有许多软件可以帮助分子生物学工作者解决一些他们日常实验室工作中遇到的问题。Vector NTI Su ite是一种高度集成、功能齐全的分子生物学应用软件,它可以对核酸、蛋白质等分子进行大量的操作和分析,以及建立和管理生物数据库。重点对Ve...有许多软件可以帮助分子生物学工作者解决一些他们日常实验室工作中遇到的问题。Vector NTI Su ite是一种高度集成、功能齐全的分子生物学应用软件,它可以对核酸、蛋白质等分子进行大量的操作和分析,以及建立和管理生物数据库。重点对Vector NTI Su ite软件的概况、应用现状及其在分子生物学领域的应用进行综述与探讨。展开更多
One of major difficulties in the implementation of meshfree methods using the mov- ing least square （MLS） approximation, such as element-free Galerkin method （EFG）, is the im- position of essential boundary condit...One of major difficulties in the implementation of meshfree methods using the mov- ing least square （MLS） approximation, such as element-free Galerkin method （EFG）, is the im- position of essential boundary conditions as the approximations do not pass through the nodal parameter values. Another class of meshfree methods based on the radial basis point interpola- tion can satisfy the essential boundary conditions exactly since its approximation function passes through each node in an influence domain and thus its shape functions possess the properties of delta function. In this paper, a coupled element-free Galerkin（EFG）-radial point interpola- tion method （RPIM） is proposed to enhance their advantages and avoid their disadvantages. Discretized equations of equilibrium are obtained in the RPIM region and the EFG region, respectively. Then a collocation approach is introduced to couple the RPIM and the EFG method. This method satisfies the linear consistency exactly and can maintain the stiffness matrix symmetric. Numerical tests show that this method gives reasonably accurate results consistent with the theory.展开更多
文摘有许多软件可以帮助分子生物学工作者解决一些他们日常实验室工作中遇到的问题。Vector NTI Su ite是一种高度集成、功能齐全的分子生物学应用软件,它可以对核酸、蛋白质等分子进行大量的操作和分析,以及建立和管理生物数据库。重点对Vector NTI Su ite软件的概况、应用现状及其在分子生物学领域的应用进行综述与探讨。
基金supported by the National Natural Science Foundation of China (No. 11172192)the College Postgraduate Research and Innovation Project of Jiangsu Province (No. CX10B 029Z)the Nominated Excellent Thesis for PHD Candidates Program of Soochow University (No. 23320957)
文摘One of major difficulties in the implementation of meshfree methods using the mov- ing least square （MLS） approximation, such as element-free Galerkin method （EFG）, is the im- position of essential boundary conditions as the approximations do not pass through the nodal parameter values. Another class of meshfree methods based on the radial basis point interpola- tion can satisfy the essential boundary conditions exactly since its approximation function passes through each node in an influence domain and thus its shape functions possess the properties of delta function. In this paper, a coupled element-free Galerkin（EFG）-radial point interpola- tion method （RPIM） is proposed to enhance their advantages and avoid their disadvantages. Discretized equations of equilibrium are obtained in the RPIM region and the EFG region, respectively. Then a collocation approach is introduced to couple the RPIM and the EFG method. This method satisfies the linear consistency exactly and can maintain the stiffness matrix symmetric. Numerical tests show that this method gives reasonably accurate results consistent with the theory.
