Bastnaesite((Ce,La,Pr,Nd)CO_(3)F) is a significant light rare earth mineral found in nature,known for its fine-grained properties.Flotation is commonly employed for the recovery of fine-grained bastnaesite particles.C...Bastnaesite((Ce,La,Pr,Nd)CO_(3)F) is a significant light rare earth mineral found in nature,known for its fine-grained properties.Flotation is commonly employed for the recovery of fine-grained bastnaesite particles.Collectors serve as an essential flotation reagent that enhance the surface hydrophobicity of target minerals.A novel collector,N-hydroxy-9-octadecenamide(N-OH-9-ODA),was synthesised in this study.N-OH-9-ODA exhibits superior selectivity compared to the traditional collector oleic acid in the flotation separation of bastnaesite and fluorite.The experimental and co mputational results indicate that N-OH-9-ODA exhibits superior selectivity due to its higher adsorption affinity for bastnaesite surface compared to fluorite surface.The zeta potential and the binding energies of the Ce 3d peaks in the X-ray photoelectron spectrum(XPS) of bastnaesite surface exhibit significant shifts.Conversely,fluorite surface demonstrates minimal alterations in its zeta potential and the binding energies of the Ca 2p peaks in its XPS after its interaction with N-OH-9-ODA.展开更多
A novel hydroxamic acid,N-hydroxy-9,10-epoxy group-octadecanamide(N-OH-9,10-O-ODA),was synthesised by modifying the structure of oleic acid.The carboxyl group of oleic acid was converted into an N-hydroxy amide group,...A novel hydroxamic acid,N-hydroxy-9,10-epoxy group-octadecanamide(N-OH-9,10-O-ODA),was synthesised by modifying the structure of oleic acid.The carboxyl group of oleic acid was converted into an N-hydroxy amide group,and an epoxy group was introduced into its structure.N-OH-9,10-O-ODA was used as a novel collector in the flotation separation of spodumene from one of its associated gangue minerals,specifically albite.N-OH-9,10-O-ODA exhibits remarkable selectivity,with a stronger affinity for collecting spodumene particles compared to albite particles.Zeta potential measurements and X-ray photoelectron spectroscopic analysis reveal that the adsorption quantity of N-OH-9,10-O-ODA on spodumene surface is comparable to that on albite surface.First-principles calculations demonstrate the diverse adsorption configurations of N-OH-9,10-O-ODA on surfaces of spodumene and albite,leading to its distinct collecting abilities for spodumene and albite particles.展开更多
目的通过研究缺氧缺血性脑病(HIE)新生儿血清神经纤维轻链(NF-L)、水通道蛋白9(AQP9)、纤维蛋白原样蛋白2(FGL2)水平的变化,分析三者与新生儿行为神经评估(NABA)评分的相关性。方法选取2022年1月~2024年7月山西省儿童医院收治的203例HI...目的通过研究缺氧缺血性脑病(HIE)新生儿血清神经纤维轻链(NF-L)、水通道蛋白9(AQP9)、纤维蛋白原样蛋白2(FGL2)水平的变化,分析三者与新生儿行为神经评估(NABA)评分的相关性。方法选取2022年1月~2024年7月山西省儿童医院收治的203例HIE患儿为研究组,根据病情程度分为轻度组(n=63)、中度组(n=81)和重度组(n=59),另选同期的健康新生儿203例为对照组,酶联免疫吸附试验(ELISA)检测血清NF-L、AQP9、FGL2水平,收集分析一般临床资料。受试者操作特征(ROC)曲线分析NF-L、AQP9、FGL2及NABA评分对新生儿重度HIE的诊断价值;Pearson法分析血清NF-L、AQP9、FGL2与NABA评分的相关性。结果与对照组相比,研究组血清NF-L(14.78±1.67ng/ml vs 10.65±1.21ng/ml)、AQP9(61.82±6.29pg/ml vs 42.62±4.31pg/ml)、FGL2(189.69±20.26ng/ml vs 132.51±14.84ng/ml)水平显著升高,差异具有统计学意义(t=28.533、35.877、32.440,均P<0.05);中度组、重度组血清NF-L(14.68±1.67ng/ml、18.62±2.03ng/ml),AQP9(63.51±6.44pg/ml、69.63±7.03pg/ml),FGL2(195.68±20.84ng/ml、210.65±22.36ng/ml)水平显著高于轻度组(11.32±1.33ng/ml、52.32±5.41pg/ml、162.35±17.55ng/ml),NABA(34.89±3.51分、29.88±3.43分)评分显著低于轻度组(36.54±1.52分),差异具有统计学意义(t_(中度组)=4.616~16.729,t_(重度组)=17.276~33.701,均P<0.05);NF-L、AQP9、FGL2与NABA评分均呈负相关(r=-0.432、-0.421、-0.402,均P<0.05);NF-L、AQP9、FGL2、NABA联合诊断患儿重度病情的曲线下面积(AUC)显著高于各项单独诊断,差异具有统计学意义(Z=2.066~3.307,均P<0.05)。结论HIE患儿血清NF-L、AQP9、FGL2水平显著升高,与NABA评分相关,可能成为评估HIE患儿病情的标志物。展开更多
基金supported by National Natural Science Foundation of China (52104287,91962223)Hubei Key Laboratory for Efficient Utilisation and Agglomeration of Metallurgic Mineral ResourcesOpen Foundation of State Key Laboratory of Mineral Processing (BGRIMM-KJSKL-2022-14)。
文摘Bastnaesite((Ce,La,Pr,Nd)CO_(3)F) is a significant light rare earth mineral found in nature,known for its fine-grained properties.Flotation is commonly employed for the recovery of fine-grained bastnaesite particles.Collectors serve as an essential flotation reagent that enhance the surface hydrophobicity of target minerals.A novel collector,N-hydroxy-9-octadecenamide(N-OH-9-ODA),was synthesised in this study.N-OH-9-ODA exhibits superior selectivity compared to the traditional collector oleic acid in the flotation separation of bastnaesite and fluorite.The experimental and co mputational results indicate that N-OH-9-ODA exhibits superior selectivity due to its higher adsorption affinity for bastnaesite surface compared to fluorite surface.The zeta potential and the binding energies of the Ce 3d peaks in the X-ray photoelectron spectrum(XPS) of bastnaesite surface exhibit significant shifts.Conversely,fluorite surface demonstrates minimal alterations in its zeta potential and the binding energies of the Ca 2p peaks in its XPS after its interaction with N-OH-9-ODA.
基金financial support from the National Natural Science Foundation of China(Nos.91962223,52104287,U2067201)Hubei Key Laboratory for Efficient Utilization and Agglomeration of Metallurgic Mineral Resources and Open Foundation of State Key Laboratory of Mineral Processing,China(No.BGRIMM-KJSKL-2022-14)。
文摘A novel hydroxamic acid,N-hydroxy-9,10-epoxy group-octadecanamide(N-OH-9,10-O-ODA),was synthesised by modifying the structure of oleic acid.The carboxyl group of oleic acid was converted into an N-hydroxy amide group,and an epoxy group was introduced into its structure.N-OH-9,10-O-ODA was used as a novel collector in the flotation separation of spodumene from one of its associated gangue minerals,specifically albite.N-OH-9,10-O-ODA exhibits remarkable selectivity,with a stronger affinity for collecting spodumene particles compared to albite particles.Zeta potential measurements and X-ray photoelectron spectroscopic analysis reveal that the adsorption quantity of N-OH-9,10-O-ODA on spodumene surface is comparable to that on albite surface.First-principles calculations demonstrate the diverse adsorption configurations of N-OH-9,10-O-ODA on surfaces of spodumene and albite,leading to its distinct collecting abilities for spodumene and albite particles.
文摘目的通过研究缺氧缺血性脑病(HIE)新生儿血清神经纤维轻链(NF-L)、水通道蛋白9(AQP9)、纤维蛋白原样蛋白2(FGL2)水平的变化,分析三者与新生儿行为神经评估(NABA)评分的相关性。方法选取2022年1月~2024年7月山西省儿童医院收治的203例HIE患儿为研究组,根据病情程度分为轻度组(n=63)、中度组(n=81)和重度组(n=59),另选同期的健康新生儿203例为对照组,酶联免疫吸附试验(ELISA)检测血清NF-L、AQP9、FGL2水平,收集分析一般临床资料。受试者操作特征(ROC)曲线分析NF-L、AQP9、FGL2及NABA评分对新生儿重度HIE的诊断价值;Pearson法分析血清NF-L、AQP9、FGL2与NABA评分的相关性。结果与对照组相比,研究组血清NF-L(14.78±1.67ng/ml vs 10.65±1.21ng/ml)、AQP9(61.82±6.29pg/ml vs 42.62±4.31pg/ml)、FGL2(189.69±20.26ng/ml vs 132.51±14.84ng/ml)水平显著升高,差异具有统计学意义(t=28.533、35.877、32.440,均P<0.05);中度组、重度组血清NF-L(14.68±1.67ng/ml、18.62±2.03ng/ml),AQP9(63.51±6.44pg/ml、69.63±7.03pg/ml),FGL2(195.68±20.84ng/ml、210.65±22.36ng/ml)水平显著高于轻度组(11.32±1.33ng/ml、52.32±5.41pg/ml、162.35±17.55ng/ml),NABA(34.89±3.51分、29.88±3.43分)评分显著低于轻度组(36.54±1.52分),差异具有统计学意义(t_(中度组)=4.616~16.729,t_(重度组)=17.276~33.701,均P<0.05);NF-L、AQP9、FGL2与NABA评分均呈负相关(r=-0.432、-0.421、-0.402,均P<0.05);NF-L、AQP9、FGL2、NABA联合诊断患儿重度病情的曲线下面积(AUC)显著高于各项单独诊断,差异具有统计学意义(Z=2.066~3.307,均P<0.05)。结论HIE患儿血清NF-L、AQP9、FGL2水平显著升高,与NABA评分相关,可能成为评估HIE患儿病情的标志物。
