Objective:To analyze the impact of maternal-infant separation on the physical and mental state of high-risk pregnancy patients and explore the clinical efficacy of targeted nursing interventions.Methods:A total of 80 ...Objective:To analyze the impact of maternal-infant separation on the physical and mental state of high-risk pregnancy patients and explore the clinical efficacy of targeted nursing interventions.Methods:A total of 80 high-risk pregnancy patients treated in our hospital from January 2023 to January 2024 were selected as the study subjects.These patients were randomly divided into an observation group and a control group(40 cases each)using a random number table.The control group received routine high-risk pregnancy nursing care,while the observation group received specialized maternal-infant separation nursing interventions in addition to routine care.The psychological and physiological states and nursing satisfaction of the two groups were compared before and after the intervention.Results:The SAS scores,SDS scores,and sleep quality scores of the observation group were significantly lower than those of the control group,with statistically significant differences(p<0.05).The incidence of postpartum hemorrhage in the observation group was significantly lower than that in the control group,and the initiation time of lactation was significantly earlier than that in the control group,with both differences being statistically significant(p<0.05).The nursing satisfaction of the observation group was significantly higher than that of the control group(80%vs.32/40),with a statistically significant difference(p<0.05).Conclusion:Maternal-infant separation exacerbates anxiety and depression in high-risk pregnancy patients,reduces sleep quality,increases the risk of postpartum hemorrhage,and delays the initiation of lactation.Specialized nursing interventions for maternal-infant separation can improve the physical and mental state of high-risk pregnancy patients,reduce the incidence of postpartum complications,and enhance nursing satisfaction,making them worthy of clinical application and promotion.展开更多
Objectives: Since it has been suggested that moderate alcohol drinking would increase insulin sensitivity, which could benefit Gestational Diabetes Mellitus (GDM), the study aimed at evaluating alcohol consumption dur...Objectives: Since it has been suggested that moderate alcohol drinking would increase insulin sensitivity, which could benefit Gestational Diabetes Mellitus (GDM), the study aimed at evaluating alcohol consumption during pregnancy, and seeing whether this consumption influences GDM detection and maternal/perinatal outcomes. Study design: Women with already known diabetes and those with multiple pregnancy were excluded. All other pregnant women attending antenatal care unit of the university clinics, Kinshasa, DR Congo during the period from 1 March throughout 31 October 2010, were invited at 24-week gestation to enroll in O’Sullivan blood glucose testing and if eligible in 100-gram oral glucose tolerance test. Alcohol consumption, risk factors for GDM, and general characteristics such as age, parity, gestity, BMI, fat mass were registered. Diagnosed GDM was first treated with diet and exercise, thereafter with Metformin, and if necessary with insulin. For other (normal) women data remained blinded until confinement. Maternal and infant’s adverse outcomes such as maternal urinary infection, preeclampsia, cesarean section, intrauterine growth retardation, birth weight percentile 90 in our milieu), Apgar score at the first minute < 7, shoulder dystocia or other birth injury, neonatal hypoglycemia and fetal alcohol syndrome (FAS) were compared and analyzed according to GDM diagnosis as well to alcohol status. Results: Up to 240 pregnant women accepted to enroll into the study. Alcohol consumption concerned 78 (32.5%) of the women, most of them (61 = 25.42%) being heavy consumers. Risk factors for GDM and Physical and blood glucose characteristics were alike (p not significant) in both consumers and non consumers, except for history of HTA in the family that was significantly more frequent (p = 0.02) among drinkers. GDM’s prevalence was 9%. No adverse outcome was more prominent in any subgroup, except Apgar score < 7 at the first minute that was more frequent (p = 0.038) among neonates of GDM mothers. No FAS, neither shoulder dystocia nor neonatal hypoglycemia were diagnosed. When alcohol status was considered, Birthweight ≥ 3800 g was found more frequent (p = 0.0284) in alcohol consumers than in abstainers. Risk of this outcome was three times higher when history of family hypertension was present (odds ratio 2.694;CI: 0.536 - 13.544). Conclusions: The prevalence of alcohol consumption by pregnant women of our series (32.5%) seems not to impact the detection of GDM (9%). FAS was not diagnosed. Lack of significant differences in adverse outcomes between GDM and non GDM could be attributed to huge follow-up of GDM women. Influence of alcohol consumption on birth weight mostly in setting of familial history of hypertension remains to be addressed.展开更多
Nutrients in human milk,including minerals,relate growth and development of breast-fed infants.Tibetan mother-infant dyads possess unique characteristics on early nutrition due to their featured long-lasting lifestyle...Nutrients in human milk,including minerals,relate growth and development of breast-fed infants.Tibetan mother-infant dyads possess unique characteristics on early nutrition due to their featured long-lasting lifestyle.This study longitudinally investigated the relationship between the mineral composition in human milk and the Z-scores of infants among Tibetan mother-infant dyads during their first 6 months postpartum through a prospective cohort study.The results show that the minerals of Na,Mg,K,Ca,Cu,Zn,and Se were of higher levels in colostrum than other lactation stages.Several minerals were below the recommended values for infants according to Chinese dietary guidelines.Besides,a large proportion of infant Z-scores were below-2 as lactation period continued.Multivariate statistical analysis revealed that classifications and correlations in varying degrees were observed between minerals in human milk and infant Z-scores.These findings will be advantageous for research upon Chinese early nutrition and progress of tailor-made infant formula.展开更多
Aim: To investigate the impact of postnatal depressive symptoms and infant sex on perceived and observed mother-infant interaction among rural Bangladeshi women. Methods: Fifty women with depressive symptoms and their...Aim: To investigate the impact of postnatal depressive symptoms and infant sex on perceived and observed mother-infant interaction among rural Bangladeshi women. Methods: Fifty women with depressive symptoms and their infants at 2 - 3 months were compared with 50 women without depressed symptoms and their infants, matched on geographic areas, parity and infant sex. The Edinburgh Postnatal Depression Scale assessed depressive symptoms, the Postpartum Bonding Questionnaire assessed the mother’s perception of bonding with the infant and mother-infant interactions were videotaped and analyzed with the Global Rating Scale. Results: Mothers with depressive symptoms were poorer, were less educated and rated lower infant bonding than mothers without depressive symptoms (p = 0.03), yet objective observation revealed no difference between the two groups regarding maternal interactive behavior (p = 0.57). However, infants, particularly boys (p = 0.002), of mothers with depressive symptoms fretted more in mother-infant interaction than infants of mothers without depressive symptoms (p = 0.009). Conclusion: Although mothers with depressive symptoms did not show less sensitivity in interactive behavior at 2 - 3 months than those without depressive symptoms, our results indicate that infants, particularly boys, of mothers with depressive symptoms may be negatively influenced by depressive symptoms.展开更多
Background: The healthy bond that develops prenatally between the mother and her infant is important for the neuropsychological development and development of the child. In stressful situations and mental disorders, t...Background: The healthy bond that develops prenatally between the mother and her infant is important for the neuropsychological development and development of the child. In stressful situations and mental disorders, the development of this bond is inhibited. With this study, an attempt is made to investigate whether the COVID-19 pandemic affected the development of the mother-infant bond. Methods: We have searched in the databases, PubMed, Google Scholar, PsycINFO, from July to October 2023 and we have found 18 related articles. Results: Most studies supported a lower mother-infant attachment during the pandemic period. We also found increased rates of depressive symptoms, anxiety and post-traumatic stress during the pandemic. Conclusions: The period of the pandemic and the psychological factors were the right conditions for the reduced development of the mother-infant bond. In epidemiological outbreaks, the mental health of the mother and her relationship with the infant should be a priority for perinatal care professionals.展开更多
Objective To determine the hepatitis B immunoprophylactic failure rate in infants born to hepatitis B virus （HBV） infected mothers and to characterize HBV genes. Methods HBV-serological testing was conducted for pre...Objective To determine the hepatitis B immunoprophylactic failure rate in infants born to hepatitis B virus （HBV） infected mothers and to characterize HBV genes. Methods HBV-serological testing was conducted for pregnant women and infants. The complete genomes of 30 HBV isolates were sequenced, and genetic characteristics were analyzed using MEGA 5 software. Results The immunoprophylactic failure rate for infants who had completed the scheduled hepatitis B vaccination program was 5.76% （32/556）. High sequence homology （99.8%-100%） was observed in 8 of the 10 mother-infant pairs. We identified 19 subgenotype C2 strains, 9 subgenotype B2 strains, and 2 subgenotype Cl strains. Three serotypes were detected： adr （19/30）, adw （9/30）, and ayw （2/30）. The frequency of amino acid mutation of the ＇a＇ determinant region was 16.67% （5/30）, including that of Q129H, F134Y,S136Y, and G145E. We detected 67 amino acid mutations in the basal core promoter, precore, and core regions of the genome. Conclusion The immunoprophylactic failure rate in infants born to HBV-infected mothers is low in the regions of China examined during this study. Moreover, HBV mutation in the ＇a＇ determinant region could not account for immunoprophylactic failure for all infants.展开更多
Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-nfant transmission of hepatitis B virus (...Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-nfant transmission of hepatitis B virus (HBV), but the duration of immune efficacy of RYHB vaccine is not clear. This study indicates the long-term efficacy for the prevention of mother-infant transmission of HBV. One hundred and six neonates born to HBsAg-arrier mothers with HBeAg positive were randomly divided into two groups, one receiving 20 μg per dose of RYHB vaccine and the another receiving 20 μg per dose of PHB vaccine on the day of birth, at 1 month and at 6 months (three times). Physical examination and blood tests were performed for all infants at 6, 12, 24, 36, 48 and 60 months of age. The results showed that the protective efficacies at 6, 12, 24, 36, 48 and 60 months were 67%, 75%, 63%, 62%, 57% and 56%, respectively for the RYHB vaccine group and 58%, 76%, 51%, 41%, 24% and 18%, respectively for the PHB vaccine group. The protective efficacy was notably significant in the last two years. The study indicates that the duration of protective efficacy is over 5 years with RYHB vaccine, being longer than that of PHB vaccine. These recipients of RYHB vaccine showed no side effects, and the vaccine is regarded as safe and effective.展开更多
生命早期由于免疫系统的不成熟,新生儿和幼儿更容易受到感染。I型干扰素(type I interferons,IFN-I)在抗病毒过程中发挥重要作用。其中干扰素β(interferon-β,IFN-β)在IFN-I家族中更专注于稳定的保护性免疫,防止感染和炎症。研究表明...生命早期由于免疫系统的不成熟,新生儿和幼儿更容易受到感染。I型干扰素(type I interferons,IFN-I)在抗病毒过程中发挥重要作用。其中干扰素β(interferon-β,IFN-β)在IFN-I家族中更专注于稳定的保护性免疫,防止感染和炎症。研究表明,部分益生菌能够调节IFN-β的分泌,且其抗感染能力表现出菌株特异性。同时,由于母婴源益生菌在婴幼儿中具有更高的生态适应性,该文旨在通过体外益生特性评价和小鼠骨髓源树突状细胞(bone marrow-derived dendritic cells,BMDC)模型筛选具有婴幼儿肠道适应性和潜在免疫保护作用的母婴源益生菌。结果显示,13株母婴源益生菌中,戊糖片球菌CCFM1443在BMDC模型中展现出最强的免疫调节能力,促进BMDC分泌IFN-β的质量浓度高达174.13 pg/mL。体外益生特性评价结果表明,戊糖片球菌CCFM1443具有良好的益生特性:代时最短(G=2.03 h),表明其生长速率快;在模拟肠液条件下的存活率最高,存活率为30.06%;具有较好的抗菌活性,对3种致病菌有抑制作用;肠道黏附能力仅次于3株格氏乳杆菌,黏附率为11.02%。此外,进一步细胞实验显示,戊糖片球菌CCFM1443热杀菌对不同周龄来源的BMDC调节效果优于活菌,表明戊糖片球菌CCFM1443的潜在应用范围较为广泛。研究结果为后期开发提高婴幼儿免疫水平的母婴益生菌产品提供了理论基础。展开更多
BACKGROUND Perinatal anxiety disorder is the main problem affecting mother-infant bonding.Though the impact of perinatal anxiety in primiparous women on the motherinfant relationship is well established,appropriate in...BACKGROUND Perinatal anxiety disorder is the main problem affecting mother-infant bonding.Though the impact of perinatal anxiety in primiparous women on the motherinfant relationship is well established,appropriate interventions need to be explored.AIM To explore the synergistic intervention effect of mindfulness-based stress reduction combined with cognitive behavioral therapy(CBT)on perinatal anxiety disorders and mother-infant bonding in primiparas.METHODS A total of 150 primiparas with perinatal anxiety disorders admitted to the hospital from January 2020 to October 2024 were selected and divided into two groups according to the random number method.The control group(n=75)received CBT,and the observation group(n=75)received mindfulness-based stress reduction combined with CBT.The anxiety and depressive emotions,as well as the mother-infant emotional bonding situation,were compared between the two groups.RESULTS After the intervention,the anxiety and depressive states in the observation group were lower than those in the control group(P<0.05).The mother-infant bonding(sense of pleasure,recognition,understanding,and love)in the observation group was higher than that in the control group,and the role adaptation ability was also higher than in the control group(P<0.05).CONCLUSION Mindfulness-based stress reduction combined with CBT can reduce perinatal anxiety disorders in primiparas,promote mother-infant bonding,and improve their ability to adapt to the mother role.展开更多
目的探讨早产儿重症监护病房(neonatal intensive care unit,NICU)早产儿母亲家庭抗逆力的变化轨迹及其影响因素,为制订个性化护理干预方案提供理论依据。方法采用便利抽样法,选取2023年9月至2024年5月泰安市中心医院和泰安市妇幼保健院...目的探讨早产儿重症监护病房(neonatal intensive care unit,NICU)早产儿母亲家庭抗逆力的变化轨迹及其影响因素,为制订个性化护理干预方案提供理论依据。方法采用便利抽样法,选取2023年9月至2024年5月泰安市中心医院和泰安市妇幼保健院NICU收治的264例早产儿及其母亲作为研究对象,分别在早产儿入院时(T0)、矫正胎龄40周(T1)、矫正月龄1月龄(T2)、矫正月龄3月龄(T3)时调查其母亲的家庭抗逆力水平,使用潜类别增长混合模型识别家庭抗逆力的轨迹类别,采用logistic回归分析不同轨迹类别的影响因素。结果NICU早产儿母亲T0~T3时间点家庭抗逆力得分分别为(126.34±19.95)分、(127.92±18.71)分、(131.55±20.04)分、(134.77±18.85)分,差异具有统计学意义(P<0.01);共识别出3种抗逆力轨迹类别,根据其特征分别命名为低水平抗逆力组、中水平抗逆力组和高水平抗逆力组。单因素分析显示,胎龄、出生体质量、喂养方式、母亲文化程度、家庭结构、分娩方式、产次、疾病不确定感与家庭抗逆力轨迹类别有关(P<0.05);多因素logistic回归分析显示,胎龄、喂养方式、母亲产次、疾病不确定感是家庭抗逆力轨迹类别的主要影响因素(P<0.05)。结论NICU早产儿母亲家庭抗逆力的变化轨迹存在异质性,医护人员应根据家庭抗逆力的变化轨迹及其影响因素,对早产儿母亲实施阶段性及特异性的护理干预措施。展开更多
文摘Objective:To analyze the impact of maternal-infant separation on the physical and mental state of high-risk pregnancy patients and explore the clinical efficacy of targeted nursing interventions.Methods:A total of 80 high-risk pregnancy patients treated in our hospital from January 2023 to January 2024 were selected as the study subjects.These patients were randomly divided into an observation group and a control group(40 cases each)using a random number table.The control group received routine high-risk pregnancy nursing care,while the observation group received specialized maternal-infant separation nursing interventions in addition to routine care.The psychological and physiological states and nursing satisfaction of the two groups were compared before and after the intervention.Results:The SAS scores,SDS scores,and sleep quality scores of the observation group were significantly lower than those of the control group,with statistically significant differences(p<0.05).The incidence of postpartum hemorrhage in the observation group was significantly lower than that in the control group,and the initiation time of lactation was significantly earlier than that in the control group,with both differences being statistically significant(p<0.05).The nursing satisfaction of the observation group was significantly higher than that of the control group(80%vs.32/40),with a statistically significant difference(p<0.05).Conclusion:Maternal-infant separation exacerbates anxiety and depression in high-risk pregnancy patients,reduces sleep quality,increases the risk of postpartum hemorrhage,and delays the initiation of lactation.Specialized nursing interventions for maternal-infant separation can improve the physical and mental state of high-risk pregnancy patients,reduce the incidence of postpartum complications,and enhance nursing satisfaction,making them worthy of clinical application and promotion.
文摘Objectives: Since it has been suggested that moderate alcohol drinking would increase insulin sensitivity, which could benefit Gestational Diabetes Mellitus (GDM), the study aimed at evaluating alcohol consumption during pregnancy, and seeing whether this consumption influences GDM detection and maternal/perinatal outcomes. Study design: Women with already known diabetes and those with multiple pregnancy were excluded. All other pregnant women attending antenatal care unit of the university clinics, Kinshasa, DR Congo during the period from 1 March throughout 31 October 2010, were invited at 24-week gestation to enroll in O’Sullivan blood glucose testing and if eligible in 100-gram oral glucose tolerance test. Alcohol consumption, risk factors for GDM, and general characteristics such as age, parity, gestity, BMI, fat mass were registered. Diagnosed GDM was first treated with diet and exercise, thereafter with Metformin, and if necessary with insulin. For other (normal) women data remained blinded until confinement. Maternal and infant’s adverse outcomes such as maternal urinary infection, preeclampsia, cesarean section, intrauterine growth retardation, birth weight percentile 90 in our milieu), Apgar score at the first minute < 7, shoulder dystocia or other birth injury, neonatal hypoglycemia and fetal alcohol syndrome (FAS) were compared and analyzed according to GDM diagnosis as well to alcohol status. Results: Up to 240 pregnant women accepted to enroll into the study. Alcohol consumption concerned 78 (32.5%) of the women, most of them (61 = 25.42%) being heavy consumers. Risk factors for GDM and Physical and blood glucose characteristics were alike (p not significant) in both consumers and non consumers, except for history of HTA in the family that was significantly more frequent (p = 0.02) among drinkers. GDM’s prevalence was 9%. No adverse outcome was more prominent in any subgroup, except Apgar score < 7 at the first minute that was more frequent (p = 0.038) among neonates of GDM mothers. No FAS, neither shoulder dystocia nor neonatal hypoglycemia were diagnosed. When alcohol status was considered, Birthweight ≥ 3800 g was found more frequent (p = 0.0284) in alcohol consumers than in abstainers. Risk of this outcome was three times higher when history of family hypertension was present (odds ratio 2.694;CI: 0.536 - 13.544). Conclusions: The prevalence of alcohol consumption by pregnant women of our series (32.5%) seems not to impact the detection of GDM (9%). FAS was not diagnosed. Lack of significant differences in adverse outcomes between GDM and non GDM could be attributed to huge follow-up of GDM women. Influence of alcohol consumption on birth weight mostly in setting of familial history of hypertension remains to be addressed.
基金supported by the National Natural Science Foundation of China(32272316)Beijing Innovation Team of Livestock Industry Technology System(BAIC05-2022)Guangxi Science and Technology Project(AD20297088).
文摘Nutrients in human milk,including minerals,relate growth and development of breast-fed infants.Tibetan mother-infant dyads possess unique characteristics on early nutrition due to their featured long-lasting lifestyle.This study longitudinally investigated the relationship between the mineral composition in human milk and the Z-scores of infants among Tibetan mother-infant dyads during their first 6 months postpartum through a prospective cohort study.The results show that the minerals of Na,Mg,K,Ca,Cu,Zn,and Se were of higher levels in colostrum than other lactation stages.Several minerals were below the recommended values for infants according to Chinese dietary guidelines.Besides,a large proportion of infant Z-scores were below-2 as lactation period continued.Multivariate statistical analysis revealed that classifications and correlations in varying degrees were observed between minerals in human milk and infant Z-scores.These findings will be advantageous for research upon Chinese early nutrition and progress of tailor-made infant formula.
文摘Aim: To investigate the impact of postnatal depressive symptoms and infant sex on perceived and observed mother-infant interaction among rural Bangladeshi women. Methods: Fifty women with depressive symptoms and their infants at 2 - 3 months were compared with 50 women without depressed symptoms and their infants, matched on geographic areas, parity and infant sex. The Edinburgh Postnatal Depression Scale assessed depressive symptoms, the Postpartum Bonding Questionnaire assessed the mother’s perception of bonding with the infant and mother-infant interactions were videotaped and analyzed with the Global Rating Scale. Results: Mothers with depressive symptoms were poorer, were less educated and rated lower infant bonding than mothers without depressive symptoms (p = 0.03), yet objective observation revealed no difference between the two groups regarding maternal interactive behavior (p = 0.57). However, infants, particularly boys (p = 0.002), of mothers with depressive symptoms fretted more in mother-infant interaction than infants of mothers without depressive symptoms (p = 0.009). Conclusion: Although mothers with depressive symptoms did not show less sensitivity in interactive behavior at 2 - 3 months than those without depressive symptoms, our results indicate that infants, particularly boys, of mothers with depressive symptoms may be negatively influenced by depressive symptoms.
文摘Background: The healthy bond that develops prenatally between the mother and her infant is important for the neuropsychological development and development of the child. In stressful situations and mental disorders, the development of this bond is inhibited. With this study, an attempt is made to investigate whether the COVID-19 pandemic affected the development of the mother-infant bond. Methods: We have searched in the databases, PubMed, Google Scholar, PsycINFO, from July to October 2023 and we have found 18 related articles. Results: Most studies supported a lower mother-infant attachment during the pandemic period. We also found increased rates of depressive symptoms, anxiety and post-traumatic stress during the pandemic. Conclusions: The period of the pandemic and the psychological factors were the right conditions for the reduced development of the mother-infant bond. In epidemiological outbreaks, the mental health of the mother and her relationship with the infant should be a priority for perinatal care professionals.
基金supported by the Chinese Twelfth Five-Year Plan,a major science and technology program for hepatitis(Grant Number:2012ZX10002001)
文摘Objective To determine the hepatitis B immunoprophylactic failure rate in infants born to hepatitis B virus （HBV） infected mothers and to characterize HBV genes. Methods HBV-serological testing was conducted for pregnant women and infants. The complete genomes of 30 HBV isolates were sequenced, and genetic characteristics were analyzed using MEGA 5 software. Results The immunoprophylactic failure rate for infants who had completed the scheduled hepatitis B vaccination program was 5.76% （32/556）. High sequence homology （99.8%-100%） was observed in 8 of the 10 mother-infant pairs. We identified 19 subgenotype C2 strains, 9 subgenotype B2 strains, and 2 subgenotype Cl strains. Three serotypes were detected： adr （19/30）, adw （9/30）, and ayw （2/30）. The frequency of amino acid mutation of the ＇a＇ determinant region was 16.67% （5/30）, including that of Q129H, F134Y,S136Y, and G145E. We detected 67 amino acid mutations in the basal core promoter, precore, and core regions of the genome. Conclusion The immunoprophylactic failure rate in infants born to HBV-infected mothers is low in the regions of China examined during this study. Moreover, HBV mutation in the ＇a＇ determinant region could not account for immunoprophylactic failure for all infants.
文摘Recombinant DNA Yeast-Derived Hepatitis B Vaccine (RYHB vaccine) is comparable to and can replace Plasma-Derived Hepatitis B Vaccine (PHB vaccine) for the prevention of mother-nfant transmission of hepatitis B virus (HBV), but the duration of immune efficacy of RYHB vaccine is not clear. This study indicates the long-term efficacy for the prevention of mother-infant transmission of HBV. One hundred and six neonates born to HBsAg-arrier mothers with HBeAg positive were randomly divided into two groups, one receiving 20 μg per dose of RYHB vaccine and the another receiving 20 μg per dose of PHB vaccine on the day of birth, at 1 month and at 6 months (three times). Physical examination and blood tests were performed for all infants at 6, 12, 24, 36, 48 and 60 months of age. The results showed that the protective efficacies at 6, 12, 24, 36, 48 and 60 months were 67%, 75%, 63%, 62%, 57% and 56%, respectively for the RYHB vaccine group and 58%, 76%, 51%, 41%, 24% and 18%, respectively for the PHB vaccine group. The protective efficacy was notably significant in the last two years. The study indicates that the duration of protective efficacy is over 5 years with RYHB vaccine, being longer than that of PHB vaccine. These recipients of RYHB vaccine showed no side effects, and the vaccine is regarded as safe and effective.
文摘BACKGROUND Perinatal anxiety disorder is the main problem affecting mother-infant bonding.Though the impact of perinatal anxiety in primiparous women on the motherinfant relationship is well established,appropriate interventions need to be explored.AIM To explore the synergistic intervention effect of mindfulness-based stress reduction combined with cognitive behavioral therapy(CBT)on perinatal anxiety disorders and mother-infant bonding in primiparas.METHODS A total of 150 primiparas with perinatal anxiety disorders admitted to the hospital from January 2020 to October 2024 were selected and divided into two groups according to the random number method.The control group(n=75)received CBT,and the observation group(n=75)received mindfulness-based stress reduction combined with CBT.The anxiety and depressive emotions,as well as the mother-infant emotional bonding situation,were compared between the two groups.RESULTS After the intervention,the anxiety and depressive states in the observation group were lower than those in the control group(P<0.05).The mother-infant bonding(sense of pleasure,recognition,understanding,and love)in the observation group was higher than that in the control group,and the role adaptation ability was also higher than in the control group(P<0.05).CONCLUSION Mindfulness-based stress reduction combined with CBT can reduce perinatal anxiety disorders in primiparas,promote mother-infant bonding,and improve their ability to adapt to the mother role.
文摘目的探讨早产儿重症监护病房(neonatal intensive care unit,NICU)早产儿母亲家庭抗逆力的变化轨迹及其影响因素,为制订个性化护理干预方案提供理论依据。方法采用便利抽样法,选取2023年9月至2024年5月泰安市中心医院和泰安市妇幼保健院NICU收治的264例早产儿及其母亲作为研究对象,分别在早产儿入院时(T0)、矫正胎龄40周(T1)、矫正月龄1月龄(T2)、矫正月龄3月龄(T3)时调查其母亲的家庭抗逆力水平,使用潜类别增长混合模型识别家庭抗逆力的轨迹类别,采用logistic回归分析不同轨迹类别的影响因素。结果NICU早产儿母亲T0~T3时间点家庭抗逆力得分分别为(126.34±19.95)分、(127.92±18.71)分、(131.55±20.04)分、(134.77±18.85)分,差异具有统计学意义(P<0.01);共识别出3种抗逆力轨迹类别,根据其特征分别命名为低水平抗逆力组、中水平抗逆力组和高水平抗逆力组。单因素分析显示,胎龄、出生体质量、喂养方式、母亲文化程度、家庭结构、分娩方式、产次、疾病不确定感与家庭抗逆力轨迹类别有关(P<0.05);多因素logistic回归分析显示,胎龄、喂养方式、母亲产次、疾病不确定感是家庭抗逆力轨迹类别的主要影响因素(P<0.05)。结论NICU早产儿母亲家庭抗逆力的变化轨迹存在异质性,医护人员应根据家庭抗逆力的变化轨迹及其影响因素,对早产儿母亲实施阶段性及特异性的护理干预措施。
