Saad et al.'s review~([1]),“Emerging trends in the management of non-obstructive azoospermia,”offers a compelling synthesis of cutting-edge diagnostic and therapeutic strategies for non-obstructive azoospermia(N...Saad et al.'s review~([1]),“Emerging trends in the management of non-obstructive azoospermia,”offers a compelling synthesis of cutting-edge diagnostic and therapeutic strategies for non-obstructive azoospermia(NOA),a challenging condition affecting 10%–15%o infertile men.By highlighting advances in whole exome sequencing(WES),biomarkers like Anti-Müllerian hormone(AMH)and microRNAs(miRNAs),and microdissection testicular sperm extraction(micro-TESE),the authors chart a path toward precision medicine in male infertility.Their exploration of AI and gene-editing technologies like CRISPR/Cas9 underscores the transformative potential of these innovations.展开更多
文摘Saad et al.'s review~([1]),“Emerging trends in the management of non-obstructive azoospermia,”offers a compelling synthesis of cutting-edge diagnostic and therapeutic strategies for non-obstructive azoospermia(NOA),a challenging condition affecting 10%–15%o infertile men.By highlighting advances in whole exome sequencing(WES),biomarkers like Anti-Müllerian hormone(AMH)and microRNAs(miRNAs),and microdissection testicular sperm extraction(micro-TESE),the authors chart a path toward precision medicine in male infertility.Their exploration of AI and gene-editing technologies like CRISPR/Cas9 underscores the transformative potential of these innovations.