Microvenular hemangioma(MVH)is a rare,benign type of hemangioma that typically presents as a solitary,slow-growing,red-to-violaceous asymptomatic papule,plaque,or nodule.It most commonly locations of the lesions on th...Microvenular hemangioma(MVH)is a rare,benign type of hemangioma that typically presents as a solitary,slow-growing,red-to-violaceous asymptomatic papule,plaque,or nodule.It most commonly locations of the lesions on the limbs and trunk,with no prior reports of MVH confined to the breast.We present the first reported case of multiple MVH confined to the breast in a 17-year-old female patient.The case is notable for its unique and atypical clinical features.Diagnosing MVH is challenging and requires routine pathological and im-munohistochemical staining.Histological testing revealed typical features of MVH,irregularly branched small or medium vascular interstitial spaces lined with benign endothelial cells and positivity for CD34 and CD31.This case emphasizes the need to consider MVH in the dif-ferential diagnosis of breast vascular lesions,particularly in young patients.It also underscores the importance of histological and immu-nohistochemical analyses for an accurate diagnosis.展开更多
基金supported by grants from the National Natural Science Foundation of China(no.82104952,no.82004240)Special Project for Clinical Research of Health Industry of Shanghai Municipal Health Commission(no.202140172)+2 种基金Special Project of Medical Innovation Research of Shanghai Science and Technology Commission(no.21Y11923600,no.23Y11921600)Yueyang Hospital of Integrated Traditional Chinese and Western Medicine of Translational Medicine Research Fund(no.2024YYZH05)Young Talents Training Project of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine(no.RY411.07.02.04).
文摘Microvenular hemangioma(MVH)is a rare,benign type of hemangioma that typically presents as a solitary,slow-growing,red-to-violaceous asymptomatic papule,plaque,or nodule.It most commonly locations of the lesions on the limbs and trunk,with no prior reports of MVH confined to the breast.We present the first reported case of multiple MVH confined to the breast in a 17-year-old female patient.The case is notable for its unique and atypical clinical features.Diagnosing MVH is challenging and requires routine pathological and im-munohistochemical staining.Histological testing revealed typical features of MVH,irregularly branched small or medium vascular interstitial spaces lined with benign endothelial cells and positivity for CD34 and CD31.This case emphasizes the need to consider MVH in the dif-ferential diagnosis of breast vascular lesions,particularly in young patients.It also underscores the importance of histological and immu-nohistochemical analyses for an accurate diagnosis.
