Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with ca...Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.展开更多
OBJECTIVE:To investigate antihypertensive effect in rats in order to confirm that twirling reinforcing-reducing manipulation(TRRM)might be the central mechanism underlying the action.METHODS:In the study,^(18)F-2-fluo...OBJECTIVE:To investigate antihypertensive effect in rats in order to confirm that twirling reinforcing-reducing manipulation(TRRM)might be the central mechanism underlying the action.METHODS:In the study,^(18)F-2-fluoro-deoxy-D-glucose positron emission tomography(18 F-FDG-PET)was employed.Fifity-six spontaneous hypertensive rats(SHRs)were randomly divided into a model group,a single-needle acupuncture(SNA)group,a twirling reinforcing group(SNA+TRF)and a twirling reducing(SNA+TRD)group.Fourteen Wistar rats were assigned to the control group.The acupuncture intervention at Taichong(LR 3)acupoint was administered once daily in the SNA,SNA+TRF and SNA+TRD groups for 14 days,with 1 d interval between the two weeks.The blood pressure(BP)of all rats was measured repeatedly and18 F-FDG-PET scans were conducted on the 14 th day.PET images were processed with Statistical Parametric Mapping 8.0.RESULTS:After the intervention,systolic BP showed a significant decrease in the SNA,SNA+TRF and SNA+TRD versus the model groups(all P<0.01)and in the SNA+TRF and SNA+TRD versus the SNA groups(both P<0.01),with the SNA+TRD group exhibited the best antihypertensive effect(P<0.01).The key brain regions activated by TRRM were mainly concentrated in the cerebellum,hippocampus,hypothalamus,medulla oblongata,insular cortex,midbrain,thalamus and visual cortex.CONCLUTION:TRRM could significantly lower the BP of SHRs by improving the cerebral glucose metabolism of the activated key brain regions and the underlying central mechanism may be related to the central rennin-angiotensin system and neurotransmission.展开更多
Objective： To observe the clinical effect of lower-reinforcing and upper-reducing acupuncture method for hyperplasia of mammary gland （HMG） and its influence on estradiol （E2） and progesterone （P）. Methods： A ...Objective： To observe the clinical effect of lower-reinforcing and upper-reducing acupuncture method for hyperplasia of mammary gland （HMG） and its influence on estradiol （E2） and progesterone （P）. Methods： A randomized, single-blinded and controlled trial was conducted. A total of 124 cases conforming to the inclusion criteria were randomized by random number table into a treatment group and a control group, with 62 cases in each group. Patients in both groups received acupuncture therapy at the same acupoints, while patients in the treatment group received lower-reinforcing and upper-reducing method, and patients in the control group received even reinforcing-reducing manipulation. The treatment started around 10 d before menstruation and was conducted every other day. Patients received 5 treatments in each menstruation cycle for consecutive 3 cycles. The levels of E2, P and E2/P and clinical efficacy were measured before and after treatment. Results： After treatment, the breast lump size, pain intensity and concomitant symptoms score in both groups were substantially lower than those before treatment, showing statistical significances （all P〈0.01）, and the improvement in the treatment group was higher than that in the control group, and the between-group comparisons showed statistical significances （all P〈0.01）. After treatment, the overall effective rate was 91.9% in the treatment group, higher than 72.6% in the control group, and the between-group comparison showed a statistical significance （P〈0.01）. After treatment, levels of E2, P and E2/P value showed no statistical significance when compared with those before treatment in the two groups （all P〉0.05）. Conclusion： Lower-reinforcing and upper-reducing acupuncture method can effectively alleviate clinical symptoms and signs in HMG patients, and produce a better effect than even reinforcing-reducing manipulation. The majority of HMG patients＇ E2, P level and E2/P value were not beyond the normal ranges; therefore, acupuncture showed no substantial influence on E2 and P levels and E2/P value.展开更多
文摘Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.
基金Supported by the National Natural Science Foundation of China(Use PET Brain Imaging Technology to Study the Acupuncture Manipulation of Twirling Reinforcing-Reducing Regulation in Spontaneously Hypertensive Rats by Central Integration Signaling Network Construction,No.8157150840)
文摘OBJECTIVE:To investigate antihypertensive effect in rats in order to confirm that twirling reinforcing-reducing manipulation(TRRM)might be the central mechanism underlying the action.METHODS:In the study,^(18)F-2-fluoro-deoxy-D-glucose positron emission tomography(18 F-FDG-PET)was employed.Fifity-six spontaneous hypertensive rats(SHRs)were randomly divided into a model group,a single-needle acupuncture(SNA)group,a twirling reinforcing group(SNA+TRF)and a twirling reducing(SNA+TRD)group.Fourteen Wistar rats were assigned to the control group.The acupuncture intervention at Taichong(LR 3)acupoint was administered once daily in the SNA,SNA+TRF and SNA+TRD groups for 14 days,with 1 d interval between the two weeks.The blood pressure(BP)of all rats was measured repeatedly and18 F-FDG-PET scans were conducted on the 14 th day.PET images were processed with Statistical Parametric Mapping 8.0.RESULTS:After the intervention,systolic BP showed a significant decrease in the SNA,SNA+TRF and SNA+TRD versus the model groups(all P<0.01)and in the SNA+TRF and SNA+TRD versus the SNA groups(both P<0.01),with the SNA+TRD group exhibited the best antihypertensive effect(P<0.01).The key brain regions activated by TRRM were mainly concentrated in the cerebellum,hippocampus,hypothalamus,medulla oblongata,insular cortex,midbrain,thalamus and visual cortex.CONCLUTION:TRRM could significantly lower the BP of SHRs by improving the cerebral glucose metabolism of the activated key brain regions and the underlying central mechanism may be related to the central rennin-angiotensin system and neurotransmission.
文摘Objective： To observe the clinical effect of lower-reinforcing and upper-reducing acupuncture method for hyperplasia of mammary gland （HMG） and its influence on estradiol （E2） and progesterone （P）. Methods： A randomized, single-blinded and controlled trial was conducted. A total of 124 cases conforming to the inclusion criteria were randomized by random number table into a treatment group and a control group, with 62 cases in each group. Patients in both groups received acupuncture therapy at the same acupoints, while patients in the treatment group received lower-reinforcing and upper-reducing method, and patients in the control group received even reinforcing-reducing manipulation. The treatment started around 10 d before menstruation and was conducted every other day. Patients received 5 treatments in each menstruation cycle for consecutive 3 cycles. The levels of E2, P and E2/P and clinical efficacy were measured before and after treatment. Results： After treatment, the breast lump size, pain intensity and concomitant symptoms score in both groups were substantially lower than those before treatment, showing statistical significances （all P〈0.01）, and the improvement in the treatment group was higher than that in the control group, and the between-group comparisons showed statistical significances （all P〈0.01）. After treatment, the overall effective rate was 91.9% in the treatment group, higher than 72.6% in the control group, and the between-group comparison showed a statistical significance （P〈0.01）. After treatment, levels of E2, P and E2/P value showed no statistical significance when compared with those before treatment in the two groups （all P〉0.05）. Conclusion： Lower-reinforcing and upper-reducing acupuncture method can effectively alleviate clinical symptoms and signs in HMG patients, and produce a better effect than even reinforcing-reducing manipulation. The majority of HMG patients＇ E2, P level and E2/P value were not beyond the normal ranges; therefore, acupuncture showed no substantial influence on E2 and P levels and E2/P value.
