In the present study,nano-sized TiO2 /Al2O3 modified PVDF membranes (MM) were fabricated and utilized for anionic polyacrylamide ( APAM) separation. The results showed that,compared with PVDF membrane (OM) ,the contac...In the present study,nano-sized TiO2 /Al2O3 modified PVDF membranes (MM) were fabricated and utilized for anionic polyacrylamide ( APAM) separation. The results showed that,compared with PVDF membrane (OM) ,the contact angle of MM decreases from 83. 64° to 67. 42°,which indicates the increase of the hydrophilicity of MM. The relative flux (RF) decline curve of this ultrafiltration of APAM in water with time shows an obvious two stage properties. The cake filtration models were used to predict the performance of different time over the complete range of filtration times. All the four cake models could simulate this UF process to a certain extent,and the suitability of the two kinds of membranes was: cake filtration > intermediate pore blocking > standard pore blocking > complete pore blocking models. However,they became more and more unsuited to this process with time extending. Surface and cross-sectional morphology of membrane was investigated by SEM to make an advanced certificate of this UF mechanism.展开更多
The authors regret that in the paper of Baldovino et al.(2019),published in Journal of Rock Mechanics and Geotechnical Engineering(JRMGE),Eq.(2)must be corrected.Eq.(2)in the original paper describes a formula to calc...The authors regret that in the paper of Baldovino et al.(2019),published in Journal of Rock Mechanics and Geotechnical Engineering(JRMGE),Eq.(2)must be corrected.Eq.(2)in the original paper describes a formula to calculate the unconfined compressive strength(q_u).But Authors wrote it as if it were the formula for calculating the split tensile strength(qt).To amend this error,Eq.(1)and Eq.(2)are the correct expressions for q_u and q_t measurements,respectively.展开更多
Objective: to study the efficacy and adverse reactions of carrelizumab combined with siB-IMRT and pemetrexed disodium + cisplatin in the treatment of locally advanced non-squamous non-small cell lung cancer (NSCLC). M...Objective: to study the efficacy and adverse reactions of carrelizumab combined with siB-IMRT and pemetrexed disodium + cisplatin in the treatment of locally advanced non-squamous non-small cell lung cancer (NSCLC). Methods: 120 patients with non-squamous NSCLC were selected and divided into control group and study group, with 60 patients in each group. The control group was only given SIB-IMRT combined with pemetrexed disodium + cisplatin chemotherapy, while the study group was given carrelizumab on the day before chemotherapy on the basis of the control group. Results: the total remission rate in study group was 90.00% (54/60) higher than 76.67% (46/60) in control group (Z=2.682, P<0.05). The PFS and OS of study group were longer than those of control group (t=20.900, P<0.05), and longer than those of control group (t=16.696, P<0.05). After treatment, the expression levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in peripheral blood of patients in the study group were higher than those in the control group (P<0.05). The expression levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in peripheral blood of 2 groups after treatment were higher than before treatment (P<0.05). After treatment, the levels of IL-2, IL-6, IL-10 and TNF-α in peripheral blood of patients in the study group were lower than those in the control group (P<0.05). The levels of IL-2, IL-6, IL-10 and TNF-α in peripheral blood of 2 groups after treatment were lower than before (P<0.05). Conclusions: carrelizumab combined with SIB-IMRT and pemetrexed disodium + cisplatin has significant efficacy in locally advanced non-squamous NSCLC patients, and there is no significant increase in adverse reactions.展开更多
为提高复杂海洋环境中无人机自主降落时分割目标的实时性和精确性,研究主干网络和浅深层特征对分割算法性能的影响问题,基于DeepLabV3+框架建立一种基于主干网络浅深层特征的无人机海上分割(shallow and deep features of backbone,SDFB...为提高复杂海洋环境中无人机自主降落时分割目标的实时性和精确性,研究主干网络和浅深层特征对分割算法性能的影响问题,基于DeepLabV3+框架建立一种基于主干网络浅深层特征的无人机海上分割(shallow and deep features of backbone,SDFB)算法。首先,针对风浪扰动降低目标稳定性的问题,优化MobileNetV2结构提出一种特征提取方法,解决了算法无法处理短时间目标变化较大图像的问题;然后,针对深层特征输出通道数较多且存在不均匀分布大气湍流噪声的问题,利用本地全局信息选择性地聚合特征,提出一种特征筛选机制,剔除冗余通道的同时解决了算法对环境噪声敏感度高的问题;其次,针对光照不匀降低目标边界清晰度问题,从浅层空间维度和深层通道维度中提取轮廓信息建立一种并行轮廓学习机制,解决了算法利用轮廓特征效率低的问题;最后,针对障碍物遮挡破坏目标特征完整性问题,融合优化后的条带池化建立一种特征融合机制,解决了算法无法联系离散分布特征问题。实验表明,SDFB算法的实时性和精确性均高于其他算法,能够更好地适应海上场景无人机分割目标需求。展开更多
In order to speed underwater launch of minor-caliber weapons,a sealing device can be set in front of underwater muzzle to separate water,preventing the muzzle from water immersion.By establishing and simplifying the m...In order to speed underwater launch of minor-caliber weapons,a sealing device can be set in front of underwater muzzle to separate water,preventing the muzzle from water immersion.By establishing and simplifying the model of underwater weapon sealing device and unstructured mesh computing domain model based on computational fluid dynamics（CFD）,dynamic mesh and user defined function（UDF）,the N-S equation is solved and the numerical analysis and calculation of the complex two-phase flow inside the sealing device are carried out.The results show that the gas discharged from the sealing device is conducive to the formation of the projectile supercavity.When the projectile is launched at 5munder water,the shock wave before and after the projectile has impact on the box body up to 100 MPa,therefore the sealing device must be strong enough.The research results have the vital significance to the design of underwater weapon sealing device and the formation of the projectile supercavitation.展开更多
基金Sponsored by the National Natural Science Foundation of China (Grant No.50978068)International Cooperation Program (Grant No.2010DFA92460)+1 种基金National High Technology Research and Development Program of China (863 Program,Grant No.2008AA06Z304)Tianjin Key Laboratory of Aquatic Science and Technology
文摘In the present study,nano-sized TiO2 /Al2O3 modified PVDF membranes (MM) were fabricated and utilized for anionic polyacrylamide ( APAM) separation. The results showed that,compared with PVDF membrane (OM) ,the contact angle of MM decreases from 83. 64° to 67. 42°,which indicates the increase of the hydrophilicity of MM. The relative flux (RF) decline curve of this ultrafiltration of APAM in water with time shows an obvious two stage properties. The cake filtration models were used to predict the performance of different time over the complete range of filtration times. All the four cake models could simulate this UF process to a certain extent,and the suitability of the two kinds of membranes was: cake filtration > intermediate pore blocking > standard pore blocking > complete pore blocking models. However,they became more and more unsuited to this process with time extending. Surface and cross-sectional morphology of membrane was investigated by SEM to make an advanced certificate of this UF mechanism.
文摘The authors regret that in the paper of Baldovino et al.(2019),published in Journal of Rock Mechanics and Geotechnical Engineering(JRMGE),Eq.(2)must be corrected.Eq.(2)in the original paper describes a formula to calculate the unconfined compressive strength(q_u).But Authors wrote it as if it were the formula for calculating the split tensile strength(qt).To amend this error,Eq.(1)and Eq.(2)are the correct expressions for q_u and q_t measurements,respectively.
文摘Objective: to study the efficacy and adverse reactions of carrelizumab combined with siB-IMRT and pemetrexed disodium + cisplatin in the treatment of locally advanced non-squamous non-small cell lung cancer (NSCLC). Methods: 120 patients with non-squamous NSCLC were selected and divided into control group and study group, with 60 patients in each group. The control group was only given SIB-IMRT combined with pemetrexed disodium + cisplatin chemotherapy, while the study group was given carrelizumab on the day before chemotherapy on the basis of the control group. Results: the total remission rate in study group was 90.00% (54/60) higher than 76.67% (46/60) in control group (Z=2.682, P<0.05). The PFS and OS of study group were longer than those of control group (t=20.900, P<0.05), and longer than those of control group (t=16.696, P<0.05). After treatment, the expression levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in peripheral blood of patients in the study group were higher than those in the control group (P<0.05). The expression levels of CD3+, CD4+, CD8+ and CD4+/CD8+ in peripheral blood of 2 groups after treatment were higher than before treatment (P<0.05). After treatment, the levels of IL-2, IL-6, IL-10 and TNF-α in peripheral blood of patients in the study group were lower than those in the control group (P<0.05). The levels of IL-2, IL-6, IL-10 and TNF-α in peripheral blood of 2 groups after treatment were lower than before (P<0.05). Conclusions: carrelizumab combined with SIB-IMRT and pemetrexed disodium + cisplatin has significant efficacy in locally advanced non-squamous NSCLC patients, and there is no significant increase in adverse reactions.
文摘为提高复杂海洋环境中无人机自主降落时分割目标的实时性和精确性,研究主干网络和浅深层特征对分割算法性能的影响问题,基于DeepLabV3+框架建立一种基于主干网络浅深层特征的无人机海上分割(shallow and deep features of backbone,SDFB)算法。首先,针对风浪扰动降低目标稳定性的问题,优化MobileNetV2结构提出一种特征提取方法,解决了算法无法处理短时间目标变化较大图像的问题;然后,针对深层特征输出通道数较多且存在不均匀分布大气湍流噪声的问题,利用本地全局信息选择性地聚合特征,提出一种特征筛选机制,剔除冗余通道的同时解决了算法对环境噪声敏感度高的问题;其次,针对光照不匀降低目标边界清晰度问题,从浅层空间维度和深层通道维度中提取轮廓信息建立一种并行轮廓学习机制,解决了算法利用轮廓特征效率低的问题;最后,针对障碍物遮挡破坏目标特征完整性问题,融合优化后的条带池化建立一种特征融合机制,解决了算法无法联系离散分布特征问题。实验表明,SDFB算法的实时性和精确性均高于其他算法,能够更好地适应海上场景无人机分割目标需求。
基金National Natural Science Foundation of China(No.51175481)
文摘In order to speed underwater launch of minor-caliber weapons,a sealing device can be set in front of underwater muzzle to separate water,preventing the muzzle from water immersion.By establishing and simplifying the model of underwater weapon sealing device and unstructured mesh computing domain model based on computational fluid dynamics（CFD）,dynamic mesh and user defined function（UDF）,the N-S equation is solved and the numerical analysis and calculation of the complex two-phase flow inside the sealing device are carried out.The results show that the gas discharged from the sealing device is conducive to the formation of the projectile supercavity.When the projectile is launched at 5munder water,the shock wave before and after the projectile has impact on the box body up to 100 MPa,therefore the sealing device must be strong enough.The research results have the vital significance to the design of underwater weapon sealing device and the formation of the projectile supercavitation.
