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Synaptic pruning mechanisms and application of emerging imaging techniques in neurological disorders
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作者 Yakang Xing Yi Mo +1 位作者 Qihui Chen Xiao Li 《Neural Regeneration Research》 2026年第5期1698-1714,共17页
Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience... Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience-dependent mechanisms.The pruning process involves multiple molecular signals and a series of regulatory activities governing the“eat me”and“don't eat me”states.Under physiological conditions,the interaction between glial cells and neurons results in the clearance of unnecessary synapses,maintaining normal neural circuit functionality via synaptic pruning.Alterations in genetic and environmental factors can lead to imbalanced synaptic pruning,thus promoting the occurrence and development of autism spectrum disorder,schizophrenia,Alzheimer's disease,and other neurological disorders.In this review,we investigated the molecular mechanisms responsible for synaptic pruning during neural development.We focus on how synaptic pruning can regulate neural circuits and its association with neurological disorders.Furthermore,we discuss the application of emerging optical and imaging technologies to observe synaptic structure and function,as well as their potential for clinical translation.Our aim was to enhance our understanding of synaptic pruning during neural development,including the molecular basis underlying the regulation of synaptic function and the dynamic changes in synaptic density,and to investigate the potential role of these mechanisms in the pathophysiology of neurological diseases,thus providing a theoretical foundation for the treatment of neurological disorders. 展开更多
关键词 CHEMOKINE COMPLEMENT experience-dependent driven synaptic pruning imaging techniques NEUROGLIA signaling pathways synapse elimination synaptic pruning
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Modeling Pruning as a Phase Transition:A Thermodynamic Analysis of Neural Activations
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作者 Rayeesa Mehmood Sergei Koltcov +1 位作者 Anton Surkov Vera Ignatenko 《Computers, Materials & Continua》 2026年第3期2304-2327,共24页
Activation pruning reduces neural network complexity by eliminating low-importance neuron activations,yet identifying the critical pruning threshold—beyond which accuracy rapidly deteriorates—remains computationally... Activation pruning reduces neural network complexity by eliminating low-importance neuron activations,yet identifying the critical pruning threshold—beyond which accuracy rapidly deteriorates—remains computationally expensive and typically requires exhaustive search.We introduce a thermodynamics-inspired framework that treats activation distributions as energy-filtered physical systems and employs the free energy of activations as a principled evaluation metric.Phase-transition-like phenomena in the free-energy profile—such as extrema,inflection points,and curvature changes—yield reliable estimates of the critical pruning threshold,providing a theoretically grounded means of predicting sharp accuracy degradation.To further enhance efficiency,we propose a renormalized free energy technique that approximates full-evaluation free energy using only the activation distribution of the unpruned network.This eliminates repeated forward passes,dramatically reducing computational overhead and achieving speedups of up to 550×for MLPs.Extensive experiments across diverse vision architectures(MLP,CNN,ResNet,MobileNet,Vision Transformer)and text models(LSTM,BERT,ELECTRA,T5,GPT-2)on multiple datasets validate the generality,robustness,and computational efficiency of our approach.Overall,this work establishes a theoretically grounded and practically effective framework for activation pruning,bridging the gap between analytical understanding and efficient deployment of sparse neural networks. 展开更多
关键词 THERMODYNAMICS activation pruning model compression SPARSITY free energy RENORMALIZATION
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Impact toughness,crack initiation and propagation mechanism of Ti6422 alloy with multi-level lamellar microstructure
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作者 Jie Shen Zhihao Zhang Jianxin Xie 《International Journal of Minerals,Metallurgy and Materials》 2026年第2期595-609,共15页
The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.... The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation. 展开更多
关键词 novel titanium alloy multi-level lamellar microstructure impact toughness crack initiation and propagation
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Mitigating Attribute Inference in Split Learning via Channel Pruning and Adversarial Training
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作者 Afnan Alhindi Saad Al-Ahmadi Mohamed Maher Ben Ismail 《Computers, Materials & Continua》 2026年第3期1465-1489,共25页
Split Learning(SL)has been promoted as a promising collaborative machine learning technique designed to address data privacy and resource efficiency.Specifically,neural networks are divided into client and server subn... Split Learning(SL)has been promoted as a promising collaborative machine learning technique designed to address data privacy and resource efficiency.Specifically,neural networks are divided into client and server subnetworks in order to mitigate the exposure of sensitive data and reduce the overhead on client devices,thereby making SL particularly suitable for resource-constrained devices.Although SL prevents the direct transmission of raw data,it does not alleviate entirely the risk of privacy breaches.In fact,the data intermediately transmitted to the server sub-model may include patterns or information that could reveal sensitive data.Moreover,achieving a balance between model utility and data privacy has emerged as a challenging problem.In this article,we propose a novel defense approach that combines:(i)Adversarial learning,and(ii)Network channel pruning.In particular,the proposed adversarial learning approach is specifically designed to reduce the risk of private data exposure while maintaining high performance for the utility task.On the other hand,the suggested channel pruning enables the model to adaptively adjust and reactivate pruned channels while conducting adversarial training.The integration of these two techniques reduces the informativeness of the intermediate data transmitted by the client sub-model,thereby enhancing its robustness against attribute inference attacks without adding significant computational overhead,making it wellsuited for IoT devices,mobile platforms,and Internet of Vehicles(IoV)scenarios.The proposed defense approach was evaluated using EfficientNet-B0,a widely adopted compact model,along with three benchmark datasets.The obtained results showcased its superior defense capability against attribute inference attacks compared to existing state-of-the-art methods.This research’s findings demonstrated the effectiveness of the proposed channel pruning-based adversarial training approach in achieving the intended compromise between utility and privacy within SL frameworks.In fact,the classification accuracy attained by the attackers witnessed a drastic decrease of 70%. 展开更多
关键词 Split learning privacy-preserving split learning distributed collaborative machine learning channel pruning adversarial learning resource-constrained devices
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SFPBL:Soft Filter Pruning Based on Logistic Growth Differential Equation for Neural Network 被引量:1
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作者 Can Hu Shanqing Zhang +2 位作者 Kewei Tao Gaoming Yang Li Li 《Computers, Materials & Continua》 2025年第3期4913-4930,共18页
The surge of large-scale models in recent years has led to breakthroughs in numerous fields,but it has also introduced higher computational costs and more complex network architectures.These increasingly large and int... The surge of large-scale models in recent years has led to breakthroughs in numerous fields,but it has also introduced higher computational costs and more complex network architectures.These increasingly large and intricate networks pose challenges for deployment and execution while also exacerbating the issue of network over-parameterization.To address this issue,various network compression techniques have been developed,such as network pruning.A typical pruning algorithm follows a three-step pipeline involving training,pruning,and retraining.Existing methods often directly set the pruned filters to zero during retraining,significantly reducing the parameter space.However,this direct pruning strategy frequently results in irreversible information loss.In the early stages of training,a network still contains much uncertainty,and evaluating filter importance may not be sufficiently rigorous.To manage the pruning process effectively,this paper proposes a flexible neural network pruning algorithm based on the logistic growth differential equation,considering the characteristics of network training.Unlike other pruning algorithms that directly reduce filter weights,this algorithm introduces a three-stage adaptive weight decay strategy inspired by the logistic growth differential equation.It employs a gentle decay rate in the initial training stage,a rapid decay rate during the intermediate stage,and a slower decay rate in the network convergence stage.Additionally,the decay rate is adjusted adaptively based on the filter weights at each stage.By controlling the adaptive decay rate at each stage,the pruning of neural network filters can be effectively managed.In experiments conducted on the CIFAR-10 and ILSVRC-2012 datasets,the pruning of neural networks significantly reduces the floating-point operations while maintaining the same pruning rate.Specifically,when implementing a 30%pruning rate on the ResNet-110 network,the pruned neural network not only decreases floating-point operations by 40.8%but also enhances the classification accuracy by 0.49%compared to the original network. 展开更多
关键词 Filter pruning channel pruning CNN complexity deep neural networks filtering theory logistic model
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A Multi-Level Semantic Constraint Approach for Highway Tunnel Scene Twin Modeling 被引量:2
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作者 LI Yufei XIE Yakun +3 位作者 CHEN Mingzhen ZHAO Yaoji TU Jiaxing HU Ya 《Journal of Geodesy and Geoinformation Science》 2025年第2期37-56,共20页
As a key node of modern transportation network,the informationization management of road tunnels is crucial to ensure the operation safety and traffic efficiency.However,the existing tunnel vehicle modeling methods ge... As a key node of modern transportation network,the informationization management of road tunnels is crucial to ensure the operation safety and traffic efficiency.However,the existing tunnel vehicle modeling methods generally have problems such as insufficient 3D scene description capability and low dynamic update efficiency,which are difficult to meet the demand of real-time accurate management.For this reason,this paper proposes a vehicle twin modeling method for road tunnels.This approach starts from the actual management needs,and supports multi-level dynamic modeling from vehicle type,size to color by constructing a vehicle model library that can be flexibly invoked;at the same time,semantic constraint rules with geometric layout,behavioral attributes,and spatial relationships are designed to ensure that the virtual model matches with the real model with a high degree of similarity;ultimately,the prototype system is constructed and the case region is selected for the case study,and the dynamic vehicle status in the tunnel is realized by integrating real-time monitoring data with semantic constraints for precise virtual-real mapping.Finally,the prototype system is constructed and case experiments are conducted in selected case areas,which are combined with real-time monitoring data to realize dynamic updating and three-dimensional visualization of vehicle states in tunnels.The experiments show that the proposed method can run smoothly with an average rendering efficiency of 17.70 ms while guaranteeing the modeling accuracy(composite similarity of 0.867),which significantly improves the real-time and intuitive tunnel management.The research results provide reliable technical support for intelligent operation and emergency response of road tunnels,and offer new ideas for digital twin modeling of complex scenes. 展开更多
关键词 highway tunnel twin modeling multi-level semantic constraints tunnel vehicles multidimensional modeling
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Research on Multi-Level Automatic Filling Optimization Design Method for Layered Cross-Sectional Layout of Umbilical 被引量:1
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作者 YIN Xu FAN Zhi-rui +4 位作者 CAO Dong-hui LIU Yu-jie LI Meng-shu YAN Jun YANG Zhi-xun 《China Ocean Engineering》 2025年第5期891-903,共13页
The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly comple... The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections. 展开更多
关键词 UMBILICAL cross-sectional layout multi-level filling layered layout optimization design
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Hierarchical Shape Pruning for 3D Sparse Convolution Networks
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作者 Haiyan Long Chonghao Zhang +2 位作者 Xudong Qiu Hai Chen Gang Chen 《Computers, Materials & Continua》 2025年第8期2975-2988,共14页
3D sparse convolution has emerged as a pivotal technique for efficient voxel-based perception in autonomous systems,enabling selective feature extraction from non-empty voxels while suppressing computational waste.Des... 3D sparse convolution has emerged as a pivotal technique for efficient voxel-based perception in autonomous systems,enabling selective feature extraction from non-empty voxels while suppressing computational waste.Despite its theoretical efficiency advantages,practical implementations face under-explored limitations:the fixed geometric patterns of conventional sparse convolutional kernels inevitably process non-contributory positions during sliding-window operations,particularly in regions with uneven point cloud density.To address this,we propose Hierarchical Shape Pruning for 3D Sparse Convolution(HSP-S),which dynamically eliminates redundant kernel stripes through layer-adaptive thresholding.Unlike static soft pruning methods,HSP-S maintains trainable sparsity patterns by progressively adjusting pruning thresholds during optimization,enlarging original parameter search space while removing redundant operations.Extensive experiments validate effectiveness of HSP-S acrossmajor autonomous driving benchmarks.On KITTI’s 3D object detection task,our method reduces 93.47%redundant kernel computations whilemaintaining comparable accuracy(1.56%mAP drop).Remarkably,on themore complexNuScenes benchmark,HSP-S achieves simultaneous computation reduction(21.94%sparsity)and accuracy gains(1.02%mAP(mean Average Precision)and 0.47%NDS(nuScenes detection score)improvement),demonstrating its scalability to diverse perception scenarios.This work establishes the first learnable shape pruning framework that simultaneously enhances computational efficiency and preserves detection accuracy in 3D perception systems. 展开更多
关键词 Shape pruning model compressing 3D sparse convolution
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Computation graph pruning based on critical path retention in evolvable networks
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作者 XIE Xiaoyan YANG Tianjiao +4 位作者 ZHU Yun LUO Xing JIN Luochen YU Jinhao REN Xun 《High Technology Letters》 2025年第3期266-272,共7页
The dynamic routing mechanism in evolvable networks enables adaptive reconfiguration of topol-ogical structures and transmission pathways based on real-time task requirements and data character-istics.However,the heig... The dynamic routing mechanism in evolvable networks enables adaptive reconfiguration of topol-ogical structures and transmission pathways based on real-time task requirements and data character-istics.However,the heightened architectural complexity and expanded parameter dimensionality in evolvable networks present significant implementation challenges when deployed in resource-con-strained environments.Due to the critical paths ignored,traditional pruning strategies cannot get a desired trade-off between accuracy and efficiency.For this reason,a critical path retention pruning(CPRP)method is proposed.By deeply traversing the computational graph,the dependency rela-tionship among nodes is derived.Then the nodes are grouped and sorted according to their contribu-tion value.The redundant operations are removed as much as possible while ensuring that the criti-cal path is not affected.As a result,computational efficiency is improved while a higher accuracy is maintained.On the CIFAR benchmark,the experimental results demonstrate that CPRP-induced pruning incurs accuracy degradation below 4.00%,while outperforming traditional feature-agnostic grouping methods by an average 8.98%accuracy improvement.Simultaneously,the pruned model attains a 2.41 times inference acceleration while achieving 48.92%parameter compression and 53.40%floating-point operations(FLOPs)reduction. 展开更多
关键词 evolvable network computation graph traversing dynamic routing critical path retention pruning
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Optimizing BERT for Bengali Emotion Classification: Evaluating Knowledge Distillation, Pruning, and Quantization
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作者 Md Hasibur Rahman Mohammed Arif Uddin +1 位作者 Zinnat Fowzia Ria Rashedur M.Rahman 《Computer Modeling in Engineering & Sciences》 2025年第2期1637-1666,共30页
The rapid growth of digital data necessitates advanced natural language processing(NLP)models like BERT(Bidi-rectional Encoder Representations from Transformers),known for its superior performance in text classificati... The rapid growth of digital data necessitates advanced natural language processing(NLP)models like BERT(Bidi-rectional Encoder Representations from Transformers),known for its superior performance in text classification.However,BERT’s size and computational demands limit its practicality,especially in resource-constrained settings.This research compresses the BERT base model for Bengali emotion classification through knowledge distillation(KD),pruning,and quantization techniques.Despite Bengali being the sixth most spoken language globally,NLP research in this area is limited.Our approach addresses this gap by creating an efficient BERT-based model for Bengali text.We have explored 20 combinations for KD,quantization,and pruning,resulting in improved speedup,fewer parameters,and reduced memory size.Our best results demonstrate significant improvements in both speed and efficiency.For instance,in the case of mBERT,we achieved a 3.87×speedup and 4×compression ratio with a combination of Distil+Prune+Quant that reduced parameters from 178 to 46 M,while the memory size decreased from 711 to 178 MB.These results offer scalable solutions for NLP tasks in various languages and advance the field of model compression,making these models suitable for real-world applications in resource-limited environments. 展开更多
关键词 Bengali NLP black-box distillation emotion classification model compression post-training quantization unstructured pruning
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CLAD:Criterion learner and attention distillation for automated CNN pruning
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作者 Zheng Li Jiaxin Li +2 位作者 Shaojie Liu Bo Zhao Derong Liu 《Journal of Automation and Intelligence》 2025年第4期254-265,共12页
Filter pruning effectively compresses the neural network by reducing both its parameters and computational cost.Existing pruning methods typically rely on pre-designed pruning criteria to measure filter importance and... Filter pruning effectively compresses the neural network by reducing both its parameters and computational cost.Existing pruning methods typically rely on pre-designed pruning criteria to measure filter importance and remove those deemed unimportant.However,different layers of the neural network exhibit varying filter distributions,making it inappropriate to implement the same pruning criterion for all layers.Additionally,some approaches apply different criteria from the set of pre-defined pruning rules for different layers,but the limited space leads to the difficulty of covering all layers.If criteria for all layers are manually designed,it is costly and difficult to generalize to other networks.To solve this problem,we present a novel neural network pruning method based on the Criterion Learner and Attention Distillation(CLAD).Specifically,CLAD develops a differentiable criterion learner,which is integrated into each layer of the network.The learner can automatically learn the appropriate pruning criterion according to the filter parameters of each layer,thus the requirement of manual design is eliminated.Furthermore,the criterion learner is trained end-to-end by the gradient optimization algorithm to achieve efficient pruning.In addition,attention distillation,which fully utilizes the knowledge of unpruned networks to guide the optimization of the learner and improve the pruned network performance,is introduced in the process of learner optimization.Experiments conducted on various datasets and networks demonstrate the effectiveness of the proposed method.Notably,CLAD reduces the FLOPs of Res Net-110 by about 53%on the CIFAR-10 dataset,while simultaneously improves the network's accuracy by 0.05%.Moreover,it reduces the FLOPs of Res Net-50 by about 46%on the Image Net-1K dataset,and maintains a top-1 accuracy of 75.45%. 展开更多
关键词 Neural network pruning Model compression Knowledge distillation Feature attention Polar regularization
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Greedy Pruning Algorithm for DETR Architecture Networks Based on Global Optimization
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作者 HUANG Qiubo XU Jingsai +2 位作者 ZHANG Yakui WANG Mei CHEN Dehua 《Journal of Donghua University(English Edition)》 2025年第1期96-105,共10页
End-to-end object detection Transformer(DETR)successfully established the paradigm of the Transformer architecture in the field of object detection.Its end-to-end detection process and the idea of set prediction have ... End-to-end object detection Transformer(DETR)successfully established the paradigm of the Transformer architecture in the field of object detection.Its end-to-end detection process and the idea of set prediction have become one of the hottest network architectures in recent years.There has been an abundance of work improving upon DETR.However,DETR and its variants require a substantial amount of memory resources and computational costs,and the vast number of parameters in these networks is unfavorable for model deployment.To address this issue,a greedy pruning(GP)algorithm is proposed,applied to a variant denoising-DETR(DN-DETR),which can eliminate redundant parameters in the Transformer architecture of DN-DETR.Considering the different roles of the multi-head attention(MHA)module and the feed-forward network(FFN)module in the Transformer architecture,a modular greedy pruning(MGP)algorithm is proposed.This algorithm separates the two modules and applies their respective optimal strategies and parameters.The effectiveness of the proposed algorithm is validated on the COCO 2017 dataset.The model obtained through the MGP algorithm reduces the parameters by 49%and the number of floating point operations(FLOPs)by 44%compared to the Transformer architecture of DN-DETR.At the same time,the mean average precision(mAP)of the model increases from 44.1%to 45.3%. 展开更多
关键词 model pruning object detection Transformer(DETR) Transformer architecture object detection
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Multi-relation spatiotemporal graph residual network model with multi-level feature attention:A novel approach for landslide displacement prediction
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作者 Ziqian Wang Xiangwei Fang +3 位作者 Wengang Zhang Xuanming Ding Luqi Wang Chao Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第7期4211-4226,共16页
Accurate prediction of landslide displacement is crucial for effective early warning of landslide disasters.While most existing prediction methods focus on time-series forecasting for individual monitoring points,ther... Accurate prediction of landslide displacement is crucial for effective early warning of landslide disasters.While most existing prediction methods focus on time-series forecasting for individual monitoring points,there is limited research on the spatiotemporal characteristics of landslide deformation.This paper proposes a novel Multi-Relation Spatiotemporal Graph Residual Network with Multi-Level Feature Attention(MFA-MRSTGRN)that effectively improves the prediction performance of landslide displacement through spatiotemporal fusion.This model integrates internal seepage factors as data feature enhancements with external triggering factors,allowing for accurate capture of the complex spatiotemporal characteristics of landslide displacement and the construction of a multi-source heterogeneous dataset.The MFA-MRSTGRN model incorporates dynamic graph theory and four key modules:multilevel feature attention,temporal-residual decomposition,spatial multi-relational graph convolution,and spatiotemporal fusion prediction.This comprehensive approach enables the efficient analyses of multi-source heterogeneous datasets,facilitating adaptive exploration of the evolving multi-relational,multi-dimensional spatiotemporal complexities in landslides.When applying this model to predict the displacement of the Liangshuijing landslide,we demonstrate that the MFA-MRSTGRN model surpasses traditional models,such as random forest(RF),long short-term memory(LSTM),and spatial temporal graph convolutional networks(ST-GCN)models in terms of various evaluation metrics including mean absolute error(MAE=1.27 mm),root mean square error(RMSE=1.49 mm),mean absolute percentage error(MAPE=0.026),and R-squared(R^(2)=0.88).Furthermore,feature ablation experiments indicate that incorporating internal seepage factors improves the predictive performance of landslide displacement models.This research provides an advanced and reliable method for landslide displacement prediction. 展开更多
关键词 Landslide displacement prediction Spatiotemporal fusion Dynamic graph Data feature enhancement multi-level feature attention
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A robust method for large-scale route optimization on lunar surface utilizing a multi-level map model
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作者 Yutong JIA Shengnan ZHANG +5 位作者 Bin LIU Kaichang DI Bin XIE Jing NAN Chenxu ZHAO Gang WAN 《Chinese Journal of Aeronautics》 2025年第3期134-150,共17页
As we look ahead to future lunar exploration missions, such as crewed lunar exploration and establishing lunar scientific research stations, the lunar rovers will need to cover vast distances. These distances could ra... As we look ahead to future lunar exploration missions, such as crewed lunar exploration and establishing lunar scientific research stations, the lunar rovers will need to cover vast distances. These distances could range from kilometers to tens of kilometers, and even hundreds and thousands of kilometers. Therefore, it is crucial to develop effective long-range path planning for lunar rovers to meet the demands of lunar patrol exploration. This paper presents a hierarchical map model path planning method that utilizes the existing high-resolution images, digital elevation models and mineral abundance maps. The objective is to address the issue of the construction of lunar rover travel costs in the absence of large-scale, high-resolution digital elevation models. This method models the reference and semantic layers using the middle- and low-resolution remote sensing data. The multi-scale obstacles on the lunar surface are extracted by combining the deep learning algorithm on the high-resolution image, and the obstacle avoidance layer is modeled. A two-stage exploratory path planning decision is employed for long-distance driving path planning on a global–local scale. The proposed method analyzes the long-distance accessibility of various areas of scientific significance, such as Rima Bode. A high-precision digital elevation model is created using stereo images to validate the method. Based on the findings, it can be observed that the entire route spans a distance of 930.32 km. The route demonstrates an impressive ability to avoid meter-level impact craters and linear structures while maintaining an average slope of less than 8°. This paper explores scientific research by traversing at least seven basalt units, uncovering the secrets of lunar volcanic activities, and establishing ‘golden spike’ reference points for lunar stratigraphy. The final result of path planning can serve as a valuable reference for the design, mission demonstration, and subsequent project implementation of the new manned lunar rover. 展开更多
关键词 Crewed lunar exploration Long-range path planningi multi-level map Deep learning Volcanic activities
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Multi-level distribution alignment-based domain adaptation for segmentation of 3D neuronal soma images
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作者 Li Ma Xuantai Xu Xiaoquan Yang 《Journal of Innovative Optical Health Sciences》 2025年第6期69-85,共17页
Deep learning networks are increasingly exploited in the field of neuronal soma segmentation.However,annotating dataset is also an expensive and time-consuming task.Unsupervised domain adaptation is an effective metho... Deep learning networks are increasingly exploited in the field of neuronal soma segmentation.However,annotating dataset is also an expensive and time-consuming task.Unsupervised domain adaptation is an effective method to mitigate the problem,which is able to learn an adaptive segmentation model by transferring knowledge from a rich-labeled source domain.In this paper,we propose a multi-level distribution alignment-based unsupervised domain adaptation network(MDA-Net)for segmentation of 3D neuronal soma images.Distribution alignment is performed in both feature space and output space.In the feature space,features from different scales are adaptively fused to enhance the feature extraction capability for small target somata and con-strained to be domain invariant by adversarial adaptation strategy.In the output space,local discrepancy maps that can reveal the spatial structures of somata are constructed on the predicted segmentation results.Then thedistribution alignment is performed on the local discrepancies maps across domains to obtain a superior discrepancy map in the target domain,achieving refined segmentation performance of neuronal somata.Additionally,after a period of distribution align-ment procedure,a portion of target samples with high confident pseudo-labels are selected as training data,which assist in learning a more adaptive segmentation network.We verified the superiority of the proposed algorithm by comparing several domain adaptation networks on two 3D mouse brain neuronal somata datasets and one macaque brain neuronal soma dataset. 展开更多
关键词 Unsupervised domain adaptation multi-level distribution alignment pseudo-labels 3D neuronal soma images
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MLRT-UNet:An Efficient Multi-Level Relation Transformer Based U-Net for Thyroid Nodule Segmentation
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作者 Kaku Haribabu Prasath R Praveen Joe IR 《Computer Modeling in Engineering & Sciences》 2025年第4期413-448,共36页
Thyroid nodules,a common disorder in the endocrine system,require accurate segmentation in ultrasound images for effective diagnosis and treatment.However,achieving precise segmentation remains a challenge due to vari... Thyroid nodules,a common disorder in the endocrine system,require accurate segmentation in ultrasound images for effective diagnosis and treatment.However,achieving precise segmentation remains a challenge due to various factors,including scattering noise,low contrast,and limited resolution in ultrasound images.Although existing segmentation models have made progress,they still suffer from several limitations,such as high error rates,low generalizability,overfitting,limited feature learning capability,etc.To address these challenges,this paper proposes a Multi-level Relation Transformer-based U-Net(MLRT-UNet)to improve thyroid nodule segmentation.The MLRTUNet leverages a novel Relation Transformer,which processes images at multiple scales,overcoming the limitations of traditional encoding methods.This transformer integrates both local and global features effectively through selfattention and cross-attention units,capturing intricate relationships within the data.The approach also introduces a Co-operative Transformer Fusion(CTF)module to combine multi-scale features from different encoding layers,enhancing the model’s ability to capture complex patterns in the data.Furthermore,the Relation Transformer block enhances long-distance dependencies during the decoding process,improving segmentation accuracy.Experimental results showthat the MLRT-UNet achieves high segmentation accuracy,reaching 98.2% on the Digital Database Thyroid Image(DDT)dataset,97.8% on the Thyroid Nodule 3493(TG3K)dataset,and 98.2% on the Thyroid Nodule3K(TN3K)dataset.These findings demonstrate that the proposed method significantly enhances the accuracy of thyroid nodule segmentation,addressing the limitations of existing models. 展开更多
关键词 Thyroid nodules endocrine system multi-level relation transformer U-Net self-attention external attention co-operative transformer fusion thyroid nodules segmentation
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A Novel Reduced Error Pruning Tree Forest with Time-Based Missing Data Imputation(REPTF-TMDI)for Traffic Flow Prediction
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作者 Yunus Dogan Goksu Tuysuzoglu +4 位作者 Elife Ozturk Kiyak Bita Ghasemkhani Kokten Ulas Birant Semih Utku Derya Birant 《Computer Modeling in Engineering & Sciences》 2025年第8期1677-1715,共39页
Accurate traffic flow prediction(TFP)is vital for efficient and sustainable transportation management and the development of intelligent traffic systems.However,missing data in real-world traffic datasets poses a sign... Accurate traffic flow prediction(TFP)is vital for efficient and sustainable transportation management and the development of intelligent traffic systems.However,missing data in real-world traffic datasets poses a significant challenge to maintaining prediction precision.This study introduces REPTF-TMDI,a novel method that combines a Reduced Error Pruning Tree Forest(REPTree Forest)with a newly proposed Time-based Missing Data Imputation(TMDI)approach.The REP Tree Forest,an ensemble learning approach,is tailored for time-related traffic data to enhance predictive accuracy and support the evolution of sustainable urbanmobility solutions.Meanwhile,the TMDI approach exploits temporal patterns to estimate missing values reliably whenever empty fields are encountered.The proposed method was evaluated using hourly traffic flow data from a major U.S.roadway spanning 2012-2018,incorporating temporal features(e.g.,hour,day,month,year,weekday),holiday indicator,and weather conditions(temperature,rain,snow,and cloud coverage).Experimental results demonstrated that the REPTF-TMDI method outperformed conventional imputation techniques across various missing data ratios by achieving an average 11.76%improvement in terms of correlation coefficient(R).Furthermore,REPTree Forest achieved improvements of 68.62%in RMSE and 70.52%in MAE compared to existing state-of-the-art models.These findings highlight the method’s ability to significantly boost traffic flow prediction accuracy,even in the presence of missing data,thereby contributing to the broader objectives of sustainable urban transportation systems. 展开更多
关键词 Machine learning traffic flow prediction missing data imputation reduced error pruning tree(REPTree) sustainable transportation systems traffic management artificial intelligence
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基于IMBS-YOLOv7的轻量化双孢蘑菇品质分级检测方法
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作者 姜凤利 曹丰千 +2 位作者 王迪 李美璇 张芳 《沈阳农业大学学报》 北大核心 2026年第1期100-112,共13页
[目的]为提高双孢蘑菇分级检测精度并便于模型部署到移动端,提出一种基于YOLOv7的轻量化双孢蘑菇分级检测模型。[方法]首先,采用MobileNetV2作为主干网络替换YOLOv7模型的特征提取网络,通过深度可分离卷积有效减少模型参数量并提升推理... [目的]为提高双孢蘑菇分级检测精度并便于模型部署到移动端,提出一种基于YOLOv7的轻量化双孢蘑菇分级检测模型。[方法]首先,采用MobileNetV2作为主干网络替换YOLOv7模型的特征提取网络,通过深度可分离卷积有效减少模型参数量并提升推理速度;其次,引入BiFormer注意力机制,增强模型对双孢蘑菇表面纹理、形态缺陷等细微特征的提取能力;最后,采用SIoU边界框回归损失函数代替CIoU损失函数,显著提升边界框回归精度,增强模型对双孢蘑菇表面轻微缺陷的识别能力。改进后的模型命名为MBS-YOLOv7。[结果]MBS-YOLOv7模型在双孢蘑菇测试集上的平均精度均值(mAP)达到94.1%,相比原始YOLOv7模型提升1.2%,同时模型参数量减少32.8%,实现精度与速度的平衡。在此基础上,为进一步实现模型的轻量化,提出一种融合通道剪枝与知识蒸馏的轻量化模型IMBS-YOLOv7,通过稀疏训练与通道剪枝策略,筛选出最优剪枝率(0.5),并结合知识蒸馏技术,在温度参数T=10时实现软标签信息的最佳传递,有效恢复因剪枝损失的模型精度。最终,IMBS-YOLOv7在保持94.1%mAP的同时,检测速度达121 f·s^(-1),模型体积压缩至12 MB,具备良好的边缘部署能力。[结论]与Faster R-CNN、SSD、YOLOv3、YOLOv5等主流检测算法相比,IMBS-YOLOv7在双孢蘑菇数据集上综合性能最优,满足实时处理要求,为双孢蘑菇在线分级检测提供可靠的技术支持。 展开更多
关键词 双孢蘑菇 品质分级 YOLOv7 注意力机制 知识蒸馏 通道剪枝
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基于YOLOv8的轻量级田间棉花品级检测
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作者 刘杰 黄晓辉 郭敬博 《计算机工程》 北大核心 2026年第1期400-413,共14页
针对复杂田间棉花的多尺度变化导致现存目标检测算法误报率及漏报率较高、现存检测算法计算量较大难以部署到边缘设备中的问题,通过优化特征提取与特征融合,并结合模型剪枝与知识蒸馏技术,提出一种轻量级田间棉花品级检测算法YOLOv8-Cot... 针对复杂田间棉花的多尺度变化导致现存目标检测算法误报率及漏报率较高、现存检测算法计算量较大难以部署到边缘设备中的问题,通过优化特征提取与特征融合,并结合模型剪枝与知识蒸馏技术,提出一种轻量级田间棉花品级检测算法YOLOv8-Cotton。首先,在特征提取网络中设计多尺度卷积(MSConv),其包含不同尺度的卷积核,能够增强网络的特征提取能力;其次,在颈部网络中构建高效的局部特征选择(ELS)机制,在空间维度上捕获水平和垂直方向的特征,抑制不相关区域对预测结果的影响,并利用ELS机制构建新型的分级特征路径融合网络(HL-PAN),利用其上采样特征融合(U-SFF)及下采样特征融合(D-SFF)所产生的互补信息指导特征融合,增强模型对棉花多尺度变化的检测能力;接着,通过分层自适应幅度剪枝(LAMP)模型剪枝算法压缩模型,达到轻量化效果;最后,利用CWD损失函数进行特征蒸馏,以增强轻量化模型的检测性能。实验结果表明,YOLOv8-Cotton在自建数据集上的mAP@0.5、mAP@0.5∶0.95值分别达到75.4%、53.1%,比基线算法分别提高5.1、2.1百分点的同时,模型大小下降4.83 MB,计算量减少5.8×10^(9),并在公开数据集上验证了模型的泛化性。 展开更多
关键词 目标检测 多尺度卷积 特征融合 模型剪枝 知识蒸馏
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基于小胶质细胞介导的突触修剪功能探讨缺血性中风“毒损脑络”理论的病机内涵
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作者 李娜 高永红 +1 位作者 高颖 刘珍洪 《中国中医基础医学杂志》 2026年第2期234-239,共6页
中风病是我国成人致死致残的首位原因,其中缺血性中风占80%以上。中风后常引发不同程度的神经功能缺损,严重影响患者预后。神经可塑性是中风后功能恢复的基础,其中小胶质细胞介导的突触修剪在此过程中起关键调节作用。中风后邪气亢盛,... 中风病是我国成人致死致残的首位原因,其中缺血性中风占80%以上。中风后常引发不同程度的神经功能缺损,严重影响患者预后。神经可塑性是中风后功能恢复的基础,其中小胶质细胞介导的突触修剪在此过程中起关键调节作用。中风后邪气亢盛,败坏形体,转化为毒,损伤脑络,王永炎院士提出中风病“毒损脑络”核心病机假说。脑络又分为脑血络和脑气络。毒蕴日久,过度激活小胶质细胞,一方面放大炎症反应,损伤脑血络导致“络损髓伤”(神经元和突触结构受损);另一方面扰乱突触间信息传递,损伤脑气络导致“络损神消”(神经功能障碍)。因此,小胶质细胞介导的突触修剪异常可能是“毒损脑络”病机演变的微观体现。本文通过系统探讨两者之间的内在关联,赋予“毒损脑络”以新的科学内涵,为中西医结合治疗缺血性中风提供了研究新靶点。 展开更多
关键词 毒损脑络 突触修剪 缺血性中风 小胶质细胞
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