Objective: to analyze the difference of efficacy and safety between intravascular interventional therapy and microneurosurgery in the treatment of intracranial artery tumor (ICA), and to provide reference for the rati...Objective: to analyze the difference of efficacy and safety between intravascular interventional therapy and microneurosurgery in the treatment of intracranial artery tumor (ICA), and to provide reference for the rationality of surgical plan. Methods: a total of 96 ICA patients were selected from our hospital according to the purpose, procedure and requirements of the study. Forty-eight ICA patients were selected by the method of drawing lots. Forty-eight ICA patients were selected as the control group after intravascular interventional therapy, and forty-eight ICA patients were selected as the extra-nervous group after microneurosurgery. Results: the good recovery rate and mild disability rate of patients in shenshen group were significantly higher than those in control group (P <0.05), and the complication rate was significantly lower than that in control group (P <0.05). Conclusion: microneurosurgery can significantly improve the postoperative physical recovery of ICA patients and have a good effect on prevention of complications.展开更多
INTRODUCTIONMicroneurosurgery made its debut in the early 1960s. It became popular in the medical field and became a primary operation method in neurosurgery since it improved the efficacy of neurosurgery with a less ...INTRODUCTIONMicroneurosurgery made its debut in the early 1960s. It became popular in the medical field and became a primary operation method in neurosurgery since it improved the efficacy of neurosurgery with a less surgery-related injury. Over the past five decades, the accumulation of experience of microsurgery, improvement of microsurgery techniques, refined micro-instruments, and advanced preoperative diagnostic imaging allowed the evolution of microneurosurgery techniques and further reduced surgery-related trauma.展开更多
The skull base communicating tumor is characterized by simultaneous invasion of the intracranial and extracranial structures. The tumor may originate from the intracranial structures and invade extracranially, or vice...The skull base communicating tumor is characterized by simultaneous invasion of the intracranial and extracranial structures. The tumor may originate from the intracranial structures and invade extracranially, or vice versa. The total resection of the tumor is difficult, and a lot of complications may occur after the operation.1 From September 1998 to September 2002, 21 patients with skull base communicating tumors were treated in our hospital by endoscope-assisted combined with diode laser through approaches. microneurosurgery different operative展开更多
Translational medicine, normally refers to a process for transitioning from the initial lab discovery to the patient＇s bedside with minimal disconnect comprehensive review of statistical and offers a design and metho...Translational medicine, normally refers to a process for transitioning from the initial lab discovery to the patient＇s bedside with minimal disconnect comprehensive review of statistical and offers a design and methodology. It has been advocated repeatedly by worldwide medical scientists as the new prospect highlighting the transition for scientific achievements from laboratory results to clinical application in recent years. As for neurosurgery, it is generally acknowledged that it has been improving in basic research and clinical practice by bounds and leaps; however, the achievements in basic and clinical neurosurgical studies seem to be parallel with no intersection for mutual interaction. Minimally invasive neurosurgery is aimed at serving as the intersection platform for translational medicine.展开更多
Background:Petroclival meningiomas(PCMs)are technically challenging lesions.Although the standard retrosigmoid approach is one of the most effective approaches,this route may have some limitations for the tumors exten...Background:Petroclival meningiomas(PCMs)are technically challenging lesions.Although the standard retrosigmoid approach is one of the most effective approaches,this route may have some limitations for the tumors extending into the supratentorial region and middle cranial fossa.We provide a modified surgical technique called retrosigmoid-transtentorial approach(RTTA)to solve these problems.The feasibility and efficacy of the RTTA were studied,by analyzing neurological outcomes and considerations of surgical strategies.Methods:We analyzed 64 of 71 PCM patients(90.1%).All 64 patients had epicenter of tumor in the posterior fossa with varying degrees of extension into the supratentorial area and/or the middle fossa.A conventional retrosigmoid craniotomy was performed following which the tentorium was incised from the attachment of tumor toward the free edge,which improved exposure to the petroclival region by offering additional operative room without resection of the adjacent part of the petrous bone.Results:The rate of gross total resection was 71.9%.There was no incidence of intraoperative death.One patient died in the postoperative phase.The postoperative permanent morbidity rate was 25.4%.Follow-up was done with the mean time of 60.7±47.5 months.There were 6 recurrence,8 progression and 7 death cases and the mean KPS score was 83.2±13.4 in the last follow up.Conclusions:The RTTA achieves the goal of applying a safe,quick,uncomplicated,and lesser invasive access to the petroclival region which is indicated for tumors located in the posterior fossa with some extension into the supratentorial area and/or the middle fossa.展开更多
文摘Objective: to analyze the difference of efficacy and safety between intravascular interventional therapy and microneurosurgery in the treatment of intracranial artery tumor (ICA), and to provide reference for the rationality of surgical plan. Methods: a total of 96 ICA patients were selected from our hospital according to the purpose, procedure and requirements of the study. Forty-eight ICA patients were selected by the method of drawing lots. Forty-eight ICA patients were selected as the control group after intravascular interventional therapy, and forty-eight ICA patients were selected as the extra-nervous group after microneurosurgery. Results: the good recovery rate and mild disability rate of patients in shenshen group were significantly higher than those in control group (P <0.05), and the complication rate was significantly lower than that in control group (P <0.05). Conclusion: microneurosurgery can significantly improve the postoperative physical recovery of ICA patients and have a good effect on prevention of complications.
文摘INTRODUCTIONMicroneurosurgery made its debut in the early 1960s. It became popular in the medical field and became a primary operation method in neurosurgery since it improved the efficacy of neurosurgery with a less surgery-related injury. Over the past five decades, the accumulation of experience of microsurgery, improvement of microsurgery techniques, refined micro-instruments, and advanced preoperative diagnostic imaging allowed the evolution of microneurosurgery techniques and further reduced surgery-related trauma.
基金Zhejiang Province Intensive Generalized Project for Medicine Scientific and Technological Production (No. 2005TG012)
文摘The skull base communicating tumor is characterized by simultaneous invasion of the intracranial and extracranial structures. The tumor may originate from the intracranial structures and invade extracranially, or vice versa. The total resection of the tumor is difficult, and a lot of complications may occur after the operation.1 From September 1998 to September 2002, 21 patients with skull base communicating tumors were treated in our hospital by endoscope-assisted combined with diode laser through approaches. microneurosurgery different operative
文摘Translational medicine, normally refers to a process for transitioning from the initial lab discovery to the patient＇s bedside with minimal disconnect comprehensive review of statistical and offers a design and methodology. It has been advocated repeatedly by worldwide medical scientists as the new prospect highlighting the transition for scientific achievements from laboratory results to clinical application in recent years. As for neurosurgery, it is generally acknowledged that it has been improving in basic research and clinical practice by bounds and leaps; however, the achievements in basic and clinical neurosurgical studies seem to be parallel with no intersection for mutual interaction. Minimally invasive neurosurgery is aimed at serving as the intersection platform for translational medicine.
基金supported by grants from the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (No.2014BAI04B02).
文摘Background:Petroclival meningiomas(PCMs)are technically challenging lesions.Although the standard retrosigmoid approach is one of the most effective approaches,this route may have some limitations for the tumors extending into the supratentorial region and middle cranial fossa.We provide a modified surgical technique called retrosigmoid-transtentorial approach(RTTA)to solve these problems.The feasibility and efficacy of the RTTA were studied,by analyzing neurological outcomes and considerations of surgical strategies.Methods:We analyzed 64 of 71 PCM patients(90.1%).All 64 patients had epicenter of tumor in the posterior fossa with varying degrees of extension into the supratentorial area and/or the middle fossa.A conventional retrosigmoid craniotomy was performed following which the tentorium was incised from the attachment of tumor toward the free edge,which improved exposure to the petroclival region by offering additional operative room without resection of the adjacent part of the petrous bone.Results:The rate of gross total resection was 71.9%.There was no incidence of intraoperative death.One patient died in the postoperative phase.The postoperative permanent morbidity rate was 25.4%.Follow-up was done with the mean time of 60.7±47.5 months.There were 6 recurrence,8 progression and 7 death cases and the mean KPS score was 83.2±13.4 in the last follow up.Conclusions:The RTTA achieves the goal of applying a safe,quick,uncomplicated,and lesser invasive access to the petroclival region which is indicated for tumors located in the posterior fossa with some extension into the supratentorial area and/or the middle fossa.
