目的探讨2型糖尿病患者骨形成指标骨钙素N端中分子片段(molecular fragment of osteocalcin N terminal,N-MID)和骨吸收指标I型胶原羧基端肽交联(β-cross-linked C-telopeptide of type I collagen,β-CTX)与骨密度之间的关系。方法将...目的探讨2型糖尿病患者骨形成指标骨钙素N端中分子片段(molecular fragment of osteocalcin N terminal,N-MID)和骨吸收指标I型胶原羧基端肽交联(β-cross-linked C-telopeptide of type I collagen,β-CTX)与骨密度之间的关系。方法将233例2型糖尿病患者按双能X线检测骨密度(bone mineral density,BMD)的检查结果分为3组,骨量正常组103例,骨量减少组106例,骨质疏松组24例。记录其性别、年龄、糖尿病病程、血压等一般资料,检测甘油三酯(triglyceride,TG)、总胆固醇(cholesterol,TC)、空腹血糖(fasting plasm glucose,FPG)、糖化血红蛋白(glycosylated hemoglobin,HBA_1C)、空腹胰岛素(fasting insulin,FINS)、血钙(blood calcium,Ca)、血磷(phosphate,P)、碱性磷酸酶(alkaline phosphatase,ALP)、甲状旁腺素(parathyroid hormone,PTH)、N-MID、β-CTX等生化指标,并进行组间比较及相关分析。结果年龄(age)在三组间比较有统计学意义(P<0.05);男女构成比、糖尿病病程、SBP、DBP、TC、LDL-C、HDL-C、TG、FPG、GSP、HBA_1C、FINS、C-肽、CRP、HCY、ACR、Ca、P、ALP、血清25(OH)D_3在三组间比较均无统计学意义(P>0.05);β-CTX、N-MID、PTH在三组间比较均有统计学意义(P<0.05);骨量异常与否与年龄、β-CTX、N-MID成正相关关系(P<0.05),与血清25(OH)D_3、PTH均无相关关系(P>0.05);血清25(OH)D_3与PTH成负相关关系(P<0.05),PTH与β-CTX、N-MID成正相关关系(P<0.05),β-CTX与N-MID成正相关关系(P<0.05)。结论 2型糖尿病合并骨质疏松症的研究对象骨形成与骨吸收均增高,处于高骨转换水平,破骨细胞活性增强,骨吸收强于骨形成。测定N-MID、β-CTX的浓度可以了解骨代谢、评估骨转换,对早期诊断骨质疏松症提供重要依据。展开更多
In this study,two-dimensional V2CTx MXene has been prepared by selectively etching Al layers from V2 AlC MAX phase by NaF+HCl etching at 90℃for 72 h and its performance as supercapacitor(SC)electrode were tested usin...In this study,two-dimensional V2CTx MXene has been prepared by selectively etching Al layers from V2 AlC MAX phase by NaF+HCl etching at 90℃for 72 h and its performance as supercapacitor(SC)electrode were tested using simulating seawater as electrolyte.V2CTx MXene-based electrodes shows a good capacitance of 181.1 F/g,which is in accordance with the volumetric specific capacitance of 317.8 F/cm^3,and with 89.1%capacitance retention even after 5000 cycle.Compared with other MXenes,V2CTx have better electrochemical performance as SC electrode.This work provides an innovative strategy to apply V2CTx MXene as SC electrode in safety and effective seawater electrolyte.展开更多
Although MXenes is highly attractive as anode materials of lithium ion batteries,it sets a bottleneck for higher capacity of the V2CTxMXene due to the limited interlayer space and the derived surface terminations.Here...Although MXenes is highly attractive as anode materials of lithium ion batteries,it sets a bottleneck for higher capacity of the V2CTxMXene due to the limited interlayer space and the derived surface terminations.Herein,the cation intercalation and ion-exchange were well employed to achieve a K+and Ca2+intercalated V2CTxMXene.A larger interlayer distance and low F surface terminations were thereof obtained,which accelerates the ion transport and promotes the delicate surface of V2CTx MXene.As a result,a package of enhanced capacity,rate performance and cyclability can be achieved.Furthermore,the ion exchange approach can be extended to other 2 D layered materials,and both the interlayer control and the surface modification will be achieved.展开更多
Herein,a simple yet efficient hydrothermal strategy is developed to in-situ convert multi-layered niobium-based MXene(Nb2 CTx)to hierarchical Nb2 CTx/Nb2O5 composite.In the hybrid,the Nb2O5 nanorods are well dispersed...Herein,a simple yet efficient hydrothermal strategy is developed to in-situ convert multi-layered niobium-based MXene(Nb2 CTx)to hierarchical Nb2 CTx/Nb2O5 composite.In the hybrid,the Nb2O5 nanorods are well dispersed in and/or on the Nb2 CTx.Thanks to the synergetic contributions from the high capacity of Nb2O5 and superb electrical conductivity of the two-dimensional Nb2 CTx itself,the resultant Nb2 CTx/Nb2O5 hybrid exhibits excellent rate behaviors and stable long-term cycling behaviors,when evaluated as anodes for Li-ion batteries.展开更多
Sodium ion batteries and capacitors have demonstrated their potential applications for next-generation low-cost energy storage devices.These devices’s rate ability is determined by the fast sodium ion storage behavio...Sodium ion batteries and capacitors have demonstrated their potential applications for next-generation low-cost energy storage devices.These devices’s rate ability is determined by the fast sodium ion storage behavior in electrode materials.Herein,a defective TiO2@reduced graphene oxide(M-TiO2@rGO)self-supporting foam electrode is constructed via a facile MXene decomposition and graphene oxide self-assembling process.The employment of the MXene parent phase exhibits distinctive advantages,enabling defect engineering,nanoengineering,and fluorine-doped metal oxides.As a result,the M-TiO2@rGO electrode shows a pseudocapacitance-dominated hybrid sodium storage mechanism.The pseudocapacitance-dominated process leads to high capacity,remarkable rate ability,and superior cycling performance.Significantly,an M-TiO2@rGO//Na3 V2(PO4)3 sodium full cell and an M-TiO2@rGO//HPAC sodium ion capacitor are fabricated to demonstrate the promising application of M-TiO2@rGO.The sodium ion battery presents a capacity of 177.1 mAh g-1 at 500 mA g-1 and capacity retention of 74%after 200 cycles.The sodium ion capacitor delivers a maximum energy density of 101.2 Wh kg-1 and a maximum power density of 10,103.7 W kg-1.At 1.0 A g-1,it displays an energy retention of 84.7%after 10,000 cycles.展开更多
文摘目的探讨2型糖尿病患者骨形成指标骨钙素N端中分子片段(molecular fragment of osteocalcin N terminal,N-MID)和骨吸收指标I型胶原羧基端肽交联(β-cross-linked C-telopeptide of type I collagen,β-CTX)与骨密度之间的关系。方法将233例2型糖尿病患者按双能X线检测骨密度(bone mineral density,BMD)的检查结果分为3组,骨量正常组103例,骨量减少组106例,骨质疏松组24例。记录其性别、年龄、糖尿病病程、血压等一般资料,检测甘油三酯(triglyceride,TG)、总胆固醇(cholesterol,TC)、空腹血糖(fasting plasm glucose,FPG)、糖化血红蛋白(glycosylated hemoglobin,HBA_1C)、空腹胰岛素(fasting insulin,FINS)、血钙(blood calcium,Ca)、血磷(phosphate,P)、碱性磷酸酶(alkaline phosphatase,ALP)、甲状旁腺素(parathyroid hormone,PTH)、N-MID、β-CTX等生化指标,并进行组间比较及相关分析。结果年龄(age)在三组间比较有统计学意义(P<0.05);男女构成比、糖尿病病程、SBP、DBP、TC、LDL-C、HDL-C、TG、FPG、GSP、HBA_1C、FINS、C-肽、CRP、HCY、ACR、Ca、P、ALP、血清25(OH)D_3在三组间比较均无统计学意义(P>0.05);β-CTX、N-MID、PTH在三组间比较均有统计学意义(P<0.05);骨量异常与否与年龄、β-CTX、N-MID成正相关关系(P<0.05),与血清25(OH)D_3、PTH均无相关关系(P>0.05);血清25(OH)D_3与PTH成负相关关系(P<0.05),PTH与β-CTX、N-MID成正相关关系(P<0.05),β-CTX与N-MID成正相关关系(P<0.05)。结论 2型糖尿病合并骨质疏松症的研究对象骨形成与骨吸收均增高,处于高骨转换水平,破骨细胞活性增强,骨吸收强于骨形成。测定N-MID、β-CTX的浓度可以了解骨代谢、评估骨转换,对早期诊断骨质疏松症提供重要依据。
基金supported by the National Natural Science Foundation of China(No.51772077)Program for Innovative Research Team(in Science and Technology)in the University of Henan Province(No.19IRTSTHN027)+2 种基金Natural Science Foundation of Henan Province(Nos.182300410228 and 182300410275)the China Postdoctoral Science Foundation(No.2019M652537)Henan Postdoctoral Foundation(No.19030065)。
文摘In this study,two-dimensional V2CTx MXene has been prepared by selectively etching Al layers from V2 AlC MAX phase by NaF+HCl etching at 90℃for 72 h and its performance as supercapacitor(SC)electrode were tested using simulating seawater as electrolyte.V2CTx MXene-based electrodes shows a good capacitance of 181.1 F/g,which is in accordance with the volumetric specific capacitance of 317.8 F/cm^3,and with 89.1%capacitance retention even after 5000 cycle.Compared with other MXenes,V2CTx have better electrochemical performance as SC electrode.This work provides an innovative strategy to apply V2CTx MXene as SC electrode in safety and effective seawater electrolyte.
基金financial support provided by the National Natural Science Foundation of China(No.51932005)Liao Ning Revitalization Talents Program(XLYC1807175)+4 种基金the Joint Research Fund Liaoning Shenyang National Laboratory for Materials Science(SYNL)(20180510047)the Research Fund of SYNL(L2019F38)the Youth Innovation Promotion Association CAS(2015152)the Program for the Development of Science and Technology of Jilin Province(No.20190201309JC)the Project of Development and Reform Commission of Jilin Province(No.2019C042-1)。
文摘Although MXenes is highly attractive as anode materials of lithium ion batteries,it sets a bottleneck for higher capacity of the V2CTxMXene due to the limited interlayer space and the derived surface terminations.Herein,the cation intercalation and ion-exchange were well employed to achieve a K+and Ca2+intercalated V2CTxMXene.A larger interlayer distance and low F surface terminations were thereof obtained,which accelerates the ion transport and promotes the delicate surface of V2CTx MXene.As a result,a package of enhanced capacity,rate performance and cyclability can be achieved.Furthermore,the ion exchange approach can be extended to other 2 D layered materials,and both the interlayer control and the surface modification will be achieved.
基金the financial support from the National Natural Science Foundation of China(Nos.51772127 and 51772131)Taishan Scholars(No.ts201712050)+3 种基金Major Program of Shandong Province Natural Science Foundation(No.ZR2018ZB0317)Natural Science Doctoral Foundation of Shandong Province(No.ZR2019BEM038)Natural Science Doctoral Foundation of the University of Jinan(No.XBS1830)Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of Shandong。
文摘Herein,a simple yet efficient hydrothermal strategy is developed to in-situ convert multi-layered niobium-based MXene(Nb2 CTx)to hierarchical Nb2 CTx/Nb2O5 composite.In the hybrid,the Nb2O5 nanorods are well dispersed in and/or on the Nb2 CTx.Thanks to the synergetic contributions from the high capacity of Nb2O5 and superb electrical conductivity of the two-dimensional Nb2 CTx itself,the resultant Nb2 CTx/Nb2O5 hybrid exhibits excellent rate behaviors and stable long-term cycling behaviors,when evaluated as anodes for Li-ion batteries.
基金supported by the National Natural Science Foundation of China(51702063,51672056)Natural Science Foundation of Heilongjiang(LC2018004)+1 种基金China Postdoctoral Science Foundation(2018M630340,2019T120254)the Fundamental Research Funds for the Central University。
文摘Sodium ion batteries and capacitors have demonstrated their potential applications for next-generation low-cost energy storage devices.These devices’s rate ability is determined by the fast sodium ion storage behavior in electrode materials.Herein,a defective TiO2@reduced graphene oxide(M-TiO2@rGO)self-supporting foam electrode is constructed via a facile MXene decomposition and graphene oxide self-assembling process.The employment of the MXene parent phase exhibits distinctive advantages,enabling defect engineering,nanoengineering,and fluorine-doped metal oxides.As a result,the M-TiO2@rGO electrode shows a pseudocapacitance-dominated hybrid sodium storage mechanism.The pseudocapacitance-dominated process leads to high capacity,remarkable rate ability,and superior cycling performance.Significantly,an M-TiO2@rGO//Na3 V2(PO4)3 sodium full cell and an M-TiO2@rGO//HPAC sodium ion capacitor are fabricated to demonstrate the promising application of M-TiO2@rGO.The sodium ion battery presents a capacity of 177.1 mAh g-1 at 500 mA g-1 and capacity retention of 74%after 200 cycles.The sodium ion capacitor delivers a maximum energy density of 101.2 Wh kg-1 and a maximum power density of 10,103.7 W kg-1.At 1.0 A g-1,it displays an energy retention of 84.7%after 10,000 cycles.
