Introduction: Our aim was to identify the risk factors of clinical birth asphyxia and subsequent newborn death in the presence of nuchal cord in a sub-Saharan Africa setting. Methodology: It was a six-months’ case-co...Introduction: Our aim was to identify the risk factors of clinical birth asphyxia and subsequent newborn death in the presence of nuchal cord in a sub-Saharan Africa setting. Methodology: It was a six-months’ case-control study involving 117 parturients whose babies presented with a nuchal cord at delivery. The study was carried out at the Yaoundé Gyneco-Obstetric and Pediatric Hospital, Cameroon, from January 1st to June 30th 2013. Results: The risk factors of clinical birth asphyxia identified were: first delivery, absence of obstetrical ultrasound during pregnancy, nuchal cord with more than one loop, duration of second stage of labor more than 30 minutes during vaginal delivery. The risk factors for newborn death from clinical birth asphyxia in the presence of nuchal cord were: maternal age Conclusion: We recommend a systematic obstetrical ultrasound before labor, so as to detect the presence of a nuchal cord, its tightness and the number of loops. Also, cesarean section should be considered when a nuchal cord is associated with first delivery, tightness or multiple looping.展开更多
Objective: The present study was aimed at evaluating the outcome of pregnancies with a nuchal cord. Methods: A retrospective population-based study of all deliveries during the years 2011-2020 in Philippe Maguilen SEN...Objective: The present study was aimed at evaluating the outcome of pregnancies with a nuchal cord. Methods: A retrospective population-based study of all deliveries during the years 2011-2020 in Philippe Maguilen SENGHOR Center was conducted. Perinatal outcome of patients with and without nuchal cord was compared. Results: Among 44,958 deliveries during the study period, 1.8% had a nuchal cord, documented at birth (n = 807). Higher rates of labor induction (9.1% vs. 3.2%;p 0.001) and non-reassuring fetal heart rate patterns (RR = 2.366;CI: 1.631 - 3.432) were noted among pregnancies with nuchal cord as compared with the control group. The cesarean delivery rate was significantly higher among pregnancies with a nuchal cord (39.5% vs. 21.8%;RR = 2333;CI: 2.023 - 2.692). Although 5 min Apgar scores lower than 7 were more common in pregnancies with a nuchal cord (7.8% vs. 3.8%;RR = 2.117;CI: 1.629 - 3.363). There was no statistical significance between the two groups for the perinatal mortality. Conclusion: Nuchal cord is associated with prolonged labor and adverse perinatal outcome.展开更多
Objective: to analyze the value of transparent layer thickness ultrasound combined with four-dimensional color Doppler ultrasound of fetal neck in second trimester pregnancy in the diagnosis of fetal malformation. Met...Objective: to analyze the value of transparent layer thickness ultrasound combined with four-dimensional color Doppler ultrasound of fetal neck in second trimester pregnancy in the diagnosis of fetal malformation. Methods: 48 pregnant women who entered the gynecology department of our hospital from May 2019 to February 2020 for prenatal examination were selected for the experiment. The thickness of nuchal translucency of fetus was detected by ultrasound from 11 weeks to 14 weeks gestational age. Four-dimensional color Doppler ultrasonography was performed at 20 to 25 weeks of gestation. The diagnostic results were analyzed and the diagnostic sensitivity, specificity and accuracy were compared. Results: the results showed that the sensitivity, specificity and accuracy of ultrasonic examination of nuchal translucency thickness were 45.45%, 97.29% and 89.58%, respectively. The sensitivity, specificity and accuracy rate of four-dimensional color Doppler ultrasound in the second trimester of pregnancy were 90.90%, 100.00% and 97.91%. The detection rates of combined detection, nuchal translucency thickness ultrasound and four-dimensional ultrasound in the second trimester of pregnancy were different (P<0.05). Conclusion: the ultrasonic detection combined with four-dimensional color Doppler ultrasound of fetal neck translucency thickness in second trimester pregnancy has high accuracy in detecting fetal abnormalities and can be popularized.展开更多
项韧带骨化(Ossification of the Nuchal Ligament,ONL)指项韧带软组织区发生致密钙化或骨化,常由项韧带组织损伤与退变引起,破坏颈椎力学平衡引起颈部不适。ONL和术前颈椎不稳、颈椎病的发生之间存在相关性。ONL的发生发展与多种分子...项韧带骨化(Ossification of the Nuchal Ligament,ONL)指项韧带软组织区发生致密钙化或骨化,常由项韧带组织损伤与退变引起,破坏颈椎力学平衡引起颈部不适。ONL和术前颈椎不稳、颈椎病的发生之间存在相关性。ONL的发生发展与多种分子和环境因素相关,但ONL在不同阶段的病理生理发展的认识还不清楚。ONL是异位骨化类型之一,目前异位骨化已经发现多种致病基因,外在致病因素也被证实在异位骨化中起重要作用,这些研究有助于对ONL可能的病理生理机制进行剖析。因此,本文分析ONL的流行病学及病因学,解剖及生物力学,临床发展史、分型及临床意义,病理生理及基因调控机制、外在致病因素的相关文章,为伴有ONL的退变性颈脊髓病患者单开门术后的颈椎稳定性研究和ONL的分子机制研究提供建议。展开更多
文摘Introduction: Our aim was to identify the risk factors of clinical birth asphyxia and subsequent newborn death in the presence of nuchal cord in a sub-Saharan Africa setting. Methodology: It was a six-months’ case-control study involving 117 parturients whose babies presented with a nuchal cord at delivery. The study was carried out at the Yaoundé Gyneco-Obstetric and Pediatric Hospital, Cameroon, from January 1st to June 30th 2013. Results: The risk factors of clinical birth asphyxia identified were: first delivery, absence of obstetrical ultrasound during pregnancy, nuchal cord with more than one loop, duration of second stage of labor more than 30 minutes during vaginal delivery. The risk factors for newborn death from clinical birth asphyxia in the presence of nuchal cord were: maternal age Conclusion: We recommend a systematic obstetrical ultrasound before labor, so as to detect the presence of a nuchal cord, its tightness and the number of loops. Also, cesarean section should be considered when a nuchal cord is associated with first delivery, tightness or multiple looping.
文摘Objective: The present study was aimed at evaluating the outcome of pregnancies with a nuchal cord. Methods: A retrospective population-based study of all deliveries during the years 2011-2020 in Philippe Maguilen SENGHOR Center was conducted. Perinatal outcome of patients with and without nuchal cord was compared. Results: Among 44,958 deliveries during the study period, 1.8% had a nuchal cord, documented at birth (n = 807). Higher rates of labor induction (9.1% vs. 3.2%;p 0.001) and non-reassuring fetal heart rate patterns (RR = 2.366;CI: 1.631 - 3.432) were noted among pregnancies with nuchal cord as compared with the control group. The cesarean delivery rate was significantly higher among pregnancies with a nuchal cord (39.5% vs. 21.8%;RR = 2333;CI: 2.023 - 2.692). Although 5 min Apgar scores lower than 7 were more common in pregnancies with a nuchal cord (7.8% vs. 3.8%;RR = 2.117;CI: 1.629 - 3.363). There was no statistical significance between the two groups for the perinatal mortality. Conclusion: Nuchal cord is associated with prolonged labor and adverse perinatal outcome.
文摘Objective: to analyze the value of transparent layer thickness ultrasound combined with four-dimensional color Doppler ultrasound of fetal neck in second trimester pregnancy in the diagnosis of fetal malformation. Methods: 48 pregnant women who entered the gynecology department of our hospital from May 2019 to February 2020 for prenatal examination were selected for the experiment. The thickness of nuchal translucency of fetus was detected by ultrasound from 11 weeks to 14 weeks gestational age. Four-dimensional color Doppler ultrasonography was performed at 20 to 25 weeks of gestation. The diagnostic results were analyzed and the diagnostic sensitivity, specificity and accuracy were compared. Results: the results showed that the sensitivity, specificity and accuracy of ultrasonic examination of nuchal translucency thickness were 45.45%, 97.29% and 89.58%, respectively. The sensitivity, specificity and accuracy rate of four-dimensional color Doppler ultrasound in the second trimester of pregnancy were 90.90%, 100.00% and 97.91%. The detection rates of combined detection, nuchal translucency thickness ultrasound and four-dimensional ultrasound in the second trimester of pregnancy were different (P<0.05). Conclusion: the ultrasonic detection combined with four-dimensional color Doppler ultrasound of fetal neck translucency thickness in second trimester pregnancy has high accuracy in detecting fetal abnormalities and can be popularized.
文摘项韧带骨化(Ossification of the Nuchal Ligament,ONL)指项韧带软组织区发生致密钙化或骨化,常由项韧带组织损伤与退变引起,破坏颈椎力学平衡引起颈部不适。ONL和术前颈椎不稳、颈椎病的发生之间存在相关性。ONL的发生发展与多种分子和环境因素相关,但ONL在不同阶段的病理生理发展的认识还不清楚。ONL是异位骨化类型之一,目前异位骨化已经发现多种致病基因,外在致病因素也被证实在异位骨化中起重要作用,这些研究有助于对ONL可能的病理生理机制进行剖析。因此,本文分析ONL的流行病学及病因学,解剖及生物力学,临床发展史、分型及临床意义,病理生理及基因调控机制、外在致病因素的相关文章,为伴有ONL的退变性颈脊髓病患者单开门术后的颈椎稳定性研究和ONL的分子机制研究提供建议。
