[ Objective ] The paper was to study the effect of controlled atmosphere stress of carbon dioxide （ CO2 ） on Superoxide dismutase （SOD） activity of in- sect, so as to analyze the biological mechanism of the action...[ Objective ] The paper was to study the effect of controlled atmosphere stress of carbon dioxide （ CO2 ） on Superoxide dismutase （SOD） activity of in- sect, so as to analyze the biological mechanism of the action of controlled atmosphere stress on insect. [ Method] Using nitrotetrazolium blue chloride （NBT） light reduction method, SOD activity of drugstore beetle （ Stegobium panlceum ）, cigarette beetle （ Lasioderma serricorne） and coffee bean beetle （Araecerus fasciculatus） was studied, and the stress response of the enzyme under controlled atmosphere stress of CO2 was analyzed. [ Result ] SOD activity of drugstore beetle, cigarette beetle and coffee bean beetle exposed to controlled atmosphere stress of high concentrations of CO2 for 3 and 6 h had certain degree of increase, and the activity sig- nificantly increased from 2.011±0.954,2.664±0.218 and 1.458±0.718 to 3. 135±0. 105,3.050±0.673 and 2.975±0.229 U/（per pest · 30 min） after treat- ment for 6 h. [ Conclusion] Controlled atmosphere stress of high concentrations of CO2 had certain activation effect on SOD activity of storage pest in Chinese me- dicinal material within the context of sub-lethal events. The results could enrich the insecticidal mechanism of controlled atmosphere and theoretical system of analy- sis on insect resistance to controlled atmosphere.展开更多
First of all,this paper introduces the concept,traditional and modern evaluation and conditions of genuine medicinal materials.It focuses on the current situation of genuine medicinal materials in Xinjiang,and suggest...First of all,this paper introduces the concept,traditional and modern evaluation and conditions of genuine medicinal materials.It focuses on the current situation of genuine medicinal materials in Xinjiang,and suggests that we should strengthen the development,utilization and protection of genuine medicinal resources in Xinjiang from a professional point of view.展开更多
In recent years,the price of traditional Chinese medicinal materials soars continuously,and the resulting price risk increasingly looms large,which has critically affected midstream and downstream industries and peopl...In recent years,the price of traditional Chinese medicinal materials soars continuously,and the resulting price risk increasingly looms large,which has critically affected midstream and downstream industries and peoples' demand for drug,and imperiled healthy and orderly development of traditional Chinese medicinal industries.Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present,we winkle out the root cause of soaring price as follows:the supply and demand lose balance;the production costs hike up;there are other factors responsible for soaring price.This paper further analyses the impact of sharp increase in price of traditional Chinese medicinal materials on all links of industry chain as follows:the medicinal herb growers never benefit from soaring price;the counterfeiters and forgers in midstream industry increase;the gross profit rate of Chinese medicine enterprises declines.In accordance with the risk arising from abnormal fluctuation in price of traditional Chinese medicinal materials,corresponding precautionary measures are put forward as follows:promote the quality of traditional Chinese medicinal materials through management of value chain;curtail the production and management cost of traditional Chinese medicinal materials through management of organization chain;stabilize price of traditional Chinese medicinal materials through management of information chain;reduce transaction cost of traditional Chinese medicinal materials through management of logistics chain.展开更多
The paper summarized the effects of soil on the quality of Chinese medicinal materials from the aspects of physical,chemical and biological properties of soil,in order to provide a reference for further research on th...The paper summarized the effects of soil on the quality of Chinese medicinal materials from the aspects of physical,chemical and biological properties of soil,in order to provide a reference for further research on the internal relationship between soil factors and the quality of Chinese medicinal materials,and to provide a theoretical basis for the cultivation and quality improvement of Chinese medicinal materials.展开更多
Through the analysis on the cultivation advantages and development problems of traditional Chinese medicinal planting industry in Shiyan City, Hubei Province, some measures were proposed to enlarge and enhance the tra...Through the analysis on the cultivation advantages and development problems of traditional Chinese medicinal planting industry in Shiyan City, Hubei Province, some measures were proposed to enlarge and enhance the traditional Chinese medicinal planting industry, namely, large-scale, standardized, market-oriented and regionalized planting, thereby making it the pillar industry for farmers to increase income.展开更多
Breast cancer is globally the most common invasive cancer in women and remains one of the leading causes of cancer-related deaths.Surgery,radiotherapy,chemotherapy,immunotherapy,and endocrine therapy are currently the...Breast cancer is globally the most common invasive cancer in women and remains one of the leading causes of cancer-related deaths.Surgery,radiotherapy,chemotherapy,immunotherapy,and endocrine therapy are currently the main treatments for this cancer type.However,some breast cancer patients are prone to drug resistance related to chemotherapy or immunotherapy,resulting in limited treatment efficacy.Consequently,traditional Chinese medicinal materials(TCMMs)as natural products have become an attractive source of novel drugs.In this review,we summarized the current knowledge on the active components of animal-derived TCMMs,including Ophiocordyceps sinensis-derived cordycepin,the aqueous and ethanolic extracts of O.sinensis,norcantharidin(NCTD),Chansu,bee venom,deer antlers,Ostrea gigas,and scorpion venom,with reference to marked anti-breast cancer effects due to regulating cell cycle arrest,proliferation,apoptosis,metastasis,and drug resistance.In future studies,the underlying mechanisms for the antitumor effects of these components need to be further investigated by utilizing multi-omics technologies.Furthermore,large-scale clinical trials are necessary to validate the efficacy of bioactive constituents alone or in combination with chemotherapeutic drugs for breast cancer treatment.展开更多
In order to promote the standardization of production and processing of medicinal materials of animal-derivative,on January 15,2024,the China Association of Chinese Medicine approved and released the group standards(T...In order to promote the standardization of production and processing of medicinal materials of animal-derivative,on January 15,2024,the China Association of Chinese Medicine approved and released the group standards(T/CACM 1571.1-2024T/CACM 1571.16-2024).Among them,the“Technical code of practice for production and processing of medicinal materials of animalderivative—General rules”(T/CACM 1571.1-2024)(hereinafter referred to as the“General rules”)serves as the overarching guide for the series of specifications.This article provides a detailed interpretation of the“General rules”in order to facilitate the implementation of“Technical code of practice for production and processing of medicinal materials of animal-derivative”and to advance the standardized production of medicinal materials of animal-derivative.展开更多
As the national Chinese medicine market develops,Chinese medicinal materials price index(CMMPI)trend is worthy of attention.Predicting future CMMPI trend plays a significant role in risk prevention,cultivation,and tra...As the national Chinese medicine market develops,Chinese medicinal materials price index(CMMPI)trend is worthy of attention.Predicting future CMMPI trend plays a significant role in risk prevention,cultivation,and trade for farmers and investors.This study aims to design a high-precision model to predict the future trend of the CMMPI.The model incorporates environmental factors such as weather conditions and air quality that have a greater impact on the growth of Chinese medical plants and the supply of Chinese medicinal materials market.Specifically,we collected multi-source heterogeneous data,including weather data,air quality data,and historical CMMPI data,to construct informative features.Additionally,we proposed a feature selection method based on the genetic algorithm and XGBoost to select features.Finally,we transferred the selected features to the bidirectional GRU deep learning to realize the accurate prediction of the CMMPI trend.We collected 46 CMMPI datasets to test the proposed model.The results show that the proposed model obtained more superior prediction compared to the state-of-the-art methods,and specialized in predicting long-term goal(90 days).Taking the Yunnan and Xizang origin index as examples,the experiment results also show the weather and air quality data can improve the prediction performance,as these factors are known to influence the growth and market supply of Chinese medicinal materials.展开更多
Traditional Mongolian medicine(TMM)is an important part of Chinese traditional culture,which plays an important role within the medical system of China.The processing of Mongolian medicinal materials is a pharmaceutic...Traditional Mongolian medicine(TMM)is an important part of Chinese traditional culture,which plays an important role within the medical system of China.The processing of Mongolian medicinal materials is a pharmaceutical technology,which is the unique characteristics of Mongolian medicine.In this paper,the basic concepts related to the processing of Mongolian medicinal materials were introduced,and its scientific research points were put forward,in order to deeply excavate the connotation of Mongolian pharmacy and further study the processing mechanism of Mongolian medicinal materials,so as to provide important basis for the development of Chinese traditional medicine.The essence of Mongolian medicinal materials processing is to use drugs safely and dialectically to ensure the quality of Mongolian medicinal materials.The scientific research sites of Mongolian medicinal materials processing have two categories:reducing toxicity(increasing)effect and synergistic effect of excipients and processing factors.Because of the not perfect research platform of Mongolian medicinal materials and the weak processing power,the development of research of Mongolian medicinal materials is relatively slow.Therefore,there are many research breakthroughs in the interdisciplinary research on the processing of Mongolian medicinal materials,and it is expected to become a research hotspot.展开更多
Objective: To analyze the effect of spectrofluorimetry and highperformance liquid chromatography in the detection of aflatoxin in Chinese medicinal materials. Methods: The content of aflatoxin in Chinese medicinal mat...Objective: To analyze the effect of spectrofluorimetry and highperformance liquid chromatography in the detection of aflatoxin in Chinese medicinal materials. Methods: The content of aflatoxin in Chinese medicinal materials was determined by spectrofluorimetry and high-performance liquid chromatography respectively, and the effects of the two detection methods were compared. Results: The results of sample detection by spectrofluorimetry showed that except for Angelica and Sophora flavescens with "detection dada error", the other 25 kinds of Chinese medicinal materials were positive for aflatoxin, but the types of aflatoxin derivatives could not be distinguished, and the tested content was generally high. The recovery experiment of mixed reference substance based on the concentration levels showed that the recovery rate of aflatoxin was 93.60%-99.70% in the case of high-performance liquid chromatography,and the RSD was 1.83%-6.70%. The sample detection results by high-performance liquid chromatography showed that among the 18 kinds of Chinese medicinal materials,only Radix Peucedani, almond, barley, raw Jianqu and aflatoxin were positive, and the types of aflatoxin derivatives could be accurately differentiated. Conclusion: Compared with spectrofluorimetry, high-performance liquid chromatography is more accurate in the determination of aflatoxin content in Chinese medicinal materials, which can distinguish the types of aflatoxin derivatives.展开更多
This paper thoroughly explores the multifaceted factors influencing the efficacy of Chinese medicinals and categorizes them into three main groups:medicinal related factors,patient related factors,and practitioner rel...This paper thoroughly explores the multifaceted factors influencing the efficacy of Chinese medicinals and categorizes them into three main groups:medicinal related factors,patient related factors,and practitioner related factors.Regarding medicinal related factors,the place of origin,growing environment,harvesting time,storage conditions,quality control,dosage form selection,compatibility of medicinals,precise dosing,decoction methods,and administration routes all significantly impact efficacy.The place of origin determines the authenticity of medicinals,the growing environment affects their composition,harvesting time influences potency,improper storage leads to deterioration,quality control forms the foundation of efficacy,dosage forms and compatibility of medicinals affect absorption,dosing and decoction methods require precision,and administration routes should be tailored to individuals.Patient related factors include psychological state,individual differences,background,and disease condition.Psychological state affects treatment compliance,individual differences determine medicine responses,background influences patients’understanding of Chinese medicinals,and disease condition directly reflects efficacy.Practitioner related factors encompass theoretical knowledge,clinical experience,inherited practices,psychological state,and professional ethics.Theoretical knowledge guides medication use,clinical experience enhances efficacy,inherited practices influence prescribing styles,psychological state affects doctor–patient communication,and professional ethics ensure medical quality.These interrelated factors collectively influence the efficacy of Chinese medicinals,emphasizing the need for comprehensive consideration in clinical applications to achieve optimal therapeutic outcomes.展开更多
With sulphur-fumigated Chinese medicinal materials （Fritillaria thunbergii , Isatis #utigotica , Asparagus cochinchinensis and Poria cocos ） as the test materials, sulfur dioxide or sulfite residue was determined by...With sulphur-fumigated Chinese medicinal materials （Fritillaria thunbergii , Isatis #utigotica , Asparagus cochinchinensis and Poria cocos ） as the test materials, sulfur dioxide or sulfite residue was determined by the method in Chinese Pharmacopoeia （2015 edition） and titration-fluorescence spectrometry, respec- tively. The results showed that there were significant differences in measured value between titration-fluorescence spectrometry and phmmacopoeia method. The t result of titration-fluorescence spectrometry was much closer to the actual content of sulfur dioxide in Chinese medicinal materials. Thus, titration-fluo- rescence spectrometry had higher application value展开更多
High-performance liquid chromatography （HPLC） was used to quantify magnaldehyde B （6）, magnaldehyde E （4） and 8＇,9＇-dihydroxyhonokiol （7） simultaneously in the raw Chinese medicinal material honokiol. The se...High-performance liquid chromatography （HPLC） was used to quantify magnaldehyde B （6）, magnaldehyde E （4） and 8＇,9＇-dihydroxyhonokiol （7） simultaneously in the raw Chinese medicinal material honokiol. The separation was performed on a reversed-phase Cl8 column by using a gradient elution with mobile phases of water （A） and methanol （B）. The mobile phase gradient was run from 40% B to 56.5% B in 55 min, 55-67 rain from 56.5% to 51.5%, 67-80 min from 51.5% to 70%, 80-170 min at 70%. The elution was carried out at a flow rate of 1.0 mL/min at the column temperature of 35 ~C with the UV detection wavelength at 256 am. Magnaldehyde B, magnaldehyde E and 8＇,9＇-dihydroxyhonokiol showed good linear relationships with peak areas in the range of 0.00864 to 0.07776 mg/mL, 0.01488 to 0.13392 mg/mL and 0.01568 to 0.10976 mg/mL, respectively. Their corresponding average recoveries were 100.30%, 99.63% and 98.29%, respectively. Our results showed that the established method is simple, rapid, and accurate with good reproducibility for evaluating the quality of raw Chinese medicinal material honokiol. Moreover, another five phenolic compounds, namely erythro-7-O-methylhonoldtriol （1）, threo-7-O-methylhonokitriol （2）, 7-O-ethylhonokitriol （3）, magnaldehyde C （5）, honokiol （8）, together with compounds 4, 6 and 7, were isolated and purified from the remaining substance in the process of preparing the raw material honokiol by silica gel column and semi-preparative HPLC. Their structures were characterized by ID and 2D NMR spectroscopy. Among them, compounds 1 and 2 were reported to have common planar structures and their relative configurations were identified for the first time. Compounds 3 and 7 were not only obtained from the raw medicinal material for the first time but also novel compounds.展开更多
Xu Cuihong, Shu Zhiming, Wang Yan, Miao Fang, Zhou ke. The accumulation rule of the main medicinal components in different organs of Salvia miltiorrhiza Bunge. and Salvia miltiorrhiza Bunge. f. alba. Lishizhen Medicin...Xu Cuihong, Shu Zhiming, Wang Yan, Miao Fang, Zhou ke. The accumulation rule of the main medicinal components in different organs of Salvia miltiorrhiza Bunge. and Salvia miltiorrhiza Bunge. f. alba. Lishizhen Medicine and Materia Medica Research, 2010, 21（09）： 2129-2132. Email： miaofangmf@ 163,com展开更多
The transmission of Ben Cao Gang Mu(《本草纲目》The Grand Compendium of Materia Medica)to Japan in the early 17th century significantly influenced the development of Japanese herbalism.Inspired by materia medica illus...The transmission of Ben Cao Gang Mu(《本草纲目》The Grand Compendium of Materia Medica)to Japan in the early 17th century significantly influenced the development of Japanese herbalism.Inspired by materia medica illustrations in this work,herbalists during the Edo period(1603-1867)recognized the importance of images in herbal literature and created a series of illustrated texts.In the early Edo,materia medica illustrations primarily imitated or referenced Chinese illustrations.Singular picturing techniques,a lack of accuracy,and a reliance on limited object references characterized these works.However,starting in the 18th century,with the support and promotion of the Edo Shogunate,herbalists,naturalists,and illustrators conducted field surveys and picturings of natural products in Japan and neighboring nations.This effort led to a trend of picturing based on nature.As a result,the illustrations in herbal literature from the mid-Edo period began to exhibit a distinct realistic painting style.This development became essential for verifying names and realities in Japanese herbal studies.Furthermore,the knowledge of botany and natural history during this time influenced the creation of herbal illustrations,paving the way for the differentiation of Japanese herbalism in the later Edo period.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.展开更多
Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developme...Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.展开更多
基金Supported by Project of Guizhou Provincial Modernization of Chinese Medicine Material Project(QKHYZ[2011]5049Organization Department of CPCGuizhou Committee(TZJF-2009-02)Promotion Project of Key Scientific and Technological Achievements of Guiyang City([2010]1-T-4)~~
文摘[ Objective ] The paper was to study the effect of controlled atmosphere stress of carbon dioxide （ CO2 ） on Superoxide dismutase （SOD） activity of in- sect, so as to analyze the biological mechanism of the action of controlled atmosphere stress on insect. [ Method] Using nitrotetrazolium blue chloride （NBT） light reduction method, SOD activity of drugstore beetle （ Stegobium panlceum ）, cigarette beetle （ Lasioderma serricorne） and coffee bean beetle （Araecerus fasciculatus） was studied, and the stress response of the enzyme under controlled atmosphere stress of CO2 was analyzed. [ Result ] SOD activity of drugstore beetle, cigarette beetle and coffee bean beetle exposed to controlled atmosphere stress of high concentrations of CO2 for 3 and 6 h had certain degree of increase, and the activity sig- nificantly increased from 2.011±0.954,2.664±0.218 and 1.458±0.718 to 3. 135±0. 105,3.050±0.673 and 2.975±0.229 U/（per pest · 30 min） after treat- ment for 6 h. [ Conclusion] Controlled atmosphere stress of high concentrations of CO2 had certain activation effect on SOD activity of storage pest in Chinese me- dicinal material within the context of sub-lethal events. The results could enrich the insecticidal mechanism of controlled atmosphere and theoretical system of analy- sis on insect resistance to controlled atmosphere.
文摘First of all,this paper introduces the concept,traditional and modern evaluation and conditions of genuine medicinal materials.It focuses on the current situation of genuine medicinal materials in Xinjiang,and suggests that we should strengthen the development,utilization and protection of genuine medicinal resources in Xinjiang from a professional point of view.
文摘In recent years,the price of traditional Chinese medicinal materials soars continuously,and the resulting price risk increasingly looms large,which has critically affected midstream and downstream industries and peoples' demand for drug,and imperiled healthy and orderly development of traditional Chinese medicinal industries.Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present,we winkle out the root cause of soaring price as follows:the supply and demand lose balance;the production costs hike up;there are other factors responsible for soaring price.This paper further analyses the impact of sharp increase in price of traditional Chinese medicinal materials on all links of industry chain as follows:the medicinal herb growers never benefit from soaring price;the counterfeiters and forgers in midstream industry increase;the gross profit rate of Chinese medicine enterprises declines.In accordance with the risk arising from abnormal fluctuation in price of traditional Chinese medicinal materials,corresponding precautionary measures are put forward as follows:promote the quality of traditional Chinese medicinal materials through management of value chain;curtail the production and management cost of traditional Chinese medicinal materials through management of organization chain;stabilize price of traditional Chinese medicinal materials through management of information chain;reduce transaction cost of traditional Chinese medicinal materials through management of logistics chain.
基金Science and Technology Project for the Construction of Chengde National Sustainable Development Agenda Innovation Demonstration Zone(202007F004)Science and Technology Business Project of Hebei Provincial Department of Science and Technology(V1623138472760)。
文摘The paper summarized the effects of soil on the quality of Chinese medicinal materials from the aspects of physical,chemical and biological properties of soil,in order to provide a reference for further research on the internal relationship between soil factors and the quality of Chinese medicinal materials,and to provide a theoretical basis for the cultivation and quality improvement of Chinese medicinal materials.
文摘Through the analysis on the cultivation advantages and development problems of traditional Chinese medicinal planting industry in Shiyan City, Hubei Province, some measures were proposed to enlarge and enhance the traditional Chinese medicinal planting industry, namely, large-scale, standardized, market-oriented and regionalized planting, thereby making it the pillar industry for farmers to increase income.
基金This work was supported by the Integrated Chinese and Western Medicine Key Research Project of the Health Commission of Hubei Province(No.6,2017)the Key Research&Development Project of the Department of Science and Technology of Hubei(No.2020BCB006),China.
文摘Breast cancer is globally the most common invasive cancer in women and remains one of the leading causes of cancer-related deaths.Surgery,radiotherapy,chemotherapy,immunotherapy,and endocrine therapy are currently the main treatments for this cancer type.However,some breast cancer patients are prone to drug resistance related to chemotherapy or immunotherapy,resulting in limited treatment efficacy.Consequently,traditional Chinese medicinal materials(TCMMs)as natural products have become an attractive source of novel drugs.In this review,we summarized the current knowledge on the active components of animal-derived TCMMs,including Ophiocordyceps sinensis-derived cordycepin,the aqueous and ethanolic extracts of O.sinensis,norcantharidin(NCTD),Chansu,bee venom,deer antlers,Ostrea gigas,and scorpion venom,with reference to marked anti-breast cancer effects due to regulating cell cycle arrest,proliferation,apoptosis,metastasis,and drug resistance.In future studies,the underlying mechanisms for the antitumor effects of these components need to be further investigated by utilizing multi-omics technologies.Furthermore,large-scale clinical trials are necessary to validate the efficacy of bioactive constituents alone or in combination with chemotherapeutic drugs for breast cancer treatment.
基金Fundamental research funds of CACMS(ZZ16-YQ-043).
文摘In order to promote the standardization of production and processing of medicinal materials of animal-derivative,on January 15,2024,the China Association of Chinese Medicine approved and released the group standards(T/CACM 1571.1-2024T/CACM 1571.16-2024).Among them,the“Technical code of practice for production and processing of medicinal materials of animalderivative—General rules”(T/CACM 1571.1-2024)(hereinafter referred to as the“General rules”)serves as the overarching guide for the series of specifications.This article provides a detailed interpretation of the“General rules”in order to facilitate the implementation of“Technical code of practice for production and processing of medicinal materials of animal-derivative”and to advance the standardized production of medicinal materials of animal-derivative.
基金supported by the National Natural Science Foundation of China under Grant Nos.71771034 and 72371049the Science and Technology Program of Jieyang under Grant No.2017xm0410and the Dalian High Level Talents Innovation Support Plan under Grant No.2021RD01.
文摘As the national Chinese medicine market develops,Chinese medicinal materials price index(CMMPI)trend is worthy of attention.Predicting future CMMPI trend plays a significant role in risk prevention,cultivation,and trade for farmers and investors.This study aims to design a high-precision model to predict the future trend of the CMMPI.The model incorporates environmental factors such as weather conditions and air quality that have a greater impact on the growth of Chinese medical plants and the supply of Chinese medicinal materials market.Specifically,we collected multi-source heterogeneous data,including weather data,air quality data,and historical CMMPI data,to construct informative features.Additionally,we proposed a feature selection method based on the genetic algorithm and XGBoost to select features.Finally,we transferred the selected features to the bidirectional GRU deep learning to realize the accurate prediction of the CMMPI trend.We collected 46 CMMPI datasets to test the proposed model.The results show that the proposed model obtained more superior prediction compared to the state-of-the-art methods,and specialized in predicting long-term goal(90 days).Taking the Yunnan and Xizang origin index as examples,the experiment results also show the weather and air quality data can improve the prediction performance,as these factors are known to influence the growth and market supply of Chinese medicinal materials.
基金supported by National Natural Science Foundation of China (No.81560705)Inner Mongolia Natural Science Foundation of China (No.2020LH0800)
文摘Traditional Mongolian medicine(TMM)is an important part of Chinese traditional culture,which plays an important role within the medical system of China.The processing of Mongolian medicinal materials is a pharmaceutical technology,which is the unique characteristics of Mongolian medicine.In this paper,the basic concepts related to the processing of Mongolian medicinal materials were introduced,and its scientific research points were put forward,in order to deeply excavate the connotation of Mongolian pharmacy and further study the processing mechanism of Mongolian medicinal materials,so as to provide important basis for the development of Chinese traditional medicine.The essence of Mongolian medicinal materials processing is to use drugs safely and dialectically to ensure the quality of Mongolian medicinal materials.The scientific research sites of Mongolian medicinal materials processing have two categories:reducing toxicity(increasing)effect and synergistic effect of excipients and processing factors.Because of the not perfect research platform of Mongolian medicinal materials and the weak processing power,the development of research of Mongolian medicinal materials is relatively slow.Therefore,there are many research breakthroughs in the interdisciplinary research on the processing of Mongolian medicinal materials,and it is expected to become a research hotspot.
文摘Objective: To analyze the effect of spectrofluorimetry and highperformance liquid chromatography in the detection of aflatoxin in Chinese medicinal materials. Methods: The content of aflatoxin in Chinese medicinal materials was determined by spectrofluorimetry and high-performance liquid chromatography respectively, and the effects of the two detection methods were compared. Results: The results of sample detection by spectrofluorimetry showed that except for Angelica and Sophora flavescens with "detection dada error", the other 25 kinds of Chinese medicinal materials were positive for aflatoxin, but the types of aflatoxin derivatives could not be distinguished, and the tested content was generally high. The recovery experiment of mixed reference substance based on the concentration levels showed that the recovery rate of aflatoxin was 93.60%-99.70% in the case of high-performance liquid chromatography,and the RSD was 1.83%-6.70%. The sample detection results by high-performance liquid chromatography showed that among the 18 kinds of Chinese medicinal materials,only Radix Peucedani, almond, barley, raw Jianqu and aflatoxin were positive, and the types of aflatoxin derivatives could be accurately differentiated. Conclusion: Compared with spectrofluorimetry, high-performance liquid chromatography is more accurate in the determination of aflatoxin content in Chinese medicinal materials, which can distinguish the types of aflatoxin derivatives.
文摘This paper thoroughly explores the multifaceted factors influencing the efficacy of Chinese medicinals and categorizes them into three main groups:medicinal related factors,patient related factors,and practitioner related factors.Regarding medicinal related factors,the place of origin,growing environment,harvesting time,storage conditions,quality control,dosage form selection,compatibility of medicinals,precise dosing,decoction methods,and administration routes all significantly impact efficacy.The place of origin determines the authenticity of medicinals,the growing environment affects their composition,harvesting time influences potency,improper storage leads to deterioration,quality control forms the foundation of efficacy,dosage forms and compatibility of medicinals affect absorption,dosing and decoction methods require precision,and administration routes should be tailored to individuals.Patient related factors include psychological state,individual differences,background,and disease condition.Psychological state affects treatment compliance,individual differences determine medicine responses,background influences patients’understanding of Chinese medicinals,and disease condition directly reflects efficacy.Practitioner related factors encompass theoretical knowledge,clinical experience,inherited practices,psychological state,and professional ethics.Theoretical knowledge guides medication use,clinical experience enhances efficacy,inherited practices influence prescribing styles,psychological state affects doctor–patient communication,and professional ethics ensure medical quality.These interrelated factors collectively influence the efficacy of Chinese medicinals,emphasizing the need for comprehensive consideration in clinical applications to achieve optimal therapeutic outcomes.
基金Supported by Key Technology R&D Program of Hebei Department of Science and Technology(15272506)Scientific Research Project of Hebei Administration of Traditional Chinese Medicine(2015080,2017105)+1 种基金Chinese Medicinal Material Innovation Team Project of Hebei Agricultural Industry Research System(7000120081)National Key Laboratory of Genuine Regional Drug and Significant Increase or Decrease Project of Central Level Project(2060302)
文摘With sulphur-fumigated Chinese medicinal materials （Fritillaria thunbergii , Isatis #utigotica , Asparagus cochinchinensis and Poria cocos ） as the test materials, sulfur dioxide or sulfite residue was determined by the method in Chinese Pharmacopoeia （2015 edition） and titration-fluorescence spectrometry, respec- tively. The results showed that there were significant differences in measured value between titration-fluorescence spectrometry and phmmacopoeia method. The t result of titration-fluorescence spectrometry was much closer to the actual content of sulfur dioxide in Chinese medicinal materials. Thus, titration-fluo- rescence spectrometry had higher application value
基金Major Projects of National Science and Technology on New Drug Creation and Development(Grant No.2009ZX09102-146)
文摘High-performance liquid chromatography （HPLC） was used to quantify magnaldehyde B （6）, magnaldehyde E （4） and 8＇,9＇-dihydroxyhonokiol （7） simultaneously in the raw Chinese medicinal material honokiol. The separation was performed on a reversed-phase Cl8 column by using a gradient elution with mobile phases of water （A） and methanol （B）. The mobile phase gradient was run from 40% B to 56.5% B in 55 min, 55-67 rain from 56.5% to 51.5%, 67-80 min from 51.5% to 70%, 80-170 min at 70%. The elution was carried out at a flow rate of 1.0 mL/min at the column temperature of 35 ~C with the UV detection wavelength at 256 am. Magnaldehyde B, magnaldehyde E and 8＇,9＇-dihydroxyhonokiol showed good linear relationships with peak areas in the range of 0.00864 to 0.07776 mg/mL, 0.01488 to 0.13392 mg/mL and 0.01568 to 0.10976 mg/mL, respectively. Their corresponding average recoveries were 100.30%, 99.63% and 98.29%, respectively. Our results showed that the established method is simple, rapid, and accurate with good reproducibility for evaluating the quality of raw Chinese medicinal material honokiol. Moreover, another five phenolic compounds, namely erythro-7-O-methylhonoldtriol （1）, threo-7-O-methylhonokitriol （2）, 7-O-ethylhonokitriol （3）, magnaldehyde C （5）, honokiol （8）, together with compounds 4, 6 and 7, were isolated and purified from the remaining substance in the process of preparing the raw material honokiol by silica gel column and semi-preparative HPLC. Their structures were characterized by ID and 2D NMR spectroscopy. Among them, compounds 1 and 2 were reported to have common planar structures and their relative configurations were identified for the first time. Compounds 3 and 7 were not only obtained from the raw medicinal material for the first time but also novel compounds.
文摘Xu Cuihong, Shu Zhiming, Wang Yan, Miao Fang, Zhou ke. The accumulation rule of the main medicinal components in different organs of Salvia miltiorrhiza Bunge. and Salvia miltiorrhiza Bunge. f. alba. Lishizhen Medicine and Materia Medica Research, 2010, 21（09）： 2129-2132. Email： miaofangmf@ 163,com
基金financed by the grant from the National Social Science Fund General Project(No.24BZS117).
文摘The transmission of Ben Cao Gang Mu(《本草纲目》The Grand Compendium of Materia Medica)to Japan in the early 17th century significantly influenced the development of Japanese herbalism.Inspired by materia medica illustrations in this work,herbalists during the Edo period(1603-1867)recognized the importance of images in herbal literature and created a series of illustrated texts.In the early Edo,materia medica illustrations primarily imitated or referenced Chinese illustrations.Singular picturing techniques,a lack of accuracy,and a reliance on limited object references characterized these works.However,starting in the 18th century,with the support and promotion of the Edo Shogunate,herbalists,naturalists,and illustrators conducted field surveys and picturings of natural products in Japan and neighboring nations.This effort led to a trend of picturing based on nature.As a result,the illustrations in herbal literature from the mid-Edo period began to exhibit a distinct realistic painting style.This development became essential for verifying names and realities in Japanese herbal studies.Furthermore,the knowledge of botany and natural history during this time influenced the creation of herbal illustrations,paving the way for the differentiation of Japanese herbalism in the later Edo period.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
文摘Editorial Policy Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.It has columns for monographs,reviews,full research articles,short articles,newsletters and clinical case reports of traditional Chinese medicines.
文摘Editorial Policy.Asian Journal of Traditional Medicines is an international journal devoted to the advancement of research on traditional medicines.The followed areas are covered:scientific and technological developments and research achievements in the fields of traditional medicine resources,medicinal material processing,pharmacognosy,natural medicinal chemistry,quality control,pharmacology,pharmacy,and clinical efficacy.
