This study examined the relationship between inclusive leadership and authenticity at work in racial minority groups of South Africa,taking into account the mediating role of psychological safety and the moderator rol...This study examined the relationship between inclusive leadership and authenticity at work in racial minority groups of South Africa,taking into account the mediating role of psychological safety and the moderator role of gender,in that relationship.The sample was composed of 94 employees predominantly working in the professional services sector from South Africa(41.5%females;mean age=37.1),who self-identified as racial minority groups(coloured/black/Indian).Results indicate that inclusive leadership has no direct effect on authenticity at work;however,psychological safety fully mediates this relationship.Regarding the moderation effect of gender,results showed that males are more likely to diminish their self-alienation(a specific component of authenticity at work)when levels of psychological safety are higher.These results are consistent with Social Identity Theory,which posits that individuals derive part of their self-concept from their membership in social groups.In contexts where inclusive leadership fosters psychological safety,individuals(particularly men in traditionally male-dominated work environments)may feel a stronger sense of belonging and group identity,which in turn enhances their willingness to express their authentic selves and reduces self-alienation.Practical implications for companies include the need to improve leadership styles to foster more of an inclusive and psychologically safe culture,where minority groups can be authentic and flourish.展开更多
This study examines the mediating role of positive psychological capital and the moderating role of ethnicity in the relationship between mindfulness and internalizing/externalizing problems among adolescents.The stud...This study examines the mediating role of positive psychological capital and the moderating role of ethnicity in the relationship between mindfulness and internalizing/externalizing problems among adolescents.The study sample comprized Chinese adolescents(N=637 ethnic minority;females=40.97%,meam age=12.68,SD=0.49 years;N=636 Han;females=49.06%,mean age=12.71,SD=0.47 years).The participants completed the Child and Adolescent Mindfulness Measure,the Positive Psycap Questionnaire,and the Youth Self-Report.Results from the moderated mediation analysis showed mindfulness was negatively associated with both internalizing and externalizing problems.Ethnicity moderated the relationship between mindfulness and internalizing problems to be stronger for Han adolescents compared to ethnic minority adolescents.Psychological capital mediated the relationship between mindfulness and internalizing problems in both groups,with a negative direction.Findings support the Conservation of Resources theory and highlight mindfulness as a personal resource fostering adolescent well-being in multicultural contexts.展开更多
China Improves Child Welfare,Strengthens Care for Minors China's Ministry of Civil Affairs has released two regulatory documents aimed at improving the approach to child welfare and assistance for minors,both of w...China Improves Child Welfare,Strengthens Care for Minors China's Ministry of Civil Affairs has released two regulatory documents aimed at improving the approach to child welfare and assistance for minors,both of which are set to take effect on April 1.Under the newly formulated interim measures,assistance and protection facilities for minors are established by governments.展开更多
Vaccination is a key strategy to curb the spread of epidemics.Heterologous vaccination,unlike homologous vaccination which acts on a single target and forms a single immune barrier,covers multiple targets for broader ...Vaccination is a key strategy to curb the spread of epidemics.Heterologous vaccination,unlike homologous vaccination which acts on a single target and forms a single immune barrier,covers multiple targets for broader protection.Yet,heterologous vaccination involves a complex decision process that conventional game-theoretic approaches,such as classical,evolutionary,and minority games cannot adequately capture.The parallel minority game(PMG)can handle bounded-rational,multi-choice decisions,but its application in vaccine research remains rare.In this study,we propose a vaccination-transmission coupled dynamic mechanism based on the parallel minority game and simulate it on a two-dimensional lattice.Using actual observational data and a mean-field mathematical model,we verify the effectiveness of this mechanism in simulating realistic vaccination behavior and transmission dynamics.We further analyze the impact of key parameters,such as vaccine efficacy differences and the proportion of individuals eligible for vaccine switching,on containment effectiveness.Our results demonstrate that heterologous vaccination surpasses homologous vaccination in containment effectiveness,particularly when vaccine efficacy varies significantly.This work provides a novel framework and empirical evidence for understanding individual decision-making and population-wide immunity formation in multi-vaccine settings.展开更多
In this paper,the property degradation micromechanism of Al-5.10Cu-0.65 Mg-0.8Mn(wt%)alloy induced by 0.5 wt%Fe minor addition was revealed by atomic-scale scanning transmission electron microscopy and energy-dispersi...In this paper,the property degradation micromechanism of Al-5.10Cu-0.65 Mg-0.8Mn(wt%)alloy induced by 0.5 wt%Fe minor addition was revealed by atomic-scale scanning transmission electron microscopy and energy-dispersive X-ray spectroscopy coupled with first-principles calculations.The results show that the Fe minor addition to the Al-Cu-Mg-Mn alloy leads to a slight reduction of grain size and the formation of coarse Al7Cu2Fe constituent particles.Fe tends to segregate into the T-phase dispersoids,θ'-,and S-phase precipitates by preferentially occupying Cu or Mn sites in these phase structures.The apparent Fe segregation contributes to an increase in stiffness of the T-phase and S-phase but decreased stiffness of theθ'phase.Formation of the coarse Al7Cu2Fe constituent particles and decreased stiffness of main precipitatesθ'containing Fe result in the degraded strength of the Al-Cu-Mg-Mn-Fe alloy.Further study reveals that corrosion resistance degradation of the Al-Cu-Mg-Mn-Fe alloy is associated with the increased width of precipitation free zones and consecutive grain boundary precipitates.The obtained results have significant implications for the usage of recycled Al alloys and the potential design strategies of high-performance alloys containing Fe.展开更多
BACKGROUND Metabolic dysfunction-associated steatohepatitis(MASH)is increasingly common,as is hepatocellular carcinoma(HCC)in the background of MASH.Liver transplantation(LT)provides superior long-term survival for pa...BACKGROUND Metabolic dysfunction-associated steatohepatitis(MASH)is increasingly common,as is hepatocellular carcinoma(HCC)in the background of MASH.Liver transplantation(LT)provides superior long-term survival for patients with unresectable MASH-HCC,but not all patients have equal access to transplant.MASH-HCC disproportionately affects Hispanic patients,but minorities are less likely to undergo LT for HCC.Additionally,females also undergo LT at lower rates than males.AIM To investigate whether race/ethnicity and sex affect LT waitlist outcomes.METHODS Records of adults with MASH-HCC in the United States Organ Procurement and Transplantation Network database listed for LT between 1/2015 and 12/2021 were analyzed.RESULTS Most of the 3810 patients waitlisted for LT for MASH-HCC were non-Hispanic(NH)white(71.2%)or Hispanic(23.4%),with only 49(1.1%)NH Black candidates.Hispanics underwent LT at lower rates than NH whites(71.6%vs 78.4%,P<0.001),but race/ethnicity did not affect waitlist mortality(P=0.06).Patients with Hispanic[hazard ratio(HR)=0.85,95%CI:0.77-0.95,P=0.002]or Asian(HR=0.79,95%CI:0.63-0.98,P=0.04)race/ethnicity were less likely to undergo LT.Women were also less likely to receive LT(male:HR=1.16,95%CI:1.04-1.29,P=0.01).Patients in regions 1 and 9 were less likely to be transplanted as well(P=0.07).CONCLUSION Hispanic patients are less likely to undergo LT for MASH-HCC,concerning given their susceptibility to MASH and HCC.There were very few NH Black candidates.Disparities were also unequal across regions,which is particularly concerning in states where at-risk populations have rising cancer incidence.Additional research is needed to identify strategies for mitigating these differences in access to LT for MASH-HCC.展开更多
Under conditions of increased pollution of water resources,the search for effective and environmentally safe methods of wastewater treatment becomes an urgent task.As noted by many researchers Lemna minor L.and Azolla...Under conditions of increased pollution of water resources,the search for effective and environmentally safe methods of wastewater treatment becomes an urgent task.As noted by many researchers Lemna minor L.and Azolla caroliniana have great potential for biological treatment of wastewater.The present study is devoted to the biological treatment of municipal wastewater of Osh city(Kyrgyzstan)using aquatic plants Lemna minor L.and Azolla caroliniana Willd.Experiments were conducted in concrete basins of treatment facilities.The area of each pool was 1 m^(2),depth 30–45 cm.The temperature of nutrient media ranged from 20 to 35℃,pH from 6.1 to 8.7,and light intensity from 284 to 360 W/m^(2)FAR.The results showed that the cultivation of Lemna minor resulted in the oxygenation of wastewater and,a significant reduction of pollutants and pathogens.At the same time,the use of Azolla caroliniana provided a significant improvement in the physicochemical characteristics of water-reduction of BOD_(5)to 4.3 mgO_(2)/L,disappearance of all forms of nitrogen,as well as improvement of transparency and elimination of unpleasant odor.Thus,both plants showed high potential as biological treatment agents.The obtained data confirm the prospect of their application for a sustainable water treatment system in the conditions of southern regions of Kyrgyzstan.展开更多
Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opp...Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opportunities.Despite the complexity and typicality of Chinese mountainous ethnic minority regions in terms of eco-cultural tourism and land use dynamics,the interplay among tourism development,land use changes,and landscape ecological risk in these specific contexts has received insufficient attention.To explore how eco-cultural tourism development in ethnic minority mountainous regions affects land use and landscape ecology,this study investigates the evolution of land use in Southeast Guizhou Province from 1980-2020,integrating GIS spatial analysis,the landscape pattern index and landscape ecological risk index analysis.Over the past four decades(1980-2020),eco-cultural tourism has driven significant land use transformations characterized by substantial expansion of building land,growth of ecological land(notably forest land and water areas),and reduction of cultivated land.Concurrently,landscape ecological risk evolved through distinct phases-showing an overall increase during 1980-2000 with expanding medium-risk zones,followed by stabilization from 2000-2020.Tourism development accelerated these land transitions while fostering multifunctional compound land uses,enhancing both land value and utilization efficiency.Crucially,eco-cultural tourism in ethnic regions demonstrates capacity to reconcile ecological conservation with economic development,providing transferable models for similar regions globally.展开更多
To the editor:The superior semicircular canal dehiscence was first described by Minor et all in 1998 as a condition in which the superior semicircular canal lacks a bony covering and has gained constantly increasing i...To the editor:The superior semicircular canal dehiscence was first described by Minor et all in 1998 as a condition in which the superior semicircular canal lacks a bony covering and has gained constantly increasing interest since its discovery.2 The symptoms are varied but specific what is known as Minor syndrome or‘third mobile window’syndrome,'as patients may experience autophony with abnormally loud sounds like footsteps,chewing,breathing,eye movement,echoing voice,distortion of environmental sounds and pulsatile tinnitus.展开更多
Minority carrier lifetimesτare a fundamental parameter in semiconductor devices,representing the average time it takes for excess minority carriers to recombine.This characteristic is crucial for understanding and op...Minority carrier lifetimesτare a fundamental parameter in semiconductor devices,representing the average time it takes for excess minority carriers to recombine.This characteristic is crucial for understanding and optimizing the performance of semiconductor materials,as it directly influences charge carrier dynamics and overall device efficiency.This work presents a development of PbS thin film deposited by thermal evaporation,at which the PbS thin film was further employed for structural,optical properties,andτ.Especially,the PbS film is probed with an in-house setup for identifying theτ.The procedure is to subject the PbS thin film with a flashlight from a light source with a middle rotating frequency.The derivedτin the in-house characterization setup agrees well with the value from the higher cost characterizing approach of photoluminescence.Therefore,the in-house setup provides additional tools for identifying theτvalues for semiconductor devices.展开更多
Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class at...Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.展开更多
1|Introduction The Federal Republic of Somalia,often perceived as linguistically homogeneous,is home to a rich tapestry of dialects and minority languages that reflect its diverse cultural heritage.While Somali is the...1|Introduction The Federal Republic of Somalia,often perceived as linguistically homogeneous,is home to a rich tapestry of dialects and minority languages that reflect its diverse cultural heritage.While Somali is the official medium of communication,it is divided into two major dialects:Maxaa Tiri(spoken by approximately 60%of the population)and Maay(spoken by approximately 20%of the population)[1].Minority languages such as Bravanese(also known as Chimwiini or Chimbalazi),Mushunguli,Benadiri Somali,and Kibajuni are spoken by smaller communities,particularly in the southern and coastal regions[1].展开更多
With the rapid development of China's economy and the government's issuance of a series of rural revitalization strategies,the design of rural landscapes has garnered increasing attention.However,some rural la...With the rapid development of China's economy and the government's issuance of a series of rural revitalization strategies,the design of rural landscapes has garnered increasing attention.However,some rural landscape designs have become more urbanized,neglecting the natural ecology,distinctive characteristics,and cultural heritage of rural areas,leading to a homogenized phenomenon.To address issues such as landscape homogenization and cultural erosion in traditional villages,this paper analyzes the current status of ethnic minority village landscapes and integrates landscape design principles to propose design strategies for rural landscapes in traditional ethnic minority villages in Hunan Province.It is intended to better achieve the construction of rural landscapes in traditional ethnic minority villages in Hunan Province.展开更多
BACKGROUND Endoscopic minor papilla intervention(EMPI)is an option for diagnosing or treating symptomatic pancreatic diseases in cases with failed pancreatic duct deep cannulation via the major papilla,pancreas divisu...BACKGROUND Endoscopic minor papilla intervention(EMPI)is an option for diagnosing or treating symptomatic pancreatic diseases in cases with failed pancreatic duct deep cannulation via the major papilla,pancreas divisum with obstruction of the minor papilla,or an abnormal patulous orifice of the minor papilla during endoscopic retrograde cholangiopancreatography(ERCP).However,the relatively low pa-tency and small opening of the minor papillae pose technical challenges.AIM To evaluate the technical success,clinical success,stone clearance,and safety pro-file of EMPI for diagnosis and treatment of symptomatic pancreatic diseases.METHODS Patients diagnosed with symptomatic pancreatic diseases and EMPI between February 1996 and February 2023 were included.The primary outcomes were the initial technical success,defined as successful deep cannulation via the minor papilla(DCMP;access of the guidewire to the upstream pancreatic duct via the minor papilla)alone,overall technical success,defined as successful DCMP alone and successful DCMP with additional needle-knife precut minor papillotomy(NKPMP),and immediate clinical success,defined as>50%improvement in abdominal pain after therapeutic EMPI.Secondary outcomes included long-term clinical success at 1,3,and 7 years,pancreatic stone clearance,and procedure-related early and late adverse events(AEs).RESULTS Overall,43 patients,32 with obstructive chronic pancreatitis,8 with pancreatic divisum,and 3 with intraductal papillary mucinous neoplasm were included.The initial and overall technical success rates were 74.4%(32/43)and 88.4%(38/43),respectively.The immediate clinical success rate was 79.1%(34/43),and the long-term clinical success rates at 1,3,and 7 years were 74.7%,55.3%,and 41.5%,respectively,among the 22 patients with a follow-up period of 57.5(7-266)months.Complete and partial success of pancreatic stone clearance was achieved in 53.9%(7/13)and 15.4%(2/13),respectively.Early AEs included post-ERCP pancreatitis(PEP,n=5)and self-limiting bleeding(n=1);surgery therapy was required for 1 case with severe PEP and conservative management for the other 4 with mild PEP.Late AEs included minor papilla stricture(n=1)after endoscopic minor papillotomy and pancreatic duct stricture(n=1)after double pancreatic stent placement;no specific treatment was implemented for these events.CONCLUSION EMPI is feasible,effective,and safe for symptomatic pancreatic diseases,in terms of the technical and clinical success,stone clearance,and incidence and severity of AEs.NKPMP appears to enhance technical success.However,potential risks of developing PEP and late AEs should be kept in mind.展开更多
BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitiv...BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitivity and specificity for identifying patients at high risk of recurrence.However,use of its results as a biomarker for guiding the treatment and predicting the prognosis of naso-pharyngeal carcinoma(NPC)has not been reported.CASE SUMMARY In this case study of a patient with stage IVb NPC,we utilized ctDNA as an independent biomarker to guide treatment.Chemotherapy was administered in the early stages of the disease,and local intensity-modulated radiation therapy was added when the patient tested positive for ctDNA,while radiation therapy was stopped and the patient was observed when the ctDNA test was negative.During the follow-up period,ctDNA signals became positive before tumor progression and became negative again at the end of treatment.We also explored the potential of ctDNA in combination with Epstein-Barr virus(EBV)DNA status to predict the prognosis of NPC patients,as well as the criteria for selecting genetic mutations and the testing cycle for ctDNA analysis.CONCLUSION The results of ctDNA-based liquid biopsy can serve as an independent biomarker,either independently or in conjunction with EBV DNA status,to guide the treatment and predict the prognosis of NPC.展开更多
The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods fro...The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.展开更多
文摘This study examined the relationship between inclusive leadership and authenticity at work in racial minority groups of South Africa,taking into account the mediating role of psychological safety and the moderator role of gender,in that relationship.The sample was composed of 94 employees predominantly working in the professional services sector from South Africa(41.5%females;mean age=37.1),who self-identified as racial minority groups(coloured/black/Indian).Results indicate that inclusive leadership has no direct effect on authenticity at work;however,psychological safety fully mediates this relationship.Regarding the moderation effect of gender,results showed that males are more likely to diminish their self-alienation(a specific component of authenticity at work)when levels of psychological safety are higher.These results are consistent with Social Identity Theory,which posits that individuals derive part of their self-concept from their membership in social groups.In contexts where inclusive leadership fosters psychological safety,individuals(particularly men in traditionally male-dominated work environments)may feel a stronger sense of belonging and group identity,which in turn enhances their willingness to express their authentic selves and reduces self-alienation.Practical implications for companies include the need to improve leadership styles to foster more of an inclusive and psychologically safe culture,where minority groups can be authentic and flourish.
基金supported by the Guizhou Provincial Science and Technology Projects[Basic Science of Guizhou-[2024]Youth 309,Guizhou Platform Talents[2021]1350-046]Zunyi Science and Technology Cooperation[HZ(2024)311]+3 种基金Funding of the Chinese Academy of Social Sciences(2024SYZH005)Peking University Longitudinal Scientific Research Technical Service Project(G-252)Guizhou Provincial Graduate Student Research Fund Project(2024YJSKYJJ339)Zunyi Medical University Graduate Research Fund Project(ZYK206).
文摘This study examines the mediating role of positive psychological capital and the moderating role of ethnicity in the relationship between mindfulness and internalizing/externalizing problems among adolescents.The study sample comprized Chinese adolescents(N=637 ethnic minority;females=40.97%,meam age=12.68,SD=0.49 years;N=636 Han;females=49.06%,mean age=12.71,SD=0.47 years).The participants completed the Child and Adolescent Mindfulness Measure,the Positive Psycap Questionnaire,and the Youth Self-Report.Results from the moderated mediation analysis showed mindfulness was negatively associated with both internalizing and externalizing problems.Ethnicity moderated the relationship between mindfulness and internalizing problems to be stronger for Han adolescents compared to ethnic minority adolescents.Psychological capital mediated the relationship between mindfulness and internalizing problems in both groups,with a negative direction.Findings support the Conservation of Resources theory and highlight mindfulness as a personal resource fostering adolescent well-being in multicultural contexts.
文摘China Improves Child Welfare,Strengthens Care for Minors China's Ministry of Civil Affairs has released two regulatory documents aimed at improving the approach to child welfare and assistance for minors,both of which are set to take effect on April 1.Under the newly formulated interim measures,assistance and protection facilities for minors are established by governments.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12571549,12571592,12471463,12022113,12101573)。
文摘Vaccination is a key strategy to curb the spread of epidemics.Heterologous vaccination,unlike homologous vaccination which acts on a single target and forms a single immune barrier,covers multiple targets for broader protection.Yet,heterologous vaccination involves a complex decision process that conventional game-theoretic approaches,such as classical,evolutionary,and minority games cannot adequately capture.The parallel minority game(PMG)can handle bounded-rational,multi-choice decisions,but its application in vaccine research remains rare.In this study,we propose a vaccination-transmission coupled dynamic mechanism based on the parallel minority game and simulate it on a two-dimensional lattice.Using actual observational data and a mean-field mathematical model,we verify the effectiveness of this mechanism in simulating realistic vaccination behavior and transmission dynamics.We further analyze the impact of key parameters,such as vaccine efficacy differences and the proportion of individuals eligible for vaccine switching,on containment effectiveness.Our results demonstrate that heterologous vaccination surpasses homologous vaccination in containment effectiveness,particularly when vaccine efficacy varies significantly.This work provides a novel framework and empirical evidence for understanding individual decision-making and population-wide immunity formation in multi-vaccine settings.
基金supported by the National Natural Science Foundation of China(Nos.U20A20274 and 52061003)the Natural Science Foundation of Yunnan Province(No.202301AT070209)the Science and Technology Major Project of Yunnan Province(No.202102AG050017).
文摘In this paper,the property degradation micromechanism of Al-5.10Cu-0.65 Mg-0.8Mn(wt%)alloy induced by 0.5 wt%Fe minor addition was revealed by atomic-scale scanning transmission electron microscopy and energy-dispersive X-ray spectroscopy coupled with first-principles calculations.The results show that the Fe minor addition to the Al-Cu-Mg-Mn alloy leads to a slight reduction of grain size and the formation of coarse Al7Cu2Fe constituent particles.Fe tends to segregate into the T-phase dispersoids,θ'-,and S-phase precipitates by preferentially occupying Cu or Mn sites in these phase structures.The apparent Fe segregation contributes to an increase in stiffness of the T-phase and S-phase but decreased stiffness of theθ'phase.Formation of the coarse Al7Cu2Fe constituent particles and decreased stiffness of main precipitatesθ'containing Fe result in the degraded strength of the Al-Cu-Mg-Mn-Fe alloy.Further study reveals that corrosion resistance degradation of the Al-Cu-Mg-Mn-Fe alloy is associated with the increased width of precipitation free zones and consecutive grain boundary precipitates.The obtained results have significant implications for the usage of recycled Al alloys and the potential design strategies of high-performance alloys containing Fe.
文摘BACKGROUND Metabolic dysfunction-associated steatohepatitis(MASH)is increasingly common,as is hepatocellular carcinoma(HCC)in the background of MASH.Liver transplantation(LT)provides superior long-term survival for patients with unresectable MASH-HCC,but not all patients have equal access to transplant.MASH-HCC disproportionately affects Hispanic patients,but minorities are less likely to undergo LT for HCC.Additionally,females also undergo LT at lower rates than males.AIM To investigate whether race/ethnicity and sex affect LT waitlist outcomes.METHODS Records of adults with MASH-HCC in the United States Organ Procurement and Transplantation Network database listed for LT between 1/2015 and 12/2021 were analyzed.RESULTS Most of the 3810 patients waitlisted for LT for MASH-HCC were non-Hispanic(NH)white(71.2%)or Hispanic(23.4%),with only 49(1.1%)NH Black candidates.Hispanics underwent LT at lower rates than NH whites(71.6%vs 78.4%,P<0.001),but race/ethnicity did not affect waitlist mortality(P=0.06).Patients with Hispanic[hazard ratio(HR)=0.85,95%CI:0.77-0.95,P=0.002]or Asian(HR=0.79,95%CI:0.63-0.98,P=0.04)race/ethnicity were less likely to undergo LT.Women were also less likely to receive LT(male:HR=1.16,95%CI:1.04-1.29,P=0.01).Patients in regions 1 and 9 were less likely to be transplanted as well(P=0.07).CONCLUSION Hispanic patients are less likely to undergo LT for MASH-HCC,concerning given their susceptibility to MASH and HCC.There were very few NH Black candidates.Disparities were also unequal across regions,which is particularly concerning in states where at-risk populations have rising cancer incidence.Additional research is needed to identify strategies for mitigating these differences in access to LT for MASH-HCC.
文摘Under conditions of increased pollution of water resources,the search for effective and environmentally safe methods of wastewater treatment becomes an urgent task.As noted by many researchers Lemna minor L.and Azolla caroliniana have great potential for biological treatment of wastewater.The present study is devoted to the biological treatment of municipal wastewater of Osh city(Kyrgyzstan)using aquatic plants Lemna minor L.and Azolla caroliniana Willd.Experiments were conducted in concrete basins of treatment facilities.The area of each pool was 1 m^(2),depth 30–45 cm.The temperature of nutrient media ranged from 20 to 35℃,pH from 6.1 to 8.7,and light intensity from 284 to 360 W/m^(2)FAR.The results showed that the cultivation of Lemna minor resulted in the oxygenation of wastewater and,a significant reduction of pollutants and pathogens.At the same time,the use of Azolla caroliniana provided a significant improvement in the physicochemical characteristics of water-reduction of BOD_(5)to 4.3 mgO_(2)/L,disappearance of all forms of nitrogen,as well as improvement of transparency and elimination of unpleasant odor.Thus,both plants showed high potential as biological treatment agents.The obtained data confirm the prospect of their application for a sustainable water treatment system in the conditions of southern regions of Kyrgyzstan.
基金supported by the National Social Science Foundation of China(Grant No.20CMZ033)Fundamental Research Funds for the Central Universities(CCNU24ZZ125).
文摘Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opportunities.Despite the complexity and typicality of Chinese mountainous ethnic minority regions in terms of eco-cultural tourism and land use dynamics,the interplay among tourism development,land use changes,and landscape ecological risk in these specific contexts has received insufficient attention.To explore how eco-cultural tourism development in ethnic minority mountainous regions affects land use and landscape ecology,this study investigates the evolution of land use in Southeast Guizhou Province from 1980-2020,integrating GIS spatial analysis,the landscape pattern index and landscape ecological risk index analysis.Over the past four decades(1980-2020),eco-cultural tourism has driven significant land use transformations characterized by substantial expansion of building land,growth of ecological land(notably forest land and water areas),and reduction of cultivated land.Concurrently,landscape ecological risk evolved through distinct phases-showing an overall increase during 1980-2000 with expanding medium-risk zones,followed by stabilization from 2000-2020.Tourism development accelerated these land transitions while fostering multifunctional compound land uses,enhancing both land value and utilization efficiency.Crucially,eco-cultural tourism in ethnic regions demonstrates capacity to reconcile ecological conservation with economic development,providing transferable models for similar regions globally.
文摘To the editor:The superior semicircular canal dehiscence was first described by Minor et all in 1998 as a condition in which the superior semicircular canal lacks a bony covering and has gained constantly increasing interest since its discovery.2 The symptoms are varied but specific what is known as Minor syndrome or‘third mobile window’syndrome,'as patients may experience autophony with abnormally loud sounds like footsteps,chewing,breathing,eye movement,echoing voice,distortion of environmental sounds and pulsatile tinnitus.
基金funded by The Vietnam Ministry of Education and Training under project number B2024-BKA-12.
文摘Minority carrier lifetimesτare a fundamental parameter in semiconductor devices,representing the average time it takes for excess minority carriers to recombine.This characteristic is crucial for understanding and optimizing the performance of semiconductor materials,as it directly influences charge carrier dynamics and overall device efficiency.This work presents a development of PbS thin film deposited by thermal evaporation,at which the PbS thin film was further employed for structural,optical properties,andτ.Especially,the PbS film is probed with an in-house setup for identifying theτ.The procedure is to subject the PbS thin film with a flashlight from a light source with a middle rotating frequency.The derivedτin the in-house characterization setup agrees well with the value from the higher cost characterizing approach of photoluminescence.Therefore,the in-house setup provides additional tools for identifying theτvalues for semiconductor devices.
基金supported by the Institute of Information&Communications Technology Planning&Evaluation(IITP)—Innovative Human Resource Development for Local Intellectualization program grant funded by the Korea government(MSIT)(IITP-2025-RS-2022-00156334)in part by Liaoning Province Nature Fund Project(2024-BSLH-214).
文摘Network Intrusion Detection System(NIDS)detection of minority class attacks is always a difficult task when dealing with attacks in complex network environments.To improve the detection capability of minority-class attacks,this study proposes an intrusion detection method based on a two-layer structure.The first layer employs a CNN-BiLSTM model incorporating an attention mechanism to classify network traffic into normal traffic,majority class attacks,and merged minority class attacks.The second layer further segments the minority class attacks through Stacking ensemble learning.The datasets are selected from the generic network dataset CIC-IDS2017,NSL-KDD,and the industrial network dataset Mississippi Gas Pipeline dataset to enhance the generalization and practical applicability of the model.Experimental results show that the proposed model achieves an overall detection accuracy of 99%,99%,and 95%on the CIC-IDS2017,NSL-KDD,and industrial network datasets,respectively.It also significantly outperforms traditional methods in terms of detection accuracy and recall rate for minority class attacks.Compared with the single-layer deep learning model,the two-layer structure effectively reduces the false alarm rate while improving the minority-class attack detection performance.The research in this paper not only improves the adaptability of NIDS to complex network environments but also provides a new solution for minority-class attack detection in industrial network security.
文摘1|Introduction The Federal Republic of Somalia,often perceived as linguistically homogeneous,is home to a rich tapestry of dialects and minority languages that reflect its diverse cultural heritage.While Somali is the official medium of communication,it is divided into two major dialects:Maxaa Tiri(spoken by approximately 60%of the population)and Maay(spoken by approximately 20%of the population)[1].Minority languages such as Bravanese(also known as Chimwiini or Chimbalazi),Mushunguli,Benadiri Somali,and Kibajuni are spoken by smaller communities,particularly in the southern and coastal regions[1].
基金Supported by Key Scientific Research Project of the Department of Education of Hunan Province in 2022"Research on Art and Design Strategies for Rural Revitalization in Ethnic Minority Traditional Villages of Hunan under the New Development Concept"(22A0396).
文摘With the rapid development of China's economy and the government's issuance of a series of rural revitalization strategies,the design of rural landscapes has garnered increasing attention.However,some rural landscape designs have become more urbanized,neglecting the natural ecology,distinctive characteristics,and cultural heritage of rural areas,leading to a homogenized phenomenon.To address issues such as landscape homogenization and cultural erosion in traditional villages,this paper analyzes the current status of ethnic minority village landscapes and integrates landscape design principles to propose design strategies for rural landscapes in traditional ethnic minority villages in Hunan Province.It is intended to better achieve the construction of rural landscapes in traditional ethnic minority villages in Hunan Province.
基金Supported by Heilongjiang Provincial Natural Science Foundation Team Project,No.TD2020H002.
文摘BACKGROUND Endoscopic minor papilla intervention(EMPI)is an option for diagnosing or treating symptomatic pancreatic diseases in cases with failed pancreatic duct deep cannulation via the major papilla,pancreas divisum with obstruction of the minor papilla,or an abnormal patulous orifice of the minor papilla during endoscopic retrograde cholangiopancreatography(ERCP).However,the relatively low pa-tency and small opening of the minor papillae pose technical challenges.AIM To evaluate the technical success,clinical success,stone clearance,and safety pro-file of EMPI for diagnosis and treatment of symptomatic pancreatic diseases.METHODS Patients diagnosed with symptomatic pancreatic diseases and EMPI between February 1996 and February 2023 were included.The primary outcomes were the initial technical success,defined as successful deep cannulation via the minor papilla(DCMP;access of the guidewire to the upstream pancreatic duct via the minor papilla)alone,overall technical success,defined as successful DCMP alone and successful DCMP with additional needle-knife precut minor papillotomy(NKPMP),and immediate clinical success,defined as>50%improvement in abdominal pain after therapeutic EMPI.Secondary outcomes included long-term clinical success at 1,3,and 7 years,pancreatic stone clearance,and procedure-related early and late adverse events(AEs).RESULTS Overall,43 patients,32 with obstructive chronic pancreatitis,8 with pancreatic divisum,and 3 with intraductal papillary mucinous neoplasm were included.The initial and overall technical success rates were 74.4%(32/43)and 88.4%(38/43),respectively.The immediate clinical success rate was 79.1%(34/43),and the long-term clinical success rates at 1,3,and 7 years were 74.7%,55.3%,and 41.5%,respectively,among the 22 patients with a follow-up period of 57.5(7-266)months.Complete and partial success of pancreatic stone clearance was achieved in 53.9%(7/13)and 15.4%(2/13),respectively.Early AEs included post-ERCP pancreatitis(PEP,n=5)and self-limiting bleeding(n=1);surgery therapy was required for 1 case with severe PEP and conservative management for the other 4 with mild PEP.Late AEs included minor papilla stricture(n=1)after endoscopic minor papillotomy and pancreatic duct stricture(n=1)after double pancreatic stent placement;no specific treatment was implemented for these events.CONCLUSION EMPI is feasible,effective,and safe for symptomatic pancreatic diseases,in terms of the technical and clinical success,stone clearance,and incidence and severity of AEs.NKPMP appears to enhance technical success.However,potential risks of developing PEP and late AEs should be kept in mind.
基金Supported by Beijing Bethune Charitable Foundation and Provincial Natural Science Foundation of Liaoning,No.2022-MS-190.
文摘BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitivity and specificity for identifying patients at high risk of recurrence.However,use of its results as a biomarker for guiding the treatment and predicting the prognosis of naso-pharyngeal carcinoma(NPC)has not been reported.CASE SUMMARY In this case study of a patient with stage IVb NPC,we utilized ctDNA as an independent biomarker to guide treatment.Chemotherapy was administered in the early stages of the disease,and local intensity-modulated radiation therapy was added when the patient tested positive for ctDNA,while radiation therapy was stopped and the patient was observed when the ctDNA test was negative.During the follow-up period,ctDNA signals became positive before tumor progression and became negative again at the end of treatment.We also explored the potential of ctDNA in combination with Epstein-Barr virus(EBV)DNA status to predict the prognosis of NPC patients,as well as the criteria for selecting genetic mutations and the testing cycle for ctDNA analysis.CONCLUSION The results of ctDNA-based liquid biopsy can serve as an independent biomarker,either independently or in conjunction with EBV DNA status,to guide the treatment and predict the prognosis of NPC.
基金supports from the National Natural Science Foundation of China(NSFC,grant Nos.12203002 and 11973015)supports from the National Key Basic R&D Program of China via 2023YFA1608303 and the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0550103)+6 种基金supports from the National Natural Science Foundation of China(NSFCgrant No.12373015)supports from the National Natural Science Foundation of China(NSFCgrant Nos.12120101003 and 12373010)National Key R&D Program of China(grant Nos.2023YFA1607800,2023YFA1607804,2022YFA1602902)Beijing Municipal Natural Science Foundation(grant No.1222028)Strategic Priority Research Program of the Chinese Academy of Science(grant Nos.XDB0550100 and XDB0550000).
文摘The SiTian project,with its vast field of view,will become an ideal platform for scientific research on asteroids.In this study,we develop a pipeline to analyze the photometry of asteroids and derive their periods from the data collected by the SiTian pathfinder project Mini-SiTian(MST).The pipeline is applied to the MST f02 region,an MST test region with a sky area of 2°.29×1°.53.Rotation periods of 22 asteroids are derived by the obtained light curve analysis.Among them,there are eight asteroids available in the Asteroid Lightcurve Photometry Database(ALCDEF),and six of them with more photometric points(>200)that have similar period parameters as the ones in ALCDEF.Additionally,the periods for 14 of these asteroids are newly obtained and are not listed in ALCDEF.This study demonstrates the feasibility of asteroid photometric research by the SiTian project.It shows that future observations from the SiTian project will provide even more photometry of asteroids,significantly increasing the number of available light curves.The potential vast photometric data on asteroids will help us to further understand the physics of asteroids,their material composition,and the formation and evolution of the solar system.
