<strong>Introduction: </strong>Tracheotomy is a commonly performed procedure, but with very large disparities according to the teams, both in terms of frequency and modality (percutaneous or surgical), tra...<strong>Introduction: </strong>Tracheotomy is a commonly performed procedure, but with very large disparities according to the teams, both in terms of frequency and modality (percutaneous or surgical), tracheotomy has been evolved with medical advances. The objective of this study was to clarify the indications and complications of emergency tracheotomies at the National hospital center (CHN) in Nouakchott Mauritania. <strong>Materials and Methods: </strong>It is a retrospective study of tracheotomies performed in the ENT department of the CHN during the period from January 1, 2010 to December 31, 2018. The indications and complications were noted, as well as the modalities and time of decannulation. <strong>Results:</strong> Tracheotomy was motivated by upper airway obstruction (UAO) in 139 (94%) cases (mean age 32.5 years), or the need for prolonged ventilation in 8 patients (median age 46 years). Sixteen (7%) early complications were noted with 5 untimely decannulations including one fatal and 5 obstructive plug responsible for another death. Six pneumothorax was observed. Fifteen (26%) late complications required additional surgery;7% (n = 11) of patients were decannulated with a mean duration of tracheotomy 26 months. In 19 (28%) cases of decannulations, the persistence of a tracheocutaneous fistula required surgery. <strong>Conclusion:</strong> Emergency tracheotomy is a survival gesture that is sure to be effective. A tracheotomy is not deprived of complications. Familiarity with the technique, the right choice of equipment, perfect knowledge of the anatomical relationships of the trachea, rigorous monitoring and postoperative care represent the main conditions for minimizing the risk of complications.展开更多
Trauma care including abdominal trauma is a big challenge. It is associated with high morbidity and mortality and continues to be a public health problem worldwide. The main aims of our study were to assess the patter...Trauma care including abdominal trauma is a big challenge. It is associated with high morbidity and mortality and continues to be a public health problem worldwide. The main aims of our study were to assess the patterns and outcomes of our patients, and to describe our experience in management of abdominal trauma. This descriptive retrospective study was conducted in general surgery department at National Centre Hospital of Nouakchott in Mauritania. We recruited patients presented at our department with abdominal trauma (2012-2016). Out of 100 cases, 92% were men. Mean age: 22.78 years (5 - 70 years). Eighty percent of patients suffered of penetrating abdominal trauma. Stab injuries were the most frequent mechanism (60%). The commonest organ injury was small intestine (16%). Mortality has been strongly related to road traffic accidents. Cares of severe abdominal traumas are not common in our hospital, due to lack of required overall data. Emergency health system is needed to better care of trauma patients in Mauritania.展开更多
<strong>Introduction:</strong> Primary open angle glaucoma (POAG) is an anterior optic neuropathy of chronic and progressive course, characterized by perimeter alteration and excavation of the specific opt...<strong>Introduction:</strong> Primary open angle glaucoma (POAG) is an anterior optic neuropathy of chronic and progressive course, characterized by perimeter alteration and excavation of the specific optic disc. This neuropathy is usually accompanied by ocular hypertonia. The iridocorneal angle remains open in gonioscopy. POAG is the primary cause of irreversible blindness in adults around the world, posing a real public health and quality of life problem as well as an economic problem. The progressive and irreversible loss of vision makes POAG a disease that can lead to blindness. The main objective of our study is to describe the epidemiological, clinical and therapeutic aspects of primary open angle glaucoma in the ophthalmology department of the National Hospital Center of Nouakchott. <strong>Materials and Methods:</strong> It was a prospective descriptive study of 6 months (March 1<sup>st</sup> 2017 to August 30<sup>th</sup> 2017), on patients with a POAG with the presence of at least one of the three signs (intraocular pressure > 21 mmHg, papillary cup/disc vertical excavation ≥ 0.5 and a field altered apart from all other causes). All glaucoma patients seen during the study period benefited from a complete eye examination. The studied variables were the family history of glaucoma, age, intra ocular pressure (IOP) and pachymeter. <strong>Results:</strong> The mean age was 58.7 years. About 2/3 of the patients had a lower pachymeter to normal (63% of cases), a genetically thinner cornea results in an underestimation of the IOP measurement. The male was the most represented with a sex ratio M/F (1.42), the main characteristic factors were family history of glaucoma (39.7%), artery hypertension, diabetic and headache. The success rate of surgery was 69.8%, while 11% of our patients had refused any kind of treatment, no complications were noted, <strong>Conclusion:</strong> POAG is a multifactorial condition which can lead to blindness if not early diagnosed or if treatment is poorly conducted, hence the importance of prevention by screening and informing the population about this pathology.展开更多
<strong>Introduction:</strong> Transurethral resection of the prostate (TURP), entered our service in October 2015, since then it became a part of the service daily activity. The aim of our study is to ass...<strong>Introduction:</strong> Transurethral resection of the prostate (TURP), entered our service in October 2015, since then it became a part of the service daily activity. The aim of our study is to assess the acceptance of the technic by our patients and by the nursing staff and to analyze the results of our initial experience. <strong>Materials and Methods:</strong> Retrospective study over 14-month (October 2015 to December 2016);bringing together all the patients who received TURP. The inclusion criteria are to have benefited from a TURP in our service. The exclusion criteria all patients operated by other techniques. It was a monopolar resection of the prostate using a glycocolle loop, the size limit of the prostate was 65 cc or less. A questionnaire on the knowledge of the technique and its acceptance is made. The parameters studied the age of the patient;surgical indications;the course of the operation, the complications and the course. The frequency of TURP compared to other techniques and the demand for this technique by patients. The urinary catheter was left in place for 4 days, the patients were seen again on day 7 after the catheter was removed to assess the urine flow, a question regarding the opinion of the nursing staff was included and analyzed separately. <strong>Results:</strong> The total number of patients was 146;the mean age was 68.2 years. The main cause of consultation was urine retention 65%. The average duration of the intervention was 56 minutes. The average length of hospital stay was 28 hours. The urinary catheter was removed on day 4. Complications were bleeding in 7% of cases requiring blood transfusions. Failure to remove the indwelling catheter leads to revision via the transurethral route. The TURP syndrome was observed in 2 patients in our early patients but quickly resolved. The outcome was favorable in 75% of cases. Post operating management give satisfaction for nurse and acceptance was a success. <strong>Conclusion:</strong> TURP is now a routine surgical activity;it seems to have an upright place for BPH in our department;its impact on morbidity was remarkable.展开更多
Most countries’ land use and land cover (LULC) are changing dramatically today. Most of these changes are related to the way humans and the environment interact. Various methodologies and data sources have been used ...Most countries’ land use and land cover (LULC) are changing dramatically today. Most of these changes are related to the way humans and the environment interact. Various methodologies and data sources have been used in conjunction with remote sensing (RS) to categorize and map changes in LULC. This study used RS and Geographic Information System (GIS) tools to analyze LULC change and transitions from 1984 to 2022 in a tropical forested landscape in southwest Mauritania. Using a suitable and high-quality collection of Landsat satellite images. For the classification and creation of LULC maps for the selected periods, the supervised technique using a maximum likelihood classifier was used. The results indicated that there was a remarkable change in all classes of LULC, with an increase in all classes, except barren land, which had a tremendous decrease of −68.58% for the total study area. Therefore, for the total study area, an increase in agricultural land (221%), water bodies (118.46%), vegetation (57.50%), and built-up areas (14.65%) was observed. We believe that by informing policymakers, environmental managers, and the general public about the current changes, our study will help the region to establish appropriate land use rules that may lead to policy document development.展开更多
Introduction: since its creation, our urology department has taken care of tumor pathologies in particular kidney cancer in adults;our goal is to study the clinical and therapeutic epidemiological profiles of adult ki...Introduction: since its creation, our urology department has taken care of tumor pathologies in particular kidney cancer in adults;our goal is to study the clinical and therapeutic epidemiological profiles of adult kidney cancer in Mauritania. Materials and Methods: We carried out a retrospective study over a period of six years, from January 1, 2012 to December 31, 2017, including all cases of adult kidney cancer registered in the urology-andrology departments of the Cheikh Zayed Hospital and Pathological Anatomy of the National Hospital of Nouakchott (Mauritania). Results: we collected 50 cases of kidney cancer. The average annual incidence was 8.3 cases. The average age of the patients was 52.98 years with extremes of 18 and 84 years. There was a female predominance (52%) or 29 women for 21 men. Lumbar pain was the most frequent clinical expression, more than half of the patients had symptoms over a period of at least 12 months before the first consultation. The left kidney was the most frequently affected. The right localization was demonstrated in 23 patients, the extension assessment was made with thoraco-abdomino-pelvic CT in 40 patients. Twelve patients had a tumor localized in the kidney. The extension assessment had made it possible to objectify the existence of metastases in 17 of our patients (37%). The preferred locations of these metastases were pulmonary and hepatic. Surgical intervention was performed in 44 patients (88%), of whom 36 underwent radical nephrectomy (72%), and two patients underwent partial nephrectomy (4.5%). Surgical abstention was decided from the outset in 6 patients (13.6%). None of our patients had received treatment with anti-angiogenics. The histological type most observed in our patients was renal cell carcinoma, observed in 34 patients, or 77.72%. At the time of the study, more than a third of the patients had died. The mortality rate in our series had reached 24%. A specific survival rate could not be assessed due to lack of information in the files and significant numbers of patients lost to follow-up at the time of the study. Conclusion: adult kidney cancer in Mauritania is characterized by its low incidence, its occurrence in a relatively young population, its female predominance, its often late diagnosis at locally advanced and metastatic stages, and the treatment is the most often surgical.展开更多
The aim of our study was to determine epidemiological, clinical and therapeutic profile of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in No...The aim of our study was to determine epidemiological, clinical and therapeutic profile of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania. All cases of colorectal cancers histologically confirmed were included. The Astler and Coller classification was used to classify lesions by level of extension. Results: 225 patients were included with a sex ratio (M/F) of 1.39, an average age of 52.3 years. Location of the lesion was rectal (37.7%) and colonic (62.3%). Clinical manifestations were dominated by rectal bleeding (26.9%), occlusive syndrome (16.5%) and transit disorders (11.6%). Endoscopic lesions were of stenosing (45.2%), ulcero-burgeoning (39%), ulcerous (7.5%) and burgeoning (4.7%) types. Histological profiles were adenocarcinoma (88.9%), carcinoma (3.1%) and lymphoma (2.6%). The work-up for extension revealed metastasis in 33.6% of cases. These were stage B (49%) and C (36%) among the 95 cancers that received the Astler and Coller classification. The treatment was curative (80.83%) and palliative (19.16%). Conclusion: Colorectal cancer is a reality in Africa. However, its diagnosis still remains delayed, which increases the prognosis, hence the need to promote screening tests.展开更多
In this study,the effects of chemical refining on the physicochemical indices,environmental pollutants,lipid functional groups,relaxation characteristics,fatty acid profiles,and triglyceride(TG)molecular species in cr...In this study,the effects of chemical refining on the physicochemical indices,environmental pollutants,lipid functional groups,relaxation characteristics,fatty acid profiles,and triglyceride(TG)molecular species in crude oil extracted from small fish in Mauritania were evaluated.The acid,peroxide,and iodine values of crude oil were identified as 5.52 mg KOH/g,1.73 meq/kg,and 200.78 g/100 g oil,respectively.After refining,these values were determined to be 0.29 mg KOH/g,0.76 meq/kg,and 210.80 g/100 g oil,respectively.The polychlorinated biphenyls and arsenic content of crude oil were identified as 32.30μg/kg and 1.00 mg/kg,respectively.After refining,these were not detected.The content of eicosapentaenoic acid(EPA)and docosahexaenoic acid(DHA)accounted for as much as 87.55%of the polyunsaturated fatty acids in the refined oil,indicating that high-quality fish oil is suitable as a food supplement.The correlation coefficient of the infrared spectra before and after refining was 0.968,and the relaxation time and peak shape data were almost similar before and after purification.Meanwhile,there were no significant differences(P≥0.05)in fatty acid profiles between the crude and refined oils,except for C16:0(P<0.01).Based on UPLC-Q E-MS/MS detection,137 TG molecules were identified in both crude and refined oils.Among the detected TG molecular species,64 contained EPA or DHA,which accounted for 46.83%and 46.00%of the total TG content in crude and refined oils,respectively.After refining,the content of the molecular species decreased by 31.95 mg/10 g,among which the three most variable molecular species were TG(16:0/18:1/22:6),(16:1/16:2/18:1),and(18:4/16:0/20:5),accounting for 29.26%of the decline of the molecular species.Overall,the refining process had little effect on the fatty acid profile and distribution of TG molecular species in fish oil.展开更多
Background:Among parasitic infections,schistosomiasis ranks second after malaria in terms of worldwide morbidity.Despite efforts to contain transmission,more than 230 million people are infected,of which 85%live in Su...Background:Among parasitic infections,schistosomiasis ranks second after malaria in terms of worldwide morbidity.Despite efforts to contain transmission,more than 230 million people are infected,of which 85%live in Sub-Saharan Africa.While the epidemiologic characteristics of schistosomiasis have been extensively studied across endemic settings,social factors have been paid less attention.The current study assesses community knowledge of schistosomiasis causes,transmission,signs,symptoms and prevention,as well as healthcare-seeking behaviours in two West African settings,with the aim of strengthening schistosomiasis control interventions.Methods:From August 2014 to June 2015,we conducted two cross-sectional surveys in Korhogo,Cote d’Ivoire and Kaedi,Mauritania.We applied a questionnaire to collect quantitative data at the household level in Korhogo(n=1456)and Kaedi(n=1453).Focus group discussions(Korhogo:n=32,Kaedi:n=32)and participatory photography(photovoice)(Korhogo:n=16,Kaedi:n=16)were conducted within the communities to gather qualitative data.In addition,semi-structured interviews were used to discuss with key informants from control programmes,nongovernmental organizations and health districts(Korhogo:n=8,Kaedi:n=7).Results:The study demonstrated that schistosomiasis is not well known by the communities;64.1%claimed to know the causes of the disease,but the reality is different.This knowledge is more from cultural than biomedical source.It was observed that social construction of the disease is different from the biomedical definition.In Korhogo,schistosomiasis was often associated with several other diseases,notably stomach ulcer and gonorrhoea.The populations believe that schistosomiasis is caused by exposure to goat or dog urine in the environment.In Kaedi,schistosomiasis is considered as a disease transmitted by environmenal elements such as sunshine and dirty water.In both settings,the care-seeking pathways were found to be strongly influenced by local customs and self-medication acquired from the informal sector.Conclusions:This study revealed that knowledge about the aetiology,transmission,symptoms,prevention and treatment of schistosomiasis among the populations in Korhogo and Kaedi is based on their local culture.Deep-rooted habits could therefore pose a significant obstacle to the elimination of schistosomiasis.展开更多
根据2017年9月20日至12月31日在毛里塔尼亚海域112个站点的调查数据,研究日本鲭(Scomber japonicus)的时空分布规律,并采用分位数回归的方法对随机选取的78%的站点数据建立其单位捕捞努力量渔获量(catch per unit effort,CPUE)与叶绿素...根据2017年9月20日至12月31日在毛里塔尼亚海域112个站点的调查数据,研究日本鲭(Scomber japonicus)的时空分布规律,并采用分位数回归的方法对随机选取的78%的站点数据建立其单位捕捞努力量渔获量(catch per unit effort,CPUE)与叶绿素a浓度、海表面温度、海表面盐度的关系模型,并利用剩余22%的站点数据验证所建立的模型的有效性,利用广义加性模型(GAM)评价环境因子的影响程度。根据分位数模型,计算日本鲭的栖息地综合指数(integrated habitat index,IHI),对建模站点和验证站点的CPUE实测值与预测值进行Wilcoxon(符号秩)检验,用Spearman相关系数结合双尾检验,检验其CPUE实测值与预测值之间的相关性,分析IHI与CPUE的关系。结果表明:海表面温度对日本鲭CPUE的影响最显著,其次是温盐的交互作用和海表面盐度,叶绿素a浓度对其无显著影响;建模站点和验证站点的CPUE预测值与实测值间皆无显著性差异;IHI模型对CPUE具有良好的预测效果;IHI分布较高的海域为17°25′W~17°45′W和20°15′N~20°45′N。根据上述结果,建议我国渔船在下半年作业时,作业范围应集中在17°25′W~17°45′W和20°15′N~20°45′N区域,以提高渔获产量。展开更多
文摘<strong>Introduction: </strong>Tracheotomy is a commonly performed procedure, but with very large disparities according to the teams, both in terms of frequency and modality (percutaneous or surgical), tracheotomy has been evolved with medical advances. The objective of this study was to clarify the indications and complications of emergency tracheotomies at the National hospital center (CHN) in Nouakchott Mauritania. <strong>Materials and Methods: </strong>It is a retrospective study of tracheotomies performed in the ENT department of the CHN during the period from January 1, 2010 to December 31, 2018. The indications and complications were noted, as well as the modalities and time of decannulation. <strong>Results:</strong> Tracheotomy was motivated by upper airway obstruction (UAO) in 139 (94%) cases (mean age 32.5 years), or the need for prolonged ventilation in 8 patients (median age 46 years). Sixteen (7%) early complications were noted with 5 untimely decannulations including one fatal and 5 obstructive plug responsible for another death. Six pneumothorax was observed. Fifteen (26%) late complications required additional surgery;7% (n = 11) of patients were decannulated with a mean duration of tracheotomy 26 months. In 19 (28%) cases of decannulations, the persistence of a tracheocutaneous fistula required surgery. <strong>Conclusion:</strong> Emergency tracheotomy is a survival gesture that is sure to be effective. A tracheotomy is not deprived of complications. Familiarity with the technique, the right choice of equipment, perfect knowledge of the anatomical relationships of the trachea, rigorous monitoring and postoperative care represent the main conditions for minimizing the risk of complications.
文摘Trauma care including abdominal trauma is a big challenge. It is associated with high morbidity and mortality and continues to be a public health problem worldwide. The main aims of our study were to assess the patterns and outcomes of our patients, and to describe our experience in management of abdominal trauma. This descriptive retrospective study was conducted in general surgery department at National Centre Hospital of Nouakchott in Mauritania. We recruited patients presented at our department with abdominal trauma (2012-2016). Out of 100 cases, 92% were men. Mean age: 22.78 years (5 - 70 years). Eighty percent of patients suffered of penetrating abdominal trauma. Stab injuries were the most frequent mechanism (60%). The commonest organ injury was small intestine (16%). Mortality has been strongly related to road traffic accidents. Cares of severe abdominal traumas are not common in our hospital, due to lack of required overall data. Emergency health system is needed to better care of trauma patients in Mauritania.
文摘<strong>Introduction:</strong> Primary open angle glaucoma (POAG) is an anterior optic neuropathy of chronic and progressive course, characterized by perimeter alteration and excavation of the specific optic disc. This neuropathy is usually accompanied by ocular hypertonia. The iridocorneal angle remains open in gonioscopy. POAG is the primary cause of irreversible blindness in adults around the world, posing a real public health and quality of life problem as well as an economic problem. The progressive and irreversible loss of vision makes POAG a disease that can lead to blindness. The main objective of our study is to describe the epidemiological, clinical and therapeutic aspects of primary open angle glaucoma in the ophthalmology department of the National Hospital Center of Nouakchott. <strong>Materials and Methods:</strong> It was a prospective descriptive study of 6 months (March 1<sup>st</sup> 2017 to August 30<sup>th</sup> 2017), on patients with a POAG with the presence of at least one of the three signs (intraocular pressure > 21 mmHg, papillary cup/disc vertical excavation ≥ 0.5 and a field altered apart from all other causes). All glaucoma patients seen during the study period benefited from a complete eye examination. The studied variables were the family history of glaucoma, age, intra ocular pressure (IOP) and pachymeter. <strong>Results:</strong> The mean age was 58.7 years. About 2/3 of the patients had a lower pachymeter to normal (63% of cases), a genetically thinner cornea results in an underestimation of the IOP measurement. The male was the most represented with a sex ratio M/F (1.42), the main characteristic factors were family history of glaucoma (39.7%), artery hypertension, diabetic and headache. The success rate of surgery was 69.8%, while 11% of our patients had refused any kind of treatment, no complications were noted, <strong>Conclusion:</strong> POAG is a multifactorial condition which can lead to blindness if not early diagnosed or if treatment is poorly conducted, hence the importance of prevention by screening and informing the population about this pathology.
文摘<strong>Introduction:</strong> Transurethral resection of the prostate (TURP), entered our service in October 2015, since then it became a part of the service daily activity. The aim of our study is to assess the acceptance of the technic by our patients and by the nursing staff and to analyze the results of our initial experience. <strong>Materials and Methods:</strong> Retrospective study over 14-month (October 2015 to December 2016);bringing together all the patients who received TURP. The inclusion criteria are to have benefited from a TURP in our service. The exclusion criteria all patients operated by other techniques. It was a monopolar resection of the prostate using a glycocolle loop, the size limit of the prostate was 65 cc or less. A questionnaire on the knowledge of the technique and its acceptance is made. The parameters studied the age of the patient;surgical indications;the course of the operation, the complications and the course. The frequency of TURP compared to other techniques and the demand for this technique by patients. The urinary catheter was left in place for 4 days, the patients were seen again on day 7 after the catheter was removed to assess the urine flow, a question regarding the opinion of the nursing staff was included and analyzed separately. <strong>Results:</strong> The total number of patients was 146;the mean age was 68.2 years. The main cause of consultation was urine retention 65%. The average duration of the intervention was 56 minutes. The average length of hospital stay was 28 hours. The urinary catheter was removed on day 4. Complications were bleeding in 7% of cases requiring blood transfusions. Failure to remove the indwelling catheter leads to revision via the transurethral route. The TURP syndrome was observed in 2 patients in our early patients but quickly resolved. The outcome was favorable in 75% of cases. Post operating management give satisfaction for nurse and acceptance was a success. <strong>Conclusion:</strong> TURP is now a routine surgical activity;it seems to have an upright place for BPH in our department;its impact on morbidity was remarkable.
文摘Most countries’ land use and land cover (LULC) are changing dramatically today. Most of these changes are related to the way humans and the environment interact. Various methodologies and data sources have been used in conjunction with remote sensing (RS) to categorize and map changes in LULC. This study used RS and Geographic Information System (GIS) tools to analyze LULC change and transitions from 1984 to 2022 in a tropical forested landscape in southwest Mauritania. Using a suitable and high-quality collection of Landsat satellite images. For the classification and creation of LULC maps for the selected periods, the supervised technique using a maximum likelihood classifier was used. The results indicated that there was a remarkable change in all classes of LULC, with an increase in all classes, except barren land, which had a tremendous decrease of −68.58% for the total study area. Therefore, for the total study area, an increase in agricultural land (221%), water bodies (118.46%), vegetation (57.50%), and built-up areas (14.65%) was observed. We believe that by informing policymakers, environmental managers, and the general public about the current changes, our study will help the region to establish appropriate land use rules that may lead to policy document development.
文摘Introduction: since its creation, our urology department has taken care of tumor pathologies in particular kidney cancer in adults;our goal is to study the clinical and therapeutic epidemiological profiles of adult kidney cancer in Mauritania. Materials and Methods: We carried out a retrospective study over a period of six years, from January 1, 2012 to December 31, 2017, including all cases of adult kidney cancer registered in the urology-andrology departments of the Cheikh Zayed Hospital and Pathological Anatomy of the National Hospital of Nouakchott (Mauritania). Results: we collected 50 cases of kidney cancer. The average annual incidence was 8.3 cases. The average age of the patients was 52.98 years with extremes of 18 and 84 years. There was a female predominance (52%) or 29 women for 21 men. Lumbar pain was the most frequent clinical expression, more than half of the patients had symptoms over a period of at least 12 months before the first consultation. The left kidney was the most frequently affected. The right localization was demonstrated in 23 patients, the extension assessment was made with thoraco-abdomino-pelvic CT in 40 patients. Twelve patients had a tumor localized in the kidney. The extension assessment had made it possible to objectify the existence of metastases in 17 of our patients (37%). The preferred locations of these metastases were pulmonary and hepatic. Surgical intervention was performed in 44 patients (88%), of whom 36 underwent radical nephrectomy (72%), and two patients underwent partial nephrectomy (4.5%). Surgical abstention was decided from the outset in 6 patients (13.6%). None of our patients had received treatment with anti-angiogenics. The histological type most observed in our patients was renal cell carcinoma, observed in 34 patients, or 77.72%. At the time of the study, more than a third of the patients had died. The mortality rate in our series had reached 24%. A specific survival rate could not be assessed due to lack of information in the files and significant numbers of patients lost to follow-up at the time of the study. Conclusion: adult kidney cancer in Mauritania is characterized by its low incidence, its occurrence in a relatively young population, its female predominance, its often late diagnosis at locally advanced and metastatic stages, and the treatment is the most often surgical.
文摘The aim of our study was to determine epidemiological, clinical and therapeutic profile of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania. All cases of colorectal cancers histologically confirmed were included. The Astler and Coller classification was used to classify lesions by level of extension. Results: 225 patients were included with a sex ratio (M/F) of 1.39, an average age of 52.3 years. Location of the lesion was rectal (37.7%) and colonic (62.3%). Clinical manifestations were dominated by rectal bleeding (26.9%), occlusive syndrome (16.5%) and transit disorders (11.6%). Endoscopic lesions were of stenosing (45.2%), ulcero-burgeoning (39%), ulcerous (7.5%) and burgeoning (4.7%) types. Histological profiles were adenocarcinoma (88.9%), carcinoma (3.1%) and lymphoma (2.6%). The work-up for extension revealed metastasis in 33.6% of cases. These were stage B (49%) and C (36%) among the 95 cancers that received the Astler and Coller classification. The treatment was curative (80.83%) and palliative (19.16%). Conclusion: Colorectal cancer is a reality in Africa. However, its diagnosis still remains delayed, which increases the prognosis, hence the need to promote screening tests.
基金the“National Key Research and Development Program of China”(Project NO.2016YFD0400202-8).
文摘In this study,the effects of chemical refining on the physicochemical indices,environmental pollutants,lipid functional groups,relaxation characteristics,fatty acid profiles,and triglyceride(TG)molecular species in crude oil extracted from small fish in Mauritania were evaluated.The acid,peroxide,and iodine values of crude oil were identified as 5.52 mg KOH/g,1.73 meq/kg,and 200.78 g/100 g oil,respectively.After refining,these values were determined to be 0.29 mg KOH/g,0.76 meq/kg,and 210.80 g/100 g oil,respectively.The polychlorinated biphenyls and arsenic content of crude oil were identified as 32.30μg/kg and 1.00 mg/kg,respectively.After refining,these were not detected.The content of eicosapentaenoic acid(EPA)and docosahexaenoic acid(DHA)accounted for as much as 87.55%of the polyunsaturated fatty acids in the refined oil,indicating that high-quality fish oil is suitable as a food supplement.The correlation coefficient of the infrared spectra before and after refining was 0.968,and the relaxation time and peak shape data were almost similar before and after purification.Meanwhile,there were no significant differences(P≥0.05)in fatty acid profiles between the crude and refined oils,except for C16:0(P<0.01).Based on UPLC-Q E-MS/MS detection,137 TG molecules were identified in both crude and refined oils.Among the detected TG molecular species,64 contained EPA or DHA,which accounted for 46.83%and 46.00%of the total TG content in crude and refined oils,respectively.After refining,the content of the molecular species decreased by 31.95 mg/10 g,among which the three most variable molecular species were TG(16:0/18:1/22:6),(16:1/16:2/18:1),and(18:4/16:0/20:5),accounting for 29.26%of the decline of the molecular species.Overall,the refining process had little effect on the fatty acid profile and distribution of TG molecular species in fish oil.
基金This project received financial support from the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases(TDR)and the Canadian International Development Research Centre(IDRC)(grant no.NB20283 to Dr.Brama Koné)The funders had no role in the study design,data collection and analyses,decision to publish,or preparation of the paper.
文摘Background:Among parasitic infections,schistosomiasis ranks second after malaria in terms of worldwide morbidity.Despite efforts to contain transmission,more than 230 million people are infected,of which 85%live in Sub-Saharan Africa.While the epidemiologic characteristics of schistosomiasis have been extensively studied across endemic settings,social factors have been paid less attention.The current study assesses community knowledge of schistosomiasis causes,transmission,signs,symptoms and prevention,as well as healthcare-seeking behaviours in two West African settings,with the aim of strengthening schistosomiasis control interventions.Methods:From August 2014 to June 2015,we conducted two cross-sectional surveys in Korhogo,Cote d’Ivoire and Kaedi,Mauritania.We applied a questionnaire to collect quantitative data at the household level in Korhogo(n=1456)and Kaedi(n=1453).Focus group discussions(Korhogo:n=32,Kaedi:n=32)and participatory photography(photovoice)(Korhogo:n=16,Kaedi:n=16)were conducted within the communities to gather qualitative data.In addition,semi-structured interviews were used to discuss with key informants from control programmes,nongovernmental organizations and health districts(Korhogo:n=8,Kaedi:n=7).Results:The study demonstrated that schistosomiasis is not well known by the communities;64.1%claimed to know the causes of the disease,but the reality is different.This knowledge is more from cultural than biomedical source.It was observed that social construction of the disease is different from the biomedical definition.In Korhogo,schistosomiasis was often associated with several other diseases,notably stomach ulcer and gonorrhoea.The populations believe that schistosomiasis is caused by exposure to goat or dog urine in the environment.In Kaedi,schistosomiasis is considered as a disease transmitted by environmenal elements such as sunshine and dirty water.In both settings,the care-seeking pathways were found to be strongly influenced by local customs and self-medication acquired from the informal sector.Conclusions:This study revealed that knowledge about the aetiology,transmission,symptoms,prevention and treatment of schistosomiasis among the populations in Korhogo and Kaedi is based on their local culture.Deep-rooted habits could therefore pose a significant obstacle to the elimination of schistosomiasis.
文摘根据2017年9月20日至12月31日在毛里塔尼亚海域112个站点的调查数据,研究日本鲭(Scomber japonicus)的时空分布规律,并采用分位数回归的方法对随机选取的78%的站点数据建立其单位捕捞努力量渔获量(catch per unit effort,CPUE)与叶绿素a浓度、海表面温度、海表面盐度的关系模型,并利用剩余22%的站点数据验证所建立的模型的有效性,利用广义加性模型(GAM)评价环境因子的影响程度。根据分位数模型,计算日本鲭的栖息地综合指数(integrated habitat index,IHI),对建模站点和验证站点的CPUE实测值与预测值进行Wilcoxon(符号秩)检验,用Spearman相关系数结合双尾检验,检验其CPUE实测值与预测值之间的相关性,分析IHI与CPUE的关系。结果表明:海表面温度对日本鲭CPUE的影响最显著,其次是温盐的交互作用和海表面盐度,叶绿素a浓度对其无显著影响;建模站点和验证站点的CPUE预测值与实测值间皆无显著性差异;IHI模型对CPUE具有良好的预测效果;IHI分布较高的海域为17°25′W~17°45′W和20°15′N~20°45′N。根据上述结果,建议我国渔船在下半年作业时,作业范围应集中在17°25′W~17°45′W和20°15′N~20°45′N区域,以提高渔获产量。
