In order to achieve accurate recovery signals under the underdetermined circumstance in a comparatively short time,an algorithm based on plane pursuit(PP) is proposed. The proposed algorithm selects the atoms accordin...In order to achieve accurate recovery signals under the underdetermined circumstance in a comparatively short time,an algorithm based on plane pursuit(PP) is proposed. The proposed algorithm selects the atoms according to the correlation between received signals and hyper planes, which are composed by column vectors of the mixing matrix, and uses these atoms to recover source signals. Simulation results demonstrate that the PP algorithm has low complexity and higher accuracy as compared with basic pursuit(BP), orthogonal matching pursuit(OMP), and adaptive sparsity matching pursuit(ASMP) algorithms.展开更多
A quasi physical algorithm was proposed for solving the linear separation problem of point set in n dimensional space.The original idea of the quasi physical algorithm is to find an equivalent physical world for the p...A quasi physical algorithm was proposed for solving the linear separation problem of point set in n dimensional space.The original idea of the quasi physical algorithm is to find an equivalent physical world for the primitive mathematical problem and to observe the vivid images of the motion of matter in it so as to be inspired to obtain an algorithm for solving the mathematical problem. In this work, the electrostatics with two kinds of matter is found to be the equivalent physical world. As a result,the proposed algorithm is evidently more efficient and robust than the famous LMS algorithm and ETL algorithm. The efficiency of the quasi physical algorithm is about 10-50 times of the LMS algorithm’s for representative instances. A typical Boolean valued instance shows that it is hard for ETL algorithm but very easy for the quasi physical algorithm.In this instance, point set A and B is {000, 010, 011, 111} and {001,100}, respectively.展开更多
This paper presents a flexible model and a robust algorithm for simulation of multi-stage multi-component separation processes in which multiple feeds, side streams, strippers and/or side heat exchangers are involved....This paper presents a flexible model and a robust algorithm for simulation of multi-stage multi-component separation processes in which multiple feeds, side streams, strippers and/or side heat exchangers are involved. The improved algorithm effectively accelerates the speed of convergence and offers better stability by introducing a damping factor for updating the stripping factor, and also reduces the requirement on the initial estimates by updating the Joacobian matrix directly with the stripping factor and enthalpy. On the other hand, an efficient algorithm was proposed to solve the approximate tri-diagonal matrix (containing the off-band elements) derived from the material balance equations (M equations) and phase equilibrium equations (E equations), the advantages and simplicity of the “insideout” technique of the Russell are retained. The present algorithm was demonstrated to be effective in simulating complex separation columns with typical case studies.展开更多
Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability o...Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability of separating mixed signals in complex electromagnetic environment,a blind source separa-tion algorithm based on degree of cyclostationarity(DCS)crite-rion is constructed in this paper.Firstly,the DCS criterion is con-structed by using the cyclic spectrum theory.Then the algo-rithm flow of blind source separation is designed based on DCS criterion.At the same time,Givens matrix is constructed to make the blind source separation algorithm suitable for multiple sig-nals with different cyclostationary frequencies.The feasibility of this method is further proved.The theoretical and simulation results show that the algorithm can effectively separate and re-cognize common multi-radar signals.展开更多
This letter proposes two algorithms: a novel Quantum Genetic Algorithm (QGA)based on the improvement of Han's Genetic Quantum Algorithm (GQA) and a new Blind Source Separation (BSS) method based on QGA and Indepen...This letter proposes two algorithms: a novel Quantum Genetic Algorithm (QGA)based on the improvement of Han's Genetic Quantum Algorithm (GQA) and a new Blind Source Separation (BSS) method based on QGA and Independent Component Analysis (ICA). The simulation result shows that the efficiency of the new BSS method is obviously higher than that of the Conventional Genetic Algorithm (CGA).展开更多
This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification ...This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification of distillation processes,optimization of process parameters for distillation processes and recent research progress in dynamic control strategies.Firstly,the feasibility of using thermodynamic topological theories such as residual curve,phase equilibrium line and distillation boundary line to analyze different separation regions is discussed,and the rationality of distillation process design is discussed by using its feasibility.Secondly,the application of molecular simulation methods such as molecular dynamics simulation and quantum chemical calculation in the screening of entrainer is discussed for the extractive distillation process.The thermal coupling mechanism of different distillation processes is used to explore the process of different process intensifications.Next,a mixed integer nonlinear optimization strategy for the distillation process based on different algorithms is introduced.Finally,the improvement of dynamic control strategies for different distillation processes in recent years is summarized.This work focuses on the application of process intensification and system optimization in the design of distillation process,and analyzes the challenges,prospects,and development trends of distillation technology in the separation of multicomponent azeotropes.展开更多
In general conditions, most blind source separation algorithms are established on noisy-free model and ignore the noise that affects the quality of separated sources. Firstly, this paper introduces an improved natural...In general conditions, most blind source separation algorithms are established on noisy-free model and ignore the noise that affects the quality of separated sources. Firstly, this paper introduces an improved natural gradient algorithm based on bias removal technology to estimate the demixing matrix under noisy environment. Then the discrete wavelet transform technology is applied to the separated signals to further remove noise. In order to improve the separation effect, this paper analyzes the deficiency of hard threshold and soft threshold, and proposes a new wavelet threshold function based on the wavelet decomposition and reconfiguration. The simulations have verified that this method improves the signal noise ratio （SNR） of the separation results and the separation precision.展开更多
In LEO satellite communication networks,the number of satellites has increased sharply, the relative velocity of satellites is very fast, then electronic signal aliasing occurs from time to time. Those aliasing signal...In LEO satellite communication networks,the number of satellites has increased sharply, the relative velocity of satellites is very fast, then electronic signal aliasing occurs from time to time. Those aliasing signals make the receiving ability of the signal receiver worse, the signal processing ability weaker,and the anti-interference ability of the communication system lower. Aiming at the above problems, to save communication resources and improve communication efficiency, and considering the irregularity of interference signals, the underdetermined blind separation technology can effectively deal with the problem of interference sensing and signal reconstruction in this scenario. In order to improve the stability of source signal separation and the security of information transmission, a greedy optimization algorithm can be executed. At the same time, to improve network information transmission efficiency and prevent algorithms from getting trapped in local optima, delete low-energy points during each iteration process. Ultimately, simulation experiments validate that the algorithm presented in this paper enhances both the transmission efficiency of the network transmission system and the security of the communication system, achieving the process of interference sensing and signal reconstruction in the LEO satellite communication system.展开更多
An algorithm capable of predicting and optimizing the gradient separation of LC×LC system was developed in this paper.Two groups of structural analogues,five ginsenosides as well as eight bisphenols,which were di...An algorithm capable of predicting and optimizing the gradient separation of LC×LC system was developed in this paper.Two groups of structural analogues,five ginsenosides as well as eight bisphenols,which were difficult to discriminate in routine analysis,were used to verify the effectiveness of the proposed algorithm in fast separation optimization.Average errors of retention times below 1%were found in the retention prediction for all types of gradient programs,implying that the theory could lead to high quality in prediction of the retention times under gradients elution.Meanwhile,84%of relative average deviations(RADs)between the predicted peak width and the measured ones were less than 20%.The larger deviation occurred at the time when the peak appeared while the gradient of the mobile phase changed,which led the deviations increased to 20%–42%.In all,method development and optimization for LC×LC tandem system was realized by the homemade user-friendly software.The present protocol may turn on great opportunities for the convenient method development in analysis of trace structural analogues in environmental,food and biological samples.展开更多
Evolutionary algorithm is applied for distillation separation sequence optimization synthesis problems with combination explosion. The binary tree data structure is used to describe the distillation separation sequenc...Evolutionary algorithm is applied for distillation separation sequence optimization synthesis problems with combination explosion. The binary tree data structure is used to describe the distillation separation sequence, and it is directly applied as the coding method. Genetic operators, which ensure to prohibit illegal filial generations completely, are designed by using the method of graph theory. The crossover operator based on a single parent or two parents is designed successfully. The example shows that the average ratio of search space from evolutionary algorithm with two-parent genetic operation is lower, whereas the rate of successful minimizations from evolutionary algorithm with single parent genetic operation is higher.展开更多
There are two major approaches for Blind Signal Separation (BSS) problem: Maximum Entropy (ME) and Minimum Mutual Information (MMI) algorithms. Based on the recursive architecture and the relationship between the ME a...There are two major approaches for Blind Signal Separation (BSS) problem: Maximum Entropy (ME) and Minimum Mutual Information (MMI) algorithms. Based on the recursive architecture and the relationship between the ME and MMI algorithms, an Extended ME(EME) algorithm is proposed by using probability density function (pdf) estimation of the outputs to deduce the corresponding iterative formulas in BSS. Based on the simulation results, it can be concluded that the proposed algorithm has better performances than the traditional ME algorithm in convolute mixture BSS problems.展开更多
The transient critical boundary of dynamic security region (DSR) can be approximated by a few hyper planes correlated with instability separation modes. A method to fast predict instability separation modes is propose...The transient critical boundary of dynamic security region (DSR) can be approximated by a few hyper planes correlated with instability separation modes. A method to fast predict instability separation modes is proposed for DSR calculation in power injection space. The method identifies coherent generation groups by the developed K-medoids algorithm, taking a similarity matrix derived from the reachability Grammian as the index. As an experimental result, reachability Grammian matrices under local injections are approximately invariant. It indicates that the generator coherency identifications are nearly consistent for different injections. Then instability separation modes can be predicted at the normal operating point, while average initial acceleration is considered as the measure of the critical generator group to amend the error. Moreover, based on these predicted instability separation modes, a critical point search strategy for DSR calculation is illustrated in the reduced injection space of the critical generators. The proposed method was evaluated using New England Test System, and the computation accuracy and speed in determining the practical DSR were improved.展开更多
As the current calculation methods for wellbore separation factor have some deficiencies, we propose and analyze a new calculation approach for wellbore separation factor based on the relative position of adjacent wel...As the current calculation methods for wellbore separation factor have some deficiencies, we propose and analyze a new calculation approach for wellbore separation factor based on the relative position of adjacent wellbores, named as relative position method for short. Based on the trajectory error ellipsoid model of single wellbore, the error ellipsoids model of adjacent wellbore was derived considering the correlation of trajectory errors between adjacent wells. Furthermore, the calculation formula of the separation factor based on relative position of adjacent wellbore was derived and solved with the conjugate gradient algorithm. Case study shows that the new approach is more precise and higher in applicability than the ellipsoid scaling method and the minimum distance method, it can evaluate the state of well collision more reasonably. By doing batch calculation with the new method and following the criterion of well collision avoidance, the permissible ranges of key parameters in the well design can be worked out quickly. This method has good application in the design of cluster wells and directional wells.展开更多
Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics,such as the changes of cerebral blood flow,perfusion or oxygen con-centration in arteries an...Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics,such as the changes of cerebral blood flow,perfusion or oxygen con-centration in arteries and veins under different pathological and physiological conditions.Yet the cerebral vessel segmentation and vessel-type separation are challenging due to the complexity of cortical vessel characteristics and low spatial signal-to-noise ratio.In this work,we presented an effective full-field method to differentiate arteries and veins in cerebral cortex using dual-modal optical imaging technology including laser speckle imaging(LSI)and optical intrinsic signals(OIS)imaging.The raw contrast images were acquired by LSI and processed with enhanced laser speckle contrast analysis(eLASCA),algorithm.The vascular pattern was extracted and seg-mented using region growing algorithm from the eLASCA-based LSI.Meanwhile,OIS imageswere acquired altermatively with 630 and 870 nm to obtain an oxy hemoglobin concentration mapover cerebral cortex.Then the separation of arteries and veins was accomplished by Otsuthreshold segmentation algorithm based on the OIS information and segmentation of LSI.Finally,the segmentation and separation performances were assessed using area overlap measure(AOM).The segmentation and separation of cerebral vessels in cortical optical imaging have great potential applications in full-field cerebral hemodynamics monitoring and pathological study of cerebral vascular diseases,as well as in clinical intraoperative monitoring.展开更多
This paper focuses primarily on exploring the application of deep learning techniques and image processing algorithms in immunohistochemistry analysis,specifically targeting automated quantitative methods for nu-clear...This paper focuses primarily on exploring the application of deep learning techniques and image processing algorithms in immunohistochemistry analysis,specifically targeting automated quantitative methods for nu-clear,membrane,and cytoplasmic expressions of animal cells in whole-slide images.Cell nuclei,membranes,and cytoplasm were precisely identified and quantified by employing optical density separation techniques to differentiate between hematoxylin and 3,3'-diaminobenzidine staining components in combination with the CellViT nuclear segmentation algorithm and the region growing algorithm.Experimental validation demon-strates that the proposed algorithm performs excellently in terms of accuracy and recall.Compared to traditional manual interpretation,this algorithm achieve greater accuracy in specific quantitative metrics.展开更多
A learning algorithm based on a hard limiter for feedforward neural networks (NN) is presented,and is applied in solving classification problems on separable convex sets and disjoint sets.It has been proved that the a...A learning algorithm based on a hard limiter for feedforward neural networks (NN) is presented,and is applied in solving classification problems on separable convex sets and disjoint sets.It has been proved that the algorithm has stronger classification ability than that of the back propagation (BP) algorithm for the feedforward NN using sigmoid function by simulation.What is more,the models can be implemented with lower cost hardware than that of the BP NN.LEARNIN展开更多
基金supported by the National Natural Science Foundation of China(61201134)the 111 Project(B08038)
文摘In order to achieve accurate recovery signals under the underdetermined circumstance in a comparatively short time,an algorithm based on plane pursuit(PP) is proposed. The proposed algorithm selects the atoms according to the correlation between received signals and hyper planes, which are composed by column vectors of the mixing matrix, and uses these atoms to recover source signals. Simulation results demonstrate that the PP algorithm has low complexity and higher accuracy as compared with basic pursuit(BP), orthogonal matching pursuit(OMP), and adaptive sparsity matching pursuit(ASMP) algorithms.
基金TheNationalKeyBasicResearchProgram (973) (No .G 19980 30 6 0 0 )
文摘A quasi physical algorithm was proposed for solving the linear separation problem of point set in n dimensional space.The original idea of the quasi physical algorithm is to find an equivalent physical world for the primitive mathematical problem and to observe the vivid images of the motion of matter in it so as to be inspired to obtain an algorithm for solving the mathematical problem. In this work, the electrostatics with two kinds of matter is found to be the equivalent physical world. As a result,the proposed algorithm is evidently more efficient and robust than the famous LMS algorithm and ETL algorithm. The efficiency of the quasi physical algorithm is about 10-50 times of the LMS algorithm’s for representative instances. A typical Boolean valued instance shows that it is hard for ETL algorithm but very easy for the quasi physical algorithm.In this instance, point set A and B is {000, 010, 011, 111} and {001,100}, respectively.
文摘This paper presents a flexible model and a robust algorithm for simulation of multi-stage multi-component separation processes in which multiple feeds, side streams, strippers and/or side heat exchangers are involved. The improved algorithm effectively accelerates the speed of convergence and offers better stability by introducing a damping factor for updating the stripping factor, and also reduces the requirement on the initial estimates by updating the Joacobian matrix directly with the stripping factor and enthalpy. On the other hand, an efficient algorithm was proposed to solve the approximate tri-diagonal matrix (containing the off-band elements) derived from the material balance equations (M equations) and phase equilibrium equations (E equations), the advantages and simplicity of the “insideout” technique of the Russell are retained. The present algorithm was demonstrated to be effective in simulating complex separation columns with typical case studies.
基金supported by the National Natural Science Foundation of China(61502522).
文摘Separation and recognition of radar signals is the key function of modern radar reconnaissance,which is of great sig-nificance for electronic countermeasures and anti-countermea-sures.In order to improve the ability of separating mixed signals in complex electromagnetic environment,a blind source separa-tion algorithm based on degree of cyclostationarity(DCS)crite-rion is constructed in this paper.Firstly,the DCS criterion is con-structed by using the cyclic spectrum theory.Then the algo-rithm flow of blind source separation is designed based on DCS criterion.At the same time,Givens matrix is constructed to make the blind source separation algorithm suitable for multiple sig-nals with different cyclostationary frequencies.The feasibility of this method is further proved.The theoretical and simulation results show that the algorithm can effectively separate and re-cognize common multi-radar signals.
基金Supported by the National Natural Science Foundation of China (No.60171029)
文摘This letter proposes two algorithms: a novel Quantum Genetic Algorithm (QGA)based on the improvement of Han's Genetic Quantum Algorithm (GQA) and a new Blind Source Separation (BSS) method based on QGA and Independent Component Analysis (ICA). The simulation result shows that the efficiency of the new BSS method is obviously higher than that of the Conventional Genetic Algorithm (CGA).
文摘This work provides an overview of distillation processes,including process design for different distillation processes,selection of entrainers for special distillation processes,system integration and intensification of distillation processes,optimization of process parameters for distillation processes and recent research progress in dynamic control strategies.Firstly,the feasibility of using thermodynamic topological theories such as residual curve,phase equilibrium line and distillation boundary line to analyze different separation regions is discussed,and the rationality of distillation process design is discussed by using its feasibility.Secondly,the application of molecular simulation methods such as molecular dynamics simulation and quantum chemical calculation in the screening of entrainer is discussed for the extractive distillation process.The thermal coupling mechanism of different distillation processes is used to explore the process of different process intensifications.Next,a mixed integer nonlinear optimization strategy for the distillation process based on different algorithms is introduced.Finally,the improvement of dynamic control strategies for different distillation processes in recent years is summarized.This work focuses on the application of process intensification and system optimization in the design of distillation process,and analyzes the challenges,prospects,and development trends of distillation technology in the separation of multicomponent azeotropes.
基金supported by the Key Item of Science and Technology Program of Xiangtan City,Hunan Province,China under Grant No. ZJ20071008
文摘In general conditions, most blind source separation algorithms are established on noisy-free model and ignore the noise that affects the quality of separated sources. Firstly, this paper introduces an improved natural gradient algorithm based on bias removal technology to estimate the demixing matrix under noisy environment. Then the discrete wavelet transform technology is applied to the separated signals to further remove noise. In order to improve the separation effect, this paper analyzes the deficiency of hard threshold and soft threshold, and proposes a new wavelet threshold function based on the wavelet decomposition and reconfiguration. The simulations have verified that this method improves the signal noise ratio （SNR） of the separation results and the separation precision.
基金supported by National Natural Science Foundation of China (62171390)Central Universities of Southwest Minzu University (ZYN2022032,2023NYXXS034)the State Scholarship Fund of the China Scholarship Council (NO.202008510081)。
文摘In LEO satellite communication networks,the number of satellites has increased sharply, the relative velocity of satellites is very fast, then electronic signal aliasing occurs from time to time. Those aliasing signals make the receiving ability of the signal receiver worse, the signal processing ability weaker,and the anti-interference ability of the communication system lower. Aiming at the above problems, to save communication resources and improve communication efficiency, and considering the irregularity of interference signals, the underdetermined blind separation technology can effectively deal with the problem of interference sensing and signal reconstruction in this scenario. In order to improve the stability of source signal separation and the security of information transmission, a greedy optimization algorithm can be executed. At the same time, to improve network information transmission efficiency and prevent algorithms from getting trapped in local optima, delete low-energy points during each iteration process. Ultimately, simulation experiments validate that the algorithm presented in this paper enhances both the transmission efficiency of the network transmission system and the security of the communication system, achieving the process of interference sensing and signal reconstruction in the LEO satellite communication system.
基金supported by National Natural Science Foundation of China(Nos.82174090,22176085,21874065,21577057)Natural Science Foundation for Colleges of Jiangsu(No.21KJA360007)+2 种基金Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Jiangsu Qinglan ProjectJiangsu“333”Project。
文摘An algorithm capable of predicting and optimizing the gradient separation of LC×LC system was developed in this paper.Two groups of structural analogues,five ginsenosides as well as eight bisphenols,which were difficult to discriminate in routine analysis,were used to verify the effectiveness of the proposed algorithm in fast separation optimization.Average errors of retention times below 1%were found in the retention prediction for all types of gradient programs,implying that the theory could lead to high quality in prediction of the retention times under gradients elution.Meanwhile,84%of relative average deviations(RADs)between the predicted peak width and the measured ones were less than 20%.The larger deviation occurred at the time when the peak appeared while the gradient of the mobile phase changed,which led the deviations increased to 20%–42%.In all,method development and optimization for LC×LC tandem system was realized by the homemade user-friendly software.The present protocol may turn on great opportunities for the convenient method development in analysis of trace structural analogues in environmental,food and biological samples.
文摘Evolutionary algorithm is applied for distillation separation sequence optimization synthesis problems with combination explosion. The binary tree data structure is used to describe the distillation separation sequence, and it is directly applied as the coding method. Genetic operators, which ensure to prohibit illegal filial generations completely, are designed by using the method of graph theory. The crossover operator based on a single parent or two parents is designed successfully. The example shows that the average ratio of search space from evolutionary algorithm with two-parent genetic operation is lower, whereas the rate of successful minimizations from evolutionary algorithm with single parent genetic operation is higher.
文摘There are two major approaches for Blind Signal Separation (BSS) problem: Maximum Entropy (ME) and Minimum Mutual Information (MMI) algorithms. Based on the recursive architecture and the relationship between the ME and MMI algorithms, an Extended ME(EME) algorithm is proposed by using probability density function (pdf) estimation of the outputs to deduce the corresponding iterative formulas in BSS. Based on the simulation results, it can be concluded that the proposed algorithm has better performances than the traditional ME algorithm in convolute mixture BSS problems.
基金Supported by National Natural Science Foundation of China (No.50595413)Special Fund of the National Fundamental Research of China(No.2004CB217904)+4 种基金US EPRI under Agreement EP-P29464/C9966Foundation for the Author of National Excellent Doctoral Disserta-tion (No.200439)Key Project of Ministry of Education of China(No.105047)Program for New Century Excellent Talents in University,Fok Ying Tung Education Foundation (No.104019)Innovation Fund of Tianjin Municipal (2006-09)
文摘The transient critical boundary of dynamic security region (DSR) can be approximated by a few hyper planes correlated with instability separation modes. A method to fast predict instability separation modes is proposed for DSR calculation in power injection space. The method identifies coherent generation groups by the developed K-medoids algorithm, taking a similarity matrix derived from the reachability Grammian as the index. As an experimental result, reachability Grammian matrices under local injections are approximately invariant. It indicates that the generator coherency identifications are nearly consistent for different injections. Then instability separation modes can be predicted at the normal operating point, while average initial acceleration is considered as the measure of the critical generator group to amend the error. Moreover, based on these predicted instability separation modes, a critical point search strategy for DSR calculation is illustrated in the reduced injection space of the critical generators. The proposed method was evaluated using New England Test System, and the computation accuracy and speed in determining the practical DSR were improved.
基金Supported by the Major Program of the Strategic Pilot Science and Technology Foundation of Chinese Academy of Sciences(XDA14020500)the CNPC Science and Technology Major Project(2019A-3912,2018E-2107).
文摘As the current calculation methods for wellbore separation factor have some deficiencies, we propose and analyze a new calculation approach for wellbore separation factor based on the relative position of adjacent wellbores, named as relative position method for short. Based on the trajectory error ellipsoid model of single wellbore, the error ellipsoids model of adjacent wellbore was derived considering the correlation of trajectory errors between adjacent wells. Furthermore, the calculation formula of the separation factor based on relative position of adjacent wellbore was derived and solved with the conjugate gradient algorithm. Case study shows that the new approach is more precise and higher in applicability than the ellipsoid scaling method and the minimum distance method, it can evaluate the state of well collision more reasonably. By doing batch calculation with the new method and following the criterion of well collision avoidance, the permissible ranges of key parameters in the well design can be worked out quickly. This method has good application in the design of cluster wells and directional wells.
文摘Separation of arteries and veins in the cerebral cortex is of significant importance in the studies of cortical hemodynamics,such as the changes of cerebral blood flow,perfusion or oxygen con-centration in arteries and veins under different pathological and physiological conditions.Yet the cerebral vessel segmentation and vessel-type separation are challenging due to the complexity of cortical vessel characteristics and low spatial signal-to-noise ratio.In this work,we presented an effective full-field method to differentiate arteries and veins in cerebral cortex using dual-modal optical imaging technology including laser speckle imaging(LSI)and optical intrinsic signals(OIS)imaging.The raw contrast images were acquired by LSI and processed with enhanced laser speckle contrast analysis(eLASCA),algorithm.The vascular pattern was extracted and seg-mented using region growing algorithm from the eLASCA-based LSI.Meanwhile,OIS imageswere acquired altermatively with 630 and 870 nm to obtain an oxy hemoglobin concentration mapover cerebral cortex.Then the separation of arteries and veins was accomplished by Otsuthreshold segmentation algorithm based on the OIS information and segmentation of LSI.Finally,the segmentation and separation performances were assessed using area overlap measure(AOM).The segmentation and separation of cerebral vessels in cortical optical imaging have great potential applications in full-field cerebral hemodynamics monitoring and pathological study of cerebral vascular diseases,as well as in clinical intraoperative monitoring.
文摘This paper focuses primarily on exploring the application of deep learning techniques and image processing algorithms in immunohistochemistry analysis,specifically targeting automated quantitative methods for nu-clear,membrane,and cytoplasmic expressions of animal cells in whole-slide images.Cell nuclei,membranes,and cytoplasm were precisely identified and quantified by employing optical density separation techniques to differentiate between hematoxylin and 3,3'-diaminobenzidine staining components in combination with the CellViT nuclear segmentation algorithm and the region growing algorithm.Experimental validation demon-strates that the proposed algorithm performs excellently in terms of accuracy and recall.Compared to traditional manual interpretation,this algorithm achieve greater accuracy in specific quantitative metrics.
文摘A learning algorithm based on a hard limiter for feedforward neural networks (NN) is presented,and is applied in solving classification problems on separable convex sets and disjoint sets.It has been proved that the algorithm has stronger classification ability than that of the back propagation (BP) algorithm for the feedforward NN using sigmoid function by simulation.What is more,the models can be implemented with lower cost hardware than that of the BP NN.LEARNIN
