The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect...The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than 50million people worldwide.Neurodegenerative disorders are characterized by sundry factors and pathophysiological mechanisms that a re challenging to be fully profiled.Many of these rely on cell signaling pathways to preserve homeostasis,involving second messengers such as cyclic adenosine monophosphate (cAMP)and cyclic guanosine 3',5'-monophosphate(cGMP).Their ability to control the duration and amplitude of the signaling cascade is given by the presence of several common and uncommon effectors.Protein kinases A and G (PKA and PKG),phosphodiesterases (PDEs),and scaffold proteins are among them.展开更多
The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years...The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years,from traditional manufacturing giants to emerging tech unicorns,and from traditional sectors to emerging industries like electric vehicles,lithium batteries,and photovoltaic products.The enthusiasm to internationalize reached unprecedented levels in 2024.展开更多
Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civili...Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civilizations,where ideas and cultures have exchanged and thrived.Driven by the vision of a community with a shared future for mankind in recent years,Chengdu scholars and media have opened their arms to the world,engaging in multilingual storytelling.These efforts share the warmth and goodwill of a city consistently ranked one of the happiest in China.Through consistent efforts,new insights have emerged—ideas and aspirations intended to be shared with readers both at home and abroad.展开更多
As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial c...As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial control system of the gas extraction plant is characterized by numerous points and centralized operations,with a strong reliance on the system and stringent real-time requirements.展开更多
文摘The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than 50million people worldwide.Neurodegenerative disorders are characterized by sundry factors and pathophysiological mechanisms that a re challenging to be fully profiled.Many of these rely on cell signaling pathways to preserve homeostasis,involving second messengers such as cyclic adenosine monophosphate (cAMP)and cyclic guanosine 3',5'-monophosphate(cGMP).Their ability to control the duration and amplitude of the signaling cascade is given by the presence of several common and uncommon effectors.Protein kinases A and G (PKA and PKG),phosphodiesterases (PDEs),and scaffold proteins are among them.
文摘The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years,from traditional manufacturing giants to emerging tech unicorns,and from traditional sectors to emerging industries like electric vehicles,lithium batteries,and photovoltaic products.The enthusiasm to internationalize reached unprecedented levels in 2024.
文摘Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civilizations,where ideas and cultures have exchanged and thrived.Driven by the vision of a community with a shared future for mankind in recent years,Chengdu scholars and media have opened their arms to the world,engaging in multilingual storytelling.These efforts share the warmth and goodwill of a city consistently ranked one of the happiest in China.Through consistent efforts,new insights have emerged—ideas and aspirations intended to be shared with readers both at home and abroad.
文摘As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial control system of the gas extraction plant is characterized by numerous points and centralized operations,with a strong reliance on the system and stringent real-time requirements.