Glyphosate(GLY),a widely used herbicide,has been extensively applied in both the agricultural and non-agricultural sectors worldwide.The rate of GLY use varies considerably depending on the crop type and local farming...Glyphosate(GLY),a widely used herbicide,has been extensively applied in both the agricultural and non-agricultural sectors worldwide.The rate of GLY use varies considerably depending on the crop type and local farming practices,which can be up to approximately 53.5%of agricultural land in certain regions.展开更多
背景:本研究探讨了内脏肥胖指数与美国高血压患病率之间的关系。研究方法:这项横断面研究使用了美国国家健康与营养调查(national health and nutrition examination survey, NHANES)的数据,该调查在2007年至2018年期间连续进行了六次,...背景:本研究探讨了内脏肥胖指数与美国高血压患病率之间的关系。研究方法:这项横断面研究使用了美国国家健康与营养调查(national health and nutrition examination survey, NHANES)的数据,该调查在2007年至2018年期间连续进行了六次,每次为期两年。研究采用多变量逻辑回归和平滑曲线拟合技术,分别研究了高血压患病率与内脏脂肪指数(visceral adiposity index, VAI)之间的关系。利用亚组分析和交互检验对二者之间关系的稳定性进行了检验。结果:在28,743名参与者中,有12,405人患有高血压,16,338人不患有高血压。在对所有协变量进行调整后,VAI与高血压患病率呈显著正相关[OR = 1.07, 95% CI = 1.06~1.08;P Background: This research examined the connection between the visceral obesity index and the prevalence of hypertension in the United States. Methods: This cross-sectional research used data from the National Health and Nutrition Examination Survey (NHANES), conducted in six consecutive two-year cycles between 2007 and 2018. The study employed multivariable logistic regression and smoothing curve fitting techniques to investigate the relationship between the prevalence of hypertension and the visceral adiposity index (VAI), respectively. The stability of the association between them was tested utilizing subgroup analysis and interaction tests. Results: Of the 28,743 participants, 12,405 had hypertension and 16,338 did not. After adjusting for all covariates, VAI was significantly and positively associated with the prevalence of hypertension [odd ratio (OR) = 1.07, 95% confidence interval (CI) 1.06~1.08;P-value < 0.0001] and remained stable after converting VAI to a categorical variable. Subgroup analyses revealed a greater correlation between VAI and the prevalence of hypertension among participants who were female, aged 20~39, without diabetes, or smoked a small number of cigarettes. Conclusions: Higher VAI scores and a greater prevalence of hypertension seem to be correlated. Reducing visceral fat may help reduce the prevalence of hypertension.展开更多
基金supported by grants from the National Key Research and Development Program of China(2023YFC3603100 and 2023YFC3603105)“Leading Goose”R&D Program of Zhejiang(2022C03076-4),China.
文摘Glyphosate(GLY),a widely used herbicide,has been extensively applied in both the agricultural and non-agricultural sectors worldwide.The rate of GLY use varies considerably depending on the crop type and local farming practices,which can be up to approximately 53.5%of agricultural land in certain regions.
文摘背景:本研究探讨了内脏肥胖指数与美国高血压患病率之间的关系。研究方法:这项横断面研究使用了美国国家健康与营养调查(national health and nutrition examination survey, NHANES)的数据,该调查在2007年至2018年期间连续进行了六次,每次为期两年。研究采用多变量逻辑回归和平滑曲线拟合技术,分别研究了高血压患病率与内脏脂肪指数(visceral adiposity index, VAI)之间的关系。利用亚组分析和交互检验对二者之间关系的稳定性进行了检验。结果:在28,743名参与者中,有12,405人患有高血压,16,338人不患有高血压。在对所有协变量进行调整后,VAI与高血压患病率呈显著正相关[OR = 1.07, 95% CI = 1.06~1.08;P Background: This research examined the connection between the visceral obesity index and the prevalence of hypertension in the United States. Methods: This cross-sectional research used data from the National Health and Nutrition Examination Survey (NHANES), conducted in six consecutive two-year cycles between 2007 and 2018. The study employed multivariable logistic regression and smoothing curve fitting techniques to investigate the relationship between the prevalence of hypertension and the visceral adiposity index (VAI), respectively. The stability of the association between them was tested utilizing subgroup analysis and interaction tests. Results: Of the 28,743 participants, 12,405 had hypertension and 16,338 did not. After adjusting for all covariates, VAI was significantly and positively associated with the prevalence of hypertension [odd ratio (OR) = 1.07, 95% confidence interval (CI) 1.06~1.08;P-value < 0.0001] and remained stable after converting VAI to a categorical variable. Subgroup analyses revealed a greater correlation between VAI and the prevalence of hypertension among participants who were female, aged 20~39, without diabetes, or smoked a small number of cigarettes. Conclusions: Higher VAI scores and a greater prevalence of hypertension seem to be correlated. Reducing visceral fat may help reduce the prevalence of hypertension.