Objective: The aim was to show that Minimally Invasive total arterial revascularization for left main stem coronary artery disease, via a left anterior Mini thoracotomy using bilateral internal thoracic arteries is fe...Objective: The aim was to show that Minimally Invasive total arterial revascularization for left main stem coronary artery disease, via a left anterior Mini thoracotomy using bilateral internal thoracic arteries is feasible, reproducible and safe. Further, there has been no exclusive data or experience with minimally invasive coronary artery bypass grafting in left main stem disease. Methods: From April 2019 to March 2024, 41 patients with left main stem stenosis, left main equivalent disease and unprotected left main with triple vessel disease underwent off pump minimally invasive multivessel coronary artery bypass grafting using either in situ pedicled Bilateral Internal Thoracic arteries or Left and Right Internal Thoracic artery Y composite conduits at three centers. Bilateral Internal Thoracic arteries were harvested under direct vision. All patients had an Intra-Aortic Balloon Pump inserted via the femoral artery prior to induction of anesthesia, to prevent any hemodynamic instability, arrhythmias, and was removed following completion of the procedure in the operating room without any complications. Efficacy and outcomes were evaluated by i) Primary (MACCE)-Major Adverse Cardiac and Cardiovascular events and ii) Secondary outcome measures including total length of stay, return to full physical activity and quality of life. Mean follow-up was 1.4 years (Maximum was 2.5 years). Results: 41 patients with left main stem coronary artery stenosis, underwent total arterial revascularization using bilateral internal thoracic arteries. Left main stem stenosis was present in 29 patients, Unprotected left main stem stenosis with triple vessel disease in 7 and left main equivalence in 5 patients. In this cohort, 29 patients with only left main stem stenosis had 2 grafts each, 7 patients with left main and triple vessel disease had 3 grafts and 5 patients with left main equivalent disease had 2 grafts respectively. The average number of grafts was 2.2. One patient was converted to open sternotomy as an emergency because of hemodynamic instability and myocardial revascularization was done on cardiopulmonary bypass (2.2%). The average hospital stay was 3.7 days. Ejection fraction was 45% ± 5%. There was one mortality (2.2%) but no major morbidity. The average ICU and hospital stay was 24 ± 4 hours and 3.7 days. All patients were free from major adverse cardiac and cerebrovascular events at follow-up. Conclusions: Multivessel total arterial revascularization using left and right internal thoracic arteries, was performed via a left anterior Mini thoracotomy on patients with left main stem disease and showed that it was safe, reproducible and will help extend the armamentarium of the surgeon in minimally invasive Coronary artery bypass grafting. Concomitantly it helped enhance the potential for shorter hospital stay, increased survival, decreased morbidity, and earlier return to full activity. Furthermore, the safety, efficacy, and outcomes of minimally invasive coronary artery bypass grafting in this high-risk group evaluated by primary and secondary outcome measures have been good in this study.展开更多
It has become general for surface waters being polluted by micro organic compounds. In order to know the current pollution situation and the properties of micro organic compounds in the Changjiang River, a test was pe...It has become general for surface waters being polluted by micro organic compounds. In order to know the current pollution situation and the properties of micro organic compounds in the Changjiang River, a test was performed on micro organic compounds in the water, bottom material and fish bodies which were sampled from major city river reaches of the Changjiang River. Based on the test result, researchers described and analyzed the sorts, concentration level and distribution features of micro organic compounds. A comprehensive evaluation was conducted by adopting the method of MEG (Multimedia Environmental Goals). The study indicated that ① the water body of major city river reaches of the Changjiang River has been generally polluted. In the test, totally 12 types with 308 kinds of organic compounds were detected. The main pollutants were paraffins, PAHs and lipids; and ② micro organic pollutant content in fish bodies was generally higher than that in bottom material which is in turn higher than that in water; and ③ pollution is relatively severe in the river reaches of mid-to-large comprehensive industrial cities with fairly great TAS (Total Ambient Severity) of public health and ecological system.展开更多
为探究大豆基于株高抗旱系数(drought resistance coefficient based on plant height,DCPH)和主茎节数抗旱系数(drought resistance coefficient based on number of main stem nodes,DCNS)的抗性遗传基础,本研究选取由113份大豆品种(...为探究大豆基于株高抗旱系数(drought resistance coefficient based on plant height,DCPH)和主茎节数抗旱系数(drought resistance coefficient based on number of main stem nodes,DCNS)的抗性遗传基础,本研究选取由113份大豆品种(系)组成的自然群体作为研究材料,在全生育期干旱胁迫和正常供水条件下测定了株高和主茎节数,分别计算两种类型的抗旱系数,并利用全基因组关联分析技术(Genome-Wide Association Study,GWAS),挖掘与大豆株高和主茎节数抗旱性相关的基因和位点。结果显示:利用1882531个SNP标记进行GWAS分析,DCPH显著关联的位点全部位于9号染色体上,而DCNS显著关联的位点全部位于6号染色体上。进一步分析确定了DCPH和DCNS的候选基因区间,分别筛选出41个与DCPH相关的候选基因和15个与DCNS相关的候选基因。这些基因可能参与大豆生长发育的调控、激素信号传导、细胞分裂和生长等过程。本研究不仅为深入解析大豆抗旱性的分子机制提供了重要线索,还为培育抗旱性强的大豆品种提供了宝贵的基因资源。展开更多
To discover and identify the influential nodes in any complex network has been an important issue.It is a significant factor in order to control over the network.Through control on a network,any information can be spr...To discover and identify the influential nodes in any complex network has been an important issue.It is a significant factor in order to control over the network.Through control on a network,any information can be spread and stopped in a short span of time.Both targets can be achieved,since network of information can be extended and as well destroyed.So,information spread and community formation have become one of the most crucial issues in the world of SNA(Social Network Analysis).In this work,the complex network of twitter social network has been formalized and results are analyzed.For this purpose,different network metrics have been utilized.Visualization of the network is provided in its original form and then filter out(different percentages)from the network to eliminate the less impacting nodes and edges for better analysis.This network is analyzed according to different centrality measures,like edge-betweenness,betweenness centrality,closeness centrality and eigenvector centrality.Influential nodes are detected and their impact is observed on the network.The communities are analyzed in terms of network coverage considering theMinimum Spanning Tree,shortest path distribution and network diameter.It is found that these are the very effective ways to find influential and central nodes from such big social networks like Facebook,Instagram,Twitter,LinkedIn,etc.展开更多
文摘Objective: The aim was to show that Minimally Invasive total arterial revascularization for left main stem coronary artery disease, via a left anterior Mini thoracotomy using bilateral internal thoracic arteries is feasible, reproducible and safe. Further, there has been no exclusive data or experience with minimally invasive coronary artery bypass grafting in left main stem disease. Methods: From April 2019 to March 2024, 41 patients with left main stem stenosis, left main equivalent disease and unprotected left main with triple vessel disease underwent off pump minimally invasive multivessel coronary artery bypass grafting using either in situ pedicled Bilateral Internal Thoracic arteries or Left and Right Internal Thoracic artery Y composite conduits at three centers. Bilateral Internal Thoracic arteries were harvested under direct vision. All patients had an Intra-Aortic Balloon Pump inserted via the femoral artery prior to induction of anesthesia, to prevent any hemodynamic instability, arrhythmias, and was removed following completion of the procedure in the operating room without any complications. Efficacy and outcomes were evaluated by i) Primary (MACCE)-Major Adverse Cardiac and Cardiovascular events and ii) Secondary outcome measures including total length of stay, return to full physical activity and quality of life. Mean follow-up was 1.4 years (Maximum was 2.5 years). Results: 41 patients with left main stem coronary artery stenosis, underwent total arterial revascularization using bilateral internal thoracic arteries. Left main stem stenosis was present in 29 patients, Unprotected left main stem stenosis with triple vessel disease in 7 and left main equivalence in 5 patients. In this cohort, 29 patients with only left main stem stenosis had 2 grafts each, 7 patients with left main and triple vessel disease had 3 grafts and 5 patients with left main equivalent disease had 2 grafts respectively. The average number of grafts was 2.2. One patient was converted to open sternotomy as an emergency because of hemodynamic instability and myocardial revascularization was done on cardiopulmonary bypass (2.2%). The average hospital stay was 3.7 days. Ejection fraction was 45% ± 5%. There was one mortality (2.2%) but no major morbidity. The average ICU and hospital stay was 24 ± 4 hours and 3.7 days. All patients were free from major adverse cardiac and cerebrovascular events at follow-up. Conclusions: Multivessel total arterial revascularization using left and right internal thoracic arteries, was performed via a left anterior Mini thoracotomy on patients with left main stem disease and showed that it was safe, reproducible and will help extend the armamentarium of the surgeon in minimally invasive Coronary artery bypass grafting. Concomitantly it helped enhance the potential for shorter hospital stay, increased survival, decreased morbidity, and earlier return to full activity. Furthermore, the safety, efficacy, and outcomes of minimally invasive coronary artery bypass grafting in this high-risk group evaluated by primary and secondary outcome measures have been good in this study.
文摘It has become general for surface waters being polluted by micro organic compounds. In order to know the current pollution situation and the properties of micro organic compounds in the Changjiang River, a test was performed on micro organic compounds in the water, bottom material and fish bodies which were sampled from major city river reaches of the Changjiang River. Based on the test result, researchers described and analyzed the sorts, concentration level and distribution features of micro organic compounds. A comprehensive evaluation was conducted by adopting the method of MEG (Multimedia Environmental Goals). The study indicated that ① the water body of major city river reaches of the Changjiang River has been generally polluted. In the test, totally 12 types with 308 kinds of organic compounds were detected. The main pollutants were paraffins, PAHs and lipids; and ② micro organic pollutant content in fish bodies was generally higher than that in bottom material which is in turn higher than that in water; and ③ pollution is relatively severe in the river reaches of mid-to-large comprehensive industrial cities with fairly great TAS (Total Ambient Severity) of public health and ecological system.
文摘为探究大豆基于株高抗旱系数(drought resistance coefficient based on plant height,DCPH)和主茎节数抗旱系数(drought resistance coefficient based on number of main stem nodes,DCNS)的抗性遗传基础,本研究选取由113份大豆品种(系)组成的自然群体作为研究材料,在全生育期干旱胁迫和正常供水条件下测定了株高和主茎节数,分别计算两种类型的抗旱系数,并利用全基因组关联分析技术(Genome-Wide Association Study,GWAS),挖掘与大豆株高和主茎节数抗旱性相关的基因和位点。结果显示:利用1882531个SNP标记进行GWAS分析,DCPH显著关联的位点全部位于9号染色体上,而DCNS显著关联的位点全部位于6号染色体上。进一步分析确定了DCPH和DCNS的候选基因区间,分别筛选出41个与DCPH相关的候选基因和15个与DCNS相关的候选基因。这些基因可能参与大豆生长发育的调控、激素信号传导、细胞分裂和生长等过程。本研究不仅为深入解析大豆抗旱性的分子机制提供了重要线索,还为培育抗旱性强的大豆品种提供了宝贵的基因资源。
文摘To discover and identify the influential nodes in any complex network has been an important issue.It is a significant factor in order to control over the network.Through control on a network,any information can be spread and stopped in a short span of time.Both targets can be achieved,since network of information can be extended and as well destroyed.So,information spread and community formation have become one of the most crucial issues in the world of SNA(Social Network Analysis).In this work,the complex network of twitter social network has been formalized and results are analyzed.For this purpose,different network metrics have been utilized.Visualization of the network is provided in its original form and then filter out(different percentages)from the network to eliminate the less impacting nodes and edges for better analysis.This network is analyzed according to different centrality measures,like edge-betweenness,betweenness centrality,closeness centrality and eigenvector centrality.Influential nodes are detected and their impact is observed on the network.The communities are analyzed in terms of network coverage considering theMinimum Spanning Tree,shortest path distribution and network diameter.It is found that these are the very effective ways to find influential and central nodes from such big social networks like Facebook,Instagram,Twitter,LinkedIn,etc.
