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Properties of Sensitive Materials Mainly Composed of ZnO 被引量:1
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作者 Mengkui WANG, Xiao’an YANG and Fuzhong WANG (Department of Physics, Jinzhou Teachers College, Jinzhou 121003, China) Ke SUN (Department of Physics, Northeastern University, Shenyang 110006, China) 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2000年第2期204-204,共1页
Sensitive materials mainly composed of ZnO and their multi-functional properties were investigated. The temperature extent of linear resistance, non-linear deviation and endurance ability of surge energy were further ... Sensitive materials mainly composed of ZnO and their multi-functional properties were investigated. The temperature extent of linear resistance, non-linear deviation and endurance ability of surge energy were further discussed. The effect of Mg^2+, AI^3+ and Si^4+, which could be solid solutioned in ZnO grain and the function of Y^3+ ion segregated out in grain boundary were studied as well. The function of Ti was analyzed emphatically. 展开更多
关键词 Properties of Sensitive Materials mainly Composed of ZnO
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Clinical Observarion on 50 Cases of Long-Standing Infantile Diarrhea Treated Mainly with Massotherapy
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作者 Jiang Qilong,Liu xiaoping(Qiqihar Municipal Hospital of Traditional Chinese Medicine,Heilongjiang,161000) 《中国针灸》 CAS CSCD 北大核心 1995年第S2期326-326,共1页
ClinicalObservarionon50CasesofLong-StandingInfantileDiarrheaTreatedMainlywithMassotherapy¥JiangQilong;Liuxia... ClinicalObservarionon50CasesofLong-StandingInfantileDiarrheaTreatedMainlywithMassotherapy¥JiangQilong;Liuxiaoping(QiqiharMuni... 展开更多
关键词 STANDING Observarion DIARRHEA INFANTILE Long mainly Massotherapy CASES CLINICAL TREATED
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mainly及其它
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作者 任喜 《语言教育》 1994年第6期25-26,共2页
largely,greatly,mostly,chiefly,mainly,principally和generally这7个副词都表示有关事物中最为主要、最为重要、起决定作用、占主导地位或在数量上占多数等意思,但它们之间也是有区别的: 1.largely强调数量或广度,常表示很丰富,量很大... largely,greatly,mostly,chiefly,mainly,principally和generally这7个副词都表示有关事物中最为主要、最为重要、起决定作用、占主导地位或在数量上占多数等意思,但它们之间也是有区别的: 1.largely强调数量或广度,常表示很丰富,量很大,所占比例很高而超过了其它的成分,有主要地、大半地、大部分等意思。例如: 展开更多
关键词 mostly largely mainly REMEMBER MISTAKE THINK WRITE 我不知道 basket BATTLE
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Clinical Observation on the Efficacy Enhancing and Toxicity Attenuating Effect of Nuzhen Yangyin Granule to the Anti-Parkinsonism Therapy Mainly with Medopa
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作者 胡学军 杨晓苏 +4 位作者 杨旭光 周东阳 谭光波 伍大华 阳立 《Chinese Journal of Integrated Traditional and Western Medicine》 2004年第1期28-28,共1页
Objective: To observe and assess the efficacy enhancing and toxicity attenuating effect of Nuzhen Yangyin Granule (NYG) to the anti-parkinsonism (paralysis agitans) therapy with medopa and ar-tane. Methods: Adopting t... Objective: To observe and assess the efficacy enhancing and toxicity attenuating effect of Nuzhen Yangyin Granule (NYG) to the anti-parkinsonism (paralysis agitans) therapy with medopa and ar-tane. Methods: Adopting the randomized double-blinded method, the effect of adding NYG to 30 patients with Parkinsonism in the treated group, 展开更多
关键词 Clinical Observation on the Efficacy Enhancing and Toxicity Attenuating Effect of Nuzhen Yangyin Granule to the Anti-Parkinsonism Therapy mainly with Medopa
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Design and Control of a Bionic Inspection Robot for Suspension Bridge Main Cables
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作者 Shengkai Liu Chao Wang +1 位作者 Xiaoqiang Yuan Ning Ding 《Journal of Bionic Engineering》 2026年第1期159-174,共16页
The main cable is the primary load-bearing component of a suspension bridge,continuously exposed to harsh environmental conditions,such as wind and rain,throughout the year.These adverse conditions contribute to varyi... The main cable is the primary load-bearing component of a suspension bridge,continuously exposed to harsh environmental conditions,such as wind and rain,throughout the year.These adverse conditions contribute to varying degrees of degradation and damage to the main cable,necessitating regular inspections to prevent catastrophic failures.Traditional manual inspection methods not only suffer from low efficiency but also pose significant safety risks to personnel.To address these challenges and ensure the safe and effective inspection of suspension bridge main cables,this study introduces a novel cooperative climbing robot,designated as Main Cable Robot Version II(CCRobot-M-II),inspired by the locomotion of the inchworm.The robot employs an alternating opening and closing mechanism of four gripper sets,mimicking the inchworm's movement to achieve efficient crawling along the suspension bridge handrails.This paper provides a comprehensive analysis of the structural design,key components,and motion mechanisms of CCRobot-M-II.A detailed force analysis of the robot's crawling process is also presented,followed by the design of the control system and the development of an efficient motion control algorithm.Laboratory experiments demonstrate that the robot achieves a positional error of 00.64%during crawling,with a maximum average crawling speed of 7.6 m/min.Furthermore,the biomimetic design enables the robot to overcome obstacles up to 30 mm in height and possess the capability to handle suspension bridge cables with spans ranging from 740 to 1100 mm.Finally,CCRobot-M-II successfully conducted an inspection of the main cable on a suspension bridge,marking the world's first successful deployment of a climbing robot for main cable inspection on a suspension bridge. 展开更多
关键词 Bionic design Suspension bridge Main cable inspection Climbing robot Motion control
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Photoacoustic imaging and main lobe width analysis for enhancing microwave ablation monitoring of liver tissue
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作者 Min Wan Yameng Zhang +4 位作者 Shihao Tang Zhiyu Qian Fan Gao Yamin Yang Weitao Li 《Journal of Innovative Optical Health Sciences》 2026年第2期129-140,共12页
Microwave ablation(MWA)is a minimally invasive technique for treating hepatic tumors,necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues.This study explores the pot... Microwave ablation(MWA)is a minimally invasive technique for treating hepatic tumors,necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues.This study explores the potential of photoacoustic imaging(PAI)in monitoring MWA by examining ex vivo porcine liver tissues.In this study,a comprehensive analysis of photoacoustic signals was performed to compare the main lobe width(MLW)between ablated and normal regions in porcine liver tissue.Histological staining with succinate dehydrogenase(SDH)and shear wave elastography(SWE)were employed to validate the changes in tissue elasticity after ablation.The analysis demonstrated a notable reduction in the MLW of the average A-lines in ablated tissues compared to nonablated regions(p<0.01).This reduction,attributed to increased tissue density and enhanced elasticity,indicates accelerated sound propagation in thermally ablated areas,which then serves as a critical parameter for mapping tissue characteristics.The reconstruction of the MLW distribution successfully delineated the ablated regions,and was consistent with the results of SDH staining and SWE.In addition,MLW-based imaging exhibited higher spatial resolution compared to SWE.Incorporating MLW analysis into PAI may be a promising strategy to improve the accuracy and effectiveness of MWA monitoring in clinical settings. 展开更多
关键词 Photoacoustic imaging main lobe width microwave ablation tissue density shear wave elastography
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Assessing neotectonic deformation and terrain evolution through geospatial morphometric techniques across the MBT zone,NW Himalaya
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作者 CHANGMAI Jayshree PATIDAR Atul Kumar KOTHYARI Girish Ch 《Journal of Mountain Science》 2026年第3期1079-1104,共26页
The transitional zone between the Sub-Himalaya and the Lesser Himalaya is delineated by the Main Boundary Thrust(MBT)to the north and the Himalayan Frontal Thrust(HFT)to the south.The MBT acts as a major topographic b... The transitional zone between the Sub-Himalaya and the Lesser Himalaya is delineated by the Main Boundary Thrust(MBT)to the north and the Himalayan Frontal Thrust(HFT)to the south.The MBT acts as a major topographic barrier that exerts significant control over longitudinal river valleys and sediment dispersal patterns.This region exhibits pronounced fluvial responses shaped by the interplay of tectonic activity and climatic processes.The present study addresses the need for detailed micro-scale morphometric analysis in this zone to better understand ongoing landscape deformation and neotectonic signatures.A multidisciplinary approach integrating geospatial morphometric techniques with field-based evidence has been employed to investigate terrain evolution.Quantitative morphometric assessments were conducted for 16 sub-basins within an active segment of the MBT,bounded by the Jakhan River to the east and the Giri River to the west.Dimensional changes driven by tectonic uplift and accelerated erosion/incision were evaluated using the hypsometric integral(HI),with most values falling below 0.50,indicating that the drainage basins are in an equilibrium stage.Basin shape(Bs)values range from 0.88 to 6.79,supporting the occurrence of accelerated erosional processes.The stream length gradient index(SL)exhibits values between 86 and 816,suggesting rapid uplift and incision.Similarly,computed values of the Chi(χ)coefficient(479-3706)and the steepness index(Ksn;63-214)reflect differential erosion and strong tectonic control on drainage network evolution.The spatial distribution of tectonic deformation was statistically evaluated using a correlation matrix based on the Relative Index of Active Tectonics(RIAT).The results reveal that approximately 50.33%and 16.25%of the study area fall into high and moderate activity zones,respectively,which is corroborated by historical earthquake records and geomorphic evidence.Neotectonic signatures are preserved in the landscape as river terraces,displaced or tilted strata,V-shaped valleys,river offsets,knickpoints,hanging valleys,and channel migration along the strike of the MBT.These findings underscore the significant role of neotectonics in landform evolution and offer valuable insights for geohazard assessment and mitigation strategies in the rapidly developing foothill regions of the Himalaya. 展开更多
关键词 NEOTECTONICS Morphometric analysis Main Boundary Thrust Fluvial response Relative Index of Active Tectonics(RIAT) Landscape evolution HIMALAYA
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The world's first continuous small-radius spiral ramp excavated by tunnel boring machine at China's Beishan Underground Laboratory for high-level radioactive waste disposal
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作者 Ju Wang Jianguo Wang +1 位作者 Xingguang Zhao Jihong Wang 《Deep Underground Science and Engineering》 2026年第1期1-3,共3页
China has achieved a major engineering milestone in the construction of the Beishan Underground Research Laboratory(URL)for geological disposal of high-level radioactive waste(HLW).On December 26,2025,the project team... China has achieved a major engineering milestone in the construction of the Beishan Underground Research Laboratory(URL)for geological disposal of high-level radioactive waste(HLW).On December 26,2025,the project team successfully completed the excavation of the world's first deep,continuous small-radius,steep spiral ramp by a tunnel boring machine(TBM)named Beishan No.1,which marked the completion of the underground main structure of Beishan URL. 展开更多
关键词 underground main structure continuous small radius spiral ramp Beishan Underground Laboratory tunnel boring machine tunnel boring machine tbm named high level radioactive waste disposal engineering milestone
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The Life Cycle of the Family and the Law Governing Cyclical Fluctuations in the Family Economy—An Empirical Study Based Mainly on Information Related to China's National Minorities
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《Social Sciences in China》 2001年第2期77-89,共13页
关键词 An Empirical Study Based mainly on Information Related to China’s National Minorities
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Observation on the clinical efficacy of spasmodic torticollis treated with matrix needling technique and acupuncture at “Wuxin points” mainly
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作者 徐彦龙 《China Medical Abstracts(Internal Medicine)》 2013年第3期134-135,共2页
Objective To compare the difference in the efficacy on spasmodic torticollis between matrix needling technique combined with puncturing"Wuxin points"and the local injection of botox type A.Methods Forty-two ... Objective To compare the difference in the efficacy on spasmodic torticollis between matrix needling technique combined with puncturing"Wuxin points"and the local injection of botox type A.Methods Forty-two cases were randomized into an acupuncture group and a 展开更多
关键词 ACUPUNCTURE Wuxin POINTS mainly OBSERVATION visit markedly MUSCULAR bilateral WEAKNESS injected
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西部县域3-5岁儿童复述故事能力的发展研究
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作者 杨帆 李梅 张曼曼 《陕西学前师范学院学报》 2025年第10期107-116,共10页
复述故事为儿童创造性地构建和诠释故事内容提供了一个窗口。基于此,本研究选取了400名3-5岁的儿童,采用MAIN叙事语言评估工具,从故事表达和理解两个维度全面评估儿童复述故事的叙事能力。研究发现,3-5岁儿童复述故事的叙事能力随年龄... 复述故事为儿童创造性地构建和诠释故事内容提供了一个窗口。基于此,本研究选取了400名3-5岁的儿童,采用MAIN叙事语言评估工具,从故事表达和理解两个维度全面评估儿童复述故事的叙事能力。研究发现,3-5岁儿童复述故事的叙事能力随年龄增长显著提升,4-5岁为快速发展期;3-5岁儿童随着年龄增长故事表达能力不断提升,但故事结构复杂性发展最为缓慢;故事理解能力存在显著的性别差异,女生在角色目标理解和心理状态推理方面普遍优于男生。因此,应鼓励成人积极有效的示范,提升儿童故事表达能力;针对不同年龄阶段,选择不同结构类型的图画书,提升结构复杂性;采用多元引导和复述策略,促进不同性别儿童对故事内心状态的理解。 展开更多
关键词 复述故事 故事表达 故事理解 MAIN
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The Fentanyl Crisis in the U.S.: Truth and Solutions
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作者 Shan Yehua 《Foreign Affairs Journal》 2025年第1期59-71,112-117,共19页
I.The Fentanyl Crisis in the U.S.The development and spread of the fentanyl crisis in the U.S.Recent years have seen a deteriorating narcotics situation in the U.S.and serious social problems arising therefrom.From 19... I.The Fentanyl Crisis in the U.S.The development and spread of the fentanyl crisis in the U.S.Recent years have seen a deteriorating narcotics situation in the U.S.and serious social problems arising therefrom.From 1999 to 2012,deaths from synthetic opioids(mainly fentanylrelated substances)overdose in the U.S.increased by 8%annually. 展开更多
关键词 synthetic opioids fentanyl crisis social problems overdose deaths narcotics situation synthetic opioids mainly
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Main factors controlling unconventional gas enrichment and high production in the first member of Permian Maokou Formation,southeastern Sichuan Basin,SW China 被引量:2
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作者 HE Guisong SUN Bin +4 位作者 GAO Yuqiao ZHANG Peixian ZHANG Zhiping CAI Xiao XIA Wei 《Petroleum Exploration and Development》 2025年第2期408-421,共14页
Based on the data of drilling,logging,experiment and gas testing in the Nanchuan area,southeastern Sichuan Basin,the hydrocarbon generation potential,gas genesis,occurrence state,migration,preservation conditions,pore... Based on the data of drilling,logging,experiment and gas testing in the Nanchuan area,southeastern Sichuan Basin,the hydrocarbon generation potential,gas genesis,occurrence state,migration,preservation conditions,pore and fracture features and accumulation evolution of the first member of Permian Maokou Formation(Mao 1 Member)are systematically studied,and the main controlling factors of unconventional gas enrichment and high production in marlstone assemblage of Mao 1 Member are discussed.(1)The enrichment and high yield of unconventional natural gas in the Mao 1 Member are controlled by three factors:carbon-rich fabric controlling hydrocarbon generation potential,good preservation controlling enrichment,and natural fracture controlling production.(2)The carbonate rocks of Mao 1 Member with carbon rich fabric have significant gas potential,exhibiting characteristics of self-generation and self-storage,which lays the material foundation for natural gas accumulation.(3)The occurrence state of natural gas is mainly free gas,which is prone to lateral migration,and good storage conditions are the key to natural gas enrichment.Positive structure is more conducive to natural gas accumulation,and a good compartment is created jointly by the self-sealing property of the Mao 1 Member and its top and bottom sealing property in monoclinal area,which is favorable for gas accumulation by retention.(4)Natural fractures are the main reservoir space and flow channel,and the more developed natural fractures are,the more conducive to the formation of high-quality porous-fractured reservoirs and the accumulation of natural gas,which is the core of controlling production.(5)The accumulation model of unconventional natural gas is proposed as“self-generation and self-storage,preservation controlling richness,and fractures controlling production”.(6)Identifying fracture development areas with good preservation conditions is the key to successful exploration,and implementing horizontal well staged acidizing and fracturing is an important means to increase production and efficiency.The study results are of referential significance for further understanding the natural gas enrichment in the Mao 1 Member and guiding the efficient exploration and development of new types of unconventional natural gas. 展开更多
关键词 Sichuan Basin PERMIAN Maokou Formation unconventional natural gas main controlling factors of enrichment and high production accumulation model carbonate rock southeastern Sichuan Basin
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Statistical characteristics and classification of ionospheric mid-latitude trough as revealed by the observations of DMSP-F18
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作者 Yi Liu JiuHou Lei +1 位作者 FuQing Huang Su Zhou 《Earth and Planetary Physics》 EI CAS 2025年第1期137-147,共11页
Statistical characteristics and the classification of the topside ionospheric mid-latitude trough are systemically analyzed,using observations from the Defense Meteorological Satellite Program F18(DMSP-F18)satellite.T... Statistical characteristics and the classification of the topside ionospheric mid-latitude trough are systemically analyzed,using observations from the Defense Meteorological Satellite Program F18(DMSP-F18)satellite.The data was obtained at an altitude of around 860 km in near polar orbit,throughout 2013.Our study identified the auroral boundary based on the in-situ electron density and electron spectrum,allowing us to precisely determine the location of the mid-latitude trough.This differs from most previous works,which only use Total Electron Content(TEC)or in-situ electron density.In our study,the troughs exhibited a higher occurrence rate in local winter than in summer,and extended to lower latitudes with increasing geomagnetic activity.It was found that the ionospheric mid-latitude trough,which is associated with temperature changes or enhanced ion drift,exhibited distinct characteristics.Specifically,the ionospheric mid-latitude troughs related to electron temperature(Te)peak were located more equatorward of auroral oval boundary in winter than in summer.The ionospheric mid-latitude troughs related to Te-maximum were less frequently observed at 60−70°S magnetic latitude and 90−240°E longitude.Furthermore,the troughs related to ion temperature(Ti)maximums were observed at relatively higher latitudes,occurring more frequently in winter.In addition,the troughs related to ion velocity(Vi)maximums could be observed in all seasons.The troughs with the maximum-Ti and maximum-Vi were located closer to the equatorward boundary of the auroral oval at the nightside,and in both hemispheres.This implies that enhanced ion drift velocity contributes to increased collisional frictional heating and enhanced ion temperatures,resulting in a density depletion within the trough region. 展开更多
关键词 topside ionosphere mid-latitude trough ionospheric main trough auroral oval boundary temperature maximum
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Enhanced Ion Sampling Techniques for In-situ Neutral Gas and Low-energy Ions Exploration of Main-belt Comet
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作者 WANG Xinyue ZHANG Aibing +4 位作者 SU Bin DU Dan KONG Linggao TIAN Zheng ZHENG Xiangzhi 《空间科学学报》 北大核心 2025年第3期749-760,共12页
One of the detection objectives of the Chinese Asteroid Exploration mission is to investigate the space environment near the Main-belt Comet(MBC,Active Asteroid)311P/PANSTARRS.This paper outlines the scientific object... One of the detection objectives of the Chinese Asteroid Exploration mission is to investigate the space environment near the Main-belt Comet(MBC,Active Asteroid)311P/PANSTARRS.This paper outlines the scientific objectives,measurement targets,and measurement requirements for the proposed Gas and Ion Analyzer(GIA).The GIA is designed for in-situ mass spectrometry of neutral gases and low-energy ions,such as hydrogen,carbon,and oxygen,in the vicinity of 311P.Ion sampling techniques are essential for the GIA's Time-of-Flight(TOF)mass analysis capabilities.In this paper,we present an enhanced ion sampling technique through the development of an ion attraction model and an ion source model.The ion attraction model demonstrates that adjusting attraction grid voltage can enhance the detection efficiency of low-energy ions and mitigate the repulsive force of ions during sampling,which is influenced by the satellite's surface positive charging.The ion source model simulates the processes of gas ionization and ion multiplication.Simulation results indicate that the GIA can achieve a lower pressure limit below 10-13Pa and possess a dynamic range exceeding 10~9.These performances ensure the generation of ions with stable and consistent current,which is crucial for high-resolution and broad dynamic range mass spectrometer analysis.Preliminary testing experiments have verified GIA's capability to detect gas compositions such as H2O and N2.In-situ measurements near 311P using GIA are expected to significantly contribute to our understanding of asteroid activity mechanisms,the evolution of the atmospheric and ionized environments of main-belt comets,the interactions with solar wind,and the origin of Earth's water. 展开更多
关键词 neutral gas low energy ions sampling techniques ion sampling techniques investigate space environment main belt comet gas ion analyzer gia situ measurement
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Hydraulic Sliding Formwork Construction Technology for Main Pier Columns of Highway Bridges
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作者 Guangpu Dong Liang Wang 《Journal of World Architecture》 2025年第1期1-6,共6页
Aiming at the problems of difficulty in balancing construction efficiency and quality,as well as the high safety risks of working at heights during the construction of main piers for highway bridges,this study takes a... Aiming at the problems of difficulty in balancing construction efficiency and quality,as well as the high safety risks of working at heights during the construction of main piers for highway bridges,this study takes a specific bridge project as an example to introduce the technology of hydraulically sliding formwork for the construction of main piers of highway bridges.An in-depth analysis of the project’s construction process found that this technology can effectively improve construction efficiency,ensure the quality of concrete pouring,and significantly reduce the potential safety hazards of working at heights.It provides a reliable technical solution for constructing the main piers of highway bridges and has important reference significance for similar projects. 展开更多
关键词 Highway bridges Main piers Hydraulic pressure SLIDING FORMWORK
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Textile design statements with‘among-us’:Heimtextil meets Milan Design Week
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《China Textile》 2025年第2期50-51,共2页
Frankfurt am Main,7 April 2o25.Textile interior design at its best is an inte-gral part of Heimtextil,the most inftuentiailand giobai platform for home and contracttextiles as well as textile design.PatriciaUrquiola e... Frankfurt am Main,7 April 2o25.Textile interior design at its best is an inte-gral part of Heimtextil,the most inftuentiailand giobai platform for home and contracttextiles as well as textile design.PatriciaUrquiola expressed this spectacularly inJaruary in Frankfuirt with her installation'among-us'. 展开更多
关键词 interior design giobai platform textile design Frankfurt am Main Us HEIMTEXTIL Milan Design Week Patricia Urquiola
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Topic Sentencesin a Passage
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作者 侯明璐 《疯狂英语(双语世界)》 2025年第4期17-20,36,共5页
I.What are topic sentences in a passage?A topic sentence is the main idea of a paragraph.It tells readers what the paragraph will talk about.Usually,the topic sentence is the first sentence of a paragraph,but sometime... I.What are topic sentences in a passage?A topic sentence is the main idea of a paragraph.It tells readers what the paragraph will talk about.Usually,the topic sentence is the first sentence of a paragraph,but sometimes it can come in the middle or at the end.A good topic sentence helps readers understand the writer's purpose quickly. 展开更多
关键词 PARAGRAPH main idea writers purpose topic sentence
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End-to-end algorithm research in PACT—from signal processing to reconstruction solution to image processing:A review
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作者 JinJin Cheng Shuilin Wang +12 位作者 Shirui Dong Yang Wang Xuyu Fu Jichao Zhang Wenkai Li Siyu Chen Silue Zeng Yaguang Ren Xiaohui Ma Jinhai Liu Mingjian Sun Rongkang Gao Chengbo Liu 《Journal of Innovative Optical Health Sciences》 2025年第4期19-61,共43页
Photoacoustic computed tomography(PACT)is an innovative biomedical imaging technique that has gained significant application in the field of biomedicine due to its ability to visualize optical contrast with high resol... Photoacoustic computed tomography(PACT)is an innovative biomedical imaging technique that has gained significant application in the field of biomedicine due to its ability to visualize optical contrast with high resolution and deep tissue penetration.However,the inherent challenges associated with photoacoustic signal excitation,propagation and detection often result in suboptimal image quality.To overcome these limitations,researchers have developed various advanced algorithms that span the entire image reconstruction pipeline.This review paper aims to present a detailed analysis of the latest advancements in PACT algorithms and synthesize these algorithms into a coherent framework.We provide tripartite analysis—from signal processing to reconstruction solution to image processing,covering a spectrum of techniques.The principles and methodologies,as well as their applicability and limitations,are thoroughly discussed.The primary objective of this study is to provide a thorough review of advanced algorithms applicable to PACT,offering both theoretical foundations and practical guidance for enhancing the imaging effect of PACT. 展开更多
关键词 Photoacoustic computed tomography PRE-PROCESSING main transformation POSTPROCESSING deep learning
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Identification of QTL-by-environment interaction by controlling polygenic background effect
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作者 Fuping Zhao Lixian Wang Shizhong Xu 《Journal of Genetics and Genomics》 2025年第7期915-926,共12页
The quantitative trait loci(QTL)-by-environment(Q × E) interaction effect is hard to detect because there are no effective ways to control the genomic background. In this study, we propose a linear mixed model th... The quantitative trait loci(QTL)-by-environment(Q × E) interaction effect is hard to detect because there are no effective ways to control the genomic background. In this study, we propose a linear mixed model that simultaneously analyzes data from multiple environments to detect Q × E interactions. This model incorporates two different kinship matrices derived from the genome-wide markers to control both main and interaction polygenic background effects. Simulation studies demonstrate that our approach is more powerful than the meta-analysis and inclusive composite interval mapping methods. We further analyze four agronomic traits of rice across four environments. A main effect QTL is identified for 1000-grain weight(KGW), while no QTL are found for tiller number. Additionally, a large QTL with a significant Q × E interaction is detected on chromosome 7 affecting grain number, yield, and KGW. This region harbors two important genes, PROG1 and Ghd7. Furthermore, we apply our mixed model to analyze lodging in barley across six environments. The six regions exhibiting Q × E interaction effects identified by our approach overlap with the SNPs previously identified using EM and MCMC-based Bayesian methods, further validating the robustness of our approach. Both simulation studies and empirical data analyses show that our method outperforms all other methods compared. 展开更多
关键词 Q×E interaction Main effect META-ANALYSIS Mixed model Polygenic background
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