目的:探讨性别差异对急性A型主动脉夹层(acute type A aortic dissection,ATAAD)患者术后住院期间(手术后30d)死亡的影响。方法:回顾性分析2015年11月至2020年12月于首都医科大学附属北京安贞医院心脏外科因ATAAD接受急诊手术的432例患...目的:探讨性别差异对急性A型主动脉夹层(acute type A aortic dissection,ATAAD)患者术后住院期间(手术后30d)死亡的影响。方法:回顾性分析2015年11月至2020年12月于首都医科大学附属北京安贞医院心脏外科因ATAAD接受急诊手术的432例患者(年龄> 18岁)的临床资料。根据性别将患者分为男性组和女性组。采用单因素和多因素Logistic回归分析研究性别与术后30天内死亡的关系。结果:纳入的患者中,男性340例(78.7%),平均年龄为(46.4±10.6)岁;女性92例(21.3%),平均年龄为(51.5±11.7)岁。术后30天内,共45例(10.4%)患者死亡,其中女性组死亡15例(16.3%),男性组死亡30例(8.8%),两组间差异有统计学意义(P=0.037)。多因素Logistic回归分析显示性别与ATAAD患者术后30天内死亡无相关性(OR=0.792,95%CI:0.311~2.014,P=0.624)。结论:在ATAAD患者中,性别差异对手术后30天内的死亡没有影响。展开更多
AIM:To evaluate the applicability of AIMS65 scores in predicting outcomes of peptic ulcer bleeding.METHODS:This was a retrospective study in a single center between January 2006 and December 2011.We enrolled 522 patie...AIM:To evaluate the applicability of AIMS65 scores in predicting outcomes of peptic ulcer bleeding.METHODS:This was a retrospective study in a single center between January 2006 and December 2011.We enrolled 522 patients with upper gastrointestinal haemorrhage who visited the emergency room.Highrisk patients were regarded as those who had rebleeding within 30 d from the first endoscopy as well as those who died within 30 d of visiting the Emergency room.A total of 149 patients with peptic ulcer bleeding were analysed,and the AIMS65 score was used to retrospectively predict the high-risk patients.RESULTS:A total of 149 patients with peptic ulcer bleeding were analysed.The poor outcome group comprised 28 patients[male:23(82.1%)vs female:5(10.7%)]while the good outcome group included 121patients[male:93(76.9%)vs female:28(23.1%)].The mean age in each group was not significantly different.The mean serum albumin levels in the poor outcome group were slightly lower than those in the good outcome group(P=0.072).For the prediction of poor outcome,the AIMS65 score had a sensitivity of35.5%(95%CI:27.0-44.8)and a specificity of 82.1%(95%CI:63.1-93.9)at a score of 0.The AIMS65 score was insufficient for predicting outcomes in peptic ulcer bleeding(area under curve=0.571;95%CI:0.49-0.65).CONCLUSION:The AIMS65 score may therefore not be suitable for predicting clinical outcomes in peptic ulcer bleeding.Low albumin levels may be a risk factor associated with high mortality in peptic ulcer bleeding.展开更多
文摘目的:探讨性别差异对急性A型主动脉夹层(acute type A aortic dissection,ATAAD)患者术后住院期间(手术后30d)死亡的影响。方法:回顾性分析2015年11月至2020年12月于首都医科大学附属北京安贞医院心脏外科因ATAAD接受急诊手术的432例患者(年龄> 18岁)的临床资料。根据性别将患者分为男性组和女性组。采用单因素和多因素Logistic回归分析研究性别与术后30天内死亡的关系。结果:纳入的患者中,男性340例(78.7%),平均年龄为(46.4±10.6)岁;女性92例(21.3%),平均年龄为(51.5±11.7)岁。术后30天内,共45例(10.4%)患者死亡,其中女性组死亡15例(16.3%),男性组死亡30例(8.8%),两组间差异有统计学意义(P=0.037)。多因素Logistic回归分析显示性别与ATAAD患者术后30天内死亡无相关性(OR=0.792,95%CI:0.311~2.014,P=0.624)。结论:在ATAAD患者中,性别差异对手术后30天内的死亡没有影响。
基金Supported by Catholic Research Coordinating Center of the Korea health 21 R and D Project,No.A070001Ministry of Health and Welfare South Korea
文摘AIM:To evaluate the applicability of AIMS65 scores in predicting outcomes of peptic ulcer bleeding.METHODS:This was a retrospective study in a single center between January 2006 and December 2011.We enrolled 522 patients with upper gastrointestinal haemorrhage who visited the emergency room.Highrisk patients were regarded as those who had rebleeding within 30 d from the first endoscopy as well as those who died within 30 d of visiting the Emergency room.A total of 149 patients with peptic ulcer bleeding were analysed,and the AIMS65 score was used to retrospectively predict the high-risk patients.RESULTS:A total of 149 patients with peptic ulcer bleeding were analysed.The poor outcome group comprised 28 patients[male:23(82.1%)vs female:5(10.7%)]while the good outcome group included 121patients[male:93(76.9%)vs female:28(23.1%)].The mean age in each group was not significantly different.The mean serum albumin levels in the poor outcome group were slightly lower than those in the good outcome group(P=0.072).For the prediction of poor outcome,the AIMS65 score had a sensitivity of35.5%(95%CI:27.0-44.8)and a specificity of 82.1%(95%CI:63.1-93.9)at a score of 0.The AIMS65 score was insufficient for predicting outcomes in peptic ulcer bleeding(area under curve=0.571;95%CI:0.49-0.65).CONCLUSION:The AIMS65 score may therefore not be suitable for predicting clinical outcomes in peptic ulcer bleeding.Low albumin levels may be a risk factor associated with high mortality in peptic ulcer bleeding.
