The objectives of this article are as follows: 1) to propose a university research ethics system framework, 2) to provide a brief anatomy of the Meru University of Science and Technology (MUST) Institutional Research ...The objectives of this article are as follows: 1) to propose a university research ethics system framework, 2) to provide a brief anatomy of the Meru University of Science and Technology (MUST) Institutional Research Ethics Review Committee (MIRERC), 3) to perform a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis of MIRERC, and 4) to make recommendations for improving its performance. The 13-member multi-disciplinary MIRERC was established in April 2017 to provide effective ethical oversight of research undertaken by the University’s scholarly community. Strengths of the MUST research ethics review system include a functional MIRERC, a pertinent national law and ethical guidelines, an Innovation and Enterprise Centre that could house a dedicated MIRERC Secretariat, and a supportive University Management Board. The weaknesses include lack of graduate schools to assure scientific rigor of proposals before submission to the MIRERC, lack of research ethics training in most school’s curricula, absence of a dedicated MIRERC Secretariat, undergraduate research proposals being not ethically reviewed, dearth of faculty trained in research ethics, and lack of an operating budget for MIRERC work. The opportunities include existence of about 22 accredited Institutional Research Ethics Review Committees (IRERC) in Kenya, existence of international standards and operational guidance for ethics review, availability of guidelines and codes of best ethical practices in research, existence of a free automated platform called Research for Health Innovation Organizer (RHInnO) Ethics for managing the ethics review process, and availability of external resources for strengthening IRERCs. In order to improve the performance and sustainability of the MUST research ethics system, there is need to include research ethics training in all undergraduate and post-graduate curricula, create a dynamic database of potential research ethics reviewers, allocate a percentage of the annual MUST research budget for MIRERC operations, charge a graduated fee for proposal ethics review, require all students’ and faculties’ internal and external research proposals be cleared by the MIRERC, and use the RHInnO Ethics platform to manage the ethics review process.展开更多
【目的】明确引起禾花鲤发生暴发性死亡征的病原菌及其耐药性,为有效防控禾花鲤暴发性死亡征提供科学依据。【方法】采用常规方法分离病原菌,以API 20NE生化鉴定与16S r RNA基因序列分析相结合的方法进行鉴定,人工回归感染试验确定分离...【目的】明确引起禾花鲤发生暴发性死亡征的病原菌及其耐药性,为有效防控禾花鲤暴发性死亡征提供科学依据。【方法】采用常规方法分离病原菌,以API 20NE生化鉴定与16S r RNA基因序列分析相结合的方法进行鉴定,人工回归感染试验确定分离菌株的致病性,K-B纸片扩散法测定病原菌对药物的敏感性。【结果】从广西全州县患暴发性死亡征禾花鲤的肝脏中分离获得1株优势菌株(TH5),API 20NE生化鉴定和16S r RNA基因序列分析结果显示,分离菌株TH5为简达气单胞菌(Aeromonas jandaei),与简达气单胞菌标准菌株ATCC 49568(NR 119040)和CDC0787-80(NR 037013)的相似度分别为99.9%和99.6%。人工回归感染试验结果表明,菌株TH5是导致禾花鲤暴发性死亡征的病原菌。该菌株对复方新诺明、环丙沙星、多粘菌素B等11种药物高度敏感,对青霉素G、复达欣、先锋霉素VI等8种药物已产生耐药性。【结论】引起广西全州县养殖禾花鲤暴发性死亡征的病原菌是简达气单胞菌,生产中可选用复方新诺明、环丙沙星、多粘菌素B等药物进行防治。展开更多
Drought is the most common of all natural disasters in Kenya, in terms of the large areas covered, populations adversely affected and socio-economic impacts. The Upper Ewaso Ng’iro Basin of Kenya is a drought-prone z...Drought is the most common of all natural disasters in Kenya, in terms of the large areas covered, populations adversely affected and socio-economic impacts. The Upper Ewaso Ng’iro Basin of Kenya is a drought-prone zone, lying on the lee slopes of both Mt. Kenya and Aberdares range. This study sought to determine opinions of communities on drought and its impacts on their livelihoods. Baseline data were collected from published reports and literature reviews augmented with information gathered through interviews with communities and key informants. Field data were collected mainly in the three counties of Laikipia, Isiolo and Meru, utilizing semi-structured questionnaire surveys. A total of 187 respondents were interviewed of which 150 were community members and 37 were policy makers. The typologies of community respondents interviewed included small-scale farmers, large commercial farmers, pastoralists, conservancies, water user associations and conservation groups. It was found that drought is a serious disaster in the Upper Ewaso Ng’iro basin, which has been escalating. Communities experienced negative impacts of drought, with the biggest problem being water scarcity, closely followed by food and fodder shortages and poor incomes from farming. Other problems include spikes in livestock theft, loss of livestock from diseases and shortage of pasture. Conflicts over water and pasture escalate during droughts and crime increases due to lack of on-farm employment opportunities. Since drought events are natural phenomena expected to happen any time, there is need to identify how to improve local capacities in drought preparedness, adaptation and resilience.展开更多
文摘The objectives of this article are as follows: 1) to propose a university research ethics system framework, 2) to provide a brief anatomy of the Meru University of Science and Technology (MUST) Institutional Research Ethics Review Committee (MIRERC), 3) to perform a SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis of MIRERC, and 4) to make recommendations for improving its performance. The 13-member multi-disciplinary MIRERC was established in April 2017 to provide effective ethical oversight of research undertaken by the University’s scholarly community. Strengths of the MUST research ethics review system include a functional MIRERC, a pertinent national law and ethical guidelines, an Innovation and Enterprise Centre that could house a dedicated MIRERC Secretariat, and a supportive University Management Board. The weaknesses include lack of graduate schools to assure scientific rigor of proposals before submission to the MIRERC, lack of research ethics training in most school’s curricula, absence of a dedicated MIRERC Secretariat, undergraduate research proposals being not ethically reviewed, dearth of faculty trained in research ethics, and lack of an operating budget for MIRERC work. The opportunities include existence of about 22 accredited Institutional Research Ethics Review Committees (IRERC) in Kenya, existence of international standards and operational guidance for ethics review, availability of guidelines and codes of best ethical practices in research, existence of a free automated platform called Research for Health Innovation Organizer (RHInnO) Ethics for managing the ethics review process, and availability of external resources for strengthening IRERCs. In order to improve the performance and sustainability of the MUST research ethics system, there is need to include research ethics training in all undergraduate and post-graduate curricula, create a dynamic database of potential research ethics reviewers, allocate a percentage of the annual MUST research budget for MIRERC operations, charge a graduated fee for proposal ethics review, require all students’ and faculties’ internal and external research proposals be cleared by the MIRERC, and use the RHInnO Ethics platform to manage the ethics review process.
文摘Drought is the most common of all natural disasters in Kenya, in terms of the large areas covered, populations adversely affected and socio-economic impacts. The Upper Ewaso Ng’iro Basin of Kenya is a drought-prone zone, lying on the lee slopes of both Mt. Kenya and Aberdares range. This study sought to determine opinions of communities on drought and its impacts on their livelihoods. Baseline data were collected from published reports and literature reviews augmented with information gathered through interviews with communities and key informants. Field data were collected mainly in the three counties of Laikipia, Isiolo and Meru, utilizing semi-structured questionnaire surveys. A total of 187 respondents were interviewed of which 150 were community members and 37 were policy makers. The typologies of community respondents interviewed included small-scale farmers, large commercial farmers, pastoralists, conservancies, water user associations and conservation groups. It was found that drought is a serious disaster in the Upper Ewaso Ng’iro basin, which has been escalating. Communities experienced negative impacts of drought, with the biggest problem being water scarcity, closely followed by food and fodder shortages and poor incomes from farming. Other problems include spikes in livestock theft, loss of livestock from diseases and shortage of pasture. Conflicts over water and pasture escalate during droughts and crime increases due to lack of on-farm employment opportunities. Since drought events are natural phenomena expected to happen any time, there is need to identify how to improve local capacities in drought preparedness, adaptation and resilience.