Background The retinal image quality derived from lower-order(LOA)and higher-order aberrations(HOA)for fixed 3-mm and photopic pupil diameters,in children undergoing combined 0.01%atropine and orthokeratology(AOK)vers...Background The retinal image quality derived from lower-order(LOA)and higher-order aberrations(HOA)for fixed 3-mm and photopic pupil diameters,in children undergoing combined 0.01%atropine and orthokeratology(AOK)versus those receiving orthokeratology alone(OK)over two years was evaluated.Methods The visual Strehl ratio based on the optical transfer function(VSOTF),derived from 2nd-to 4th-order terms(LOA and HOA combined),2nd-order terms(LOA only),and 3rd-to 4th-order terms(HOA only)for fixed 3-mm and natural photopic pupil diameters,was compared between the two treatment groups.The individual Zernike coef-ficients fora fixed 3-mm pupil ize of 2nd to 4th,orders,root mean square(RMS)of LOA(Z_(2)^(0),Z_(2)^(-2),and Z_(2)^(2) combined),HOA(3rd to 4th orders inclusive),and coma(Z_(3)^(-1) and Z_(3)^(1) combined)were also compared between the two groups.Results Right eye data of 33 AOK and 35 OK participants were analysed.Under photopic conditions,significantly lower VSOTF based on HOA only was observed in the AOK group compared with that in the OK group at all post-treatment visits(all P<0.05);however,interactions between HOA and LOA resulted in comparable overall retinal image quality(i.e.,VSOTF based on LOA and HOA combined)between the two groups at all visits(all P>0.05).For a fixed 3-mm pupil size,the VSOTF based on HOA only,LOA only,or HOA and LOA combined,were not different between the two groups(all P>0.05).AOK participants had slower axial elongation(mean±SD,0.17±0.19 mm vs.0.35±0.20 mm,P<0.001),a larger photopic pupil size(4.05±0.61 mm vs.3.43±0.41 mm,P<0.001)than OK partici-pants overtwoyears.Conclusions HOA profile related to an enlarged pupil size may provide visual signal influencing eye growth in the AOK group.展开更多
基金supported by The Hong Kong Polytechnic University Teaching Postgraduate Studentship(TPS)Scheme to QiTansupported by a private donation to the School of Optometry,The Hong Kong Polytechnic University.
文摘Background The retinal image quality derived from lower-order(LOA)and higher-order aberrations(HOA)for fixed 3-mm and photopic pupil diameters,in children undergoing combined 0.01%atropine and orthokeratology(AOK)versus those receiving orthokeratology alone(OK)over two years was evaluated.Methods The visual Strehl ratio based on the optical transfer function(VSOTF),derived from 2nd-to 4th-order terms(LOA and HOA combined),2nd-order terms(LOA only),and 3rd-to 4th-order terms(HOA only)for fixed 3-mm and natural photopic pupil diameters,was compared between the two treatment groups.The individual Zernike coef-ficients fora fixed 3-mm pupil ize of 2nd to 4th,orders,root mean square(RMS)of LOA(Z_(2)^(0),Z_(2)^(-2),and Z_(2)^(2) combined),HOA(3rd to 4th orders inclusive),and coma(Z_(3)^(-1) and Z_(3)^(1) combined)were also compared between the two groups.Results Right eye data of 33 AOK and 35 OK participants were analysed.Under photopic conditions,significantly lower VSOTF based on HOA only was observed in the AOK group compared with that in the OK group at all post-treatment visits(all P<0.05);however,interactions between HOA and LOA resulted in comparable overall retinal image quality(i.e.,VSOTF based on LOA and HOA combined)between the two groups at all visits(all P>0.05).For a fixed 3-mm pupil size,the VSOTF based on HOA only,LOA only,or HOA and LOA combined,were not different between the two groups(all P>0.05).AOK participants had slower axial elongation(mean±SD,0.17±0.19 mm vs.0.35±0.20 mm,P<0.001),a larger photopic pupil size(4.05±0.61 mm vs.3.43±0.41 mm,P<0.001)than OK partici-pants overtwoyears.Conclusions HOA profile related to an enlarged pupil size may provide visual signal influencing eye growth in the AOK group.
