Graduate course teaching plays an irreplaceable role in knowledge mastery,skill enhancement,and quality cultivation of graduate students.This paper addresses current issues in graduate course teaching,such as ambiguou...Graduate course teaching plays an irreplaceable role in knowledge mastery,skill enhancement,and quality cultivation of graduate students.This paper addresses current issues in graduate course teaching,such as ambiguous objectives,formulaic content,formalistic operation,and oversimplified evaluation.It proposes corresponding solutions with the hope of steering graduate course teaching back to its original purpose and realizing its true significance.展开更多
AIM:To describe a case of aqueous misdirection complicated by subsequent persistent choroidal effusions following implantation of a Preserflo Micro Shunt(PMS)device to treat advanced closed angle glaucoma.METHODS:A 67...AIM:To describe a case of aqueous misdirection complicated by subsequent persistent choroidal effusions following implantation of a Preserflo Micro Shunt(PMS)device to treat advanced closed angle glaucoma.METHODS:A 67-year-old caucasian female with advanced primar y angle-closure glaucoma on four medications with an intraocular pressure(IOP)of 26 mm Hg was listed for a PMS insertion with mitomycin C(MMC).RESULTS:Past ocular history was significant for pseudophakia and previous yttrium aluminum garnet(YAG)peripheral iridotomy.Surgery was uneventful but on the first postoperative day,she developed aqueous misdirection complicated by subsequent development of persistent uveal effusions.Conventional treatment strategies including atropine drops,YAG hyaloidotomy and choroidal effusion drainage proved ineffective.A combination of oral steroids and pars plana vitrectomy(PPV)along with an irido-zonulohyloidectomy(IZH)proved efficacious.CONCLUSION:To the best of the author’s knowledge,this is the first published case of aqueous misdirection complicated with the presence of significant,unresolving choroidal effusions,highlighting the possibility and sequelae of comorbid pathology in nanophthalmic eyes.展开更多
Background To report the incidence and clinical characteristics of aqueous misdirection(AM)after glaucoma surgery in Chinese patients with primary angle-closure glaucoma.Methods Medical records of all patients diagnos...Background To report the incidence and clinical characteristics of aqueous misdirection(AM)after glaucoma surgery in Chinese patients with primary angle-closure glaucoma.Methods Medical records of all patients diagnosed with primary angle-closure glaucoma who underwent glaucoma surgery in the Eye Hospital of Wenzhou Medical University between January 2012 and December 2021 were retrospectively reviewed.Cases of AM were identified through a keyword-based search.The incidence of AM was calculated.Demographic and clinical characteristics of the AM patients were also described.Results A total of 5044 eyes with primary angle-closure glaucoma were included(mean age 65.81±9.96 years,68.11%women).Thirty-eight eyes developed AM,presenting an overall incidence of 0.75%.The mean time interval between surgery and first record of AM diagnosis was 2.57±5.24 months(range,0 day to 24 months).The incidence of AM was significantly higher in patients aged≤40 years(21.28%)and those aged 40–50 years(3.32%),compared to those>50 years(0.42%)(P<0.001).AM developed much more frequently among patients with chronic angle-closure glaucoma(1.30%),compared to those with acute angle-closure glaucoma(0.32%,P<0.001).Eleven eyes(0.37%)developed AM following non-filtering surgery compared to 24 eyes(2.27%)after filtering surgery(P<0.001).Conclusion The incidence of AM after glaucoma surgery was 0.75%in Chinese patients with primary angle closure glaucoma.Younger age,chronic angle-closure glaucoma,and undergoing filtering surgery,were identified as associated risk factors for developing AM.Phacoemulsification may have less risk of developing AM compared to filtering surgery.展开更多
基金Research on the Dilemma and Path of Cultivating Medical Students’Professionalism in the Perspective of Newcomers of the Times(Y202354086)。
文摘Graduate course teaching plays an irreplaceable role in knowledge mastery,skill enhancement,and quality cultivation of graduate students.This paper addresses current issues in graduate course teaching,such as ambiguous objectives,formulaic content,formalistic operation,and oversimplified evaluation.It proposes corresponding solutions with the hope of steering graduate course teaching back to its original purpose and realizing its true significance.
文摘AIM:To describe a case of aqueous misdirection complicated by subsequent persistent choroidal effusions following implantation of a Preserflo Micro Shunt(PMS)device to treat advanced closed angle glaucoma.METHODS:A 67-year-old caucasian female with advanced primar y angle-closure glaucoma on four medications with an intraocular pressure(IOP)of 26 mm Hg was listed for a PMS insertion with mitomycin C(MMC).RESULTS:Past ocular history was significant for pseudophakia and previous yttrium aluminum garnet(YAG)peripheral iridotomy.Surgery was uneventful but on the first postoperative day,she developed aqueous misdirection complicated by subsequent development of persistent uveal effusions.Conventional treatment strategies including atropine drops,YAG hyaloidotomy and choroidal effusion drainage proved ineffective.A combination of oral steroids and pars plana vitrectomy(PPV)along with an irido-zonulohyloidectomy(IZH)proved efficacious.CONCLUSION:To the best of the author’s knowledge,this is the first published case of aqueous misdirection complicated with the presence of significant,unresolving choroidal effusions,highlighting the possibility and sequelae of comorbid pathology in nanophthalmic eyes.
基金supported by the Program for Zhejiang Leading Talent of S&T Innovation(Grant No.2021R52012)the National Key Research and Development Project of China(Grant No.2020YFC2008200)+2 种基金Key Research and Development Projects of Zhejiang Province(Grant No.2022C03112)the Basic Scientific Research Program of Wenzhou(Grant No.Y2020365)Key Innovation and Guidance Program of the Eye Hospital,School of Ophthalmology and Optometry,Wenzhou Medical University(Grant No.YNZD2201903).
文摘Background To report the incidence and clinical characteristics of aqueous misdirection(AM)after glaucoma surgery in Chinese patients with primary angle-closure glaucoma.Methods Medical records of all patients diagnosed with primary angle-closure glaucoma who underwent glaucoma surgery in the Eye Hospital of Wenzhou Medical University between January 2012 and December 2021 were retrospectively reviewed.Cases of AM were identified through a keyword-based search.The incidence of AM was calculated.Demographic and clinical characteristics of the AM patients were also described.Results A total of 5044 eyes with primary angle-closure glaucoma were included(mean age 65.81±9.96 years,68.11%women).Thirty-eight eyes developed AM,presenting an overall incidence of 0.75%.The mean time interval between surgery and first record of AM diagnosis was 2.57±5.24 months(range,0 day to 24 months).The incidence of AM was significantly higher in patients aged≤40 years(21.28%)and those aged 40–50 years(3.32%),compared to those>50 years(0.42%)(P<0.001).AM developed much more frequently among patients with chronic angle-closure glaucoma(1.30%),compared to those with acute angle-closure glaucoma(0.32%,P<0.001).Eleven eyes(0.37%)developed AM following non-filtering surgery compared to 24 eyes(2.27%)after filtering surgery(P<0.001).Conclusion The incidence of AM after glaucoma surgery was 0.75%in Chinese patients with primary angle closure glaucoma.Younger age,chronic angle-closure glaucoma,and undergoing filtering surgery,were identified as associated risk factors for developing AM.Phacoemulsification may have less risk of developing AM compared to filtering surgery.
