Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer cells.These nanophosphors absorb long-wavelength excitation radiation in the infrared or near infr...Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer cells.These nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to infrared.In this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical application.After synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic acid.Folic acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via endocytosis.The sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 nm.Phase structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal system.The photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were measured.These nanophosphors emit in red color with the strongest band at 650 nm under 980 nm excitation.This result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine.展开更多
A polymer waveguide Y-branch power splitter with loss compensation is proposed based on NaYF4:Er^3+, Yb^3+ nanocrystals prepared by a high temperature thermal decomposition method. The Y-branch power splitter is desig...A polymer waveguide Y-branch power splitter with loss compensation is proposed based on NaYF4:Er^3+, Yb^3+ nanocrystals prepared by a high temperature thermal decomposition method. The Y-branch power splitter is designed as a structure of embedded waveguide, and its core material is nanocrystals-doped SU-8. The insertion loss of the device is ~ 15 dB. For an input signal power of 0.05 mW and a pump power of 267.7 mW, the two branches with 5.81-dB and5.41-dB loss compensations at 1530 nm are achieved respectively. A polymer waveguide Y-branch power splitter with loss compensation has an important research significance.展开更多
基金Project supported by Vietnam National Foundation for Science and Technology Development(NAFOSTED,103.03-2017.66)
文摘Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer cells.These nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to infrared.In this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical application.After synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic acid.Folic acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via endocytosis.The sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 nm.Phase structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal system.The photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were measured.These nanophosphors emit in red color with the strongest band at 650 nm under 980 nm excitation.This result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine.
基金Project supported by the Science and Technology Innovation Development Plan of Jilin City,China(Grant No.201830793)the Science and Technology Development Plan of Jilin Province,China(Grant No.20190302010GX)
文摘A polymer waveguide Y-branch power splitter with loss compensation is proposed based on NaYF4:Er^3+, Yb^3+ nanocrystals prepared by a high temperature thermal decomposition method. The Y-branch power splitter is designed as a structure of embedded waveguide, and its core material is nanocrystals-doped SU-8. The insertion loss of the device is ~ 15 dB. For an input signal power of 0.05 mW and a pump power of 267.7 mW, the two branches with 5.81-dB and5.41-dB loss compensations at 1530 nm are achieved respectively. A polymer waveguide Y-branch power splitter with loss compensation has an important research significance.
