The generation of heliothermal electricity has received increasing attention throughout the world in countries such as Spain, the USA, Germany and many others. In Brazil, this type of energy generation in the form of ...The generation of heliothermal electricity has received increasing attention throughout the world in countries such as Spain, the USA, Germany and many others. In Brazil, this type of energy generation in the form of large projects (above 80 MW) remains unexplored. However, it is known that in the country, there are extensive areas of normal direct irradiation with high intensity and a low seasonality factor, especially in the semiarid regions in Brazil, mainly the North and Northeast of Minas Gerais. Moreover, these Minas Gerais regions have other significant characteristics for the installation of these plants: proximity to transmission lines, flatness, the fact that the respective vegetation is not endangered, a suitable land use profile (availability of land not used in agriculture), low wind speed, low population density, and, most recently, an increase in the demand for local electric energy due to the economic growth above the Brazilian average rate. Furthermore, the introduction of solar plants in that region, due to its distributed nature, will bring development and growth to the region (normally poor) by generating employment and income. This article presents a study of the optimal location of thermoelectric plants in the semiarid regions of Minas Gerais, conducted with Geographical Information System (GIS) technology. GIS consists of a set of specialised resources that allow the manipulation of spatial data, bringing efficiency and agility in the identification of suitable places for the installation of solar plants, while simultaneously enabling the consideration of future scenarios for energy planning, with its respective impact, costs and benefits. The study has identified very promising solar irradiation levels for the electric generation by solar energy, whether thermoelectric or photovoltaic, reaching an annual solar irradiation of 2700 kWh/m2 in the summer and in the range of 2200 - 2400 kWh/m2 on an annual basis. This area includes a vast region in the North/Northeast of the state, which also has continuous and flat regions, with slopes inferior to 3%;in addition, high-quality hydro resources are abundant and well distributed. Furthermore, the Minas Gerais region has few areas with high agriculture profile and reduced quantity of protected units. Therefore, generally speaking, the coverage of the transmission lines in that region is suitable. Considering the most relevant aspects mentioned before, and taking as a reference the micro-region limits defined by the IBGE, the following micro-regions were classified as the most promising ones: 1) Janaúba, 2) Januária, 3) Pirapora and Unaí, 4) Pirapora and Paracatu, 5) Curvelo and Três Marias, and 6) Patrocínio and Araxá. Finally, it is important to highlight that this potential might be explored gradually in the medium term, with the shortage of other supply sources, the scale up and readiness of such technologies, as well as the creation of a complex solar-wind-hydro system that leverages the strong complementarity of such resources, as has been observed.展开更多
Objective:To identify an unusual encrusting calcareous organism found growing on upper intertidal rocks along the coast of the Minas Basin,Nova Scotia,Canada,which was thought to potentially represent a new,perhaps in...Objective:To identify an unusual encrusting calcareous organism found growing on upper intertidal rocks along the coast of the Minas Basin,Nova Scotia,Canada,which was thought to potentially represent a new,perhaps invasive species to the area.Methods:Observations were made of the organism growing in situ and of intact and dissected specimens under microscopes in the laboratory.Taxonomic keys were used to determine probable identity of the organism as a tunicate,sponge,bryozoan,marine lichen,or coralline red alga.These keys were then further used to identify samples to species.Results:The organism was determined to be Phymatolithon lamii(Me.Lemoine)Y.M.Chamberlain 1991,an encrusting coralline red alga native to the study region.This species normally occurs in the subtidal zone,so its occurrence in the high intertidal zone was unusual and resulted in the alga becoming bleached and taking on an unusual appearance.Conclusions:The sample did not represent a new or invasive species to the study area.However,occurrence of this species on the high intertidal zone was novel and may have resulted from unusual climatic and/or oceanographic conditions in the study area in 2015 that allowed this alga to settle and grow in the intertidal zone for a time before death and bleaching occurred.Events such as this resulting from climate change may negatively impact recruitment to populations of coastal marine species and should be investigated further.展开更多
c-Myc的下游靶基因Myc-induced nuclear antigen with a molecular mass of 53 k Da(Mina53)在多种肿瘤组织中异常表达,且与肿瘤临床分期、淋巴结转移及临床预后之间关系密切。Mina53可通过调控细胞分化、增殖、凋亡等参与肿瘤发生发展...c-Myc的下游靶基因Myc-induced nuclear antigen with a molecular mass of 53 k Da(Mina53)在多种肿瘤组织中异常表达,且与肿瘤临床分期、淋巴结转移及临床预后之间关系密切。Mina53可通过调控细胞分化、增殖、凋亡等参与肿瘤发生发展,但其相关作用机制还不十分清楚。为此,本文拟通过综述Mina53在肿瘤发生发展中的机制研究进展,探讨其在肿瘤治疗中的意义和价值。展开更多
目的:探讨Bmi-1(B-cell-specific moloney murine leukemia virus insertion site 1)和Mina53(myc-induced nuclear antigen with a molecular mass of 53 k Da)在大肠癌(colorectal carcinoma,CRC)组织中的表达及临床病理意义.方法:采...目的:探讨Bmi-1(B-cell-specific moloney murine leukemia virus insertion site 1)和Mina53(myc-induced nuclear antigen with a molecular mass of 53 k Da)在大肠癌(colorectal carcinoma,CRC)组织中的表达及临床病理意义.方法:采用免疫组织化学法分别检测56例CRC及相应癌旁正常大肠黏膜组织中Bmi-1和Mina53蛋白的表达,并分析两者的表达水平相关性及与临床病理因素的关系.结果:CRC及相应癌旁正常大肠黏膜组织中Bmi-1蛋白的阳性表达率分别为80.4%和35.7%,M i n a53蛋白的阳性表达率分别为73.2%和19.6%,组间相比差异均有统计学意义(χ2=22.913、32.308,均P<0.05).CRC组织中Bmi-1和Mina53蛋白的表达与患者的性别、年龄无关(均P>0.05),而与肿瘤的分化程度、淋巴转移及浸润深度有关(均P<0.05).CRC组织中Bmi-1和Mina53蛋白的表达呈正关联(r=0.296,P<0.05).结论:Bmi-1和Mina53的高表达可能与CRC的发生、发展及预后有关,联合检测两者对CRC的诊断及预后判断可能具有重要意义.展开更多
文摘The generation of heliothermal electricity has received increasing attention throughout the world in countries such as Spain, the USA, Germany and many others. In Brazil, this type of energy generation in the form of large projects (above 80 MW) remains unexplored. However, it is known that in the country, there are extensive areas of normal direct irradiation with high intensity and a low seasonality factor, especially in the semiarid regions in Brazil, mainly the North and Northeast of Minas Gerais. Moreover, these Minas Gerais regions have other significant characteristics for the installation of these plants: proximity to transmission lines, flatness, the fact that the respective vegetation is not endangered, a suitable land use profile (availability of land not used in agriculture), low wind speed, low population density, and, most recently, an increase in the demand for local electric energy due to the economic growth above the Brazilian average rate. Furthermore, the introduction of solar plants in that region, due to its distributed nature, will bring development and growth to the region (normally poor) by generating employment and income. This article presents a study of the optimal location of thermoelectric plants in the semiarid regions of Minas Gerais, conducted with Geographical Information System (GIS) technology. GIS consists of a set of specialised resources that allow the manipulation of spatial data, bringing efficiency and agility in the identification of suitable places for the installation of solar plants, while simultaneously enabling the consideration of future scenarios for energy planning, with its respective impact, costs and benefits. The study has identified very promising solar irradiation levels for the electric generation by solar energy, whether thermoelectric or photovoltaic, reaching an annual solar irradiation of 2700 kWh/m2 in the summer and in the range of 2200 - 2400 kWh/m2 on an annual basis. This area includes a vast region in the North/Northeast of the state, which also has continuous and flat regions, with slopes inferior to 3%;in addition, high-quality hydro resources are abundant and well distributed. Furthermore, the Minas Gerais region has few areas with high agriculture profile and reduced quantity of protected units. Therefore, generally speaking, the coverage of the transmission lines in that region is suitable. Considering the most relevant aspects mentioned before, and taking as a reference the micro-region limits defined by the IBGE, the following micro-regions were classified as the most promising ones: 1) Janaúba, 2) Januária, 3) Pirapora and Unaí, 4) Pirapora and Paracatu, 5) Curvelo and Três Marias, and 6) Patrocínio and Araxá. Finally, it is important to highlight that this potential might be explored gradually in the medium term, with the shortage of other supply sources, the scale up and readiness of such technologies, as well as the creation of a complex solar-wind-hydro system that leverages the strong complementarity of such resources, as has been observed.
文摘Objective:To identify an unusual encrusting calcareous organism found growing on upper intertidal rocks along the coast of the Minas Basin,Nova Scotia,Canada,which was thought to potentially represent a new,perhaps invasive species to the area.Methods:Observations were made of the organism growing in situ and of intact and dissected specimens under microscopes in the laboratory.Taxonomic keys were used to determine probable identity of the organism as a tunicate,sponge,bryozoan,marine lichen,or coralline red alga.These keys were then further used to identify samples to species.Results:The organism was determined to be Phymatolithon lamii(Me.Lemoine)Y.M.Chamberlain 1991,an encrusting coralline red alga native to the study region.This species normally occurs in the subtidal zone,so its occurrence in the high intertidal zone was unusual and resulted in the alga becoming bleached and taking on an unusual appearance.Conclusions:The sample did not represent a new or invasive species to the study area.However,occurrence of this species on the high intertidal zone was novel and may have resulted from unusual climatic and/or oceanographic conditions in the study area in 2015 that allowed this alga to settle and grow in the intertidal zone for a time before death and bleaching occurred.Events such as this resulting from climate change may negatively impact recruitment to populations of coastal marine species and should be investigated further.
文摘c-Myc的下游靶基因Myc-induced nuclear antigen with a molecular mass of 53 k Da(Mina53)在多种肿瘤组织中异常表达,且与肿瘤临床分期、淋巴结转移及临床预后之间关系密切。Mina53可通过调控细胞分化、增殖、凋亡等参与肿瘤发生发展,但其相关作用机制还不十分清楚。为此,本文拟通过综述Mina53在肿瘤发生发展中的机制研究进展,探讨其在肿瘤治疗中的意义和价值。
文摘目的:探讨Bmi-1(B-cell-specific moloney murine leukemia virus insertion site 1)和Mina53(myc-induced nuclear antigen with a molecular mass of 53 k Da)在大肠癌(colorectal carcinoma,CRC)组织中的表达及临床病理意义.方法:采用免疫组织化学法分别检测56例CRC及相应癌旁正常大肠黏膜组织中Bmi-1和Mina53蛋白的表达,并分析两者的表达水平相关性及与临床病理因素的关系.结果:CRC及相应癌旁正常大肠黏膜组织中Bmi-1蛋白的阳性表达率分别为80.4%和35.7%,M i n a53蛋白的阳性表达率分别为73.2%和19.6%,组间相比差异均有统计学意义(χ2=22.913、32.308,均P<0.05).CRC组织中Bmi-1和Mina53蛋白的表达与患者的性别、年龄无关(均P>0.05),而与肿瘤的分化程度、淋巴转移及浸润深度有关(均P<0.05).CRC组织中Bmi-1和Mina53蛋白的表达呈正关联(r=0.296,P<0.05).结论:Bmi-1和Mina53的高表达可能与CRC的发生、发展及预后有关,联合检测两者对CRC的诊断及预后判断可能具有重要意义.
