胰腺健康与糖尿病等疾病密切相关,准确检测胰腺脂肪含量对疾病的早期诊断和干预具有重要意义.本文提出了一种基于深度学习的胰腺自动分割与脂肪定量方法.首先,使用nnU-Net训练分割模型,实现对m-Dixon序列中胰腺整体的高精度分割,测试集...胰腺健康与糖尿病等疾病密切相关,准确检测胰腺脂肪含量对疾病的早期诊断和干预具有重要意义.本文提出了一种基于深度学习的胰腺自动分割与脂肪定量方法.首先,使用nnU-Net训练分割模型,实现对m-Dixon序列中胰腺整体的高精度分割,测试集DSC系数(Dice Similarity Coefficient,DSC)达0.92.随后,提出一种自动分区与脂肪定量评估方法,实现胰腺头、体、尾的精准划分,并定量分析其体积及脂肪含量.基于256例受试者的研究结果表明,胰腺尾部脂肪含量与2型糖尿病显著相关(p<0.05).进一步利用随机森林分类模型进行糖尿病风险预测,其中基于尾部脂肪含量的分类曲线下面积(Area Under the Curve,AUC)为0.68,而结合多区域脂肪信息构建的组合脂肪含量的分类AUC达0.73.研究结果表明,该方法可为糖尿病的早期诊断提供有效的技术支持.展开更多
On the December 25,2020,Prof.Lu Jie,the Emeritus Professor and former Dean of the Faculty of Education at Nanjing Normal University passed away.The sudden news struck me and recalled my nearly 30 years’friendship wit...On the December 25,2020,Prof.Lu Jie,the Emeritus Professor and former Dean of the Faculty of Education at Nanjing Normal University passed away.The sudden news struck me and recalled my nearly 30 years’friendship with Prof.Lu since 1991,stirring up also my memories of pre-1949 Christian colleges of China,and the promotion of“education of love”at Ginling College and Nanjing Normal University,from the time of Prof.Wu Yifang,Prof.Minnie Vautrin,Prof.Tao Xingzhi and Prof.Lu Jie.In this paper,I shall recall the various meetings with Prof.Lu Jie,and how her life has inspired my re-thinking of the development of“education of love”in China.I shall relate especially her humanistic educational ideals,especially the“education for life”and“cultivating human beings”with Prof.Tao Xingzhi’s“education of love.”Their educational ideals reflected the humanistic education taught at the University of Nanking and Ginling College in the first half of 20th century China.Though the two colleges had brought in a Western style of education,they had exemplified good models of indigenization,especially regarding how humanistic education could become Sinifized in Chinese soil today.展开更多
文摘胰腺健康与糖尿病等疾病密切相关,准确检测胰腺脂肪含量对疾病的早期诊断和干预具有重要意义.本文提出了一种基于深度学习的胰腺自动分割与脂肪定量方法.首先,使用nnU-Net训练分割模型,实现对m-Dixon序列中胰腺整体的高精度分割,测试集DSC系数(Dice Similarity Coefficient,DSC)达0.92.随后,提出一种自动分区与脂肪定量评估方法,实现胰腺头、体、尾的精准划分,并定量分析其体积及脂肪含量.基于256例受试者的研究结果表明,胰腺尾部脂肪含量与2型糖尿病显著相关(p<0.05).进一步利用随机森林分类模型进行糖尿病风险预测,其中基于尾部脂肪含量的分类曲线下面积(Area Under the Curve,AUC)为0.68,而结合多区域脂肪信息构建的组合脂肪含量的分类AUC达0.73.研究结果表明,该方法可为糖尿病的早期诊断提供有效的技术支持.
文摘On the December 25,2020,Prof.Lu Jie,the Emeritus Professor and former Dean of the Faculty of Education at Nanjing Normal University passed away.The sudden news struck me and recalled my nearly 30 years’friendship with Prof.Lu since 1991,stirring up also my memories of pre-1949 Christian colleges of China,and the promotion of“education of love”at Ginling College and Nanjing Normal University,from the time of Prof.Wu Yifang,Prof.Minnie Vautrin,Prof.Tao Xingzhi and Prof.Lu Jie.In this paper,I shall recall the various meetings with Prof.Lu Jie,and how her life has inspired my re-thinking of the development of“education of love”in China.I shall relate especially her humanistic educational ideals,especially the“education for life”and“cultivating human beings”with Prof.Tao Xingzhi’s“education of love.”Their educational ideals reflected the humanistic education taught at the University of Nanking and Ginling College in the first half of 20th century China.Though the two colleges had brought in a Western style of education,they had exemplified good models of indigenization,especially regarding how humanistic education could become Sinifized in Chinese soil today.
