Objective:Microvascular invasion(MVI)is an important risk factor for early recurrence after hepatectomy for hepatocellular carcinoma(HCC).However,it lacks the systemic evidence of the tissue sampling protocol for effi...Objective:Microvascular invasion(MVI)is an important risk factor for early recurrence after hepatectomy for hepatocellular carcinoma(HCC).However,it lacks the systemic evidence of the tissue sampling protocol for efficient MVI detection.This study aims to explore the relationship between the number of sampling sites(NuSS)crossing the tumor interface,the paracancerous parenchyma,and the positive rate of MVI.展开更多
Global warming caused primarily by excessive emissions of CO_(2) has attracted worldwide attention.Herein,three 2-hydroxypyridium ionic liquids(ILs)based task-specific deep eutectic solvents(DESs)were synthesized to a...Global warming caused primarily by excessive emissions of CO_(2) has attracted worldwide attention.Herein,three 2-hydroxypyridium ionic liquids(ILs)based task-specific deep eutectic solvents(DESs)were synthesized to absorb CO_(2) and physical properties including density,viscosity,and melting points were measured to explore the effect on CO_(2) absorption.The CO_(2) absorption capacities of the ILs-based task-specific DESs were investigated at different pressures and temperatures,which showed that the maximum absorption capacity of the DES was up to 1.48 molCO_(2)·molDES^(-1) or 0.233 gCO_(2)·gDES^(-1) at the atmospheric pressure and 25℃.The plausible absorption mechanism was also proposed by a combination of 1:1 and 2:1 stoichiometric reactions of CO_(2) and the IL-based task-specific DES via multiple-site absorption,which was confirmed by ^(13)C and ^(1)H nuclear magnetic resonance(NMR),Fourier transform infrared(FT-IR)spectroscopy,quantum chemical calculation,and reaction equilibrium thermodynamic modeling.The thermodynamic properties,including absorption Gibbs free energy,absorption enthalpy,and absorption entropy were rationally deduced and explained.Furthermore,the excellent CO_(2) absorption capacity and regenerability of multiple-site task-specific DES make it a new environmentally eco-friendly choice for highly efficient CO_(2) absorption and subsequent CO_(2) transformation.展开更多
The EPICⅢstudy showed that 52%of patients admitted to the intensive care unit(ICU)have infectious diseases and that the incidence of ICU-acquired infections is increasing,leading to longer ICU stays and higher mortal...The EPICⅢstudy showed that 52%of patients admitted to the intensive care unit(ICU)have infectious diseases and that the incidence of ICU-acquired infections is increasing,leading to longer ICU stays and higher mortality rates.Multiple-site decontamination,a type of selective decontamination program,has been associated with a reduction in the incidence of ICU-acquired infection and decreased mortality rates in some critically ill patients.However,the standardized implementation and actual effectiveness of multiple-site decontamination require further investigation.展开更多
文摘Objective:Microvascular invasion(MVI)is an important risk factor for early recurrence after hepatectomy for hepatocellular carcinoma(HCC).However,it lacks the systemic evidence of the tissue sampling protocol for efficient MVI detection.This study aims to explore the relationship between the number of sampling sites(NuSS)crossing the tumor interface,the paracancerous parenchyma,and the positive rate of MVI.
基金financial support from the National Natural Science Foundation of China(22278134,22472055)。
文摘Global warming caused primarily by excessive emissions of CO_(2) has attracted worldwide attention.Herein,three 2-hydroxypyridium ionic liquids(ILs)based task-specific deep eutectic solvents(DESs)were synthesized to absorb CO_(2) and physical properties including density,viscosity,and melting points were measured to explore the effect on CO_(2) absorption.The CO_(2) absorption capacities of the ILs-based task-specific DESs were investigated at different pressures and temperatures,which showed that the maximum absorption capacity of the DES was up to 1.48 molCO_(2)·molDES^(-1) or 0.233 gCO_(2)·gDES^(-1) at the atmospheric pressure and 25℃.The plausible absorption mechanism was also proposed by a combination of 1:1 and 2:1 stoichiometric reactions of CO_(2) and the IL-based task-specific DES via multiple-site absorption,which was confirmed by ^(13)C and ^(1)H nuclear magnetic resonance(NMR),Fourier transform infrared(FT-IR)spectroscopy,quantum chemical calculation,and reaction equilibrium thermodynamic modeling.The thermodynamic properties,including absorption Gibbs free energy,absorption enthalpy,and absorption entropy were rationally deduced and explained.Furthermore,the excellent CO_(2) absorption capacity and regenerability of multiple-site task-specific DES make it a new environmentally eco-friendly choice for highly efficient CO_(2) absorption and subsequent CO_(2) transformation.
基金supported by the Project of the Key Laboratory of Multiple Organ Failure,Ministry of Education(2023KF07)the Key Laboratory of Intelligent Pharmacy and Individualized Treatment in Huzhou City(HZKF-20240101)the Guangxi Key Laboratory for Diagnosis and Treatment of Acute Respiratory Distress Syndrome(ZZH2020013-3),China.
文摘The EPICⅢstudy showed that 52%of patients admitted to the intensive care unit(ICU)have infectious diseases and that the incidence of ICU-acquired infections is increasing,leading to longer ICU stays and higher mortality rates.Multiple-site decontamination,a type of selective decontamination program,has been associated with a reduction in the incidence of ICU-acquired infection and decreased mortality rates in some critically ill patients.However,the standardized implementation and actual effectiveness of multiple-site decontamination require further investigation.
