Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-...Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-aged/older stroke patients hospitalized in the Department of Neurological Rehabilitation, China Rehabilitation Research Center, Capital Medical University, China from February 2014 to May 2015. Results demonstrated that hemorrhagic stroke （59.6%） was the primary stroke type found in the young group, while ischemic stroke （60.0%） was the main type detected in the middle-aged/older group. Compared with older stroke patients, education level and incidence of hyperhomocysteinemia were higher in younger stroke patients, whereas, incidences of hypertension, diabetes, and heart disease were lower. The average length of hospital stay was longer in the young group than in the middle-aged/older group. The main risk factors observed in the young stroke patients were hypertension, drinking, smoking, hyperlipidemia, hyperhomocysteinemia, diabetes, previous history of stroke, and heart disease. The most accepted rehabilitation program consisted of physiotherapy, occupational therapy, speech therapy, acupuncture and moxibustion. Average rehabilitation training time was 2.5 hours/day. Barthel Index and modified Rankin Scale scores were increased at discharge. Six months after discharge, the degree of occupational and economic satisfaction declined, and there were no changes in family life satisfaction. The degrees of other life satisfaction （such as friendship） improved. The degree of disability and functional status improved significantly in young stroke patients after professional rehabilitation, but the number of patients who returned to society within 6 months after stroke was still small.展开更多
Background and Objectives:Sarcopenia is prevalent in patients with stroke.However,the relationship between sarcopenia and poor functional outcome of patients with acute stroke remains unknown.A systematic review and m...Background and Objectives:Sarcopenia is prevalent in patients with stroke.However,the relationship between sarcopenia and poor functional outcome of patients with acute stroke remains unknown.A systematic review and meta-analysis was performed to evaluate the above association.Methods and Study Design:Observational studies which evaluated the influence of sarcopenia on functional outcome in patients with acute stroke were retrieved by search the PubMed,Embase,Cochrane Library,and Web of Science databases.A poor functional outcome was defined as modified Rankin scale(mRS)of two or more points during follow-up.Two authors independently collected the data of study characteristics and outcomes.A random-effects model was used to pool the results via incorporating the influence of possible between-study heterogeneity.Results:Nine datasets from seven cohort studies contributed to the meta-analysis.A total of 1774 patients with stroke were included,and 481(27.1%)of them had sarcopenia.Compared to patients without sarcopenia,those with sarcopenia were associated with a higher risk of poor functional outcome during follow-up duration up to 6 months after stroke onset(odds ratio:2.42,95%confidence interval:1.76 to 3.33,p<0.001)with mild heterogeneity(I^(2)=23%).Subgroup analyses according to study design(prospective versus retrospective),sex of the patient,type of stroke(ischemic or mixed),diagnostic methods for sarcopenia,follow-up duration and cutoff scores for mRS showed consistent results(p for subgroup analyses all>0.05).Conclusions:Sarcopenia may be associated with poor functional outcome in patients with acute stroke.展开更多
基金supported by the Special Fund of Basic Scientific Research Service Fee of Central Public Welfare Scientif ic Research Institute of China,No.2014CZ-13
文摘Young stroke patients have a strong desire to return to the society, but few studies have been conducted on their rehabilitation training items, intensity, and prognosis. We analyzed clinical data of young and middle-aged/older stroke patients hospitalized in the Department of Neurological Rehabilitation, China Rehabilitation Research Center, Capital Medical University, China from February 2014 to May 2015. Results demonstrated that hemorrhagic stroke （59.6%） was the primary stroke type found in the young group, while ischemic stroke （60.0%） was the main type detected in the middle-aged/older group. Compared with older stroke patients, education level and incidence of hyperhomocysteinemia were higher in younger stroke patients, whereas, incidences of hypertension, diabetes, and heart disease were lower. The average length of hospital stay was longer in the young group than in the middle-aged/older group. The main risk factors observed in the young stroke patients were hypertension, drinking, smoking, hyperlipidemia, hyperhomocysteinemia, diabetes, previous history of stroke, and heart disease. The most accepted rehabilitation program consisted of physiotherapy, occupational therapy, speech therapy, acupuncture and moxibustion. Average rehabilitation training time was 2.5 hours/day. Barthel Index and modified Rankin Scale scores were increased at discharge. Six months after discharge, the degree of occupational and economic satisfaction declined, and there were no changes in family life satisfaction. The degrees of other life satisfaction （such as friendship） improved. The degree of disability and functional status improved significantly in young stroke patients after professional rehabilitation, but the number of patients who returned to society within 6 months after stroke was still small.
文摘Background and Objectives:Sarcopenia is prevalent in patients with stroke.However,the relationship between sarcopenia and poor functional outcome of patients with acute stroke remains unknown.A systematic review and meta-analysis was performed to evaluate the above association.Methods and Study Design:Observational studies which evaluated the influence of sarcopenia on functional outcome in patients with acute stroke were retrieved by search the PubMed,Embase,Cochrane Library,and Web of Science databases.A poor functional outcome was defined as modified Rankin scale(mRS)of two or more points during follow-up.Two authors independently collected the data of study characteristics and outcomes.A random-effects model was used to pool the results via incorporating the influence of possible between-study heterogeneity.Results:Nine datasets from seven cohort studies contributed to the meta-analysis.A total of 1774 patients with stroke were included,and 481(27.1%)of them had sarcopenia.Compared to patients without sarcopenia,those with sarcopenia were associated with a higher risk of poor functional outcome during follow-up duration up to 6 months after stroke onset(odds ratio:2.42,95%confidence interval:1.76 to 3.33,p<0.001)with mild heterogeneity(I^(2)=23%).Subgroup analyses according to study design(prospective versus retrospective),sex of the patient,type of stroke(ischemic or mixed),diagnostic methods for sarcopenia,follow-up duration and cutoff scores for mRS showed consistent results(p for subgroup analyses all>0.05).Conclusions:Sarcopenia may be associated with poor functional outcome in patients with acute stroke.
