Macroamylasemia is a condition of elevated serum amylase levels in which normal serum amylase form a complex with high molecular weight proteins such as immunoglobulins. This is a case report on a patient with macroam...Macroamylasemia is a condition of elevated serum amylase levels in which normal serum amylase form a complex with high molecular weight proteins such as immunoglobulins. This is a case report on a patient with macroamylasemia following acute asthmatic bronchitis. A 5-year-old male with cerebral palsy and developmental retardation was admitted to our hospital because of high fever and severe cough. Treatment of the respiratory symptoms provided symptomatic improvement, but the serum amylase levels became suddenly elevated. Although acute pancreatitis associated with respiratory infection was initially suspected, a predominant salivary isoamylase, normal serum lipase level, low urine amylase level, and low amylase-creatinine clearance ratio (ACCR) (0.58%) indicated macroamylasemia. The serum amylase level decreased, and the ACCR increased within normal range 2 weeks after discharge. Both of these indicators have been within normal range over the past year. Transient macroamylasemia can be misdiagnosed as acute pancreatitis, especially in a severely multiple-handicapped child who is unable to complain. The ACCR is useful in the diagnosis of macroamylasemia.展开更多
Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent depression.However,many adolescent depression treatment guidelines stil...Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent depression.However,many adolescent depression treatment guidelines still recommend the use of antidepressants,especially specific serotonin re-uptake inhibitors.Previous studies have suggested that antidepressants have little therapeutic effect but many side effects,such as switching to mania,suicide,and non-suicidal self injury(NSSI),in the treatment of child and adolescent depression.In the process of developing guidelines,drug recommendations should not only focus on impro-ving symptoms,but they should also consider potential side effects.This review discusses the serious side effects of antidepressants,including switching to mania,suicide,and NSSI.展开更多
Objective To investigate the growth parameters of children with phenylketonuria and assess the impact of a phenylalanine-restricted diet on their physical development.Methods The study involved 39 children diagnosed w...Objective To investigate the growth parameters of children with phenylketonuria and assess the impact of a phenylalanine-restricted diet on their physical development.Methods The study involved 39 children diagnosed with phenylketonuria through newborn screening at the Central Child Teaching Hospital,Baghdad,Iraq.Data were collected during scheduled monthly check-ups,including phenylalanine levels,diet compliance,and anthropometric measurements.The children were divided into two groups based on their phenylalanine levels during the 3-year follow up period:well-controlled group(average phenylalanine level of less than 360μmol/L,with no single reading exceeding 600μmol/L;n=14)and poorly-controlled group(one or more phenylalanine readings above 600μmol/L during the follow-up period;n=25).Results The mean height readings for all time points(at birth and 3,6,9,12,15,18,21,24 and 36 months of age)were higher in the well-controlled group than the poorly-controlled group,however,only at 3 months of age the difference was statistically significant.Height Z-scores revealed a clearer pattern:although the poorly controlled group had higher height Z-scores at birth(P=0.001),the well-controlled group showed significantly higher height Z-scores at 3,6,12,15,18,24,and 36 months(P<0.05).The well-controlled group exhibited significantly higher mean weight measurements compared to the poorly-controlled group at 3,6,9,15,18 months and 21 months(P<0.05).From 6 to 36 months,the well-controlled group consistently had significantly higher weight Z-scores than the poorly controlled group(P<0.05).The well-controlled group showed more favorable height and weight Z-score distributions at 36 months of age compared to the poorly-controlled group,but the differences were not statistically significant(P>0.05).Both groups had height and weight Z-scores within the normal range at 36 months of age.Conclusions The children with phenylketonuria who receive good dietary control show better improvements in growth parameters compared to those with poor dietary control,however,both groups maintain height and weight Z-scores within the normal range,indicating generally adequate physical development across the cohort.展开更多
BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications...BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.展开更多
Introduction: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a sleep-related breathing disorder characterized by repeated episodes of partial obstruction of the upper airways (hypopnea) and/or intermittent compl...Introduction: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a sleep-related breathing disorder characterized by repeated episodes of partial obstruction of the upper airways (hypopnea) and/or intermittent complete obstruction (apnea). Our aim is to study the role of adeno-tonsillectomy in the management of OSAHS in children. Methodology: This was a prospective descriptive study conducted in the ENT-Head and Neck Surgery department of Ignace Deen National Hospital over a six-month period. We included in our study all patients aged 0 to 15 years, presenting with OSAHS of ENT etiology and who had undergone tonsillectomy/adenoidectomy. Results: The frequency of OSAHS was 13%. The mean age of our patients was 5.1 ± 3.8 years. There was a predominance of males (69.6%) with a sex ratio of 2.28. Snoring (98.6%), nasal obstruction (97.1%), and mouth breathing (96.6%) were the main reasons for consultation. Adeno-tonsillectomy (45.4%) was the primary surgical intervention. Almost all children (99.0%) had a simple postoperative course. Conclusion: OSAHS is a condition with a multifactorial etiology. Adeno-tonsillectomy remains the first-line surgical treatment to prevent severe complications and relieve the patient. Multidisciplinary collaboration is essential in the management of OSAHS.展开更多
Domestic accidents (DA) are common in children and responsible for high morbidity and mortality in developed countries. Objective: This work aimed to describe the epidemiological profile of AD in children aged 0 to 15...Domestic accidents (DA) are common in children and responsible for high morbidity and mortality in developed countries. Objective: This work aimed to describe the epidemiological profile of AD in children aged 0 to 15 years in Libreville. Materials and Methods: All children aged 0 to 15 years who were victims of unintentional trauma occurring at home or in its immediate surroundings were included. We studied the mother’s age, family situation, socioeconomic level, type of housing, age and sex of the child, characteristics of AD and their management. Results: The majority of mothers lived in an intermediate dwelling (80.6%). They were married (37.1%), middle managers (58.2%) and of average socioeconomic level (60.5%). The average age of the mothers was 39.9 ± 11.4 years. Families with more than three children were most exposed (39.2%) to the occurrence of AD. The average age of the children was 6.5 ± 3.3 years with a male predominance. The sex ratio was 1.8. The most common ADs were falls (34.7%), followed by cuts (22.3%) and burns (17.7%). Wounds (54.4%), followed by burns (33%) and fractures (5.1%) were the main types of injuries. The upper limbs were the most affected body part (33.9%) followed by the lower limbs (30.1%) and the head (27.3%). The yard was the preferred location for ADs to occur (51.1%), and particularly during the holiday period (48.4%). The risk factors related to the occurrence of AD were age, socioeconomic level, number of children and type of housing. Care was provided at home in 51.9% of cases. Conclusion: The occurrence of AD in children is not negligible;hence the need to implement preventive measures to minimize their frequency.展开更多
BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term so...BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term socioeconomic challenges for families and communities.Although its impact on child growth and development is a pressing concern,research remains limited particularly in multicenter settings.AIM To examine the long-term consequences of unintended pregnancy on the critical years of early childhood growth and development.METHODS This analytical observational study employed a case-control design and was conducted in research centers across Indonesia,encompassing those located in Central Java,Lampung,Bali,and West Nusa Tenggara.A total of 700 children aged≤5 years with histories of intended or unintended pregnancies participated.Data collection involved structured interviews and direct anthropometric and developmental assessments.Data analyses were conducted using multivariate statistics and partial least squares structural equation modeling.RESULTS Unintended pregnancy was found to have a statistically significant effect on both child growth(t=8.178;P<0.001)and child development(t=25.688;P<0.001).Key growth problems identified included underweight,undernutrition,abnormal head circumference,and stunting.Developmental challenges prominently associated with unintended pregnancy included behavioral and emotional disorders,autism spectrum disorder,attentiondeficit/hyperactivity disorder,social and motor skill deficits,as well as visual and hearing impairments.CONCLUSION Unintended pregnancy significantly affects child growth and development,underscoring the need for early intervention,quality prenatal care,and strengthened family planning policies.展开更多
Objective:Many children with fully corrected congenital heart disease(CHD)avoid physicalactivity(PA).This descriptive study sought to determine child and parental factors that could predict PAlevels in Thai dhildren a...Objective:Many children with fully corrected congenital heart disease(CHD)avoid physicalactivity(PA).This descriptive study sought to determine child and parental factors that could predict PAlevels in Thai dhildren after corrective surgery.Methods:Ninety schoolaged children with fully correctedCHD were recruited from a cardiology clinic at a university hospital in northern Thailand.Data collectioninvolved five validated questionnaires:(1)the Modified Thai Adolescent's Fhysical Activity Questionnaire,(2)the Child Health Status Questionnaire-Forms I and II1,(3)the Parental Knowledge on School-agedChildrer's PhysicalActivity Scale,(4)the Perceived Self-efficacy to Physical Activity Questionnaire,and(5)the Parntal Bonding Instrument.The analysis included descriptive statistics and stepwise multipleregression.Results:Results showed that the physical activity(PA.)levels,assessed through total energyexpenditure,of child ran with CHD were below the recommended levels after treatment(t=-8.33,p<0.001).There were sigrificant correlations between PA and factors such as a child's perceived health status,PAself-efficacy,and parentaloverprotection(r=0.39,p<0.050;r=0.46,p<0.050;r=0.25,p<0.050,respectively).After adjustment for demographic data and CHD type,these factors had no association with a child's PA.Only two factors predicted childhood PA—the child's perceived health status and PA self-efficacy whichcould explain27.3%of the variance of PA.(p<0.001).Conclusion:The study highlights the necessity forinterventions to enhance childrer's perception of their health status and PA self-efficacy to increase theirphysical activity levels.展开更多
We investigated the psychological effects of nail treatments on children living in child welfare facilities.We performed a single nail treatment on children living in child welfare facilities.As a result,we found that...We investigated the psychological effects of nail treatments on children living in child welfare facilities.We performed a single nail treatment on children living in child welfare facilities.As a result,we found that feelings of“energy”,“relaxation”,and“comfort”tended to increase more strongly after the treatment than before.Furthermore,these feelings increased even more after the nail treatment.The effects of nail treatments were unrelated to gender or previous nail experience.Furthermore,nail treatments increased communication and interaction with facility staff and other children residing in the facility,promoting self-expression,and,as a result,increasing a sense of accomplishment,acceptance from others,and self-esteem.This suggests that positive emotions persisted even after nail treatments,leading to positive changes in daily life.展开更多
The usage characteristics of the large numerals in child language reflects both linguistic and cognitive development.The present study systematically examined Mandarin children’s naturalistic use of large numerals“...The usage characteristics of the large numerals in child language reflects both linguistic and cognitive development.The present study systematically examined Mandarin children’s naturalistic use of large numerals“bai”,“qian”,and“wan”and compared it with adult usage patterns based on a self-constructed corpus.The results revealed a significant preference for the use of“bai”over both“qian”and“wan”among children and adults alike.This shared pattern suggests that children’s acquisition of large numerals is strongly shaped by adult language input.This study addresses a critical gap in research on the acquisition of large numerals by Mandarin-speaking children,providing valuable insights for the broader theoretical framework of cross-linguistic numerical cognition.展开更多
BACKGROUND Oral food challenge(OFC)is an integral part of confirming and evaluating the diagnosis of food allergy(FA),and most incidents of FA occur in children.FA significantly impairs the quality of life(QoL)and cau...BACKGROUND Oral food challenge(OFC)is an integral part of confirming and evaluating the diagnosis of food allergy(FA),and most incidents of FA occur in children.FA significantly impairs the quality of life(QoL)and causes limited activities outside the home for children and their parents.AIM To evaluate the effect of OFC on QoL and family activities in children with FA.METHODS This prospective study identified children suspected of FA using a skin prick test(SPT)between January 2022 and December 2024.These children conduct an elimination diet for 4 wk,followed by OFC under protocol.Rating scales eva-luated QoL using pediatric QoL inventory and family activities using family ac-tivities impact scale(FAIS),in which data are collected before and after an elimination diet and OFC.Statistical analysis utilized χ^(2),Spearman,paired t,Wilcoxon,independent t,and Mann–Whitney tests,with P<0.05 considered significant.RESULTS Most participants were boys(137;65.55%);102(64.56%)had a positive OFC and 92.40±4.22 after OFC(Z=12.537;P<0.001).In the FAIS score,the average result before OFC was 5.36±0.68 and 4.10±0.38 after OFC,which was a significant difference(Z=12.162;P<0.001).Although the difference in QoL before and after increased,and FAIS reduced,there was no significant difference.Additionally,most results of positive SPT are higher than positive OFC in each specific food allergen.CONCLUSION OFC may improve QoL and FAIS in children with FA and their families as it increases activities outside the home and reduces worry about allergen exposure.展开更多
Objectives:To evaluate the occurrence of depression and its related factors among public health nurses(PHNs)engaged in child neglect-related abuse cases.Methods:A cross-sectional study of PHNs involved in maternal and...Objectives:To evaluate the occurrence of depression and its related factors among public health nurses(PHNs)engaged in child neglect-related abuse cases.Methods:A cross-sectional study of PHNs involved in maternal and child health or child and family welfare,and engaged in cases of child neglect-related abuse was conducted from January to March 2023 in all municipalities of 13 prefectures selected from Japan's seven regions,considering geographic diversity and major urban areas.The Patient Health Questionnaire-2 was used to screen for depression.Statistical analyses included the Chi-square test,Mann-Whitney U test,and logistic regression analysis.Results:A total of 359 provided valid responses.Among them,11.4%screened positive for depression.Significant individual factors related depression were management-stage nurses(OR=6.27,95%CI:1.63-24.18),no disability welfare experience(OR=3.49,95%CI:1.05-11.55),being assignment of highrisk cases within the past year(OR=8.28,95%CI:2.07-33.08),and lower work control(OR=0.53,95%CI:0.32-0.86).Workplace environment factors were lower perceptions and relationships within the workplace(OR=0.43,95%CI:0.29-0.65)and perceiving manpower as not secured(OR=9.07,95%CI:1.17-70.40),Conclusions:Mental health measures for PHNs should include workload management and reduced burdens through workforce enhancement,attention to burdens on managerial PHNs,promoting communication and mutual support,and opportunities to engage in disability welfare work.展开更多
With the widespread adoption of smartphones,parental phubbing behaviors have become increasingly prevalent,potentially affecting preschool children’s development.Current research primarily focuses on adolescent popul...With the widespread adoption of smartphones,parental phubbing behaviors have become increasingly prevalent,potentially affecting preschool children’s development.Current research primarily focuses on adolescent populations,while the mechanisms through which parental phubbing and authoritarian parenting style influence preschool children’s behavioral problems within the Chinese cultural context remain to be explored.Our investigation seeks to examine the factors contributing to behavioral difficulties among children of preschool age and provide theoretical guidance for prevention.Methods In our research,we utilized a convenience sampling approach to collect data from parents whose children(n=612)were between 3 and 7 years of age.The questionnaire distribution was facilitated via the Wenjuanxing online survey platform.Research instruments included the Parental Phubbing Scale,Parent-Child Relationship Scale,Authoritarian Parenting Style Scale,and Conners Child Behavior Rating Scale.For analytical procedures,we employed SPSS 24.0 to generate descriptive statistics and correlation analysis.Chain mediation effects were examined via Process macro,while significance assessment of the mediating effects relied on the Bootstrap method for constructing 95%confidence intervals.Results A statistically significant positive association was observed between parental phubbing and behavioral problems exhibited by children(r=0.251,p<0.001).Parental phubbing exhibited a significant direct effect on children’s behavioral problems(β=0.088,p<0.001).Analysis of sequential mediation demonstrated that authoritarian parenting style together with parent-child conflict functioned as significant intermediary variables in the relationship between parental phubbing and children’s problem behaviors(β=0.163,p<0.001),with these indirect pathways constituting 64.94%of the total effect.Conclusion Parental phubbing significantly contributes to behavioral problems in preschool children.Parents should monitor their media use,improve their parenting approach,and enhance parent-child relationships to reduce behavioral problems in preschool children.展开更多
BACKGROUND China has recently encountered severe challenges associated with population aging.Parents of first-generation only children face significant challenges regarding elderly care needs and the associated negati...BACKGROUND China has recently encountered severe challenges associated with population aging.Parents of first-generation only children face significant challenges regarding elderly care needs and the associated negative emotions.AIM To analyze the elderly care needs of first-generation only child parents in China and identify factors that influence negative emotions.METHODS This study used a cross-sectional design.Convenience sampling was used to select 1580 elderly individuals who met the inclusion criteria in a Chinese city between June and September 2022.A questionnaire was administered to collect general information about participants.Depression and anxiety were assessed using the patient health questionnaire-9 and generalized anxiety disorder-7 scale,respectively.A logistic regression analysis was performed to evaluate the relevant correlations.RESULTS Among 1580 first-generation only child parents,1120(70.89%)preferred family based care,324(20.51%)opted for community care,and 136(8.61%)chose institutional care,with 460(29.11%)reporting negative emotions.Significant differences in the distribution of negative emotions among only child parents were observed based on age,marital status,living conditions,disability,type of chronic disease,frailty status,and family support(P<0.05).The regression analysis indicated that disability,type of chronic disease,living environment,frailty status,and level of family support were independent risk factors for negative emotions among parents with only children(P<0.05).CONCLUSION Elderly care for parents of only children is primarily family-based.Independent risk factors for negative emotions in this group include disability,chronic disease type,and living environment.展开更多
Objective:To explore the impact of parenting care guidance combined with preventive healthcare on child family parenting.Methods:Ninety-two child families were included as research subjects and randomly divided into a...Objective:To explore the impact of parenting care guidance combined with preventive healthcare on child family parenting.Methods:Ninety-two child families were included as research subjects and randomly divided into a control group and an observation group,with 46 cases in each group.The former implemented basic preventive healthcare,while the latter simultaneously carried out parenting care guidance combined with preventive healthcare.The intervention results of the two groups were compared.Results:The observation group had a higher awareness rate of family parenting knowledge and a higher formation rate of healthy behaviors,P<0.05.At the same time,parents’parenting anxiety scores were lower,and family health management ability scores were higher,P<0.05.Moreover,the observation group showed higher scores in children’s social skills,P<0.05.Conclusion:Parenting care guidance combined with preventive healthcare can effectively improve the status of child family parenting,and it is worthy of promotion and application.展开更多
文摘Macroamylasemia is a condition of elevated serum amylase levels in which normal serum amylase form a complex with high molecular weight proteins such as immunoglobulins. This is a case report on a patient with macroamylasemia following acute asthmatic bronchitis. A 5-year-old male with cerebral palsy and developmental retardation was admitted to our hospital because of high fever and severe cough. Treatment of the respiratory symptoms provided symptomatic improvement, but the serum amylase levels became suddenly elevated. Although acute pancreatitis associated with respiratory infection was initially suspected, a predominant salivary isoamylase, normal serum lipase level, low urine amylase level, and low amylase-creatinine clearance ratio (ACCR) (0.58%) indicated macroamylasemia. The serum amylase level decreased, and the ACCR increased within normal range 2 weeks after discharge. Both of these indicators have been within normal range over the past year. Transient macroamylasemia can be misdiagnosed as acute pancreatitis, especially in a severely multiple-handicapped child who is unable to complain. The ACCR is useful in the diagnosis of macroamylasemia.
文摘Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent depression.However,many adolescent depression treatment guidelines still recommend the use of antidepressants,especially specific serotonin re-uptake inhibitors.Previous studies have suggested that antidepressants have little therapeutic effect but many side effects,such as switching to mania,suicide,and non-suicidal self injury(NSSI),in the treatment of child and adolescent depression.In the process of developing guidelines,drug recommendations should not only focus on impro-ving symptoms,but they should also consider potential side effects.This review discusses the serious side effects of antidepressants,including switching to mania,suicide,and NSSI.
文摘Objective To investigate the growth parameters of children with phenylketonuria and assess the impact of a phenylalanine-restricted diet on their physical development.Methods The study involved 39 children diagnosed with phenylketonuria through newborn screening at the Central Child Teaching Hospital,Baghdad,Iraq.Data were collected during scheduled monthly check-ups,including phenylalanine levels,diet compliance,and anthropometric measurements.The children were divided into two groups based on their phenylalanine levels during the 3-year follow up period:well-controlled group(average phenylalanine level of less than 360μmol/L,with no single reading exceeding 600μmol/L;n=14)and poorly-controlled group(one or more phenylalanine readings above 600μmol/L during the follow-up period;n=25).Results The mean height readings for all time points(at birth and 3,6,9,12,15,18,21,24 and 36 months of age)were higher in the well-controlled group than the poorly-controlled group,however,only at 3 months of age the difference was statistically significant.Height Z-scores revealed a clearer pattern:although the poorly controlled group had higher height Z-scores at birth(P=0.001),the well-controlled group showed significantly higher height Z-scores at 3,6,12,15,18,24,and 36 months(P<0.05).The well-controlled group exhibited significantly higher mean weight measurements compared to the poorly-controlled group at 3,6,9,15,18 months and 21 months(P<0.05).From 6 to 36 months,the well-controlled group consistently had significantly higher weight Z-scores than the poorly controlled group(P<0.05).The well-controlled group showed more favorable height and weight Z-score distributions at 36 months of age compared to the poorly-controlled group,but the differences were not statistically significant(P>0.05).Both groups had height and weight Z-scores within the normal range at 36 months of age.Conclusions The children with phenylketonuria who receive good dietary control show better improvements in growth parameters compared to those with poor dietary control,however,both groups maintain height and weight Z-scores within the normal range,indicating generally adequate physical development across the cohort.
基金Supported by the National Natural Science Foundation of China,No.82105018 and No.81903950.
文摘BACKGROUND Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus(T2DM)among children and adolescents worldwide.Due to rapid disease progression,severe long-term cardiorenal complications,a lack of effective treatment strategies,and substantial socioeconomic burdens,it has become an urgent public health issue that requires management and resolution.Adolescent T2DM differs from adult T2DM.Despite a significant increase in our understanding of youth-onset T2DM over the past two decades,the related review and evidence-based content remain limited.AIM To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.METHODS This study utilized the terms“children”,“adolescents”,and“type 2 diabetes”,retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection(SCI,SSCI,ESCI).Utilizing CiteSpace and VoSviewer software,we analyze and visually represent the annual output of literature,countries involved,and participating institutions.This allows us to predict trends in this research field.Our analysis encompasses co-cited authors,journal overlays,citation overlays,time-zone views,keyword analysis,and reference analysis,etc.RESULTS A total of 9210 articles were included,and the annual publication volume in this field showed a steady growth trend.The United States had the highest number of publications and the highest H-index.The United States also had the most research institutions and the strongest research capacity.The global hot journals were primarily diabetes professional journals but also included journals related to nutrition,endocrinology,and metabolism.Keyword analysis showed that research related to endothelial dysfunction,exposure risk,cardiac metabolic risk,changes in gut microbiota,the impact on comorbidities and outcomes,etc.,were emerging keywords.They have maintained their popularity in this field,suggesting that these areas have garnered significant research interest in recent years.CONCLUSION Pediatric and adolescent T2DM is increasingly drawing global attention,with genes,behaviors,environmental factors,and multisystemic interventions potentially emerging as future research hot spots.
文摘Introduction: Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a sleep-related breathing disorder characterized by repeated episodes of partial obstruction of the upper airways (hypopnea) and/or intermittent complete obstruction (apnea). Our aim is to study the role of adeno-tonsillectomy in the management of OSAHS in children. Methodology: This was a prospective descriptive study conducted in the ENT-Head and Neck Surgery department of Ignace Deen National Hospital over a six-month period. We included in our study all patients aged 0 to 15 years, presenting with OSAHS of ENT etiology and who had undergone tonsillectomy/adenoidectomy. Results: The frequency of OSAHS was 13%. The mean age of our patients was 5.1 ± 3.8 years. There was a predominance of males (69.6%) with a sex ratio of 2.28. Snoring (98.6%), nasal obstruction (97.1%), and mouth breathing (96.6%) were the main reasons for consultation. Adeno-tonsillectomy (45.4%) was the primary surgical intervention. Almost all children (99.0%) had a simple postoperative course. Conclusion: OSAHS is a condition with a multifactorial etiology. Adeno-tonsillectomy remains the first-line surgical treatment to prevent severe complications and relieve the patient. Multidisciplinary collaboration is essential in the management of OSAHS.
文摘Domestic accidents (DA) are common in children and responsible for high morbidity and mortality in developed countries. Objective: This work aimed to describe the epidemiological profile of AD in children aged 0 to 15 years in Libreville. Materials and Methods: All children aged 0 to 15 years who were victims of unintentional trauma occurring at home or in its immediate surroundings were included. We studied the mother’s age, family situation, socioeconomic level, type of housing, age and sex of the child, characteristics of AD and their management. Results: The majority of mothers lived in an intermediate dwelling (80.6%). They were married (37.1%), middle managers (58.2%) and of average socioeconomic level (60.5%). The average age of the mothers was 39.9 ± 11.4 years. Families with more than three children were most exposed (39.2%) to the occurrence of AD. The average age of the children was 6.5 ± 3.3 years with a male predominance. The sex ratio was 1.8. The most common ADs were falls (34.7%), followed by cuts (22.3%) and burns (17.7%). Wounds (54.4%), followed by burns (33%) and fractures (5.1%) were the main types of injuries. The upper limbs were the most affected body part (33.9%) followed by the lower limbs (30.1%) and the head (27.3%). The yard was the preferred location for ADs to occur (51.1%), and particularly during the holiday period (48.4%). The risk factors related to the occurrence of AD were age, socioeconomic level, number of children and type of housing. Care was provided at home in 51.9% of cases. Conclusion: The occurrence of AD in children is not negligible;hence the need to implement preventive measures to minimize their frequency.
文摘BACKGROUND Unintended pregnancy occurs when an individual or couple conceives without planning or desire,which can potentially affect a child’s physical,mental,and social well-being.This can then lead to long-term socioeconomic challenges for families and communities.Although its impact on child growth and development is a pressing concern,research remains limited particularly in multicenter settings.AIM To examine the long-term consequences of unintended pregnancy on the critical years of early childhood growth and development.METHODS This analytical observational study employed a case-control design and was conducted in research centers across Indonesia,encompassing those located in Central Java,Lampung,Bali,and West Nusa Tenggara.A total of 700 children aged≤5 years with histories of intended or unintended pregnancies participated.Data collection involved structured interviews and direct anthropometric and developmental assessments.Data analyses were conducted using multivariate statistics and partial least squares structural equation modeling.RESULTS Unintended pregnancy was found to have a statistically significant effect on both child growth(t=8.178;P<0.001)and child development(t=25.688;P<0.001).Key growth problems identified included underweight,undernutrition,abnormal head circumference,and stunting.Developmental challenges prominently associated with unintended pregnancy included behavioral and emotional disorders,autism spectrum disorder,attentiondeficit/hyperactivity disorder,social and motor skill deficits,as well as visual and hearing impairments.CONCLUSION Unintended pregnancy significantly affects child growth and development,underscoring the need for early intervention,quality prenatal care,and strengthened family planning policies.
基金the Chiang Mai University Junior ResearchFellowship Program.
文摘Objective:Many children with fully corrected congenital heart disease(CHD)avoid physicalactivity(PA).This descriptive study sought to determine child and parental factors that could predict PAlevels in Thai dhildren after corrective surgery.Methods:Ninety schoolaged children with fully correctedCHD were recruited from a cardiology clinic at a university hospital in northern Thailand.Data collectioninvolved five validated questionnaires:(1)the Modified Thai Adolescent's Fhysical Activity Questionnaire,(2)the Child Health Status Questionnaire-Forms I and II1,(3)the Parental Knowledge on School-agedChildrer's PhysicalActivity Scale,(4)the Perceived Self-efficacy to Physical Activity Questionnaire,and(5)the Parntal Bonding Instrument.The analysis included descriptive statistics and stepwise multipleregression.Results:Results showed that the physical activity(PA.)levels,assessed through total energyexpenditure,of child ran with CHD were below the recommended levels after treatment(t=-8.33,p<0.001).There were sigrificant correlations between PA and factors such as a child's perceived health status,PAself-efficacy,and parentaloverprotection(r=0.39,p<0.050;r=0.46,p<0.050;r=0.25,p<0.050,respectively).After adjustment for demographic data and CHD type,these factors had no association with a child's PA.Only two factors predicted childhood PA—the child's perceived health status and PA self-efficacy whichcould explain27.3%of the variance of PA.(p<0.001).Conclusion:The study highlights the necessity forinterventions to enhance childrer's perception of their health status and PA self-efficacy to increase theirphysical activity levels.
基金This study received a research grant from the Hoyu Science Foundation in 2023.
文摘We investigated the psychological effects of nail treatments on children living in child welfare facilities.We performed a single nail treatment on children living in child welfare facilities.As a result,we found that feelings of“energy”,“relaxation”,and“comfort”tended to increase more strongly after the treatment than before.Furthermore,these feelings increased even more after the nail treatment.The effects of nail treatments were unrelated to gender or previous nail experience.Furthermore,nail treatments increased communication and interaction with facility staff and other children residing in the facility,promoting self-expression,and,as a result,increasing a sense of accomplishment,acceptance from others,and self-esteem.This suggests that positive emotions persisted even after nail treatments,leading to positive changes in daily life.
文摘The usage characteristics of the large numerals in child language reflects both linguistic and cognitive development.The present study systematically examined Mandarin children’s naturalistic use of large numerals“bai”,“qian”,and“wan”and compared it with adult usage patterns based on a self-constructed corpus.The results revealed a significant preference for the use of“bai”over both“qian”and“wan”among children and adults alike.This shared pattern suggests that children’s acquisition of large numerals is strongly shaped by adult language input.This study addresses a critical gap in research on the acquisition of large numerals by Mandarin-speaking children,providing valuable insights for the broader theoretical framework of cross-linguistic numerical cognition.
文摘BACKGROUND Oral food challenge(OFC)is an integral part of confirming and evaluating the diagnosis of food allergy(FA),and most incidents of FA occur in children.FA significantly impairs the quality of life(QoL)and causes limited activities outside the home for children and their parents.AIM To evaluate the effect of OFC on QoL and family activities in children with FA.METHODS This prospective study identified children suspected of FA using a skin prick test(SPT)between January 2022 and December 2024.These children conduct an elimination diet for 4 wk,followed by OFC under protocol.Rating scales eva-luated QoL using pediatric QoL inventory and family activities using family ac-tivities impact scale(FAIS),in which data are collected before and after an elimination diet and OFC.Statistical analysis utilized χ^(2),Spearman,paired t,Wilcoxon,independent t,and Mann–Whitney tests,with P<0.05 considered significant.RESULTS Most participants were boys(137;65.55%);102(64.56%)had a positive OFC and 92.40±4.22 after OFC(Z=12.537;P<0.001).In the FAIS score,the average result before OFC was 5.36±0.68 and 4.10±0.38 after OFC,which was a significant difference(Z=12.162;P<0.001).Although the difference in QoL before and after increased,and FAIS reduced,there was no significant difference.Additionally,most results of positive SPT are higher than positive OFC in each specific food allergen.CONCLUSION OFC may improve QoL and FAIS in children with FA and their families as it increases activities outside the home and reduces worry about allergen exposure.
基金funded by a Grant-in-Aid for Scientific Research(JP19K19762,JP 23K10258)from the Japan Society for the Promotion of Science,Japan.
文摘Objectives:To evaluate the occurrence of depression and its related factors among public health nurses(PHNs)engaged in child neglect-related abuse cases.Methods:A cross-sectional study of PHNs involved in maternal and child health or child and family welfare,and engaged in cases of child neglect-related abuse was conducted from January to March 2023 in all municipalities of 13 prefectures selected from Japan's seven regions,considering geographic diversity and major urban areas.The Patient Health Questionnaire-2 was used to screen for depression.Statistical analyses included the Chi-square test,Mann-Whitney U test,and logistic regression analysis.Results:A total of 359 provided valid responses.Among them,11.4%screened positive for depression.Significant individual factors related depression were management-stage nurses(OR=6.27,95%CI:1.63-24.18),no disability welfare experience(OR=3.49,95%CI:1.05-11.55),being assignment of highrisk cases within the past year(OR=8.28,95%CI:2.07-33.08),and lower work control(OR=0.53,95%CI:0.32-0.86).Workplace environment factors were lower perceptions and relationships within the workplace(OR=0.43,95%CI:0.29-0.65)and perceiving manpower as not secured(OR=9.07,95%CI:1.17-70.40),Conclusions:Mental health measures for PHNs should include workload management and reduced burdens through workforce enhancement,attention to burdens on managerial PHNs,promoting communication and mutual support,and opportunities to engage in disability welfare work.
文摘With the widespread adoption of smartphones,parental phubbing behaviors have become increasingly prevalent,potentially affecting preschool children’s development.Current research primarily focuses on adolescent populations,while the mechanisms through which parental phubbing and authoritarian parenting style influence preschool children’s behavioral problems within the Chinese cultural context remain to be explored.Our investigation seeks to examine the factors contributing to behavioral difficulties among children of preschool age and provide theoretical guidance for prevention.Methods In our research,we utilized a convenience sampling approach to collect data from parents whose children(n=612)were between 3 and 7 years of age.The questionnaire distribution was facilitated via the Wenjuanxing online survey platform.Research instruments included the Parental Phubbing Scale,Parent-Child Relationship Scale,Authoritarian Parenting Style Scale,and Conners Child Behavior Rating Scale.For analytical procedures,we employed SPSS 24.0 to generate descriptive statistics and correlation analysis.Chain mediation effects were examined via Process macro,while significance assessment of the mediating effects relied on the Bootstrap method for constructing 95%confidence intervals.Results A statistically significant positive association was observed between parental phubbing and behavioral problems exhibited by children(r=0.251,p<0.001).Parental phubbing exhibited a significant direct effect on children’s behavioral problems(β=0.088,p<0.001).Analysis of sequential mediation demonstrated that authoritarian parenting style together with parent-child conflict functioned as significant intermediary variables in the relationship between parental phubbing and children’s problem behaviors(β=0.163,p<0.001),with these indirect pathways constituting 64.94%of the total effect.Conclusion Parental phubbing significantly contributes to behavioral problems in preschool children.Parents should monitor their media use,improve their parenting approach,and enhance parent-child relationships to reduce behavioral problems in preschool children.
基金Supported by General Projects of Henan Province Universities Humanities and Social Sciences Research in 2023,No.2023-ZDJH-533.
文摘BACKGROUND China has recently encountered severe challenges associated with population aging.Parents of first-generation only children face significant challenges regarding elderly care needs and the associated negative emotions.AIM To analyze the elderly care needs of first-generation only child parents in China and identify factors that influence negative emotions.METHODS This study used a cross-sectional design.Convenience sampling was used to select 1580 elderly individuals who met the inclusion criteria in a Chinese city between June and September 2022.A questionnaire was administered to collect general information about participants.Depression and anxiety were assessed using the patient health questionnaire-9 and generalized anxiety disorder-7 scale,respectively.A logistic regression analysis was performed to evaluate the relevant correlations.RESULTS Among 1580 first-generation only child parents,1120(70.89%)preferred family based care,324(20.51%)opted for community care,and 136(8.61%)chose institutional care,with 460(29.11%)reporting negative emotions.Significant differences in the distribution of negative emotions among only child parents were observed based on age,marital status,living conditions,disability,type of chronic disease,frailty status,and family support(P<0.05).The regression analysis indicated that disability,type of chronic disease,living environment,frailty status,and level of family support were independent risk factors for negative emotions among parents with only children(P<0.05).CONCLUSION Elderly care for parents of only children is primarily family-based.Independent risk factors for negative emotions in this group include disability,chronic disease type,and living environment.
文摘Objective:To explore the impact of parenting care guidance combined with preventive healthcare on child family parenting.Methods:Ninety-two child families were included as research subjects and randomly divided into a control group and an observation group,with 46 cases in each group.The former implemented basic preventive healthcare,while the latter simultaneously carried out parenting care guidance combined with preventive healthcare.The intervention results of the two groups were compared.Results:The observation group had a higher awareness rate of family parenting knowledge and a higher formation rate of healthy behaviors,P<0.05.At the same time,parents’parenting anxiety scores were lower,and family health management ability scores were higher,P<0.05.Moreover,the observation group showed higher scores in children’s social skills,P<0.05.Conclusion:Parenting care guidance combined with preventive healthcare can effectively improve the status of child family parenting,and it is worthy of promotion and application.
