The present work focused on developing an innovative composite material by reinforcing polymer matrix with highly porous activated charcoal. Polyvinyl alcohol-activated charcoal(PVA-AC) composite scaffolds were deve...The present work focused on developing an innovative composite material by reinforcing polymer matrix with highly porous activated charcoal. Polyvinyl alcohol-activated charcoal(PVA-AC) composite scaffolds were developed by varying the AC concentrations(0, 0.5, 1, 1.5, 2 and 2.5 wt%) in PVA matrix by freeze drying method. The developed scaffolds were characterized for their physicochemical, mechanical and in-vitro biological properties. In addition, the effect of AC on the attachment, proliferation and differentiation of osteoblast MG 63 cells was evaluated by scanning electron microscopy(SEM), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay, alkaline phosphatase(ALP) activity assay and alizarin red stain-based(ARS) assay. All the PVA-AC composite scaffolds exhibited good bioactivity, hemocompatibility and protein adsorption properties. The scaffolds with high AC concentration(2.5 wt%) showed controlled drug release kinetics that are suitable for long term healing. The mechanical properties of all the PVA-AC composite scaffolds were improved when compared to the pure PVA scaffold. The high porosity, swelling degree and hydrophilicity of PVA-AC composite scaffolds facilitated cell attachment and proliferation. This is due to porous AC present in the sample that supported the osteoblast differentiation and formed mineralized nodules without the addition of any extra agents. From the above studies, it can be concluded that PVA-AC composite scaffolds are promising biomaterials for bone tissue engineering applications.展开更多
An organic nonlinear optical material 2-Amino-4-methylpyridinium 2-chloro 4-nitro benzoate (AMPCNB) was synthesized and large size single crystals were grown by slow evaporation solution growth method. Single crystal ...An organic nonlinear optical material 2-Amino-4-methylpyridinium 2-chloro 4-nitro benzoate (AMPCNB) was synthesized and large size single crystals were grown by slow evaporation solution growth method. Single crystal X-ray diffraction study showed that the title compound belongs to monoclinic crystal system with P2<sub>1</sub>/n space group. A powder XRD study was performed to ascertain its phase. The UV–VIS-NIR study was performed to investigate the transparency window and lower cutoff wavelength of the compound, no absorption has been observed between 318 and 1100 nm. The third harmonic efficiency of the title compound has been studied using the Z-scan technique using continuous-wave Nd:YAG laser to confirm its saturable absorption and self-defocusing effect. The photo conducting and charge transport properties are analyzed using photoconductivity and dielectric measurements. Theoretical calculation of molecular polarizability, which is helpful in device fabrication, was carried out from Penn gap, Clausius-Mosotti equations and the obtained results were compared. Mechanical properties of the grown crystal were investigated by Vicker’s microhardness study.展开更多
The control mechanism of mechanical bone remodeling at cellular level was investigated by means of an extensive parametric study on a theoretical model described in this paper. From a perspective of control mechanism,...The control mechanism of mechanical bone remodeling at cellular level was investigated by means of an extensive parametric study on a theoretical model described in this paper. From a perspective of control mechanism, it was found that there are several control mechanisms working simultaneously in bone remodeling which is a complex process. Typically, an extensive parametric study was carried out for investigating model parameter space related to cell differentiation and apoptosis which can describe the fundamental cell lineage behaviors. After analyzing all the combinations of 728 permutations in six model parameters, we have identified a small number of parameter combinations that can lead to physiologically realistic responses which are similar to theoretically idealized physiological responses. The results presented in the work enhanced our understanding on mechanical bone remodeling and the identified control mechanisms can help researchers to develop combined pharmacological-mechanical therapies to treat bone loss diseases such as osteoporosis.展开更多
Nanocrystalline E and η electron compounds and supersaturated solid solution of the Cu-Sn system have been prepared by mechanical alloying of elemental Cu and Sn powders. The atomie alloying and microstructure of the...Nanocrystalline E and η electron compounds and supersaturated solid solution of the Cu-Sn system have been prepared by mechanical alloying of elemental Cu and Sn powders. The atomie alloying and microstructure of the resultant alloys have been investigated by XRD, DSC and 119Sn Mossbauer spectroscopy. A little amount of SnO2 was detected by Mossbauer spectroscopy, although no trace of diffiaction peaks occurred in the XRD pattern. Thus the spectra for all the milled samples should be fitted using two quadrupole-splitting doublets: one corre sponding to SnO2, the other corresponding to the resultant alloys. The composition dependence of the hyperfine parameters has been eXtensively discussed and explained well with respect to oxidation, sudece effect resulting from grain refinement, coordination environment asymmetry and distortion caused or/and induced by mechanical alloying.展开更多
The key problem to the calculation and optimization design of the helicopter 'Ground Resonance' is to correctly build up a mechanical model. In the past, the literature was only concerned with the lag modes of...The key problem to the calculation and optimization design of the helicopter 'Ground Resonance' is to correctly build up a mechanical model. In the past, the literature was only concerned with the lag modes of the rotor blade and the flap modes were neglected. But such approaches should be reconsidered now. In order to study the influences of rotating multiblades rotor on the degrees of freedom and also the flap ''Ground Resonance' of a helicopter, it is necessary to consider not only the lag degrees of freedom but also the flap degrees of freedom. Using Lagrangian equation a dynamical equation of the space model for helicopter 'Ground Resonance'is deduced for the first time. Some computation results show that the mechanical model including both lag DOF and flap DOF is more reasonable.展开更多
The mechanical properties and intrinsic hardness of the α-Ga boron phase (α-Ga-B) are studied by using the combination of first-principles calculations and a semiempirieal macroscopic hardness model. It is found t...The mechanical properties and intrinsic hardness of the α-Ga boron phase (α-Ga-B) are studied by using the combination of first-principles calculations and a semiempirieal macroscopic hardness model. It is found that α- Ga-B is mechanically stable and possesses higher bulk/shear modulus as compared with γ-B28, a newly discovered high-pressure boron phase. The theoretical hardness of α-Ga-B is estimated to be 45 GPa, which is much higher than 38 GPa for γ-B28. The results strongly indicate that α-Ga-B is a potential superhard boron phase. To further obtain insight into the superhard nature of α-Ga-B, we simulate stress-strain curves under tensile and shear deformation. Meanwhile, the microscopic mechanism driving the tensile and shear deformation modes in α-Ga-B is discussed in detail.展开更多
(η^-C_H_5)_2CeCl_5Mg_2(tmed)_2 was used as a catalyst to polymerize isoprene,Terminal ends of polyisoprene were identified as -CH_2-CH=CH_,which indicates that the insertion reaction of the monomer occurred between ...(η^-C_H_5)_2CeCl_5Mg_2(tmed)_2 was used as a catalyst to polymerize isoprene,Terminal ends of polyisoprene were identified as -CH_2-CH=CH_,which indicates that the insertion reaction of the monomer occurred between η^-allyl and cerium ion and gives a direct evidence for the η^-allyl mechanism of conjugated diene polymerzation with rare earth coordination catalysts.展开更多
TPPR and XPS characterizations were combined to study the reaction mechanism of CO2reforming of methane to syngas over Co/γ-Al2O3 catalysts. CH4 shows a tendency to form surface carbons by deep dissociation at high t...TPPR and XPS characterizations were combined to study the reaction mechanism of CO2reforming of methane to syngas over Co/γ-Al2O3 catalysts. CH4 shows a tendency to form surface carbons by deep dissociation at high temperatures. CO2 dissociation reaction also occurs at >673K. It is believed that carbide carbons are active species to generate CO by rcacting with o atoms dissociated from CO2. In the reaction,Co(0) particles are responsible for dissociating CH4 to form active C. abstracting an O atom from CO2 molecule, and transferring O atom to C to form CO.展开更多
The reaction mechanism of ammonia with formaldehyde was investigated by using the intrinsic reaction coordinate(IRC)method on the ab initio RHF/STO-3G basis set. our results indicate that the reaction proceeds in two ...The reaction mechanism of ammonia with formaldehyde was investigated by using the intrinsic reaction coordinate(IRC)method on the ab initio RHF/STO-3G basis set. our results indicate that the reaction proceeds in two stages:the first step yields the molecular complex and the second one is the rearrangement from molecular complex to the reaction proauct.展开更多
It is found that acetoacetanilide possesses very high promoting reactivity towards ceric ion in initiating polymerization of vinyl monomer. The kinetics of acrylamide polymerization and the activation energies were st...It is found that acetoacetanilide possesses very high promoting reactivity towards ceric ion in initiating polymerization of vinyl monomer. The kinetics of acrylamide polymerization and the activation energies were studied. The initiation mechanism of ceric/acetoacetanilide is proposed on the basis of experimental results of FT-IR and ESR.展开更多
Degradation reaction of doxycycline or methacycline was carried out in KOH solution and intense fluorescence was obtained.A degradation mechanism of doxycycline or methacycline was suggested.
The cycloaddition reactions between ketene or substituted ketenes and cyelopentadiene have been studied theoretically by means of the semiempirical AMI method.Three different substituted ketenes have been selected and...The cycloaddition reactions between ketene or substituted ketenes and cyelopentadiene have been studied theoretically by means of the semiempirical AMI method.Three different substituted ketenes have been selected and ten transition states,corresponding to different approach geometries have been located and characterized,The regioselectivity and stereoselectivity of the reactions are correctly predicted by the calculations and the reaction mechanisms are analyzed in terms of electronic and steric effects of the substitutents on the reacting ketene and cyc-lopentadiene.展开更多
The Yellow River has a vast catchment area and historically it is the mother river of the Chinese nation. Now it serves as one of the main theatres for the on-going national campaign to develop China's western... The Yellow River has a vast catchment area and historically it is the mother river of the Chinese nation. Now it serves as one of the main theatres for the on-going national campaign to develop China's western hinterland.……展开更多
Since its founding in 1993, the China Society for Human Rights Studies (CSHRS) has extensively participated inthe human rights work of the United Nations (UN) and has actively carried out international exchange an...Since its founding in 1993, the China Society for Human Rights Studies (CSHRS) has extensively participated inthe human rights work of the United Nations (UN) and has actively carried out international exchange and cooperation. In May 2012, the UN Human Rights Council (UNHRC) initiated the second round of country reviews on human rights.展开更多
IT SMEs as an important force can promote scientific and technological innovation and economic development,the effectiveness of project quality management mechanism is directly related to the survival and development ...IT SMEs as an important force can promote scientific and technological innovation and economic development,the effectiveness of project quality management mechanism is directly related to the survival and development of IT SMEs.This paper take IT SMEs as the research object,which deeply discusses the situation,existing problems and improvement strategies of the project quality management mechanism,and combines agile management and total quality management(TQM)theories to build a dynamic and adaptive project quality management mechanism.Through deeply analysis,the effectiveness of the mechanism is proposed,and the optimization path is proposed,aiming at providing theoretical support and practical guidance for enterprises to improve project delivery quality and enhance market competitiveness.展开更多
Antarctica contains numerous scientific mysteries,and the Antarctic ice sheet and its underlying bedrock contain important information about the geological structure of Antarctica and the evolutionary history of the i...Antarctica contains numerous scientific mysteries,and the Antarctic ice sheet and its underlying bedrock contain important information about the geological structure of Antarctica and the evolutionary history of the ice sheet.In order to obtain the focus of these scientific explorations,the Antarctic drilling engineering is constantly developing.The drilling fluid performance directly determines the success or failure of drilling engineering.In order to enhance the poor performance for drilling fluids due to poor dispersion stability and easy settling of organoclay at ultra-low temperatures,the small-molecule wetting agent(HSR)for drilling fluid suitable for Antarctica was prepared by oleic acid,diethanolamine and benzoic acid as raw materials.Its chemical structure,properties and action mechanism were investigated by various experimental methods.The experimental results showed that 2%HSR could improve the colloidal rate for drilling fluid from 6.4%to 84.8%,and the increase rate of yield point was up to 167%.Meanwhile,it also made the drilling fluid excellent in shear dilution and thixotropy.In addition,2%HSR could increase the density from 0.872 to 0.884 g/cm^(3) at-55 ficial.And the drilling fluid with 2%HSR had a good thermal conductivity of 0.1458 W/(m·K)at-55 ficial.This study gives a new direction for the research of drilling fluid treatment agents suitable for the Antarctic region,which will provide strong support for the scientific exploration of the Antarctic region.展开更多
Urban traffic is a complex system composed of users,drivers,vehicles,roads,the environment,and information and management strategies,characterized by dynamics,randomness,openness,and complexity.Traditional traffic sci...Urban traffic is a complex system composed of users,drivers,vehicles,roads,the environment,and information and management strategies,characterized by dynamics,randomness,openness,and complexity.Traditional traffic science and engineering research usually focuses on specific traffic subsystems[1,2],such as drivers(i.e.,driving behavior),vehicles(i.e.,traffic flow),or traffic control(i.e.,signal systems),and significant progress has been achieved in these areas.展开更多
Irritable bowel syndrome (IBS) is a functional intestinal disease characterized by abdominal pain or discomfort and altered bowel habits. It has drawn great attention because of its high prevalence, reoccurring sympto...Irritable bowel syndrome (IBS) is a functional intestinal disease characterized by abdominal pain or discomfort and altered bowel habits. It has drawn great attention because of its high prevalence, reoccurring symptoms, and severe influence on patients’ lives. Many clinical studies have demonstrated the efficacy of acupuncture-moxibustion in treating IBS. Increasing attention has been paid to research regarding the action mechanisms of acupuncture-moxibustion for IBS, and the adoption of modern techniques has achieved some progress. This article reviews the latest advances among action mechanism studies from the perspectives of gastrointestinal motility, visceral hypersensitivity, the brain-gut axis, the neuroendocrine system, and the immune system. It is shown that acupuncture-moxibustion can effectively regulate the above items, and thus, this treatment should have a high efficacy in the treatment of IBS. This article also identifies existing problems in current mechanism research and raises several ideas for future studies. Further revelations regarding these action mechanisms will promote the application of acupuncture-moxibustion in treating IBS.展开更多
By use of the NCEP/ NCAR reanalysis data, the seasonal variation of the South Asia high (SAH) is analyzed. The influences of temporal and spatial variations of the middle and upper level atmospheric temperatures, the ...By use of the NCEP/ NCAR reanalysis data, the seasonal variation of the South Asia high (SAH) is analyzed. The influences of temporal and spatial variations of the middle and upper level atmospheric temperatures, the visible heat sources, and the diabatic heating rates in the whole atmospheric column on the seasonal variation of the SAH are discussed. Results show that the SAH has two seasonal balancing modes, one of which is the land high in summer and the other the ocean high in winter. The land high itself can be divided into two patterns as well, that is the Tibetan high and the Iranian high. Heating fields have important impacts on the seasonal variation of the SAH. The SAH is a warm high and its center has the property of heat preference, usually locating over or moving to an area with relatively larger heating rates. The annual cycle of the SAH is mainly controlled by the seasonal process of the latent and sensible heating in South Asia. Strong shortwave radiative heating in the north at high latitudes and over the Tibetan Plateau also has an effects on the northward movement and maintenance of the SAH. The cooling effect of infrared radiation is an important cause in weakening the SAH.展开更多
基金the Department of Biotechnology and Medical Engineering, The National Institute of Technology
文摘The present work focused on developing an innovative composite material by reinforcing polymer matrix with highly porous activated charcoal. Polyvinyl alcohol-activated charcoal(PVA-AC) composite scaffolds were developed by varying the AC concentrations(0, 0.5, 1, 1.5, 2 and 2.5 wt%) in PVA matrix by freeze drying method. The developed scaffolds were characterized for their physicochemical, mechanical and in-vitro biological properties. In addition, the effect of AC on the attachment, proliferation and differentiation of osteoblast MG 63 cells was evaluated by scanning electron microscopy(SEM), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay, alkaline phosphatase(ALP) activity assay and alizarin red stain-based(ARS) assay. All the PVA-AC composite scaffolds exhibited good bioactivity, hemocompatibility and protein adsorption properties. The scaffolds with high AC concentration(2.5 wt%) showed controlled drug release kinetics that are suitable for long term healing. The mechanical properties of all the PVA-AC composite scaffolds were improved when compared to the pure PVA scaffold. The high porosity, swelling degree and hydrophilicity of PVA-AC composite scaffolds facilitated cell attachment and proliferation. This is due to porous AC present in the sample that supported the osteoblast differentiation and formed mineralized nodules without the addition of any extra agents. From the above studies, it can be concluded that PVA-AC composite scaffolds are promising biomaterials for bone tissue engineering applications.
文摘An organic nonlinear optical material 2-Amino-4-methylpyridinium 2-chloro 4-nitro benzoate (AMPCNB) was synthesized and large size single crystals were grown by slow evaporation solution growth method. Single crystal X-ray diffraction study showed that the title compound belongs to monoclinic crystal system with P2<sub>1</sub>/n space group. A powder XRD study was performed to ascertain its phase. The UV–VIS-NIR study was performed to investigate the transparency window and lower cutoff wavelength of the compound, no absorption has been observed between 318 and 1100 nm. The third harmonic efficiency of the title compound has been studied using the Z-scan technique using continuous-wave Nd:YAG laser to confirm its saturable absorption and self-defocusing effect. The photo conducting and charge transport properties are analyzed using photoconductivity and dielectric measurements. Theoretical calculation of molecular polarizability, which is helpful in device fabrication, was carried out from Penn gap, Clausius-Mosotti equations and the obtained results were compared. Mechanical properties of the grown crystal were investigated by Vicker’s microhardness study.
文摘The control mechanism of mechanical bone remodeling at cellular level was investigated by means of an extensive parametric study on a theoretical model described in this paper. From a perspective of control mechanism, it was found that there are several control mechanisms working simultaneously in bone remodeling which is a complex process. Typically, an extensive parametric study was carried out for investigating model parameter space related to cell differentiation and apoptosis which can describe the fundamental cell lineage behaviors. After analyzing all the combinations of 728 permutations in six model parameters, we have identified a small number of parameter combinations that can lead to physiologically realistic responses which are similar to theoretically idealized physiological responses. The results presented in the work enhanced our understanding on mechanical bone remodeling and the identified control mechanisms can help researchers to develop combined pharmacological-mechanical therapies to treat bone loss diseases such as osteoporosis.
文摘Nanocrystalline E and η electron compounds and supersaturated solid solution of the Cu-Sn system have been prepared by mechanical alloying of elemental Cu and Sn powders. The atomie alloying and microstructure of the resultant alloys have been investigated by XRD, DSC and 119Sn Mossbauer spectroscopy. A little amount of SnO2 was detected by Mossbauer spectroscopy, although no trace of diffiaction peaks occurred in the XRD pattern. Thus the spectra for all the milled samples should be fitted using two quadrupole-splitting doublets: one corre sponding to SnO2, the other corresponding to the resultant alloys. The composition dependence of the hyperfine parameters has been eXtensively discussed and explained well with respect to oxidation, sudece effect resulting from grain refinement, coordination environment asymmetry and distortion caused or/and induced by mechanical alloying.
文摘The key problem to the calculation and optimization design of the helicopter 'Ground Resonance' is to correctly build up a mechanical model. In the past, the literature was only concerned with the lag modes of the rotor blade and the flap modes were neglected. But such approaches should be reconsidered now. In order to study the influences of rotating multiblades rotor on the degrees of freedom and also the flap ''Ground Resonance' of a helicopter, it is necessary to consider not only the lag degrees of freedom but also the flap degrees of freedom. Using Lagrangian equation a dynamical equation of the space model for helicopter 'Ground Resonance'is deduced for the first time. Some computation results show that the mechanical model including both lag DOF and flap DOF is more reasonable.
基金Supported by the National Natural Science Foundation of China under Grant Nos 21303156,21201148,210303156 and 21403185the Natural Science Foundation of Hebei Province under Grant Nos B2011203121 and B2012203005
文摘The mechanical properties and intrinsic hardness of the α-Ga boron phase (α-Ga-B) are studied by using the combination of first-principles calculations and a semiempirieal macroscopic hardness model. It is found that α- Ga-B is mechanically stable and possesses higher bulk/shear modulus as compared with γ-B28, a newly discovered high-pressure boron phase. The theoretical hardness of α-Ga-B is estimated to be 45 GPa, which is much higher than 38 GPa for γ-B28. The results strongly indicate that α-Ga-B is a potential superhard boron phase. To further obtain insight into the superhard nature of α-Ga-B, we simulate stress-strain curves under tensile and shear deformation. Meanwhile, the microscopic mechanism driving the tensile and shear deformation modes in α-Ga-B is discussed in detail.
文摘(η^-C_H_5)_2CeCl_5Mg_2(tmed)_2 was used as a catalyst to polymerize isoprene,Terminal ends of polyisoprene were identified as -CH_2-CH=CH_,which indicates that the insertion reaction of the monomer occurred between η^-allyl and cerium ion and gives a direct evidence for the η^-allyl mechanism of conjugated diene polymerzation with rare earth coordination catalysts.
文摘TPPR and XPS characterizations were combined to study the reaction mechanism of CO2reforming of methane to syngas over Co/γ-Al2O3 catalysts. CH4 shows a tendency to form surface carbons by deep dissociation at high temperatures. CO2 dissociation reaction also occurs at >673K. It is believed that carbide carbons are active species to generate CO by rcacting with o atoms dissociated from CO2. In the reaction,Co(0) particles are responsible for dissociating CH4 to form active C. abstracting an O atom from CO2 molecule, and transferring O atom to C to form CO.
基金This work was partly supported by the National Science Foundation of China
文摘The reaction mechanism of ammonia with formaldehyde was investigated by using the intrinsic reaction coordinate(IRC)method on the ab initio RHF/STO-3G basis set. our results indicate that the reaction proceeds in two stages:the first step yields the molecular complex and the second one is the rearrangement from molecular complex to the reaction proauct.
文摘It is found that acetoacetanilide possesses very high promoting reactivity towards ceric ion in initiating polymerization of vinyl monomer. The kinetics of acrylamide polymerization and the activation energies were studied. The initiation mechanism of ceric/acetoacetanilide is proposed on the basis of experimental results of FT-IR and ESR.
文摘Degradation reaction of doxycycline or methacycline was carried out in KOH solution and intense fluorescence was obtained.A degradation mechanism of doxycycline or methacycline was suggested.
文摘The cycloaddition reactions between ketene or substituted ketenes and cyelopentadiene have been studied theoretically by means of the semiempirical AMI method.Three different substituted ketenes have been selected and ten transition states,corresponding to different approach geometries have been located and characterized,The regioselectivity and stereoselectivity of the reactions are correctly predicted by the calculations and the reaction mechanisms are analyzed in terms of electronic and steric effects of the substitutents on the reacting ketene and cyc-lopentadiene.
文摘 The Yellow River has a vast catchment area and historically it is the mother river of the Chinese nation. Now it serves as one of the main theatres for the on-going national campaign to develop China's western hinterland.……
文摘Since its founding in 1993, the China Society for Human Rights Studies (CSHRS) has extensively participated inthe human rights work of the United Nations (UN) and has actively carried out international exchange and cooperation. In May 2012, the UN Human Rights Council (UNHRC) initiated the second round of country reviews on human rights.
基金Young and Middle-aged Teachers’Basic Research Ability Improvement Project of Universities in Guangxi 2024Research on Coordinated Development of Smart Tourism and Rural Revitalization in Southwest China(Project No.:24KY0655)。
文摘IT SMEs as an important force can promote scientific and technological innovation and economic development,the effectiveness of project quality management mechanism is directly related to the survival and development of IT SMEs.This paper take IT SMEs as the research object,which deeply discusses the situation,existing problems and improvement strategies of the project quality management mechanism,and combines agile management and total quality management(TQM)theories to build a dynamic and adaptive project quality management mechanism.Through deeply analysis,the effectiveness of the mechanism is proposed,and the optimization path is proposed,aiming at providing theoretical support and practical guidance for enterprises to improve project delivery quality and enhance market competitiveness.
基金financially supported by the National Natural Science Foundation of China(No.52274021)the National Key Research and Development Program of China(No.2021YFA0719102)。
文摘Antarctica contains numerous scientific mysteries,and the Antarctic ice sheet and its underlying bedrock contain important information about the geological structure of Antarctica and the evolutionary history of the ice sheet.In order to obtain the focus of these scientific explorations,the Antarctic drilling engineering is constantly developing.The drilling fluid performance directly determines the success or failure of drilling engineering.In order to enhance the poor performance for drilling fluids due to poor dispersion stability and easy settling of organoclay at ultra-low temperatures,the small-molecule wetting agent(HSR)for drilling fluid suitable for Antarctica was prepared by oleic acid,diethanolamine and benzoic acid as raw materials.Its chemical structure,properties and action mechanism were investigated by various experimental methods.The experimental results showed that 2%HSR could improve the colloidal rate for drilling fluid from 6.4%to 84.8%,and the increase rate of yield point was up to 167%.Meanwhile,it also made the drilling fluid excellent in shear dilution and thixotropy.In addition,2%HSR could increase the density from 0.872 to 0.884 g/cm^(3) at-55 ficial.And the drilling fluid with 2%HSR had a good thermal conductivity of 0.1458 W/(m·K)at-55 ficial.This study gives a new direction for the research of drilling fluid treatment agents suitable for the Antarctic region,which will provide strong support for the scientific exploration of the Antarctic region.
基金partially supported by the National Natural Science Foundation of China(72288101 and 72242102)。
文摘Urban traffic is a complex system composed of users,drivers,vehicles,roads,the environment,and information and management strategies,characterized by dynamics,randomness,openness,and complexity.Traditional traffic science and engineering research usually focuses on specific traffic subsystems[1,2],such as drivers(i.e.,driving behavior),vehicles(i.e.,traffic flow),or traffic control(i.e.,signal systems),and significant progress has been achieved in these areas.
基金Supported by National Natural Science Foundation of China,No.81273843,No.81072879National Key Basic Research Program of China,No.2009CB522900
文摘Irritable bowel syndrome (IBS) is a functional intestinal disease characterized by abdominal pain or discomfort and altered bowel habits. It has drawn great attention because of its high prevalence, reoccurring symptoms, and severe influence on patients’ lives. Many clinical studies have demonstrated the efficacy of acupuncture-moxibustion in treating IBS. Increasing attention has been paid to research regarding the action mechanisms of acupuncture-moxibustion for IBS, and the adoption of modern techniques has achieved some progress. This article reviews the latest advances among action mechanism studies from the perspectives of gastrointestinal motility, visceral hypersensitivity, the brain-gut axis, the neuroendocrine system, and the immune system. It is shown that acupuncture-moxibustion can effectively regulate the above items, and thus, this treatment should have a high efficacy in the treatment of IBS. This article also identifies existing problems in current mechanism research and raises several ideas for future studies. Further revelations regarding these action mechanisms will promote the application of acupuncture-moxibustion in treating IBS.
基金This research was jointly sponsored by "The National Key Programme for Developing Basic Sciences"project (1998040900)Part Ⅰ, and the National Natural Science Foundation of China Project:"Studies on Interaction between the South Asia High and the Asian Monsoon and lts Mechanisms"under Grant No.40175021.
文摘By use of the NCEP/ NCAR reanalysis data, the seasonal variation of the South Asia high (SAH) is analyzed. The influences of temporal and spatial variations of the middle and upper level atmospheric temperatures, the visible heat sources, and the diabatic heating rates in the whole atmospheric column on the seasonal variation of the SAH are discussed. Results show that the SAH has two seasonal balancing modes, one of which is the land high in summer and the other the ocean high in winter. The land high itself can be divided into two patterns as well, that is the Tibetan high and the Iranian high. Heating fields have important impacts on the seasonal variation of the SAH. The SAH is a warm high and its center has the property of heat preference, usually locating over or moving to an area with relatively larger heating rates. The annual cycle of the SAH is mainly controlled by the seasonal process of the latent and sensible heating in South Asia. Strong shortwave radiative heating in the north at high latitudes and over the Tibetan Plateau also has an effects on the northward movement and maintenance of the SAH. The cooling effect of infrared radiation is an important cause in weakening the SAH.