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Monaco计划系统Multicriterial功能在肺癌动态调强计划设计中的应用
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作者 曹婧 郑倩倩 +2 位作者 高文超 曲荣荣 王子红 《医疗装备》 2025年第14期1-4,11,共5页
目的探究Monaco计划系统Multicriterial功能对肺癌动态调强计划设计中靶区及危及器官(OAR)受照射剂量的影响。方法回顾性选取2020年9月至2023年7月医院收治的20例肺癌患者资料,分别设计两种放疗方案进行比对,其中dIMRTNM计划组采用常规... 目的探究Monaco计划系统Multicriterial功能对肺癌动态调强计划设计中靶区及危及器官(OAR)受照射剂量的影响。方法回顾性选取2020年9月至2023年7月医院收治的20例肺癌患者资料,分别设计两种放疗方案进行比对,其中dIMRTNM计划组采用常规设计,dIMRTM计划组采用Multicritecial功能设计,两组其他计划参数均一致,比较两组计划的靶区剂量参数[适形性指数(CI)、均匀性指数(HI)]、OAR的受照射剂量、治疗时间[采用机器跳数(MU)评估]。结果两组计划结果均能满足临床要求,dIMRTM计划HI值大于dIMRTNM计划,CI值小于dIMRTNM计划(P<0.05)。dIMRTM计划的患侧肺V_(5)、V_(20)、D_(mean),健侧肺D_(mean)及双肺V_(20)、V_(30)、D_(mean)均低于dIMRTNM计划(P<0.05)。两组计划的心脏、食管、气管、脊髓受照射剂量及MU比较,差异无统计学意义(P>0.05)。结论在肺癌患者dIMRT计划设计中,Multicriterial功能可以降低目标OAR的受照射剂量,且不会延长治疗时间,但靶区的CI和HI会略微变差。 展开更多
关键词 肺癌 Monaco计划系统 Multicriterial功能 动态调强放射治疗
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Monaco计划系统Multicriterial功能在乳腺癌改良根治术后计划设计中的应用 被引量:3
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作者 郑倩倩 高文超 +3 位作者 曹婧 曲荣荣 王丹鹤 陈文彰 《生物医学工程与临床》 CAS 2023年第1期66-69,共4页
目的探讨Monaco计划系统中Multicriterial功能在乳腺癌改良根治术后计划设计中对靶区和危及器官受照剂量的影响。方法选择乳腺癌根治术后接受放射治疗患者20例,年龄36~80岁,中位年龄59岁;肿瘤单一病灶17例,多个病灶3例;肿瘤直径<2 cm... 目的探讨Monaco计划系统中Multicriterial功能在乳腺癌改良根治术后计划设计中对靶区和危及器官受照剂量的影响。方法选择乳腺癌根治术后接受放射治疗患者20例,年龄36~80岁,中位年龄59岁;肿瘤单一病灶17例,多个病灶3例;肿瘤直径<2 cm的7例,2~5 cm 13例;TNM分期Ⅱ期8例,Ⅲ期12例。基于Monaco计划系统5.51为每例患者制定两种调强放疗(IMRT)计划,其中一种应用了Monaco计划系统中优化过程中Multicriterial功能(IMRTM),第二种复制第一种计划并在优化过程中去除Multicriterial功能(IMRTNM)重新优化并计算结果。比较两种计划的剂量参数,靶区的适形性指数(CI)、均匀性指数(HI)、平均剂量、最大剂量;肺、心脏、健侧乳腺和脊髓等危及器官的受照剂量差异。结果两种计划靶区参数均能满足临床需求,IMRTNM计划略优于IMRTM计划,其中在胸壁区(PTV1)和锁骨上区(PTV2)的最大值(D_(max))参数上,IMRTNM计划均优于IMRTM计划,且差异均有统计学意义[(5573.54±71.58)cGy vs(5617.02±64.25)c Gy、(5491.56±67.14)cGy vs(5636.35±64.13)cGy。P<0.05];对于危及器官,IMRTM计划除了脊髓以外,在患侧肺V5、V20及V30、健侧肺V5、心脏D_(mean)、健侧乳腺D_(mean)受照剂量保护方面均优于IMRTNM计划,且差异均有统计学意义[(47.18±4.57)%vs(49.68±4.61)%、(26.98±4.29)%vs(29.46±4.33)%、(21.51±3.80)%vs(23.63±4.00)%。P<0.05]、[(16.82±16.00)%vs(17.19±16.34)%。P<0.05]、[(518.87±402.22)cGy vs(561.83±425.00)cGy。P<0.05]、[(501.84±291.17)cGy vs(541.96±297.54)cGy。P<0.05]。结论Monaco计划系统的Multicriterial功能在乳腺癌改良根治术后放射治疗计划设计中,不仅能够满足靶区临床需求,还可以有效地降低肺、健侧乳腺、心脏等危及器官的受照剂量。 展开更多
关键词 乳腺癌 Monaco计划系统 Multicriterial功能 剂量参数
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Application of Fuzzy Optimization Method in Decision-Making for Personnel Selection
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作者 Masuma Mammadova Zarifa Jabrayilova 《Intelligent Control and Automation》 2014年第4期190-204,共15页
The paper describes the necessity of application of intelligent technologies to support decisions of more objective problems in human resource management. In this paper, we describe the methodology for personnel selec... The paper describes the necessity of application of intelligent technologies to support decisions of more objective problems in human resource management. In this paper, we describe the methodology for personnel selection problem for the vacancy with regard to the importance and nonequivalence of numerous indicators characterizing the alternatives. The specific features of the selection problem are highlighted, immersing the problem into a fuzzy environment. A fuzzy multicriterial model of the personnel selection problem is proposed. A technique of order preference by similarity to ideal solition (TOPSIS), was applied for evaluation and regulation of alternatives. This technique is based on criteria of qualitative character, which are hierarchically structured by multiple experts to intellectually support decisions made in personnel selection problem. Using TOPSIS method and generated criteria system an experiment was conducted for evaluation of the candidates during solution of hiring problems. The obtained and reviewed results were compared with results obtained using in reality. 展开更多
关键词 Support Decision Human Resource Management PERSONNEL Selection Problem FUZZY Multicriterial Model Criteria COEFFICIENTS FUZZY Number TOPSIS METHOD
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Multicriteria Analysis of a Capacity Expansion Problem:Damaturu, Northeastern Nigeria as Case Study
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作者 Mallam Zaji Bunuq(Hohai University, Foreign Students’ Building Room 307, Nanjing, 210095, P. R. China.) 《Systems Science and Systems Engineering》 CSCD 1999年第1期112-118,共7页
Damaturu, the Yobe State Capital is one of the major towns in the semi-arid areas OfNortheastern Nigeria. It lacks adequate water supply. Being a State Capital, rapid improvements in itsinfrastructures including wate... Damaturu, the Yobe State Capital is one of the major towns in the semi-arid areas OfNortheastern Nigeria. It lacks adequate water supply. Being a State Capital, rapid improvements in itsinfrastructures including water supply to cope with increased demands are required. Three options forthe expansion of the present water supply system are been considered. These are Groundwater resourceswithin and around the existing system, and surface water schemes from two Dam sites identitied andappraised for this purpose. The Management of the Yobe State Water Board and the State Governmentare faced with the problem of which of these three options to choose. This is a typical capacity expansionproblem within a multicriterion setting in which the choice is to be bassed on economic, environmental,social as well as political considerstions. This paper presents a multicriterion analysis whose result willbe used in forming the basis of an informed decision to be made on why a particular option is to bechosen. 展开更多
关键词 Damaturu Capacity expansion multicriteris analysis Ranking.
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