The mafic-ultramafic complexes and associated formationsare wide spread within the Ural folded belt,which is located on the boundary of the East European plate and West Siberian sedimentary basin.Two main
Early Permian mafic-ultramafic complexes in eastern Xinjiang （新疆） are mainly distributed in the Beishan （北山） area, Mid-Tianshan （天山） massif and Jueluotage （觉罗塔塔） belt. Systematic compositional mappin...Early Permian mafic-ultramafic complexes in eastern Xinjiang （新疆） are mainly distributed in the Beishan （北山） area, Mid-Tianshan （天山） massif and Jueluotage （觉罗塔塔） belt. Systematic compositional mapping of olivines from these Early Permian mafic-ultramafic complexes demonstrates that an apparently spatial distribution and heterogeneous partial melting in the mantle source exists from the Beishan area, across the Mid-Tianshan massif, to the Jueluotage belt from the south to the north. This is probably consistent with the spatial evolutional differences and tectonic features of these three belts. The decreasing degree of partial melting, as revealed by decreasing Fo contents of olivines, from south to north and from east to west reflects the southward subduction of the Paleo-Asian Ocean and the south location of the indistinct mantle plume in the Permian. Simultan ously, NiO and Fo-mapping in olivine also indicates that sulfide segregation before olivine crystallization played an important role in Ni-Cu mineralization in the mafic-ultramafic complexes. Olivines with the compositional range of Fo （77-86） and NiO （less than 0.22 wt.%） are more favorable for Ni-Cu sulfide mineralization.展开更多
Numeral Permian mafic-ultramafic complexes occur in the Beishan terrane atthe northeastern margin of the Tarim craton,southwestern Central Asian Orogenic Belt,including the Pobei,Cantoushan,Bijiashan,Hongshishan,Xuanw...Numeral Permian mafic-ultramafic complexes occur in the Beishan terrane atthe northeastern margin of the Tarim craton,southwestern Central Asian Orogenic Belt,including the Pobei,Cantoushan,Bijiashan,Hongshishan,Xuanwoling,Zhongposhan and Luodong etc.,intrusions(Qin et al.,2011;Zhang et al.,2017;Xue et al.,2018).These Beishan mafic-ultramafic complexes are composed of peridotite,pyroxenite.展开更多
Exsolution microstructures in olivine grains from dunite units in a few selected tectonic environments are reported here. They include lamellae of clinopyroxene and clinopyroxene-magnetite intergrowth in the Gaositai ...Exsolution microstructures in olivine grains from dunite units in a few selected tectonic environments are reported here. They include lamellae of clinopyroxene and clinopyroxene-magnetite intergrowth in the Gaositai and Yellow Hill Alaskan-type complexes, clinopyroxene-magnetite intergrowth in the Klzildag ophiolite, and chromite lamellae in the Hongshishan mafic-ultramafic intrusive complex. These lamellae commonly occur as needle- or rod-like features and are oriented in olivine grains. The host olivine grains have Fo contents of 92.5-92.6 in the Gaositai complex, 86.5-90.1 in the Yellow Hill complex, 93.2-93.4 in the Klzlldag ophiolite and 86.9-88.3 in the Hongshishan complex. Clinopyroxene in the rod-like intergrowth exsolved in olivine grains in the Gaositai and Yellow Hill is diopside with similar major element compositions of CaO （23.6-24.3wt%）, SiO2 （52.2-54.0wt%）, A1203 （0.67-2.15wt%）, Cr203 （0.10-0.42wt%） and Na20 （0.14-0.26wt%）. It falls into the compositional field of hydrothermal clinopyroxene and its origin is thus probably related to reaction between dunite and fluids. The enrichment of the fluids in Ca2＋, Fe3＋, Cr3＋ and Na＋, resulted in elevated concentrations of these cations in olivine solid solutions via the reaction. With decreasing temperature, the olivine solid solutions altered to an intergrowth of magnetite and clinopyroxene. The Fe3＋ and Cr3＋ preferentially partitioned into magnetite, while Ca2＋ and Na＋ entered clinopyroxene. Since the studied Alaskan-type complexes and ophiolite formed in a subduction environment, the fluids were probably released from the subducted slab. In contrast, the exsolved chromite in olivine grains from the Hongshishan complex that formed in post-orogenic extension setting can be related to olivine equilibrated with Cr-bearing liquid. Similarly, these lamellae have all been observed in serpentine surrounding olivine grains, indicating genetic relations with serpentinization.展开更多
More than twenty mafic-ultramafic complexes. which host several medium-or large-sized Cu-Ni deposits, occur along the Huangshan-Jingerquan (HJ ) belt in EastXinjiang. Rock types in these complexes are predominated by ...More than twenty mafic-ultramafic complexes. which host several medium-or large-sized Cu-Ni deposits, occur along the Huangshan-Jingerquan (HJ ) belt in EastXinjiang. Rock types in these complexes are predominated by peridotite, pyroxene peri-dotite, olivine pyroxenite, gabbronorite, orthopyroxene gabbro, troctolite, gabbro anddiorite. The ultramafic rocks are relatively Fe-euriched and are characterised by an as-semblage of olivine + orthopyroxene + clinopyroxene + hornblend ±plagioclase withoutobvious metamorphic textures. Chemically these complexes are relatively Fe-enrichedand show a tholeiitic trend of evolution. The complexes in this belt are intruded underthe extensional environment in a Mid-Carboniferous back-arc basin. They call be consid-ered as a new type of mafic-ultramafic complexes in orogenic belts, as designated by thename of the East-Xinjiang-type complexes.展开更多
There are series of Cu-Ni sulfide-bearing mafic-ultramafic intrusions widespread in north JilinProvince,Northeastern China. The intrusions formed in Xing’an-Mongolian Orogenic Belt near to the northeastern margin of ...There are series of Cu-Ni sulfide-bearing mafic-ultramafic intrusions widespread in north JilinProvince,Northeastern China. The intrusions formed in Xing’an-Mongolian Orogenic Belt near to the northeastern margin of North China Craton. The complexes were formed in almost same period according to the zircon U-Pb dating reported recently, which means that the complexes were formed in same tectonic period and belong to one tectonic magmatic event. The rock assemblages are different from the ophiolite type and Yidun type in orogenic belt. The mafic-ultramafic complexes formed in the range from 217 Ma to 232 Ma coeval with A-type granites in the area, which formed bimodal igneous rock assemblage. According to the regional angular unconformities, there were existed the orogenies of Caledonian, Hercynian, Early Indosinian, Late Indosinian and Yanshanian. The Early Indosinian coeval with orogenic I-type granites and sanukitie that suggesting the lithosphere thickening in the extrusion tectonic setting of orogenic processes, however the Late Indosinian coeval with bimodal igneous rock assemblage that suggesting the lithosphere thinning in the extension tectonic setting of post-orogenic processes in the Xing’an-Mongolian Orogenic Belt. Chemical composition of the mafic-ultramafic rocks has the characteristics of high-Mg and low-K tholeiites related with inter-continental post-orogenic tectonic setting. The trace elements indicate their formed in conditions of continental extension belt or initial rift and has the characteristics of revolution from oceanic island arc, volcanic arc of continental margin to continental extended belt. The low initial Sr isotopic ratios and positive εNd(t) values suggest that the initial magma of the complexes come from the parting melting of depleted lithospheric mantle. The depleted ithospheric mantle was new formed supported by zircon Hf isotope in Hongqiling complex. The depleted lithospheric mantle may be caused by the asthenosheric mantle upwelling and underplating in the tectonic setting of extension during the Late Indosinian post-orogenic processes.展开更多
Three copper(Ⅱ),nickel and cadmium(Ⅱ)complexes,namely[Cu_(2)(μ-H2dbda)2(phen)2]·2H_(2)O(1),[Ni(μ-H2dbda)(μ-bpb)(H_(2)O)2]n(2),and[Cd(μ-H2dbda)(μ-bpa)]n(3),have been constructed hydrothermally using H4dbda(...Three copper(Ⅱ),nickel and cadmium(Ⅱ)complexes,namely[Cu_(2)(μ-H2dbda)2(phen)2]·2H_(2)O(1),[Ni(μ-H2dbda)(μ-bpb)(H_(2)O)2]n(2),and[Cd(μ-H2dbda)(μ-bpa)]n(3),have been constructed hydrothermally using H4dbda(4,4'-dihydroxy-[1,1'-biphenyl]-3,3'-dicarboxylic acid),phen(1,10-phenanthroline),bpb(1,4-bis(pyrid-4-yl)benzene),bpa(bis(4-pyridyl)amine),and copper,nickel and cadmium chlorides at 160℃.The products were isolated as stable crystalline solids and were characterized by IR spectra,elemental analyses,thermogravimetric analyses,and singlecrystal X-ray diffraction analyses.Single-crystal X-ray diffraction analyses revealed that three complexes crystallize in the monoclinic P21/n,tetragonal I42d,and orthorhombic P21212 space groups.The complexes exhibit molecular dimers(1)or 2D metal-organic networks(2 and 3).The catalytic performances in the Knoevenagel reaction of these complexes were investigated.Complex 1 exhibits an effective catalytic activity and excellent reusability as a heterogeneous catalyst in the Knoevenagel reaction at room temperature.CCDC:2463800,1;2463801,2;2463802,3.展开更多
Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'...Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.展开更多
Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been construc...Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been constructed hydrothermally at 160℃ using H_(3)tpta([1,1':3',1″-terphenyl]-4,4',5'-tricarboxylic acid),py(pyridine),H_(2)biim(2,2'-biimidazole),dpe(1,2-di(4-pyridyl)ethylene),and zinc,nickel and cadmium chlorides,resulting in the formation of stable crystalline solids which were subsequently analyzed using infrared spectroscopy,element analysis,thermogravimetric analysis,as well as structural analyses conducted via single-crystal X-ray diffraction.The findings from these single-crystal Xray diffraction studies indicate that complexes 1-3 form crystals within the monoclinic system P2_(1)/c space group(1)or triclinic system P1 space group(2 and 3),and possess 1D,0D,and 3D structures,respectively.Complex 1 demonstrated substantial catalytic efficiency and excellent reusability as a heterogeneous catalyst in the reaction of Knoevenagel condensation under ambient temperature conditions.In addition,complex 1 also showcased notable anti-wear performance when used in polyalphaolefin synthetic lubricants.CCDC:2449810,1;2449811,2;2449812,3.展开更多
This paper reports the preparation of three di‑iron complexes containing a thiazole moiety.Esterification of complex[Fe_(2)(CO)_(6)(μ‑SCH_(2)CH(CH_(2)OH)S)](1)with 4‑methylthiazole‑5‑carboxylic acid gave the correspo...This paper reports the preparation of three di‑iron complexes containing a thiazole moiety.Esterification of complex[Fe_(2)(CO)_(6)(μ‑SCH_(2)CH(CH_(2)OH)S)](1)with 4‑methylthiazole‑5‑carboxylic acid gave the corresponding ester[Fe_(2)(CO)_(6)(μ‑tedt)](2),where tedt=SCH_(2)CH(CH_(2)OOC(5‑C_(3)HNSCH_(3)))S.Further reactions of complex 2 with tri(ptolyl)phosphine(tp)or tris(4‑fluorophenyl)phosphine(fp)gave the phosphine‑substituted derivatives[Fe_(2)(CO)_(5)(tp)(μ‑tedt)](3)and[Fe_(2)(CO)_(5)(fp)(μ‑tedt)](4).The structures of the newly prepared complexes were elucidated by elemental analysis,NMR,IR,and X‑ray photoelectron spectroscopy.Moreover,single‑crystal X‑ray diffraction analysis confirmed their molecular structures,showing that they contain a di‑iron core ligated by a bridged dithiolate bearing a thiazole moiety and terminal carbonyls.The electrochemical and electrocatalytic proton reduction were probed by cyclic voltammetry,revealing that three complexes can catalyze the reduction of protons to H_(2) under the electrochemical conditions.For comparison,complex 4 possessed the best efficiency with a turnover frequency of 23.5 s^(-1)at 10 mmol·L^(-1)HOAc concentration.In addition,the fungicidal activity of these complexes was also investigated in this study.CCDC:2477511,2;2477512,3;2477513,4.展开更多
The complexes 1-4 of cyclobutanocucurbit[5]uril(CyB5Q[5])with Na^(+)/K^(+)have been synthesized and characterized by single-crystal X-ray diffraction.The results show that although the inorganic salts are used when th...The complexes 1-4 of cyclobutanocucurbit[5]uril(CyB5Q[5])with Na^(+)/K^(+)have been synthesized and characterized by single-crystal X-ray diffraction.The results show that although the inorganic salts are used when the cations are the same and the anions are different,in complex 1,Na^(+)closes one port of CyB5Q[5]through Na—O seven coordination bonds to form a molecular bowl;in complex 3,Na^(+)completely closes the two ports of CyB5Q[5]to form a molecular capsule with six Na—O coordination bonds;in complexes 2 and 4,the two ports of CyB5Q[5]are completely closed to form K—O coordinated molecular capsules,but the K^(+)of complex 2 is six-coordinated and that of complex 4 is eight-/nine-coordinated.and complex 4 are connected by three oxygen bridges to form a 1D molecular chain.CCDC:2457122,1;2457121,2;2457400,3;2457120,4.展开更多
Charge-transfer complexes(CTCs)have emerged as promising n-type organic thermoelectric(TE)materials due to their inherent high electrical conductivity and tunable transport polarities.In this study,we performed a comp...Charge-transfer complexes(CTCs)have emerged as promising n-type organic thermoelectric(TE)materials due to their inherent high electrical conductivity and tunable transport polarities.In this study,we performed a comprehensive first-principles investigation on the TE properties of nine CTCs comprised of 2,7-dialkyl[1]benzothieno[3,2-b][1]benzothiophenes(CnBTBT,n=4,8,12)as donors and fluorinated derivatives of tetracyanoquinodimethane(F_(m)TCNQ,m=0,2,4)as acceptors,aiming to identify high-performance n-type organic TE materials and elucidate the underlying structure-property relationships.Our calculation results,based on the Boltzmann transport equation and deformation potential theory,reveal that the length of the alkyl side chains and the number of fluorine substitutions significantly impact their electronic structures and TE properties.Notably,the CnBTBT-F_(m)TCNQ CTCs with shorter alkyl chains and more fluorine substitution demonstrate superior n-type characteristics,particularly C4BTBT-F4TCNQ,which achieves an excellent power factor of 671µW cm^(-1) K^(-2) at an optimal charge carrier concentration.Our findings not only clarify the critical role of molecular engineering in CTC-based TE materials but also provide valuable guidance for developing high-efficiency organic TE materials with versatile practical applications.展开更多
A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescenc...A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescence(TADF)properties.All calculations were performed using density functional theory(DFT)and time‑dependent density functional theory(TDDFT).Calculations for electronic structures,frontier molecular orbital characteristics(which determine the efficiency roll‑off effect of the complexes),and photophysical properties were conducted using the Gaussian 09 software package.The calculation of spin‑orbit coupling matrix elements<T|HSOC|S>,which determine the TADF properties of the complexes,was performed using the ORCA software package.The calculation results show that the auxiliary ligand tetraphenylimidodiphosphinate(tpip),a strong electron‑withdrawing group,can mitigate the efficiency roll‑off effect of the complex.Furthermore,TADF is observed in one of the designed complexes,(F_(3)Phppy)_(2)Ir(tpip),where F_(3)Phppy=2‑[4‑(2,4,6‑trifluorophenyl)phenyl]pyridine.展开更多
The SHRIMP zircon U-Pb dating was carried out and yielded 287±5 Ma (MSWD = 0.34) and 274±3 Ma (MSWD = 1.35) for the Kalatongke No. 1 and Huangshan- dong Cu-Ni-bearing mafic-ultramafic complexes. These ages a...The SHRIMP zircon U-Pb dating was carried out and yielded 287±5 Ma (MSWD = 0.34) and 274±3 Ma (MSWD = 1.35) for the Kalatongke No. 1 and Huangshan- dong Cu-Ni-bearing mafic-ultramafic complexes. These ages are much more precise than pre-existing rock-mineral Rb-Sr, Sm-Nd and Re-Os isochron ages for the two complexes and constrain the timing of not only the complexes but also the magmatic Cu-Ni sulfide deposits more reliably. It is neces- sary to carefully reevaluate the previous chronological data for the complexes. The Cu-Ni-bearing mafic-ultramafic com- plexes have the ages similar to those of postcollisional A-type granites in the same area, implying that they could be related to the delamination of lithospheric mantle and upwelling and partial melting of asthenospheric mantle in postcollisional setting. Therefore, the Cu-Ni-bearing mafic-ultramafic com- plexes are a direct indicator of vertical growth of the conti- nental crustal in the Central Asian Orogenic Belt.展开更多
The Beishan area has more than seventy mafic-ultramafic complexes sparsely distributed in the area and is of a big potential in mineral resources related to mafic-ultramafic intrusions. Many mafic-ultramafic intrusion...The Beishan area has more than seventy mafic-ultramafic complexes sparsely distributed in the area and is of a big potential in mineral resources related to mafic-ultramafic intrusions. Many mafic-ultramafic intrusions which are mostly in small sizes have been omitted by previous works. This research takes Huitongshan as the study area, which is a major district for mafic-ultramafic occurrences in Beishan. Advanced spaceborne thermal emission and reflection radiometer（ASTER） data have been processed and interpreted for mapping the mafic-ultramafic complex. ASTER data were processed by different techniques that were selected based on image reflectance and laboratory emissivity spectra. The visible near-infrared（VNIR） and short wave infrared（SWIR） data were transformed using band ratios and minimum noise fraction（MNF）, while the thermal infrared（TIR） data were processed using mafic index（MI） and principal components analysis（PCA）. ASTER band ratios（6/8, 5/4, 2/1） in RGB image and MNF（1, 2, 4） in RGB image were powerful in distinguishing the subtle differences between the various rock units. PCA applied to all five bands of ASTER TIR imagery highlighted marked differences among the mafic rock units and was more effective than the MI in differentiating mafic-ultramafic rocks. Our results were consistent with information derived from local geological maps. Based on the remote sensing results and field inspection, eleven gabbroic intrusions and a pyroxenite occurrence were recognized for the first time. A new geologic map of the Huitongshan area was created by integrating the results of remote sensing, previous geological maps and field inspection. It is concluded that the workflow of ASTER image processing, interpretation and ground inspection has great potential for mafic-ultramafic rocks identifying and relevant mineral targeting in the sparsely vegetated arid region of northwestern China.展开更多
To expand the study on the structures and biological activities of the anthracyclines anticancer drugs and reduce their toxic side effects,the new anthraquinone derivatives,9‑pyridylanthrahydrazone(9‑PAH)and 9,10‑bisp...To expand the study on the structures and biological activities of the anthracyclines anticancer drugs and reduce their toxic side effects,the new anthraquinone derivatives,9‑pyridylanthrahydrazone(9‑PAH)and 9,10‑bispyridylanthrahydrazone(9,10‑PAH)were designed and synthesized.Utilizing 9‑PAH and 9,10‑PAH as promising anticancer ligands,their respective copper complexes,namely[Cu(L1)Cl_(2)]Cl(1)and{[Cu_(4)(μ_(2)‑Cl)_(3)Cl_(4)(9,10‑PAH)_(2)(DMSO)_(2)]Cl_(2)}_(n)(2),were subsequently synthesized,where the new ligand L1 is formed by coupling two 9‑PAH ligands in the coordination reaction.The chemical and crystal structures of 1 and 2 were elucidated by IR,MS,elemental analysis,and single‑crystal X‑ray diffraction.Complex 1 forms a mononuclear structure.L1 coordinates with Cu through its three N atoms,together with two Cl atoms,to form a five‑coordinated square pyramidal geometry.Complex 2 constitutes a polymeric structure,wherein each structural unit centrosymmetrically encompasses two five‑coordinated binuclear copper complexes(Cu1,Cu2)of 9,10‑PAH,with similar square pyramidal geometry.A chlorine atom(Cl_(2)),located at the symmetry center,bridges Cu1 and Cu1A to connect the two binuclear copper structures.Meanwhile,the two five‑coordinated Cu2 atoms symmetrically bridge the adjacent structural units via one coordinated Cl atom,respectively,thus forming a 1D chain‑like polymeric structure.In vitro anticancer activity assessments revealed that 1 and 2 showed significant cytotoxicity even higher than cisplatin.Specifically,the IC_(50)values of 2 against HeLa‑229 and SK‑OV‑3 cancer cell lines were determined to be(5.92±0.32)μmol·L^(-1)and(6.48±0.39)μmol·L^(-1),respectively.2 could also block the proliferation of HeLa‑229 cells in S phase and significantly induce cell apoptosis.In addition,fluorescence quenching competition experiments suggested that 2 might interact with DNA by an intercalative binding mode,offering insights into its underlying anticancer mechanism.CCDC:2388918,1;2388919,2.展开更多
Mikbi intrusion(MI) is a part of the Neoproterozoic Nubian Shield located along the NE-SW trending major fracture zones prevailing southern Eastern Desert of Egypt. In this study, we present for the first time detaile...Mikbi intrusion(MI) is a part of the Neoproterozoic Nubian Shield located along the NE-SW trending major fracture zones prevailing southern Eastern Desert of Egypt. In this study, we present for the first time detailed mineralogical and bulk-rock geochemical data to infer some constraints on the parental magma genesis and to understand the tectonic processes contributed to MI formation. Lithologically, it is composed of fresh peridotite, clinopyroxenite, hornblendite, anorthosite, gabbronorite, pyroxene amphibole gabbro, amphibole gabbro and diorite. All rocks have low Th/La ratios(mostly <0.2) and lack positive Zr and Th anomalies excluding significant crustal contamination. They show very low concentrations of Nb, Ta, Zr and Hf together with sub-chondritic ratios of Nb/Ta(2-15) and Zr/Hf(19-35),suggesting that their mantle source was depleted by earlier melting extraction event. The oxygen fugacity(logfO_2) estimated from diorite biotite is around the nickel-nickel oxide buffer(NNO) indicating crystallization from a relatively oxidized magma. Amphiboles in the studied mafic-ultramafic rocks indicate relative oxygen fugacity(i.e. ΔNNO; nickel-nickel oxide) of 0.28-3 and were in equilibrium mostly with 3.77-8.24 wt.% H_2 O_(melt)(i.e. water content in the melt), consistent with the typical values of subduction-related magmas. Moreover, pressure estimates(0.53-6.79 kbar) indicate polybaric crystallization and suggest that the magma chamber(s) was located at relatively shallow crustal levels. The enrichment in LILE(e.g., Cs, Ba, K and Sr) and the depletion in HFSE(e.g., Th and Nb) relative to primitive mantle are consistent with island arc signature. The olivine, pyroxene and amphibole compositions also reflect arc affinity. These inferences suggest that their primary magma was derived from partial melting of a mantle source that formerly metasomatized in a subduction zone setting. Clinopyroxene and bulkrock data are consistent with orogenic tholeiitic affinity. Consequently, the mineral and bulk-rock chemistry strongly indicate crystallization from hydrous tholeiitic magma. Moreover, their trace element patterns are subparallel indicating that the various rock types possibly result from differentiation of the same primary magma. These petrological, mineralogical and geochemical characteristics show that the MI is a typical Alaskan-type complex.展开更多
Metal complexes hold significant promise in tumor diagnosis and treatment.However,their potential applications in photodynamic therapy(PDT)are hindered by issues such as poor photostability,low yield of reactive oxyge...Metal complexes hold significant promise in tumor diagnosis and treatment.However,their potential applications in photodynamic therapy(PDT)are hindered by issues such as poor photostability,low yield of reactive oxygen species(ROS),and aggregation-induced ROS quenching.To address these challenges,we present a molecular self-assembly strategy utilizing aggregation-induced emission(AIE)conjugates for metal complexes.As a proof of concept,we synthesized a mitochondrial-targeting cyclometalated Ir(Ⅲ)photosensitizer Ir-TPE.This approach significantly enhances the photodynamic effect while mitigating the dark toxicity associated with AIE groups.Ir-TPE readily self-assembles into nanoaggregates in aqueous solution,leading to a significant production of ROS upon light irradiation.Photoirradiated Ir-TPE triggers multiple modes of death by excessively accumulating ROS in the mitochondria,resulting in mitochondrial DNA damage.This damage can lead to ferroptosis and autophagy,two forms of cell death that are highly cytotoxic to cancer cells.The aggregation-enhanced photodynamic effect of Ir-TPE significantly enhances the production of ROS,leading to a more pronounced cytotoxic effect.In vitro and in vivo experiments demonstrate this aggregation-enhanced PDT approach achieves effective in situ tumor eradication.This study not only addresses the limitations of metal complexes in terms of low ROS production due to aggregation but also highlights the potential of this strategy for enhancing ROS production in PDT.展开更多
Intracellular bacteria(ICB),cloaked by the protective barriers of host cells,pose a formidable challenge to selective and efficient eradication.The employment of activatable photosensitizers based antibacterial photod...Intracellular bacteria(ICB),cloaked by the protective barriers of host cells,pose a formidable challenge to selective and efficient eradication.The employment of activatable photosensitizers based antibacterial photodynamic therapy(a PDT)holds significant potential for selective imaging and photo-inactivation of ICB while minimizing side effects on normal cells.Drawing inspiration from the elevated hypochlorous acid(HClO)levels in ICB infected phagocytes,herein we firstly designed and synthesized a series of HCl Oresponsive dinuclear Ru(Ⅱ)complexes(Ru1-Ru3)to achieve such a goal.Initially,the luminescence,^(1)O_(2)generation and a PDT activity of these Ru(Ⅱ)complexes were suppressed due to the quenching effect of the azo group,but were recovered after reaction with HCl O in solutions or within ICB infected phagocytes.The detailed results revealed that Ru1 and Ru3 could not only selectively visualize ICB,but also demonstrated remarkable a PDT activity against ICB,surpassing vancomycin both in vitro and in vivo.展开更多
Two novel lanthanide complexes,[Sm_(2)(BA)_(6)(4-OH-terpy)_(2)]·2H_(2)O·2EtOH(1)and[Pr_(2)(BA)_(6)(4-OH-terpy)_(2)(H_(2)O)_(2)]·HBA·H_(2)O(2),where HBA=benzoic acid,4-OH-terpy=4-hydroxy-2,2'∶6...Two novel lanthanide complexes,[Sm_(2)(BA)_(6)(4-OH-terpy)_(2)]·2H_(2)O·2EtOH(1)and[Pr_(2)(BA)_(6)(4-OH-terpy)_(2)(H_(2)O)_(2)]·HBA·H_(2)O(2),where HBA=benzoic acid,4-OH-terpy=4-hydroxy-2,2'∶6',2″-terpyridine,were successfully synthesized using ultrasonic dissolution and the conventional solution method with two mixed ligands HBA and 4-OH-terpy.During the synthesis,4-OH-terpy was involved in the reaction as a neutral ligand,while HBA,in its deprotonated form(BA-),coordinated with the lanthanide ions as an acidic ligand.The crystal structures of these two complexes were precisely determined by single-crystal X-ray diffraction.Elemental analysis,infrared and Raman spectroscopy,and powder X-ray diffraction techniques were also employed to further explore the physicochemical properties of the two complexes.The single-crystal X-ray diffraction data indicate that,despite their structural differences,both complexes belong to the triclinic crystal system P1 space group.The central lanthanide ions have the same coordination number but exhibit different coordination environments.To comprehensively evaluate the thermal stability of these two complexes,comprehensive tests including thermogravimetric analysis,differential thermogravimetric analysis,differential scanning calorimetry,Fourier transform infrared spectroscopy,and mass spectrometry were conducted.Meanwhile,an in-depth investigation was conducted into the 3D infrared stacked images and mass spectra of the gases emitted from the complexes.In addition,studies of the fluorescence properties of complex1 showed that it exhibited fluorescence emission matching the Sm^(3+)characteristic transition.展开更多
基金supported by the Program of UD RAS (project № 15-18-5-24)
文摘The mafic-ultramafic complexes and associated formationsare wide spread within the Ural folded belt,which is located on the boundary of the East European plate and West Siberian sedimentary basin.Two main
基金supported by the National Natural Science Foundation of China (Nos. 41030424,41173011)the Knowledge Innovation Program of the Chinese Academy of Sciences (No. KZCX2-YW-107)the China Postdoctoral Science Foundation to Benxun Su
文摘Early Permian mafic-ultramafic complexes in eastern Xinjiang （新疆） are mainly distributed in the Beishan （北山） area, Mid-Tianshan （天山） massif and Jueluotage （觉罗塔塔） belt. Systematic compositional mapping of olivines from these Early Permian mafic-ultramafic complexes demonstrates that an apparently spatial distribution and heterogeneous partial melting in the mantle source exists from the Beishan area, across the Mid-Tianshan massif, to the Jueluotage belt from the south to the north. This is probably consistent with the spatial evolutional differences and tectonic features of these three belts. The decreasing degree of partial melting, as revealed by decreasing Fo contents of olivines, from south to north and from east to west reflects the southward subduction of the Paleo-Asian Ocean and the south location of the indistinct mantle plume in the Permian. Simultan ously, NiO and Fo-mapping in olivine also indicates that sulfide segregation before olivine crystallization played an important role in Ni-Cu mineralization in the mafic-ultramafic complexes. Olivines with the compositional range of Fo （77-86） and NiO （less than 0.22 wt.%） are more favorable for Ni-Cu sulfide mineralization.
基金supported financially by the NSFC projects(Grant Nos.U1403291,41802074,41830216,41202044)projects of the China Geological Survey(Grant Nos.1212010811033,12120113096500,12120113094000,DD20160123,DD20160009 and DD20179607)+1 种基金the IGCP 662 projectDDE.
文摘Numeral Permian mafic-ultramafic complexes occur in the Beishan terrane atthe northeastern margin of the Tarim craton,southwestern Central Asian Orogenic Belt,including the Pobei,Cantoushan,Bijiashan,Hongshishan,Xuanwoling,Zhongposhan and Luodong etc.,intrusions(Qin et al.,2011;Zhang et al.,2017;Xue et al.,2018).These Beishan mafic-ultramafic complexes are composed of peridotite,pyroxenite.
基金financially supported by the National Natural Science Foundation of China (Grants 41522203, 41673037 and 41772055)Youth Innovation Promotion Association, Chinese Academy of Sciences (Grant 2017095)
文摘Exsolution microstructures in olivine grains from dunite units in a few selected tectonic environments are reported here. They include lamellae of clinopyroxene and clinopyroxene-magnetite intergrowth in the Gaositai and Yellow Hill Alaskan-type complexes, clinopyroxene-magnetite intergrowth in the Klzildag ophiolite, and chromite lamellae in the Hongshishan mafic-ultramafic intrusive complex. These lamellae commonly occur as needle- or rod-like features and are oriented in olivine grains. The host olivine grains have Fo contents of 92.5-92.6 in the Gaositai complex, 86.5-90.1 in the Yellow Hill complex, 93.2-93.4 in the Klzlldag ophiolite and 86.9-88.3 in the Hongshishan complex. Clinopyroxene in the rod-like intergrowth exsolved in olivine grains in the Gaositai and Yellow Hill is diopside with similar major element compositions of CaO （23.6-24.3wt%）, SiO2 （52.2-54.0wt%）, A1203 （0.67-2.15wt%）, Cr203 （0.10-0.42wt%） and Na20 （0.14-0.26wt%）. It falls into the compositional field of hydrothermal clinopyroxene and its origin is thus probably related to reaction between dunite and fluids. The enrichment of the fluids in Ca2＋, Fe3＋, Cr3＋ and Na＋, resulted in elevated concentrations of these cations in olivine solid solutions via the reaction. With decreasing temperature, the olivine solid solutions altered to an intergrowth of magnetite and clinopyroxene. The Fe3＋ and Cr3＋ preferentially partitioned into magnetite, while Ca2＋ and Na＋ entered clinopyroxene. Since the studied Alaskan-type complexes and ophiolite formed in a subduction environment, the fluids were probably released from the subducted slab. In contrast, the exsolved chromite in olivine grains from the Hongshishan complex that formed in post-orogenic extension setting can be related to olivine equilibrated with Cr-bearing liquid. Similarly, these lamellae have all been observed in serpentine surrounding olivine grains, indicating genetic relations with serpentinization.
文摘More than twenty mafic-ultramafic complexes. which host several medium-or large-sized Cu-Ni deposits, occur along the Huangshan-Jingerquan (HJ ) belt in EastXinjiang. Rock types in these complexes are predominated by peridotite, pyroxene peri-dotite, olivine pyroxenite, gabbronorite, orthopyroxene gabbro, troctolite, gabbro anddiorite. The ultramafic rocks are relatively Fe-euriched and are characterised by an as-semblage of olivine + orthopyroxene + clinopyroxene + hornblend ±plagioclase withoutobvious metamorphic textures. Chemically these complexes are relatively Fe-enrichedand show a tholeiitic trend of evolution. The complexes in this belt are intruded underthe extensional environment in a Mid-Carboniferous back-arc basin. They call be consid-ered as a new type of mafic-ultramafic complexes in orogenic belts, as designated by thename of the East-Xinjiang-type complexes.
文摘There are series of Cu-Ni sulfide-bearing mafic-ultramafic intrusions widespread in north JilinProvince,Northeastern China. The intrusions formed in Xing’an-Mongolian Orogenic Belt near to the northeastern margin of North China Craton. The complexes were formed in almost same period according to the zircon U-Pb dating reported recently, which means that the complexes were formed in same tectonic period and belong to one tectonic magmatic event. The rock assemblages are different from the ophiolite type and Yidun type in orogenic belt. The mafic-ultramafic complexes formed in the range from 217 Ma to 232 Ma coeval with A-type granites in the area, which formed bimodal igneous rock assemblage. According to the regional angular unconformities, there were existed the orogenies of Caledonian, Hercynian, Early Indosinian, Late Indosinian and Yanshanian. The Early Indosinian coeval with orogenic I-type granites and sanukitie that suggesting the lithosphere thickening in the extrusion tectonic setting of orogenic processes, however the Late Indosinian coeval with bimodal igneous rock assemblage that suggesting the lithosphere thinning in the extension tectonic setting of post-orogenic processes in the Xing’an-Mongolian Orogenic Belt. Chemical composition of the mafic-ultramafic rocks has the characteristics of high-Mg and low-K tholeiites related with inter-continental post-orogenic tectonic setting. The trace elements indicate their formed in conditions of continental extension belt or initial rift and has the characteristics of revolution from oceanic island arc, volcanic arc of continental margin to continental extended belt. The low initial Sr isotopic ratios and positive εNd(t) values suggest that the initial magma of the complexes come from the parting melting of depleted lithospheric mantle. The depleted ithospheric mantle was new formed supported by zircon Hf isotope in Hongqiling complex. The depleted lithospheric mantle may be caused by the asthenosheric mantle upwelling and underplating in the tectonic setting of extension during the Late Indosinian post-orogenic processes.
文摘Three copper(Ⅱ),nickel and cadmium(Ⅱ)complexes,namely[Cu_(2)(μ-H2dbda)2(phen)2]·2H_(2)O(1),[Ni(μ-H2dbda)(μ-bpb)(H_(2)O)2]n(2),and[Cd(μ-H2dbda)(μ-bpa)]n(3),have been constructed hydrothermally using H4dbda(4,4'-dihydroxy-[1,1'-biphenyl]-3,3'-dicarboxylic acid),phen(1,10-phenanthroline),bpb(1,4-bis(pyrid-4-yl)benzene),bpa(bis(4-pyridyl)amine),and copper,nickel and cadmium chlorides at 160℃.The products were isolated as stable crystalline solids and were characterized by IR spectra,elemental analyses,thermogravimetric analyses,and singlecrystal X-ray diffraction analyses.Single-crystal X-ray diffraction analyses revealed that three complexes crystallize in the monoclinic P21/n,tetragonal I42d,and orthorhombic P21212 space groups.The complexes exhibit molecular dimers(1)or 2D metal-organic networks(2 and 3).The catalytic performances in the Knoevenagel reaction of these complexes were investigated.Complex 1 exhibits an effective catalytic activity and excellent reusability as a heterogeneous catalyst in the Knoevenagel reaction at room temperature.CCDC:2463800,1;2463801,2;2463802,3.
文摘Six new lanthanide complexes:[Ln(3,4-DEOBA)3(4,4'-DM-2,2'-bipy)]2·2C_(2)H_(5)OH,[Ln=Dy(1),Eu(2),Tb(3),Sm(4),Ho(5),Gd(6);3,4-DEOBA-=3,4-diethoxybenzoate,4,4'-DM-2,2'-bipy=4,4'-dimethyl-2,2'-bipyridine]were successfully synthesized by the volatilization of the solution at room temperature.The crystal structures of six complexes were determined by single-crystal X-ray diffraction technology.The results showed that the complexes all have a binuclear structure,and the structures contain free ethanol molecules.Moreover,the coordination number of the central metal of each structural unit is eight.Adjacent structural units interact with each other through hydrogen bonds and further expand to form 1D chain-like and 2D planar structures.After conducting a systematic study on the luminescence properties of complexes 1-4,their emission and excitation spectra were obtained.Experimental results indicated that the fluorescence lifetimes of complexes 2 and 3 were 0.807 and 0.845 ms,respectively.The emission spectral data of complexes 1-4 were imported into the CIE chromaticity coordinate system,and their corre sponding luminescent regions cover the yellow light,red light,green light,and orange-red light bands,respectively.Within the temperature range of 299.15-1300 K,the thermal decomposition processes of the six complexes were comprehensively analyzed by using TG-DSC/FTIR/MS technology.The hypothesis of the gradual loss of ligand groups during the decomposition process was verified by detecting the escaped gas,3D infrared spectroscopy,and ion fragment information detected by mass spectrometry.The specific decomposition path is as follows:firstly,free ethanol molecules and neutral ligands are removed,and finally,acidic ligands are released;the final product is the corresponding metal oxide.CCDC:2430420,1;2430422,2;2430419,3;2430424,4;2430421,5;2430423,6.
文摘Three zinc(Ⅱ),nickel(Ⅱ),and cadmium(Ⅱ)complexes,namely[Zn(μ-Htpta)(py)_(2)]n(1),[Ni(H_(2)biim)2(H_(2)O)2][Ni(tpta)(H_(2)biim)2(H_(2)O)]2·3H_(2)O(2),and[Cd_(3)(μ4-tpta)2(μ-dpe)_(3)]_(n)(3),have been constructed hydrothermally at 160℃ using H_(3)tpta([1,1':3',1″-terphenyl]-4,4',5'-tricarboxylic acid),py(pyridine),H_(2)biim(2,2'-biimidazole),dpe(1,2-di(4-pyridyl)ethylene),and zinc,nickel and cadmium chlorides,resulting in the formation of stable crystalline solids which were subsequently analyzed using infrared spectroscopy,element analysis,thermogravimetric analysis,as well as structural analyses conducted via single-crystal X-ray diffraction.The findings from these single-crystal Xray diffraction studies indicate that complexes 1-3 form crystals within the monoclinic system P2_(1)/c space group(1)or triclinic system P1 space group(2 and 3),and possess 1D,0D,and 3D structures,respectively.Complex 1 demonstrated substantial catalytic efficiency and excellent reusability as a heterogeneous catalyst in the reaction of Knoevenagel condensation under ambient temperature conditions.In addition,complex 1 also showcased notable anti-wear performance when used in polyalphaolefin synthetic lubricants.CCDC:2449810,1;2449811,2;2449812,3.
文摘This paper reports the preparation of three di‑iron complexes containing a thiazole moiety.Esterification of complex[Fe_(2)(CO)_(6)(μ‑SCH_(2)CH(CH_(2)OH)S)](1)with 4‑methylthiazole‑5‑carboxylic acid gave the corresponding ester[Fe_(2)(CO)_(6)(μ‑tedt)](2),where tedt=SCH_(2)CH(CH_(2)OOC(5‑C_(3)HNSCH_(3)))S.Further reactions of complex 2 with tri(ptolyl)phosphine(tp)or tris(4‑fluorophenyl)phosphine(fp)gave the phosphine‑substituted derivatives[Fe_(2)(CO)_(5)(tp)(μ‑tedt)](3)and[Fe_(2)(CO)_(5)(fp)(μ‑tedt)](4).The structures of the newly prepared complexes were elucidated by elemental analysis,NMR,IR,and X‑ray photoelectron spectroscopy.Moreover,single‑crystal X‑ray diffraction analysis confirmed their molecular structures,showing that they contain a di‑iron core ligated by a bridged dithiolate bearing a thiazole moiety and terminal carbonyls.The electrochemical and electrocatalytic proton reduction were probed by cyclic voltammetry,revealing that three complexes can catalyze the reduction of protons to H_(2) under the electrochemical conditions.For comparison,complex 4 possessed the best efficiency with a turnover frequency of 23.5 s^(-1)at 10 mmol·L^(-1)HOAc concentration.In addition,the fungicidal activity of these complexes was also investigated in this study.CCDC:2477511,2;2477512,3;2477513,4.
文摘The complexes 1-4 of cyclobutanocucurbit[5]uril(CyB5Q[5])with Na^(+)/K^(+)have been synthesized and characterized by single-crystal X-ray diffraction.The results show that although the inorganic salts are used when the cations are the same and the anions are different,in complex 1,Na^(+)closes one port of CyB5Q[5]through Na—O seven coordination bonds to form a molecular bowl;in complex 3,Na^(+)completely closes the two ports of CyB5Q[5]to form a molecular capsule with six Na—O coordination bonds;in complexes 2 and 4,the two ports of CyB5Q[5]are completely closed to form K—O coordinated molecular capsules,but the K^(+)of complex 2 is six-coordinated and that of complex 4 is eight-/nine-coordinated.and complex 4 are connected by three oxygen bridges to form a 1D molecular chain.CCDC:2457122,1;2457121,2;2457400,3;2457120,4.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Science(No.XDB0520000)the National Natural Science Foundation of China(Nos.52273170 and 52394271)the National Key R&D Program of China(No.2022YFA1203200).
文摘Charge-transfer complexes(CTCs)have emerged as promising n-type organic thermoelectric(TE)materials due to their inherent high electrical conductivity and tunable transport polarities.In this study,we performed a comprehensive first-principles investigation on the TE properties of nine CTCs comprised of 2,7-dialkyl[1]benzothieno[3,2-b][1]benzothiophenes(CnBTBT,n=4,8,12)as donors and fluorinated derivatives of tetracyanoquinodimethane(F_(m)TCNQ,m=0,2,4)as acceptors,aiming to identify high-performance n-type organic TE materials and elucidate the underlying structure-property relationships.Our calculation results,based on the Boltzmann transport equation and deformation potential theory,reveal that the length of the alkyl side chains and the number of fluorine substitutions significantly impact their electronic structures and TE properties.Notably,the CnBTBT-F_(m)TCNQ CTCs with shorter alkyl chains and more fluorine substitution demonstrate superior n-type characteristics,particularly C4BTBT-F4TCNQ,which achieves an excellent power factor of 671µW cm^(-1) K^(-2) at an optimal charge carrier concentration.Our findings not only clarify the critical role of molecular engineering in CTC-based TE materials but also provide valuable guidance for developing high-efficiency organic TE materials with versatile practical applications.
文摘A series of blue and blue‑green Ir(Ⅲ)complexes has been investigated theoretically to explore their electronic structures,photophysical properties,efficiency roll‑off effect,and thermal activation delayed fluorescence(TADF)properties.All calculations were performed using density functional theory(DFT)and time‑dependent density functional theory(TDDFT).Calculations for electronic structures,frontier molecular orbital characteristics(which determine the efficiency roll‑off effect of the complexes),and photophysical properties were conducted using the Gaussian 09 software package.The calculation of spin‑orbit coupling matrix elements<T|HSOC|S>,which determine the TADF properties of the complexes,was performed using the ORCA software package.The calculation results show that the auxiliary ligand tetraphenylimidodiphosphinate(tpip),a strong electron‑withdrawing group,can mitigate the efficiency roll‑off effect of the complex.Furthermore,TADF is observed in one of the designed complexes,(F_(3)Phppy)_(2)Ir(tpip),where F_(3)Phppy=2‑[4‑(2,4,6‑trifluorophenyl)phenyl]pyridine.
文摘The SHRIMP zircon U-Pb dating was carried out and yielded 287±5 Ma (MSWD = 0.34) and 274±3 Ma (MSWD = 1.35) for the Kalatongke No. 1 and Huangshan- dong Cu-Ni-bearing mafic-ultramafic complexes. These ages are much more precise than pre-existing rock-mineral Rb-Sr, Sm-Nd and Re-Os isochron ages for the two complexes and constrain the timing of not only the complexes but also the magmatic Cu-Ni sulfide deposits more reliably. It is neces- sary to carefully reevaluate the previous chronological data for the complexes. The Cu-Ni-bearing mafic-ultramafic com- plexes have the ages similar to those of postcollisional A-type granites in the same area, implying that they could be related to the delamination of lithospheric mantle and upwelling and partial melting of asthenospheric mantle in postcollisional setting. Therefore, the Cu-Ni-bearing mafic-ultramafic com- plexes are a direct indicator of vertical growth of the conti- nental crustal in the Central Asian Orogenic Belt.
基金supported by the Special Fund for Basic Scientific Research of Central Colleges (Nos. 2014G1271060, 2013G1271103)Chang’an University, China and the High Resolution Earth Observation Systems of National Science and Technology Major Projects
文摘The Beishan area has more than seventy mafic-ultramafic complexes sparsely distributed in the area and is of a big potential in mineral resources related to mafic-ultramafic intrusions. Many mafic-ultramafic intrusions which are mostly in small sizes have been omitted by previous works. This research takes Huitongshan as the study area, which is a major district for mafic-ultramafic occurrences in Beishan. Advanced spaceborne thermal emission and reflection radiometer（ASTER） data have been processed and interpreted for mapping the mafic-ultramafic complex. ASTER data were processed by different techniques that were selected based on image reflectance and laboratory emissivity spectra. The visible near-infrared（VNIR） and short wave infrared（SWIR） data were transformed using band ratios and minimum noise fraction（MNF）, while the thermal infrared（TIR） data were processed using mafic index（MI） and principal components analysis（PCA）. ASTER band ratios（6/8, 5/4, 2/1） in RGB image and MNF（1, 2, 4） in RGB image were powerful in distinguishing the subtle differences between the various rock units. PCA applied to all five bands of ASTER TIR imagery highlighted marked differences among the mafic rock units and was more effective than the MI in differentiating mafic-ultramafic rocks. Our results were consistent with information derived from local geological maps. Based on the remote sensing results and field inspection, eleven gabbroic intrusions and a pyroxenite occurrence were recognized for the first time. A new geologic map of the Huitongshan area was created by integrating the results of remote sensing, previous geological maps and field inspection. It is concluded that the workflow of ASTER image processing, interpretation and ground inspection has great potential for mafic-ultramafic rocks identifying and relevant mineral targeting in the sparsely vegetated arid region of northwestern China.
文摘To expand the study on the structures and biological activities of the anthracyclines anticancer drugs and reduce their toxic side effects,the new anthraquinone derivatives,9‑pyridylanthrahydrazone(9‑PAH)and 9,10‑bispyridylanthrahydrazone(9,10‑PAH)were designed and synthesized.Utilizing 9‑PAH and 9,10‑PAH as promising anticancer ligands,their respective copper complexes,namely[Cu(L1)Cl_(2)]Cl(1)and{[Cu_(4)(μ_(2)‑Cl)_(3)Cl_(4)(9,10‑PAH)_(2)(DMSO)_(2)]Cl_(2)}_(n)(2),were subsequently synthesized,where the new ligand L1 is formed by coupling two 9‑PAH ligands in the coordination reaction.The chemical and crystal structures of 1 and 2 were elucidated by IR,MS,elemental analysis,and single‑crystal X‑ray diffraction.Complex 1 forms a mononuclear structure.L1 coordinates with Cu through its three N atoms,together with two Cl atoms,to form a five‑coordinated square pyramidal geometry.Complex 2 constitutes a polymeric structure,wherein each structural unit centrosymmetrically encompasses two five‑coordinated binuclear copper complexes(Cu1,Cu2)of 9,10‑PAH,with similar square pyramidal geometry.A chlorine atom(Cl_(2)),located at the symmetry center,bridges Cu1 and Cu1A to connect the two binuclear copper structures.Meanwhile,the two five‑coordinated Cu2 atoms symmetrically bridge the adjacent structural units via one coordinated Cl atom,respectively,thus forming a 1D chain‑like polymeric structure.In vitro anticancer activity assessments revealed that 1 and 2 showed significant cytotoxicity even higher than cisplatin.Specifically,the IC_(50)values of 2 against HeLa‑229 and SK‑OV‑3 cancer cell lines were determined to be(5.92±0.32)μmol·L^(-1)and(6.48±0.39)μmol·L^(-1),respectively.2 could also block the proliferation of HeLa‑229 cells in S phase and significantly induce cell apoptosis.In addition,fluorescence quenching competition experiments suggested that 2 might interact with DNA by an intercalative binding mode,offering insights into its underlying anticancer mechanism.CCDC:2388918,1;2388919,2.
文摘Mikbi intrusion(MI) is a part of the Neoproterozoic Nubian Shield located along the NE-SW trending major fracture zones prevailing southern Eastern Desert of Egypt. In this study, we present for the first time detailed mineralogical and bulk-rock geochemical data to infer some constraints on the parental magma genesis and to understand the tectonic processes contributed to MI formation. Lithologically, it is composed of fresh peridotite, clinopyroxenite, hornblendite, anorthosite, gabbronorite, pyroxene amphibole gabbro, amphibole gabbro and diorite. All rocks have low Th/La ratios(mostly <0.2) and lack positive Zr and Th anomalies excluding significant crustal contamination. They show very low concentrations of Nb, Ta, Zr and Hf together with sub-chondritic ratios of Nb/Ta(2-15) and Zr/Hf(19-35),suggesting that their mantle source was depleted by earlier melting extraction event. The oxygen fugacity(logfO_2) estimated from diorite biotite is around the nickel-nickel oxide buffer(NNO) indicating crystallization from a relatively oxidized magma. Amphiboles in the studied mafic-ultramafic rocks indicate relative oxygen fugacity(i.e. ΔNNO; nickel-nickel oxide) of 0.28-3 and were in equilibrium mostly with 3.77-8.24 wt.% H_2 O_(melt)(i.e. water content in the melt), consistent with the typical values of subduction-related magmas. Moreover, pressure estimates(0.53-6.79 kbar) indicate polybaric crystallization and suggest that the magma chamber(s) was located at relatively shallow crustal levels. The enrichment in LILE(e.g., Cs, Ba, K and Sr) and the depletion in HFSE(e.g., Th and Nb) relative to primitive mantle are consistent with island arc signature. The olivine, pyroxene and amphibole compositions also reflect arc affinity. These inferences suggest that their primary magma was derived from partial melting of a mantle source that formerly metasomatized in a subduction zone setting. Clinopyroxene and bulkrock data are consistent with orogenic tholeiitic affinity. Consequently, the mineral and bulk-rock chemistry strongly indicate crystallization from hydrous tholeiitic magma. Moreover, their trace element patterns are subparallel indicating that the various rock types possibly result from differentiation of the same primary magma. These petrological, mineralogical and geochemical characteristics show that the MI is a typical Alaskan-type complex.
基金support from the National Natural Science Foundation of China(Nos.22277056,21977052)the Distinguished Young Scholars of Jiangsu Province(No.BK20230006)+2 种基金the Natural Science Foundation of Jiangsu Province(Nos.BK20230977,BK20231090)the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province(No.23KJB150020)the Jiangsu Excellent Postdoctoral Program(No.2022ZB758)。
文摘Metal complexes hold significant promise in tumor diagnosis and treatment.However,their potential applications in photodynamic therapy(PDT)are hindered by issues such as poor photostability,low yield of reactive oxygen species(ROS),and aggregation-induced ROS quenching.To address these challenges,we present a molecular self-assembly strategy utilizing aggregation-induced emission(AIE)conjugates for metal complexes.As a proof of concept,we synthesized a mitochondrial-targeting cyclometalated Ir(Ⅲ)photosensitizer Ir-TPE.This approach significantly enhances the photodynamic effect while mitigating the dark toxicity associated with AIE groups.Ir-TPE readily self-assembles into nanoaggregates in aqueous solution,leading to a significant production of ROS upon light irradiation.Photoirradiated Ir-TPE triggers multiple modes of death by excessively accumulating ROS in the mitochondria,resulting in mitochondrial DNA damage.This damage can lead to ferroptosis and autophagy,two forms of cell death that are highly cytotoxic to cancer cells.The aggregation-enhanced photodynamic effect of Ir-TPE significantly enhances the production of ROS,leading to a more pronounced cytotoxic effect.In vitro and in vivo experiments demonstrate this aggregation-enhanced PDT approach achieves effective in situ tumor eradication.This study not only addresses the limitations of metal complexes in terms of low ROS production due to aggregation but also highlights the potential of this strategy for enhancing ROS production in PDT.
基金supported by National Natural Science Foundation of China(No.22371289)。
文摘Intracellular bacteria(ICB),cloaked by the protective barriers of host cells,pose a formidable challenge to selective and efficient eradication.The employment of activatable photosensitizers based antibacterial photodynamic therapy(a PDT)holds significant potential for selective imaging and photo-inactivation of ICB while minimizing side effects on normal cells.Drawing inspiration from the elevated hypochlorous acid(HClO)levels in ICB infected phagocytes,herein we firstly designed and synthesized a series of HCl Oresponsive dinuclear Ru(Ⅱ)complexes(Ru1-Ru3)to achieve such a goal.Initially,the luminescence,^(1)O_(2)generation and a PDT activity of these Ru(Ⅱ)complexes were suppressed due to the quenching effect of the azo group,but were recovered after reaction with HCl O in solutions or within ICB infected phagocytes.The detailed results revealed that Ru1 and Ru3 could not only selectively visualize ICB,but also demonstrated remarkable a PDT activity against ICB,surpassing vancomycin both in vitro and in vivo.
文摘Two novel lanthanide complexes,[Sm_(2)(BA)_(6)(4-OH-terpy)_(2)]·2H_(2)O·2EtOH(1)and[Pr_(2)(BA)_(6)(4-OH-terpy)_(2)(H_(2)O)_(2)]·HBA·H_(2)O(2),where HBA=benzoic acid,4-OH-terpy=4-hydroxy-2,2'∶6',2″-terpyridine,were successfully synthesized using ultrasonic dissolution and the conventional solution method with two mixed ligands HBA and 4-OH-terpy.During the synthesis,4-OH-terpy was involved in the reaction as a neutral ligand,while HBA,in its deprotonated form(BA-),coordinated with the lanthanide ions as an acidic ligand.The crystal structures of these two complexes were precisely determined by single-crystal X-ray diffraction.Elemental analysis,infrared and Raman spectroscopy,and powder X-ray diffraction techniques were also employed to further explore the physicochemical properties of the two complexes.The single-crystal X-ray diffraction data indicate that,despite their structural differences,both complexes belong to the triclinic crystal system P1 space group.The central lanthanide ions have the same coordination number but exhibit different coordination environments.To comprehensively evaluate the thermal stability of these two complexes,comprehensive tests including thermogravimetric analysis,differential thermogravimetric analysis,differential scanning calorimetry,Fourier transform infrared spectroscopy,and mass spectrometry were conducted.Meanwhile,an in-depth investigation was conducted into the 3D infrared stacked images and mass spectra of the gases emitted from the complexes.In addition,studies of the fluorescence properties of complex1 showed that it exhibited fluorescence emission matching the Sm^(3+)characteristic transition.
