non-scientific thought. Drawing on the theory of representation, it contends that both forms of knowledge are socially constructed, moulded by communication, norms and group dynamics. Rather than labelling non-scientific thought as flawed or regressive, the discussion shows how decontextualization and recontextualization processes apply equally to everyday ‘natural' knowledge and formal science,exposing the social and historical contingencies shaping concepts. Consequently, rupture appears less a sudden break than a gradual threshold reached through dialectical transformations in cognition and society. Rather than conferring total superiority on science, ruptures highlight how certain discourses gain legitimacy while others become ‘non-knowledge'. The article concludes that science's dominance reflects broader power relationships and evolving modes of production and validation. By situating epistemological rupture within these processes, it illuminates how different knowledge forms coexist, evolve and sometimes conflict in stratified social fields—ultimately challenging a simplistic binary between scientific progress and supposedly primitive or natural thought. This viewpoint opens new possibilities for examining the shifting boundaries between rational explanations and the shared beliefs shaping collective reality and daily life.展开更多
First Published:2020 ISBN:9781421438740 Published by John Hopkins Press https://www.press.jhu.edu“The geological imagination of India,its landscapes,people,past and destiny,drive the narrative of this book”,Pratik C...First Published:2020 ISBN:9781421438740 Published by John Hopkins Press https://www.press.jhu.edu“The geological imagination of India,its landscapes,people,past and destiny,drive the narrative of this book”,Pratik Chakrabarti writes in his introduction to Inscriptions of Nature.His ambitious work examines the development of the natural and anthropological sciences on the Indian subcontinent since the early 19th century,and the shaping of knowledge about Indian nature through the exploration of its deep past:an exploration that dug not only into the depths of the earth,but also into ancient history,texts,myths,legends,folklore and the genealogies of local populations.This in-depth study not only combines the history of geology,paleontology,anthropology and ethnography,it also finely analyzes the interactions between the theoretical framework of scientific knowledge imported from Europe and local history,mythologies and indigenous beliefs.展开更多
The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 357.68 in the 2nd quarter of 2025,up 3.1% from the 1st quarter of 2025,a stably prosper...The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 357.68 in the 2nd quarter of 2025,up 3.1% from the 1st quarter of 2025,a stably prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas production companies was 542.01 in the 2nd quarter of 2025,up 4.8% from the 1st quarter of 2025,an increasingly prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas sales companies was 209.06 in the 2nd quarter of 2025,up 0.4% from the 1st quarter of 2025,an increasing prosperity in the short term and a prosperous state in the medium to long term;the prosperity trend index of the natural gas industry in the coming year for the 2nd quarter of 2025 was 765.70,up 4.1% from the 1st quarter of 2025,a very prosperous state,indicating that natural gas industry experts are optimistic about the natural gas industry’s prosperity trend in the coming year.See Fig.1 and Table 1 for details.展开更多
The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 346.98 in the 1st quarter of 2025,up 2.8%from the 4th quarter of 2024,a stably prospero...The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 346.98 in the 1st quarter of 2025,up 2.8%from the 4th quarter of 2024,a stably prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas production companies was 517.14 in the 1st quarter of 2025,up 4.5%from the 4th quarter of 2024,an increasingly prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas sales companies was 208.26 in the 1st quarter of 2025,down 0.9%from the 4th quarter of 2024.The gas sales company has experienced a decline in prosperity in short term,yet this does not alter its long-term upward trend.In the medium to long term,it remains in a highly prosperous state.;the prosperity trend index of the natural gas industry in the coming year for the 1st quarter of 2025 was 735.21,up 3.9%from the 4th quarter of 2024,a very prosperous state,indicating that natural gas industry experts are optimistic about the natural gas industry’s prosperity trend in the coming year.See Fig.1 and Table 1 for details.展开更多
On 13 December 2024,liquefied natural gas(LNG)company Venture Global LNG(Arlington,VA,USA)commenced commercial production of the super-chilled fuel at its partially completed Plaquemines LNG export terminal in Louisia...On 13 December 2024,liquefied natural gas(LNG)company Venture Global LNG(Arlington,VA,USA)commenced commercial production of the super-chilled fuel at its partially completed Plaquemines LNG export terminal in Louisiana(Fig.1)[1].In terms of dollars invested,the 21 billion USD plant is the fourth largest infrastructure project in the world[2].Venture Global initially expected the terminal to produce and ship 20 million tonnes of LNG annually[3].An 18 billion USD expansion of the terminal approved in February 2025 will bring its maximum annual produc-tion capacity to 45 million tonnes[4].When fully operational in 2027,the facility,located in Plaquemines Parish on the Mississippi River about 32 km south of New Orleans,will be among the largest in the world,further contributing to the US position as the world’s biggest LNG exporter[1].展开更多
Accurate identification of natural gas origin is fundamental to the theoretical research on natural gas geosciences and the exploration deployment and resource potential assessment of oil and gas.Since the 1970s,Acade...Accurate identification of natural gas origin is fundamental to the theoretical research on natural gas geosciences and the exploration deployment and resource potential assessment of oil and gas.Since the 1970s,Academician Dai Jinxing has developed a comprehensive system for natural gas origin determination,grounded in geochemical theory and practice,and based on the integrated analysis of stable isotopic compositions,molecular composition,light hydrocarbon fingerprints,and geological context.This paper systematically reviews the core framework established by him and his team according to related references and application results,focusing on the conceptual design and technical pathways of key diagnostic diagrams such asδ^(13)C_(1)-C_(1)/(C_(2)+C_(3)),δ^(13)C_(1)-δ^(13)C_(2)-δ^(13)C_(3),δ^(13)CCO_(2)versus CO_(2)content,and the C7light hydrocarbon ternary plot.We evaluate the applicability and innovation of these tools in distinguishing between oil-type gas,coal-derived gas,microbial gas,and abiogenic gas,as well as in identifying mixed-source gases and multi-stage charging systems.The findings suggest that this identification system has significantly advanced natural gas geochemical interpretation in China,shifting from single-indicator analyses to multi-parameter integration and from qualitative assessments to systematic graphical identification,and has also exerted considerable influence on international research in natural gas geochemistry.The structured overview of the development trajectory of natural gas origin discrimination methodologies provides a technical support for natural gas geological theory and practice and offers a scientific foundation for the academic evaluation and application of related achievements.展开更多
1.Introduction With the increasing demand for petroleum and natural gas resources,along with technological advancements in exploration and production,the primary frontier of oil and gas resources has shifted from conv...1.Introduction With the increasing demand for petroleum and natural gas resources,along with technological advancements in exploration and production,the primary frontier of oil and gas resources has shifted from conventional oil and gas development to the domains of“Two Deeps,One Unconventional,One Mature,”which include deep onshore,deepwater,unconventional resources,and mature oilfields[1].展开更多
Highlights●Natural variations in the SGT3 promoter TATA box repeats directly modulate gene expression and SGAs content in tubers,providing a novel molecular marker for low-steroidal glycoalkaloids(SGAs)breeding.●The...Highlights●Natural variations in the SGT3 promoter TATA box repeats directly modulate gene expression and SGAs content in tubers,providing a novel molecular marker for low-steroidal glycoalkaloids(SGAs)breeding.●The SGT3 promoter haplotype with(TA)10exhibits signifcantly higher transcriptional activity,correlating with high SGAs content,while the(TA)13haplotype is linked to low SGAs in natural germplasms.展开更多
Clarifying the system structure of various influencing factors is a crucial prerequisite for identifying the key action point to address the“Energy Trilemma”in China’s natural gas industry.Based on the three-dimens...Clarifying the system structure of various influencing factors is a crucial prerequisite for identifying the key action point to address the“Energy Trilemma”in China’s natural gas industry.Based on the three-dimensional system of“safety and stability-economic feasibility-low-carbon and environmental protection,”an influencing factor system for the“Energy Trilemma”in the natural gas industry is constructed.展开更多
CHINA Gaoligongshan National Natural Reserve Rising to over 4,000 metres above sea level in western Yunnan Province,Gaoligong Mountain forms part of the southern Hengduan Mountain Range and is renowned for its rich bi...CHINA Gaoligongshan National Natural Reserve Rising to over 4,000 metres above sea level in western Yunnan Province,Gaoligong Mountain forms part of the southern Hengduan Mountain Range and is renowned for its rich biodiversity and vibrant cultural landscape.Encompassing a vast protected area across the Tengchong and Baoshan regions,the Gaoligongshan National Natural Reserve is a secluded ecological treasure trove.In April 2000,the reserve joined the UNESCO World Network of Biosphere Reserves.展开更多
1 Introduction.Chinese Medicine and Natural Products(CMNP)a quarterly,open-access publication that is funded fficially by 2017 Project for Enhancing International Impact of China STM Jounals.
Natural gas hydrate(NGH),as a widely recognized clean energy,has shown a significant resource potential.However,due to the lack of a unified evaluation methodology and the difficult determination of key parameters,the...Natural gas hydrate(NGH),as a widely recognized clean energy,has shown a significant resource potential.However,due to the lack of a unified evaluation methodology and the difficult determination of key parameters,the evaluation results of global NGH resource are greatly different.This paper establishes a quantitative relationship between NGH resource potential and conventional oil and gas resource and a NGH resource evaluation model based on the whole petroleum system(WPS)and through the analysis of dynamic field controlling hydrocarbon accumulation.The global NGH initially in-place and recoverable resources are inverted through the Monte Carlo simulation,and verified by using the volume analogy method based on drilling results and the trend analysis method of previous evaluation results.The proposed evaluation model considers two genetic mechanisms of natural gas(biological degradation and thermal degradation),surface volume conversion factor difference between conventional natural gas and NGH,and the impacts of differences in favorable distribution area and thickness and in other aspects on the results of NGH resource evaluation.The study shows that the global NGH initially in-place and recoverable resources are 99×10^(12) m^(3) and 30×10^(12) m3,with averages of 214×10^(12) m^(3) and 68×10^(12) m^(3),respectively,less than 5% of the total conventional oil and gas resources,and they can be used as a supplement for the future energy of the world.The proposed NGH resource evaluation model creates a new option of evaluation method and technology,and generates reliable data of NGH resource according to the reliability comprehensive analysis and test,providing a parameter basis for subsequent NGH exploration and development.展开更多
1 IntroductionChinese Medicine and Natural Products(CMNP)a quar-terly,open-access publication that is funded officially by 2017 Project for Enhancing International Impact of China STM Journals.CMNP is devoted to publi...1 IntroductionChinese Medicine and Natural Products(CMNP)a quar-terly,open-access publication that is funded officially by 2017 Project for Enhancing International Impact of China STM Journals.CMNP is devoted to publishing the theoretical and clinical research achievements in the field of Chinese medicine so as to promote the academic exchange of Chinese medicine.展开更多
Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research fun...Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.展开更多
1 Introduction Chinese Medicine and Natural Products(CMNP)a quarterly,open-access publication that is funded officially by 2017 Project for Enhancing International Impact of China STM Journals.
We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accom...We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accommodative monetary policy to mitigate the impact of the China-U.S.trade friction.Will this further easing of the monetary environment lead to an increase in natural gas prices?展开更多
文摘Natural products(NPs)derived from plants,microbes,and marine organisms have historically been a cornerstone of pharmacotherapy,accounting for approximately 35%of FDA-approved small-molecule drugs since 19811.These compounds have been instrumental in drug discovery,particularly for cancer and infectious diseases,as well as in other therapeutic areas such as cardiovascular diseases(e.g.,statins)and multiple sclerosis(e.g.,fingolimod).
文摘Since 2011,America has maintained its position as the world’s largest natural gas producer.Since 2017,America has consistently experienced a surplus in natural gas supply,becoming a net exporter of natural gas.America’s“natural gas independence”has reshaped the global natural gas market,creating a new pattern of“supply shifting westward and consumption shifting eastward”.
文摘BACKGROUND Severe acute respiratory syndrome coronavirus 2 induced coronavirus disease 2019(COVID-19)has posed a great challenge to public health worldwide and also increased susceptibility to colorectal cancer(CRC).Natural killer(NK)cells serve as the first line of defense in the host’s innate immune system,performing natural killing functions and mediating cytotoxicity against tumors and viruses.Therefore,a better understanding of NK cell cytotoxicity may facilitate the development of treatment strategies for CRC-associated with COVID-19.AIM To investigate the cytotoxic killing function of peripheral NK cells in patients with CRC and severe COVID-19(CRC+patients).METHODS The percentages of circulating NK and NKT cells in CRC+and age-matched patients with CRC were analyzed using flow cytometry.NK cell cytotoxic activity(NKCA)and corresponding NK cytotoxic factor(NKCF)activity in peripheral blood mononuclear cells were evaluated using a Real-Time Cell Analyzer.RESULTS The numbers and percentage of peripheral NK and NKT cells in patients with CRC+were lower than those in patients with CRC.Additionally,compared to patients with CRC,those with CRC+had lower levels of NKCA and NKCF activity in lysed K562 cells.Positive correlations were observed between NKCA and NK cell numbers,NKCA and NK cell percentages,NKCF activity,and NK cell percentages in patients with CRC+.Furthermore,a negative correlation was observed between NKCA and the severity of COVID-19 in patients with CRC.The area under the receiver operating characteristic curve for NKCA was greater than those for the other indices.CONCLUSION CRC+is associated with lower levels of peripheral NK cells and impaired natural cytotoxicity,contributing to the immunopathogenesis of severe COVID-19 rather than immune control.
基金financially supported by the National Key Research and Development Program of China(2023YFC3503902)the National Natural Science Foundation of China(82430108,82293681(82293680),and 82321004)+2 种基金the Guangdong Basic and Applied Basic Research Foundation(2022B1515120015 and 2024A1515030103)the Guangdong Major Project of Basic and Applied Basic Research(2023B0303000026)the Science and Technology Projects in Guangzhou(202102070001)。
文摘Natural products,with their remarkable structural and biological diversity,have historically served as a vital bridge between chemistry,the life sciences,and medicine.They not only provide essential scaffolds for drug discovery but also inspire innovative strategies in drug development.The biomimetic synthesis of natural products employs principles from biomimicry,applying inspiration from biogenetic processes to design synthetic strategies that mimic biosynthetic processes.Biomimetic synthesis is a highly efficient approach in synthetic chemistry,as it addresses critical challenges in the synthesis of structurally complex natural products with significant biological and medicinal importance.It has gained widespread attention from researchers in chemistry,biology,pharmacy,and related fields,underscoring its interdisciplinary impact.In this perspective,we present recent advances and challenges in the biomimetic synthesis of natural products,along with the significance and prospects of this field,highlighting the transformative potential of biomimetic synthesis strategies for both chemical and biosynthetic approaches to natural product synthesis in the pursuit of novel therapeutic agents.
文摘This article revisits the concept of epistemological rupture by questioning the stark division between scientific and non-scientific thought. Drawing on the theory of representation, it contends that both forms of knowledge are socially constructed, moulded by communication, norms and group dynamics. Rather than labelling non-scientific thought as flawed or regressive, the discussion shows how decontextualization and recontextualization processes apply equally to everyday ‘natural' knowledge and formal science,exposing the social and historical contingencies shaping concepts. Consequently, rupture appears less a sudden break than a gradual threshold reached through dialectical transformations in cognition and society. Rather than conferring total superiority on science, ruptures highlight how certain discourses gain legitimacy while others become ‘non-knowledge'. The article concludes that science's dominance reflects broader power relationships and evolving modes of production and validation. By situating epistemological rupture within these processes, it illuminates how different knowledge forms coexist, evolve and sometimes conflict in stratified social fields—ultimately challenging a simplistic binary between scientific progress and supposedly primitive or natural thought. This viewpoint opens new possibilities for examining the shifting boundaries between rational explanations and the shared beliefs shaping collective reality and daily life.
文摘First Published:2020 ISBN:9781421438740 Published by John Hopkins Press https://www.press.jhu.edu“The geological imagination of India,its landscapes,people,past and destiny,drive the narrative of this book”,Pratik Chakrabarti writes in his introduction to Inscriptions of Nature.His ambitious work examines the development of the natural and anthropological sciences on the Indian subcontinent since the early 19th century,and the shaping of knowledge about Indian nature through the exploration of its deep past:an exploration that dug not only into the depths of the earth,but also into ancient history,texts,myths,legends,folklore and the genealogies of local populations.This in-depth study not only combines the history of geology,paleontology,anthropology and ethnography,it also finely analyzes the interactions between the theoretical framework of scientific knowledge imported from Europe and local history,mythologies and indigenous beliefs.
文摘The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 357.68 in the 2nd quarter of 2025,up 3.1% from the 1st quarter of 2025,a stably prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas production companies was 542.01 in the 2nd quarter of 2025,up 4.8% from the 1st quarter of 2025,an increasingly prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas sales companies was 209.06 in the 2nd quarter of 2025,up 0.4% from the 1st quarter of 2025,an increasing prosperity in the short term and a prosperous state in the medium to long term;the prosperity trend index of the natural gas industry in the coming year for the 2nd quarter of 2025 was 765.70,up 4.1% from the 1st quarter of 2025,a very prosperous state,indicating that natural gas industry experts are optimistic about the natural gas industry’s prosperity trend in the coming year.See Fig.1 and Table 1 for details.
文摘The statistics of the China natural gas industry prosperity index showed that the China natural gas industry prosperity index was 346.98 in the 1st quarter of 2025,up 2.8%from the 4th quarter of 2024,a stably prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas production companies was 517.14 in the 1st quarter of 2025,up 4.5%from the 4th quarter of 2024,an increasingly prosperous state in the short term and a very prosperous state in the medium to long term;the prosperity index of natural gas sales companies was 208.26 in the 1st quarter of 2025,down 0.9%from the 4th quarter of 2024.The gas sales company has experienced a decline in prosperity in short term,yet this does not alter its long-term upward trend.In the medium to long term,it remains in a highly prosperous state.;the prosperity trend index of the natural gas industry in the coming year for the 1st quarter of 2025 was 735.21,up 3.9%from the 4th quarter of 2024,a very prosperous state,indicating that natural gas industry experts are optimistic about the natural gas industry’s prosperity trend in the coming year.See Fig.1 and Table 1 for details.
文摘On 13 December 2024,liquefied natural gas(LNG)company Venture Global LNG(Arlington,VA,USA)commenced commercial production of the super-chilled fuel at its partially completed Plaquemines LNG export terminal in Louisiana(Fig.1)[1].In terms of dollars invested,the 21 billion USD plant is the fourth largest infrastructure project in the world[2].Venture Global initially expected the terminal to produce and ship 20 million tonnes of LNG annually[3].An 18 billion USD expansion of the terminal approved in February 2025 will bring its maximum annual produc-tion capacity to 45 million tonnes[4].When fully operational in 2027,the facility,located in Plaquemines Parish on the Mississippi River about 32 km south of New Orleans,will be among the largest in the world,further contributing to the US position as the world’s biggest LNG exporter[1].
基金Supported by the“14th Five-Year Plan”Prospective and Basic Research Project of CNP)(2021DJ0502)Open Project of Key Laboratory of Shale Gas Resource Exploration(Chongqing Institute of Geology and Mineral Resources),Ministry of Natural Resources(KLSGE-2023)National Natural Science Foundation of China(42172149,U2244209)。
文摘Accurate identification of natural gas origin is fundamental to the theoretical research on natural gas geosciences and the exploration deployment and resource potential assessment of oil and gas.Since the 1970s,Academician Dai Jinxing has developed a comprehensive system for natural gas origin determination,grounded in geochemical theory and practice,and based on the integrated analysis of stable isotopic compositions,molecular composition,light hydrocarbon fingerprints,and geological context.This paper systematically reviews the core framework established by him and his team according to related references and application results,focusing on the conceptual design and technical pathways of key diagnostic diagrams such asδ^(13)C_(1)-C_(1)/(C_(2)+C_(3)),δ^(13)C_(1)-δ^(13)C_(2)-δ^(13)C_(3),δ^(13)CCO_(2)versus CO_(2)content,and the C7light hydrocarbon ternary plot.We evaluate the applicability and innovation of these tools in distinguishing between oil-type gas,coal-derived gas,microbial gas,and abiogenic gas,as well as in identifying mixed-source gases and multi-stage charging systems.The findings suggest that this identification system has significantly advanced natural gas geochemical interpretation in China,shifting from single-indicator analyses to multi-parameter integration and from qualitative assessments to systematic graphical identification,and has also exerted considerable influence on international research in natural gas geochemistry.The structured overview of the development trajectory of natural gas origin discrimination methodologies provides a technical support for natural gas geological theory and practice and offers a scientific foundation for the academic evaluation and application of related achievements.
基金the Science Foundation of China University of Petroleum,Beijing(Grant No.2462024YJRC021)the National Natural Science Foundation of China(Grant No.U24B2031 and 52104013).
文摘1.Introduction With the increasing demand for petroleum and natural gas resources,along with technological advancements in exploration and production,the primary frontier of oil and gas resources has shifted from conventional oil and gas development to the domains of“Two Deeps,One Unconventional,One Mature,”which include deep onshore,deepwater,unconventional resources,and mature oilfields[1].
基金financially supported by the Guangdong Major Project of Basic and Applied Basic Research,China(2021B0301030004)the National Natural Science Foundation of China(32360757,U2202206 and 32361143517)the Yunnan Fundamental Research Projects,China(202201AT070037,202501AS070012)。
文摘Highlights●Natural variations in the SGT3 promoter TATA box repeats directly modulate gene expression and SGAs content in tubers,providing a novel molecular marker for low-steroidal glycoalkaloids(SGAs)breeding.●The SGT3 promoter haplotype with(TA)10exhibits signifcantly higher transcriptional activity,correlating with high SGAs content,while the(TA)13haplotype is linked to low SGAs in natural germplasms.
基金Western Project of the National Social Science Fund of China (22XGL019)Major Project of the National Social Science Fund of China (22&ZD105)+1 种基金Special Academic Research Grant at the Key Research Base of Philosophy and Social Sciences in Sichuan Province (SC24E091)Chengdu Philosophy and Social Science Planning Project 2024 (2024BS072)。
文摘Clarifying the system structure of various influencing factors is a crucial prerequisite for identifying the key action point to address the“Energy Trilemma”in China’s natural gas industry.Based on the three-dimensional system of“safety and stability-economic feasibility-low-carbon and environmental protection,”an influencing factor system for the“Energy Trilemma”in the natural gas industry is constructed.
文摘CHINA Gaoligongshan National Natural Reserve Rising to over 4,000 metres above sea level in western Yunnan Province,Gaoligong Mountain forms part of the southern Hengduan Mountain Range and is renowned for its rich biodiversity and vibrant cultural landscape.Encompassing a vast protected area across the Tengchong and Baoshan regions,the Gaoligongshan National Natural Reserve is a secluded ecological treasure trove.In April 2000,the reserve joined the UNESCO World Network of Biosphere Reserves.
文摘1 Introduction.Chinese Medicine and Natural Products(CMNP)a quarterly,open-access publication that is funded fficially by 2017 Project for Enhancing International Impact of China STM Jounals.
基金Supported by the Major Consultation Project of the Chinese Academy of Sciences(2019-ZW11-Z-035)Technology Development Project of PetroChina Research Institute of Petroleum Exploration&Development(2021DJ0101)。
文摘Natural gas hydrate(NGH),as a widely recognized clean energy,has shown a significant resource potential.However,due to the lack of a unified evaluation methodology and the difficult determination of key parameters,the evaluation results of global NGH resource are greatly different.This paper establishes a quantitative relationship between NGH resource potential and conventional oil and gas resource and a NGH resource evaluation model based on the whole petroleum system(WPS)and through the analysis of dynamic field controlling hydrocarbon accumulation.The global NGH initially in-place and recoverable resources are inverted through the Monte Carlo simulation,and verified by using the volume analogy method based on drilling results and the trend analysis method of previous evaluation results.The proposed evaluation model considers two genetic mechanisms of natural gas(biological degradation and thermal degradation),surface volume conversion factor difference between conventional natural gas and NGH,and the impacts of differences in favorable distribution area and thickness and in other aspects on the results of NGH resource evaluation.The study shows that the global NGH initially in-place and recoverable resources are 99×10^(12) m^(3) and 30×10^(12) m3,with averages of 214×10^(12) m^(3) and 68×10^(12) m^(3),respectively,less than 5% of the total conventional oil and gas resources,and they can be used as a supplement for the future energy of the world.The proposed NGH resource evaluation model creates a new option of evaluation method and technology,and generates reliable data of NGH resource according to the reliability comprehensive analysis and test,providing a parameter basis for subsequent NGH exploration and development.
文摘1 IntroductionChinese Medicine and Natural Products(CMNP)a quar-terly,open-access publication that is funded officially by 2017 Project for Enhancing International Impact of China STM Journals.CMNP is devoted to publishing the theoretical and clinical research achievements in the field of Chinese medicine so as to promote the academic exchange of Chinese medicine.
文摘Periodontitis has emerged as one of the most critical oral diseases, and research on this condition holds great importance for the advancement of stomatology. As the most authoritative national scientific research funding institution in China, the National Natural Science Foundation of China (NSFC) has played a pivotal role in driving the progress of periodontal science by supporting research on periodontitis. This article provides a comprehensive review of the research and development progress related to periodontitis in China from 2014 to 2023, highlighting the significant contributions of the NSFC to this field. We have summarized the detailed funding information from the NSFC, including the number of applicant codes, funded programs and the distribution of funded scholars. These data illustrate the efforts of the NSFC in cultivating young scientists and building research groups to address key challenges in national scientific research. This study offers an overview of the current hot topics, recent breakthroughs and future research prospects related to periodontitis in China.
文摘1 Introduction Chinese Medicine and Natural Products(CMNP)a quarterly,open-access publication that is funded officially by 2017 Project for Enhancing International Impact of China STM Journals.
文摘We often hear statements like“the market raises expectations for central bank interest rate cuts,resulting in higher commodity prices”.Given the current situation,the People’s Bank of China might adopt a more accommodative monetary policy to mitigate the impact of the China-U.S.trade friction.Will this further easing of the monetary environment lead to an increase in natural gas prices?
