Solid-state Na metal batteries(SSNBs),known for the low cost,high safety,and high energy density,hold a significant position in the next generation of rechargeable batteries.However,the urgent challenge of poor interf...Solid-state Na metal batteries(SSNBs),known for the low cost,high safety,and high energy density,hold a significant position in the next generation of rechargeable batteries.However,the urgent challenge of poor interfacial contact in solid-state electrolytes has hindered the commercialization of SSNBs.Driven by the concept of intimate electrode-electrolyte interface design,this study employs a combination of sodium-potassium(NaK)alloy and carbon nanotubes to prepare a semi-solid NaK(NKC)anode.Unlike traditional Na anodes,the paintable paste-like NKC anode exhibits superior adhesion and interface compatibility with both current collectors and gel electrolytes,significantly enhancing the physical contact of the electrode-electrolyte interface.Additionally,the filling of SiO_(2) nanoparticles improves the wettability of NaK alloy on gel polymer electrolytes,further achieving a conformal interface contact.Consequently,the overpotential of the NKC symmetric cell is markedly lower than that of the Na symmetric cell when subjected to a long cycle of 300 hrs.The full cell coupled with Na_(3)V_(2)(PO_(4))_(2) cathodes had an initial discharge capacity of 106.8 mAh·g^(-1) with a capacity retention of 89.61%after 300 cycles,and a high discharge capacity of 88.1 mAh·g^(-1) even at a high rate of 10 C.The outstanding electrochemical performance highlights the promising application potential of the NKC electrode.展开更多
AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retr...AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retrospective cohort study,the data about best corrected visual acuity(BCVA),central macular thickness(CMT),serous macular detachment(SMD),hard exudate,hyperreflective foci(HRF),cystoid degeneration,pearl necklace sign,epiretinal membrane(ERM),disorganization of retinal inner layers(DRIL),ellipsoid zone and external limiting membrane(EZ-ELM)integrity,intraocular pressure(IOP)and lens condition were recorded.RESULTS:Thirty-eight eyes of 38 patients were included in the study.Thirteen patients presented with central RVO(CRVO)and 25 with branch RVO(BRVO).The mean follow-up time was 69.9±15.8mo,and the mean number of injections was 7.9±4.0.The mean BCVA gain was 25.0±36 letters,and this difference was statistically significant(P=0.021).The BCVA gain was 19.4±20.4 letters in the CRVO group,and 26.5±38.6 letters in the BRVO group(P=0.763).Besides,21(55.2%)of the patients achieved≥15 letters improvement.At the end of the follow-up period,SMD was not observed in any of the patients(P=0.016).Hard exudate,HRF number were decreased;while DRIL,ERM and EZ-ELM defects were increased but not significantly.CONCLUSION:Intravitreal dexamethasone monotherapy is an effective and safe treatment option for the treatment-naive RVO-ME patients in the long-term follow-up.展开更多
Tailoring 1D nanotubes with refined interfacial interactions and optimized adsorption sites presents a highly promising yet challenging strategy for advancing Na/Li-ion batteries(SIBs/LIBs).Herein,the intertwined yard...Tailoring 1D nanotubes with refined interfacial interactions and optimized adsorption sites presents a highly promising yet challenging strategy for advancing Na/Li-ion batteries(SIBs/LIBs).Herein,the intertwined yardlong bean-like Fe_(9)Ni_(9)S_(16)/FeS heterostructures with sulfur vacancies encapsulated in N-doped carbon nanotubes(3 N-Fe_(9)Ni_(9)S_(16)/FeS-3@CNTs)are controllably synthesized through Fe/Ni-catalyzed pyrolysis of dicyandiamide followed by sulfidation strategies.1D nanotubes with robust outer walls and internal cavity structures shorten the diffusion paths of ions/electrons and buffer volume expansion and aggregation of active materials.The Fe_(9)Ni_(9)S_(16)/FeS heterostructure provides a powerful driving force for charge transfer by forming built-in electric fields,optimizing ion adsorption,while the Fe_(9)Ni_(9)S_(16)features a wider interlayer spacing that allows for frequent Na+/Li+insertion and extraction,thereby enhancing the reaction kinetics within the electrode.Driven by these synergistic factors,the 3 N-Fe_(9)Ni_(9)S_(16)/FeS-3@CNTs demonstrates remarkable electrochemical performance,achieving a substantial reversible capacity of up to 682.1mA h g^(−1)for SIBs at 0.1 A g^(−1)and 782.7 mA h g^(−1)for LIBs at 0.5 A g−1,alongside exceptional cycling stability in SIBs,maintaining 78.7%of its capacity after 1500 cycles at 1 A g^(−1)coupling with the ether-based electrolyte.Employing various electrochemical analyses in conjunction with ex-situ characterization techniques and Density Functional Theory(DFT)calculations,the storage mechanisms and phase transition processes are investigated,elucidating the structure-composition-performance relationships.This work paves the way for a new strategy in designing advanced materials with engineered heterostructures and controllable defects for energy conversion and storage devices.展开更多
网络协议安全对于互联网信息安全至关重要。目前主流的网络协议漏洞挖掘技术在安全性能、数据完整性、协议解析和逆向漏洞挖掘等方面还存在缺陷。模糊测试因其自动化程度高且能直接获得漏洞概念验证(Proof of Concept,PoC)的特点,在协...网络协议安全对于互联网信息安全至关重要。目前主流的网络协议漏洞挖掘技术在安全性能、数据完整性、协议解析和逆向漏洞挖掘等方面还存在缺陷。模糊测试因其自动化程度高且能直接获得漏洞概念验证(Proof of Concept,PoC)的特点,在协议安全测试中被广泛使用。然而,针对闭源协议的模糊测试,目前还缺少成熟的解决方案。因此,提出了NASFuzz模糊测试框架,能够对闭源NAS协议(NFS、NAS Find协议)进行漏洞挖掘。首先对闭源协议通信字段进行逆向,形成语法语义合规的模板;其次基于该模板,针对性变异字段中的非保留字段进行变异,生成大量的测试字段对协议进行测试。实验显示,NASFuzz模糊测试框架相比黑盒模糊测试框架BooFuzz,其有效样例生成数量高出70%以上,代码覆盖率提升18%,证明NASFuzz对NAS协议的测试相比传统黑盒测试更充分。展开更多
基金National Natural Science Foundation of China (52073253)。
文摘Solid-state Na metal batteries(SSNBs),known for the low cost,high safety,and high energy density,hold a significant position in the next generation of rechargeable batteries.However,the urgent challenge of poor interfacial contact in solid-state electrolytes has hindered the commercialization of SSNBs.Driven by the concept of intimate electrode-electrolyte interface design,this study employs a combination of sodium-potassium(NaK)alloy and carbon nanotubes to prepare a semi-solid NaK(NKC)anode.Unlike traditional Na anodes,the paintable paste-like NKC anode exhibits superior adhesion and interface compatibility with both current collectors and gel electrolytes,significantly enhancing the physical contact of the electrode-electrolyte interface.Additionally,the filling of SiO_(2) nanoparticles improves the wettability of NaK alloy on gel polymer electrolytes,further achieving a conformal interface contact.Consequently,the overpotential of the NKC symmetric cell is markedly lower than that of the Na symmetric cell when subjected to a long cycle of 300 hrs.The full cell coupled with Na_(3)V_(2)(PO_(4))_(2) cathodes had an initial discharge capacity of 106.8 mAh·g^(-1) with a capacity retention of 89.61%after 300 cycles,and a high discharge capacity of 88.1 mAh·g^(-1) even at a high rate of 10 C.The outstanding electrochemical performance highlights the promising application potential of the NKC electrode.
文摘AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retrospective cohort study,the data about best corrected visual acuity(BCVA),central macular thickness(CMT),serous macular detachment(SMD),hard exudate,hyperreflective foci(HRF),cystoid degeneration,pearl necklace sign,epiretinal membrane(ERM),disorganization of retinal inner layers(DRIL),ellipsoid zone and external limiting membrane(EZ-ELM)integrity,intraocular pressure(IOP)and lens condition were recorded.RESULTS:Thirty-eight eyes of 38 patients were included in the study.Thirteen patients presented with central RVO(CRVO)and 25 with branch RVO(BRVO).The mean follow-up time was 69.9±15.8mo,and the mean number of injections was 7.9±4.0.The mean BCVA gain was 25.0±36 letters,and this difference was statistically significant(P=0.021).The BCVA gain was 19.4±20.4 letters in the CRVO group,and 26.5±38.6 letters in the BRVO group(P=0.763).Besides,21(55.2%)of the patients achieved≥15 letters improvement.At the end of the follow-up period,SMD was not observed in any of the patients(P=0.016).Hard exudate,HRF number were decreased;while DRIL,ERM and EZ-ELM defects were increased but not significantly.CONCLUSION:Intravitreal dexamethasone monotherapy is an effective and safe treatment option for the treatment-naive RVO-ME patients in the long-term follow-up.
基金supported by the program of National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future planning(grant number 2022R1A4A1034312,2023R1A2C1007413)by the Commercialization Promotion Agency for R&D Outcomes(COMPA)grant funded by the Korean Government(Ministery of Science and ICT)(RS-2023-00304764)。
文摘Tailoring 1D nanotubes with refined interfacial interactions and optimized adsorption sites presents a highly promising yet challenging strategy for advancing Na/Li-ion batteries(SIBs/LIBs).Herein,the intertwined yardlong bean-like Fe_(9)Ni_(9)S_(16)/FeS heterostructures with sulfur vacancies encapsulated in N-doped carbon nanotubes(3 N-Fe_(9)Ni_(9)S_(16)/FeS-3@CNTs)are controllably synthesized through Fe/Ni-catalyzed pyrolysis of dicyandiamide followed by sulfidation strategies.1D nanotubes with robust outer walls and internal cavity structures shorten the diffusion paths of ions/electrons and buffer volume expansion and aggregation of active materials.The Fe_(9)Ni_(9)S_(16)/FeS heterostructure provides a powerful driving force for charge transfer by forming built-in electric fields,optimizing ion adsorption,while the Fe_(9)Ni_(9)S_(16)features a wider interlayer spacing that allows for frequent Na+/Li+insertion and extraction,thereby enhancing the reaction kinetics within the electrode.Driven by these synergistic factors,the 3 N-Fe_(9)Ni_(9)S_(16)/FeS-3@CNTs demonstrates remarkable electrochemical performance,achieving a substantial reversible capacity of up to 682.1mA h g^(−1)for SIBs at 0.1 A g^(−1)and 782.7 mA h g^(−1)for LIBs at 0.5 A g−1,alongside exceptional cycling stability in SIBs,maintaining 78.7%of its capacity after 1500 cycles at 1 A g^(−1)coupling with the ether-based electrolyte.Employing various electrochemical analyses in conjunction with ex-situ characterization techniques and Density Functional Theory(DFT)calculations,the storage mechanisms and phase transition processes are investigated,elucidating the structure-composition-performance relationships.This work paves the way for a new strategy in designing advanced materials with engineered heterostructures and controllable defects for energy conversion and storage devices.
文摘网络协议安全对于互联网信息安全至关重要。目前主流的网络协议漏洞挖掘技术在安全性能、数据完整性、协议解析和逆向漏洞挖掘等方面还存在缺陷。模糊测试因其自动化程度高且能直接获得漏洞概念验证(Proof of Concept,PoC)的特点,在协议安全测试中被广泛使用。然而,针对闭源协议的模糊测试,目前还缺少成熟的解决方案。因此,提出了NASFuzz模糊测试框架,能够对闭源NAS协议(NFS、NAS Find协议)进行漏洞挖掘。首先对闭源协议通信字段进行逆向,形成语法语义合规的模板;其次基于该模板,针对性变异字段中的非保留字段进行变异,生成大量的测试字段对协议进行测试。实验显示,NASFuzz模糊测试框架相比黑盒模糊测试框架BooFuzz,其有效样例生成数量高出70%以上,代码覆盖率提升18%,证明NASFuzz对NAS协议的测试相比传统黑盒测试更充分。
