Carotid artery plaques represent a major contributor to the morbidity and mortality associated with cerebrovascular disease,and their clinical significance is largely determined by the risk linked to plaque vulnerabil...Carotid artery plaques represent a major contributor to the morbidity and mortality associated with cerebrovascular disease,and their clinical significance is largely determined by the risk linked to plaque vulnerability.Therefore,classifying plaque risk constitutes one of themost critical tasks in the clinicalmanagement of this condition.While classification models derived from individual medical centers have been extensively investigated,these singlecenter models often fail to generalize well to multi-center data due to variations in ultrasound images caused by differences in physician expertise and equipment.To address this limitation,a Dual-Classifier Label Correction Networkmodel(DCLCN)is proposed for the classification of carotid plaque ultrasound images acrossmultiplemedical centers.TheDCLCNdesigns amulti-center domain adaptationmodule that leverages a dual-classifier strategy to extract knowledge from both source and target centers,thereby reducing feature discrepancies through a domain adaptation layer.Additionally,to mitigate the impact of image noise,a label modeling and correction module is introduced to generate pseudo-labels for the target centers and iteratively refine them using an end-to-end correction mechanism.Experiments on the carotid plaque dataset collected fromthreemedical centers demonstrate that the DCLCN achieves commendable performance and robustness.展开更多
As the integration of medical big data and artificial intelligence advances,the secure sharing of medical data has become a key driving force for advancing disease research and clinical diagnosis.Federated learning,a ...As the integration of medical big data and artificial intelligence advances,the secure sharing of medical data has become a key driving force for advancing disease research and clinical diagnosis.Federated learning,a distributed approach enabling collaborative data processing without sharing raw data,offers promising solutions to challenges in multi-center medical data sharing.This review summarizes the progress of federated learning in multi-center medical data processing,analyzed from four perspectives:system architectures,data distribution strategies,clinical tasks,and algorithmic models.At the same time,this paper explores the challenges in practical applications,such as data heterogeneity,communication overhead,and privacy concerns.It proposes driving future research development by optimizing algorithms,strengthening privacy protection mechanisms,and enhancing computational efficiency.展开更多
BACKGROUND Helicobacter pylori(H.pylori)is a prevalent pathogen associated with various diseases.Cholelithiasis is also a common condition.H.pylori infection has been identified in the biliary system,suggesting its po...BACKGROUND Helicobacter pylori(H.pylori)is a prevalent pathogen associated with various diseases.Cholelithiasis is also a common condition.H.pylori infection has been identified in the biliary system,suggesting its potential involvement in biliary diseases.However,the specific role of H.pylori in the development of cholelithiasis remains inconclusive.AIM To investigate the potential association between H.pylori infection and the development of cholelithiasis.METHODS We performed a retrospective study in more than 70000 subjects in health examination center from 3 institutions in the middle,northern and eastern China,from October 2018 to December 2021,to explore the potential association between H.pylori and cholelithiasis through univariate and multivariate analysis.Meanwhile,the influence of H.pylori on biliary-related parameters was investigated.A comprehensive analysis of previous studies concerned about H.pylori and cholelithiasis was also executed.RESULTS In our multi-center study,H.pylori was positively associated with cholelithiasis[odds ratio(OR)=1.103,95%confidence interval(CI):1.001-1.216,P=0.049].Furthermore,H.pylori patients had less total and direct bilirubin than uninfected patients,while the total cholesterol and low-density lipoprotein cholesterol were more in H.pyloripositive participants(P<0.05).In the published articles,the cohort studies indicated H.pylori was a risk factor of cholelithiasis(hazard ratio=1.3280,95%CI:1.1810-1.4933,P<0.0001).The pooled results of case-control and crosssectional studies showed positive association between H.pylori and cholelithiasis in Asia(OR=1.5993,95%CI:1.0353-2.4706,P=0.034)but not in Europe(OR=1.2770,95%CI:0.8446-1.9308,P=0.246).Besides,H.pylori was related to a higher choledocholithiasis/cholecystolithiasis ratio(OR=3.3215,95%CI:1.1034-9.9986,P=0.033).CONCLUSION H.pylori is positively correlated with cholelithiasis,choledocholithiasis phenotype particularly,especially in Asia,which may be relevant to bilirubin/cholesterol metabolism.Cohort studies confirm an increased risk of cholelithiasis in H.pylori patients.展开更多
Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes...Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.展开更多
Zinc-ion batteries(ZIBs)are inexpensive and safe,but side reactions on the Zn anode and Zn dendrite growth hinder their practical applications.In this study,1,3,5-triformylphloroglycerol(Tp)and various diamine monomer...Zinc-ion batteries(ZIBs)are inexpensive and safe,but side reactions on the Zn anode and Zn dendrite growth hinder their practical applications.In this study,1,3,5-triformylphloroglycerol(Tp)and various diamine monomers(p-phenylenediamine(Pa),benzidine(BD),and 4,4"-diamino-p-terphenyl(DATP))were used to synthesize a series of two-dimensional covalent-organic frameworks(COFs).The resulting COFs were named TpPa,TpBD,and TpDATP,respectively,and they showed uniform zincophilic sites,different pore sizes,and high Young's moduli on the Zn anode.Among them,TpPa and TpBD showed lower surface work functions and higher ion transfer numbers,which were conducive to uniform galvanizing/stripping zinc and inhibited dendrite growth.Theoretical calculations showed that TpPa and TpBD had wider negative potential region and greater adsorption capacity for Zn2+than TpDATP,providing more electron donor sites to coordinate with Zn^(2+).Symmetric cells protected by TpPa and TpBD stably cycled for more than 2300 h,whereas TpDATP@Zn and the bare zinc symmetric cells failed after around 150 and200 h.The full cells containing TpPa and TpBD modification layers also showed excellent cycling capacity at 1 A/g.This study provides comprehensive insights into the construction of highly reversible Zn anodes via COF modification layers for advanced rechargeable ZIBs.展开更多
BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their...BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.展开更多
To obtain the Ti_(p)with different aspect ratios,the Ti_(p)/Mg-5Zn-0.3Ca composite prepared by semi-solid stir casting was subjected to extrusion at 220℃,180℃,and 140℃,respectively.Then,the effect of the Ti_(p)’s ...To obtain the Ti_(p)with different aspect ratios,the Ti_(p)/Mg-5Zn-0.3Ca composite prepared by semi-solid stir casting was subjected to extrusion at 220℃,180℃,and 140℃,respectively.Then,the effect of the Ti_(p)’s aspect ratio on the microstructure,mechanical properties,work hardening and softening behaviors of Ti_(p)/Mg-5Zn-0.3Ca composites was investigated.The results indicated that the Ti_(p)could be elongated obviously after low-temperature extrusion,and the aspect ratio of which would reach to 13.7:1 as the extrusion temperature deceased to 140℃.Then the“Ti/Mg”layer-like structure was formed in the Ti_(p)/Mg-5Zn-0.3Ca composite.Accompanied with the elongation of Ti_(p),the dynamic recrystallized grains and dynamic precipitates were both refined significantly,however,the dynamic recrystallization rate changed a little.The elongated Ti_(p)endowed the Ti_(p)/Mg-5Zn-0.3Ca composites with better matching of strength and toughness without the sacrifice of elongation and bending strain.Both the work hardening rate and softening rate of Ti_(p)/Mg-5Zn-0.3Ca composites increased with the increasing aspect ratio of Ti_(p).The formation of“Ti/Mg”layer-like structure contributed to the redistribution of strain from large aggregations to a network-like distribution,which effectively suppresses the initiation and propagation of micro-cracks,thus enhancing the plasticity of the Ti_(p)/Mg-5Zn-0.3Ca composites.展开更多
Background: First responders (firefighters, paramedics, and police) working in an urban setting can be exposed to a high-stress environment caused by strenuous physical exertion, potentially dangerous work conditions,...Background: First responders (firefighters, paramedics, and police) working in an urban setting can be exposed to a high-stress environment caused by strenuous physical exertion, potentially dangerous work conditions, sleep deprivation due to shift work, poor dietary habits, psychological stress and noise levels that are excessive. This may induce chronic increases in blood pressure. The purpose of this study was to determine the presence of hypertension in people working in occupations generally accepted as high stress in comparison to those working in an environment where less of these obvious high stressors were present. Methods: Resting blood pressure was measured by TrUBP in 1067 on-duty first responders (fire, paramedic, and police), and in participants generally associated with a lower-stress work environment (transit workers, city and bank employees, factory workers and legislature employees). Results: The average age, systolic and diastolic blood pressures were significantly lower in those employees working in a high-stress environment than those in a low-stress job. This difference was observed in both male and female sexes. Conclusions: Our data do not support an association of high resting blood pressure values in those employed in activities typically associated with a high-stress urban working environment.展开更多
Coronavirus is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused by a novel coronavirus belonging to the family Coronaviridae. The disease was first discovered in December 2019 in Wuhan City, Hubei...Coronavirus is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused by a novel coronavirus belonging to the family Coronaviridae. The disease was first discovered in December 2019 in Wuhan City, Hubei Province, China. A few months later, the disease spread all over the world and became an epidemic. The infection for most people is mild to moderate but in Vulnerable groups, if they have the infections, they might experience severe COVID-19. Saudi Arabia initiated its response plan early, and all sectors and agencies worked in an integrated way to combat the disease. It has maintained proper communication during the pandemic and ensured community involvement, epidemiologic surveillance, and activation of rapid response teams. The COVID-19 pandemic significantly affected daily lives. Schools and daycares were closed, education was online, traveling stopped, work was suspended, gathering in social activities and practicing religious rituals, like praying or doing Umrah or Hajj, were banded. Changing lifestyles as a response to COVID-19 impacted whole communities with different categories of children, parents, and families. Women usually take the majority of daily responsibilities. The sudden change in lifestyle during COVID-19 put pressure on mothers, especially those who are working to balance work and family obligations. This study aims to identify the impact of Coronavirus disease 2019 on working mothers in Saudi Arabia. Method: Data of the study was collected through survey posted on social media and analyzed through Excel. It focuses on five aspects: health, lifestyle, social relations, work production and financial status. Our target population was working mothers in Saudi Arabia aged at least 25 years. Results: In this study, all factors affected working mothers categorized under two groups: Social Economic Status and Work suspension. For Social Economic Status factors, we find five factors which are monthly income, main breadwinner, number of children at school age, type of housing, and type of work. Almost all mothers include spiritual activities to their routine to cope with stress during this period. About half of our sample have negative impact on their mental health because they are the main breadwinner, and mothers with a smaller number of children at school age have more challenges to cope up. We found that mothers who own a house or work at governmental sector have better outcome of health. After analyzing data related to Work suspension, we found that mothers who have work support have better management for life circumstances, however their health outcomes were negatively affected. In addition, mothers working at education sector have the highest positive impact among other sectors. Our data shows that working mothers’ abilities to follow up with their children decreased. This study recommends that there is need to invest more in working mothers’ research and supportive programs and ensure collaboration globally to address working mothers’ needs and share experiences.展开更多
This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digiti...This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.展开更多
BACKGROUND Return to work(RTW)and resumption of driving(ROD)are critical factors that influence postoperative quality of life in patients undergoing total hip arthroplasty(THA).However,few studies have focused on the ...BACKGROUND Return to work(RTW)and resumption of driving(ROD)are critical factors that influence postoperative quality of life in patients undergoing total hip arthroplasty(THA).However,few studies have focused on the minimally invasive(MIS)approach and its effect on these outcomes.AIM To investigate RTW and ROD's timelines and influencing factors following anterior MIS-THA.METHODS A retrospective analysis was conducted on 124 patients who underwent anterior MIS-THA.Data on the demographics,occupational physical demands,and RTW/ROD timelines were also collected.Clinical outcomes were measured using standardised scoring systems.Statistical analyses were performed to evaluate the differences between the groups based on employment status and physical workload.RESULTS Among employed patients,the RTW rate was 94.7%,with an average return time of five weeks.The average ROD time was 3.5 weeks across all patients.Despite similar postoperative clinical scores,RTW time was significantly influenced by occupations'physical workload,with heavier physical demands associated with delayed RTW.CONCLUSION Anterior MIS-THA facilitates early RTW and ROD,particularly in occupations with lower physical demands.These findings highlight the importance of considering occupational and physical workload in postoperative care planning to optimize recovery outcomes.展开更多
Dear Editor,I am writing in response to the article“Assessment of nurses’workplace silence behavior motives:A cross-sectional study”by Alhojairi et al.published in the September 2024 issue of the International Jour...Dear Editor,I am writing in response to the article“Assessment of nurses’workplace silence behavior motives:A cross-sectional study”by Alhojairi et al.published in the September 2024 issue of the International Journal of Nursing Sciences[1].This is a letter written by a nurse with 10 years of clinical work experience and a personal interest in team dynamics.I appreciate the authors'recommendations on mitigating workplace silence among nurses to enhance clinical work development,and I believe their proposals could be expanded further.展开更多
With the civilization and modernization of human society,occupational health has emerged as a fundamental goal of social justice,as highlighted in the United Nations'Sustainable Development Goals(SDGs)since 2016.S...With the civilization and modernization of human society,occupational health has emerged as a fundamental goal of social justice,as highlighted in the United Nations'Sustainable Development Goals(SDGs)since 2016.Specifically,"SDG Goal 1:No Poverty","SDG 3:Good Health and Well-being",and"SDG 8:Decent Work and Economic Growth",are interconnected with other SDGs to support the pursuit of occupational health.展开更多
This paper explored how the work hardening process enhances the yield strength(YS)of magnesium alloy and established a novel quantitative relationship between microstructure and YS.The YS of an extruded Mg–Nd–Zn–Zr...This paper explored how the work hardening process enhances the yield strength(YS)of magnesium alloy and established a novel quantitative relationship between microstructure and YS.The YS of an extruded Mg–Nd–Zn–Zr alloy was nearly tripled by rotary swaging at 200℃,attributing to dislocation accumulation,grain fragmentation,and basal texture formation.A modified Hall–Petch relationship(GM–HP)was established by introducing the equivalent orientation factor and dislocation density to accurately quantify the YS and the contribution of each strengthening mechanism.The contributions of dislocation hardening and grain boundary strengthening were multiplied by the strong basal texture.This paper offered valuable insights and guidance for designing and optimizing high-strength wrought magnesium alloys and their plastic processing methods.展开更多
This paper defines and explores the concept of social reproduction work,highlighting its significance and the fact that women are its primary contributors.It identifies key social issues faced by social reproduction w...This paper defines and explores the concept of social reproduction work,highlighting its significance and the fact that women are its primary contributors.It identifies key social issues faced by social reproduction workers,including marginalization,neglect,and unequal access to resources.Additionally,the study examines the primary challenges encountered by these workers:the lack of direct economic benefits,difficulty in balancing work and family responsibilities,and the significant physical and mental strain associated with unpaid labor.Using the theoretical framework of the capitalist economic system,the paper delves into the root causes of the caregiving crisis.Furthermore,it critiques the applicability of reproduction work theories in explaining unpaid care work in the Global South.Three key limitations are outlined:the neglect of informal economic systems in the Global South,persistent gender inequality,and the dynamic nature of global economic migration.展开更多
Find It Why was the third pig the smartest?nee upon a time,three little pigs lived with their mother.One day,she told them,"You are big now.Go build homes and take care of yourselves."So,the three pigs left ...Find It Why was the third pig the smartest?nee upon a time,three little pigs lived with their mother.One day,she told them,"You are big now.Go build homes and take care of yourselves."So,the three pigs left and went to find places to live.The first little pig didn't like to work hard.He found some straw.展开更多
Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a usefu...Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a useful and valid tool for spatial working memory and attention studies in the fields of cognitive psychology,education,and psychiatry.The repeated administration of working memory capacity tests is common in clinical and research settings.Studies suggest that repeated cognitive tests may improve the performance scores also known as retest effects.The systematic investigation of retest effects in SWAPS is critical for interpreting scientific results,but it is still not fully developed.To address this,we recruited 77 college students aged 18–21 years and used SWAPS comprising 72 trials with different memory loads,learning time,and delay span.We repeated the test once a week for five weeks to investigate the retest effects of SWAPS.There were significant retest effects in the first two tests:the accuracy of the SWAPS tests significantly increased,and then stabilized.These findings provide useful information for researchers to appropriately use or interpret the repeated working memory tests.Further experiments are still needed to clarify the factors that mediate the retest effects,and find out the cognitive mechanism that influences the retest effects.展开更多
基金supported by Shanghai Technical Service Computing Center of Science and Engineering,Shanghai University.
文摘Carotid artery plaques represent a major contributor to the morbidity and mortality associated with cerebrovascular disease,and their clinical significance is largely determined by the risk linked to plaque vulnerability.Therefore,classifying plaque risk constitutes one of themost critical tasks in the clinicalmanagement of this condition.While classification models derived from individual medical centers have been extensively investigated,these singlecenter models often fail to generalize well to multi-center data due to variations in ultrasound images caused by differences in physician expertise and equipment.To address this limitation,a Dual-Classifier Label Correction Networkmodel(DCLCN)is proposed for the classification of carotid plaque ultrasound images acrossmultiplemedical centers.TheDCLCNdesigns amulti-center domain adaptationmodule that leverages a dual-classifier strategy to extract knowledge from both source and target centers,thereby reducing feature discrepancies through a domain adaptation layer.Additionally,to mitigate the impact of image noise,a label modeling and correction module is introduced to generate pseudo-labels for the target centers and iteratively refine them using an end-to-end correction mechanism.Experiments on the carotid plaque dataset collected fromthreemedical centers demonstrate that the DCLCN achieves commendable performance and robustness.
基金supported and funded by the National Natural Science Foundation of China(82101079)the Key R&D Program of Jiangsu Province(BE2023836)the National Key Research and Development Program of China(SQ2023YFC2400025).
文摘As the integration of medical big data and artificial intelligence advances,the secure sharing of medical data has become a key driving force for advancing disease research and clinical diagnosis.Federated learning,a distributed approach enabling collaborative data processing without sharing raw data,offers promising solutions to challenges in multi-center medical data sharing.This review summarizes the progress of federated learning in multi-center medical data processing,analyzed from four perspectives:system architectures,data distribution strategies,clinical tasks,and algorithmic models.At the same time,this paper explores the challenges in practical applications,such as data heterogeneity,communication overhead,and privacy concerns.It proposes driving future research development by optimizing algorithms,strengthening privacy protection mechanisms,and enhancing computational efficiency.
基金Supported by the National Natural Science Foundation of China,No.82270594the National Natural Science Foundation for Youths of China,No.82103151+1 种基金the Outstanding Youth Foundation of Hunan Province,No.2022JJ20092the Wisdom Accumulation and Talent Cultivation Project of Third Xiangya Hospital of Central South University,No.YX202103.
文摘BACKGROUND Helicobacter pylori(H.pylori)is a prevalent pathogen associated with various diseases.Cholelithiasis is also a common condition.H.pylori infection has been identified in the biliary system,suggesting its potential involvement in biliary diseases.However,the specific role of H.pylori in the development of cholelithiasis remains inconclusive.AIM To investigate the potential association between H.pylori infection and the development of cholelithiasis.METHODS We performed a retrospective study in more than 70000 subjects in health examination center from 3 institutions in the middle,northern and eastern China,from October 2018 to December 2021,to explore the potential association between H.pylori and cholelithiasis through univariate and multivariate analysis.Meanwhile,the influence of H.pylori on biliary-related parameters was investigated.A comprehensive analysis of previous studies concerned about H.pylori and cholelithiasis was also executed.RESULTS In our multi-center study,H.pylori was positively associated with cholelithiasis[odds ratio(OR)=1.103,95%confidence interval(CI):1.001-1.216,P=0.049].Furthermore,H.pylori patients had less total and direct bilirubin than uninfected patients,while the total cholesterol and low-density lipoprotein cholesterol were more in H.pyloripositive participants(P<0.05).In the published articles,the cohort studies indicated H.pylori was a risk factor of cholelithiasis(hazard ratio=1.3280,95%CI:1.1810-1.4933,P<0.0001).The pooled results of case-control and crosssectional studies showed positive association between H.pylori and cholelithiasis in Asia(OR=1.5993,95%CI:1.0353-2.4706,P=0.034)but not in Europe(OR=1.2770,95%CI:0.8446-1.9308,P=0.246).Besides,H.pylori was related to a higher choledocholithiasis/cholecystolithiasis ratio(OR=3.3215,95%CI:1.1034-9.9986,P=0.033).CONCLUSION H.pylori is positively correlated with cholelithiasis,choledocholithiasis phenotype particularly,especially in Asia,which may be relevant to bilirubin/cholesterol metabolism.Cohort studies confirm an increased risk of cholelithiasis in H.pylori patients.
基金funded by Humanities and Social Sciences Foundation and Natural Science Foundation of Nanjing University of Posts and Telecommunications(NYY222055,NY224176)General Subject of Educational Science Planning in Jiangsu Province(C/2024/01/76)National Natural Science Foundation of China(62307025).
文摘Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.
基金financially supported by the National Natural Science Foundation of China(62464010)Spring City Plan-Special Program for Young Talents(K202005007)+3 种基金Yunnan Talents Support Plan for Yong Talents(XDYC-QNRC-2022-0482)Yunnan Local Colleges Applied Basic Research Projects(202101BA070001-138)Key Laboratory of Artificial Microstructures in Yunnan Higher EducationFrontier Research Team of Kunming University 2023。
文摘Zinc-ion batteries(ZIBs)are inexpensive and safe,but side reactions on the Zn anode and Zn dendrite growth hinder their practical applications.In this study,1,3,5-triformylphloroglycerol(Tp)and various diamine monomers(p-phenylenediamine(Pa),benzidine(BD),and 4,4"-diamino-p-terphenyl(DATP))were used to synthesize a series of two-dimensional covalent-organic frameworks(COFs).The resulting COFs were named TpPa,TpBD,and TpDATP,respectively,and they showed uniform zincophilic sites,different pore sizes,and high Young's moduli on the Zn anode.Among them,TpPa and TpBD showed lower surface work functions and higher ion transfer numbers,which were conducive to uniform galvanizing/stripping zinc and inhibited dendrite growth.Theoretical calculations showed that TpPa and TpBD had wider negative potential region and greater adsorption capacity for Zn2+than TpDATP,providing more electron donor sites to coordinate with Zn^(2+).Symmetric cells protected by TpPa and TpBD stably cycled for more than 2300 h,whereas TpDATP@Zn and the bare zinc symmetric cells failed after around 150 and200 h.The full cells containing TpPa and TpBD modification layers also showed excellent cycling capacity at 1 A/g.This study provides comprehensive insights into the construction of highly reversible Zn anodes via COF modification layers for advanced rechargeable ZIBs.
基金Supported by the Chongqing Medical University Program for Youth Innovation in Future Medicine,No.W0019Chongqing Municipal Education Commission’s 14th Five-Year Key Discipline Support Project,No.20240101 and No.20240102。
文摘BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their RTW process.Hence,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC survivors.AIM To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW outcomes.METHODS A cross-sectional investigation was adopted in this study.From September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in Chongqing.The investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and FT.To analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were used.RESULTS A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 days.Cox regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further improvement.Elevated levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC survivors.Health professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.
基金supported by the“National Natural Science Foundation of China”(Grants.52271109 and 52001223)Support from the“National Key Research and Development Program for Young Scientists”(Grant.2021YFB3703300)+1 种基金the Major Special Plan for Science and Technology in Shanxi Province(202201050201012)the Special Fund Project for Guiding Local Science and Technology Development by the Central Government(Grant.YDZJSX2021B019)。
文摘To obtain the Ti_(p)with different aspect ratios,the Ti_(p)/Mg-5Zn-0.3Ca composite prepared by semi-solid stir casting was subjected to extrusion at 220℃,180℃,and 140℃,respectively.Then,the effect of the Ti_(p)’s aspect ratio on the microstructure,mechanical properties,work hardening and softening behaviors of Ti_(p)/Mg-5Zn-0.3Ca composites was investigated.The results indicated that the Ti_(p)could be elongated obviously after low-temperature extrusion,and the aspect ratio of which would reach to 13.7:1 as the extrusion temperature deceased to 140℃.Then the“Ti/Mg”layer-like structure was formed in the Ti_(p)/Mg-5Zn-0.3Ca composite.Accompanied with the elongation of Ti_(p),the dynamic recrystallized grains and dynamic precipitates were both refined significantly,however,the dynamic recrystallization rate changed a little.The elongated Ti_(p)endowed the Ti_(p)/Mg-5Zn-0.3Ca composites with better matching of strength and toughness without the sacrifice of elongation and bending strain.Both the work hardening rate and softening rate of Ti_(p)/Mg-5Zn-0.3Ca composites increased with the increasing aspect ratio of Ti_(p).The formation of“Ti/Mg”layer-like structure contributed to the redistribution of strain from large aggregations to a network-like distribution,which effectively suppresses the initiation and propagation of micro-cracks,thus enhancing the plasticity of the Ti_(p)/Mg-5Zn-0.3Ca composites.
文摘Background: First responders (firefighters, paramedics, and police) working in an urban setting can be exposed to a high-stress environment caused by strenuous physical exertion, potentially dangerous work conditions, sleep deprivation due to shift work, poor dietary habits, psychological stress and noise levels that are excessive. This may induce chronic increases in blood pressure. The purpose of this study was to determine the presence of hypertension in people working in occupations generally accepted as high stress in comparison to those working in an environment where less of these obvious high stressors were present. Methods: Resting blood pressure was measured by TrUBP in 1067 on-duty first responders (fire, paramedic, and police), and in participants generally associated with a lower-stress work environment (transit workers, city and bank employees, factory workers and legislature employees). Results: The average age, systolic and diastolic blood pressures were significantly lower in those employees working in a high-stress environment than those in a low-stress job. This difference was observed in both male and female sexes. Conclusions: Our data do not support an association of high resting blood pressure values in those employed in activities typically associated with a high-stress urban working environment.
文摘Coronavirus is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused by a novel coronavirus belonging to the family Coronaviridae. The disease was first discovered in December 2019 in Wuhan City, Hubei Province, China. A few months later, the disease spread all over the world and became an epidemic. The infection for most people is mild to moderate but in Vulnerable groups, if they have the infections, they might experience severe COVID-19. Saudi Arabia initiated its response plan early, and all sectors and agencies worked in an integrated way to combat the disease. It has maintained proper communication during the pandemic and ensured community involvement, epidemiologic surveillance, and activation of rapid response teams. The COVID-19 pandemic significantly affected daily lives. Schools and daycares were closed, education was online, traveling stopped, work was suspended, gathering in social activities and practicing religious rituals, like praying or doing Umrah or Hajj, were banded. Changing lifestyles as a response to COVID-19 impacted whole communities with different categories of children, parents, and families. Women usually take the majority of daily responsibilities. The sudden change in lifestyle during COVID-19 put pressure on mothers, especially those who are working to balance work and family obligations. This study aims to identify the impact of Coronavirus disease 2019 on working mothers in Saudi Arabia. Method: Data of the study was collected through survey posted on social media and analyzed through Excel. It focuses on five aspects: health, lifestyle, social relations, work production and financial status. Our target population was working mothers in Saudi Arabia aged at least 25 years. Results: In this study, all factors affected working mothers categorized under two groups: Social Economic Status and Work suspension. For Social Economic Status factors, we find five factors which are monthly income, main breadwinner, number of children at school age, type of housing, and type of work. Almost all mothers include spiritual activities to their routine to cope with stress during this period. About half of our sample have negative impact on their mental health because they are the main breadwinner, and mothers with a smaller number of children at school age have more challenges to cope up. We found that mothers who own a house or work at governmental sector have better outcome of health. After analyzing data related to Work suspension, we found that mothers who have work support have better management for life circumstances, however their health outcomes were negatively affected. In addition, mothers working at education sector have the highest positive impact among other sectors. Our data shows that working mothers’ abilities to follow up with their children decreased. This study recommends that there is need to invest more in working mothers’ research and supportive programs and ensure collaboration globally to address working mothers’ needs and share experiences.
文摘This study proposes a novel approach to optimizing individual work schedules for book digitization using mixed-integer programming (MIP). By leveraging the power of MIP solvers, we aimed to minimize the overall digitization time while considering various constraints and process dependencies. The book digitization process involves three key steps: cutting, scanning, and binding. Each step has specific requirements and limitations such as the number of pages that can be processed simultaneously and potential bottlenecks. To address these complexities, we formulate the problem as a one-machine job shop scheduling problem with additional constraints to capture the unique characteristics of book digitization. We conducted a series of experiments to evaluate the performance of our proposed approach. By comparing the optimized schedules with the baseline approach, we demonstrated significant reductions in the overall processing time. In addition, we analyzed the impact of different weighting schemes on the optimization results, highlighting the importance of identifying and prioritizing critical processes. Our findings suggest that MIP-based optimization can be a valuable tool for improving the efficiency of individual work schedules, even in seemingly simple tasks, such as book digitization. By carefully considering specific constraints and objectives, we can save time and leverage resources by carefully considering specific constraints and objectives.
基金approved by the Institutional Ethics Committee of Shizuoka Red Cross Hospital(No.2023-36,approval date:January 12,2024).
文摘BACKGROUND Return to work(RTW)and resumption of driving(ROD)are critical factors that influence postoperative quality of life in patients undergoing total hip arthroplasty(THA).However,few studies have focused on the minimally invasive(MIS)approach and its effect on these outcomes.AIM To investigate RTW and ROD's timelines and influencing factors following anterior MIS-THA.METHODS A retrospective analysis was conducted on 124 patients who underwent anterior MIS-THA.Data on the demographics,occupational physical demands,and RTW/ROD timelines were also collected.Clinical outcomes were measured using standardised scoring systems.Statistical analyses were performed to evaluate the differences between the groups based on employment status and physical workload.RESULTS Among employed patients,the RTW rate was 94.7%,with an average return time of five weeks.The average ROD time was 3.5 weeks across all patients.Despite similar postoperative clinical scores,RTW time was significantly influenced by occupations'physical workload,with heavier physical demands associated with delayed RTW.CONCLUSION Anterior MIS-THA facilitates early RTW and ROD,particularly in occupations with lower physical demands.These findings highlight the importance of considering occupational and physical workload in postoperative care planning to optimize recovery outcomes.
文摘Dear Editor,I am writing in response to the article“Assessment of nurses’workplace silence behavior motives:A cross-sectional study”by Alhojairi et al.published in the September 2024 issue of the International Journal of Nursing Sciences[1].This is a letter written by a nurse with 10 years of clinical work experience and a personal interest in team dynamics.I appreciate the authors'recommendations on mitigating workplace silence among nurses to enhance clinical work development,and I believe their proposals could be expanded further.
文摘With the civilization and modernization of human society,occupational health has emerged as a fundamental goal of social justice,as highlighted in the United Nations'Sustainable Development Goals(SDGs)since 2016.Specifically,"SDG Goal 1:No Poverty","SDG 3:Good Health and Well-being",and"SDG 8:Decent Work and Economic Growth",are interconnected with other SDGs to support the pursuit of occupational health.
基金supported by National Natural Science Foundation of China(Grant No.51975146)Natural Science Foundation of Shandong Province(Grant No.ZR2020QE171)。
文摘This paper explored how the work hardening process enhances the yield strength(YS)of magnesium alloy and established a novel quantitative relationship between microstructure and YS.The YS of an extruded Mg–Nd–Zn–Zr alloy was nearly tripled by rotary swaging at 200℃,attributing to dislocation accumulation,grain fragmentation,and basal texture formation.A modified Hall–Petch relationship(GM–HP)was established by introducing the equivalent orientation factor and dislocation density to accurately quantify the YS and the contribution of each strengthening mechanism.The contributions of dislocation hardening and grain boundary strengthening were multiplied by the strong basal texture.This paper offered valuable insights and guidance for designing and optimizing high-strength wrought magnesium alloys and their plastic processing methods.
文摘This paper defines and explores the concept of social reproduction work,highlighting its significance and the fact that women are its primary contributors.It identifies key social issues faced by social reproduction workers,including marginalization,neglect,and unequal access to resources.Additionally,the study examines the primary challenges encountered by these workers:the lack of direct economic benefits,difficulty in balancing work and family responsibilities,and the significant physical and mental strain associated with unpaid labor.Using the theoretical framework of the capitalist economic system,the paper delves into the root causes of the caregiving crisis.Furthermore,it critiques the applicability of reproduction work theories in explaining unpaid care work in the Global South.Three key limitations are outlined:the neglect of informal economic systems in the Global South,persistent gender inequality,and the dynamic nature of global economic migration.
文摘Find It Why was the third pig the smartest?nee upon a time,three little pigs lived with their mother.One day,she told them,"You are big now.Go build homes and take care of yourselves."So,the three pigs left and went to find places to live.The first little pig didn't like to work hard.He found some straw.
基金the National Natural Science Foundation of China(No.91632103)the Shanghai Education Commission Research and Innovation Program(No.2019-01-07-00-02-E00037)+2 种基金the Program of Shanghai Subject Chief Scientist(No.17XD1401700)the Higher Education Disciplinary Innovation Programthe“Eastern Scholar”Project。
文摘Working memory is a core cognitive function that supports goal-directed behavior and complex thought.We developed a spatial working memory and attention test on paired symbols(SWAPS)which has been proved to be a useful and valid tool for spatial working memory and attention studies in the fields of cognitive psychology,education,and psychiatry.The repeated administration of working memory capacity tests is common in clinical and research settings.Studies suggest that repeated cognitive tests may improve the performance scores also known as retest effects.The systematic investigation of retest effects in SWAPS is critical for interpreting scientific results,but it is still not fully developed.To address this,we recruited 77 college students aged 18–21 years and used SWAPS comprising 72 trials with different memory loads,learning time,and delay span.We repeated the test once a week for five weeks to investigate the retest effects of SWAPS.There were significant retest effects in the first two tests:the accuracy of the SWAPS tests significantly increased,and then stabilized.These findings provide useful information for researchers to appropriately use or interpret the repeated working memory tests.Further experiments are still needed to clarify the factors that mediate the retest effects,and find out the cognitive mechanism that influences the retest effects.
