The research findings on the ground motion and liquefaction potential analyses during the 2018 Great Indonesia Earthquake(M_(w)7.5)are significant and crucial.The earthquake triggered soil-structure damage due to liqu...The research findings on the ground motion and liquefaction potential analyses during the 2018 Great Indonesia Earthquake(M_(w)7.5)are significant and crucial.The earthquake triggered soil-structure damage due to liquefaction.This study,which thoroughly investigated four sites at Palu,was conducted by performing a comprehensive ground motion parameter analysis.The ground motion characteristics were presented and justified,particularly for the most impacted direction.Ground motion predictions were analysed to define the spectral accelerations,and matching spectral accelerations were conducted to produce ground motions for each site.Non-linear seismic ground response analysis based on the hyperbolic model of pressure pressure-dependent was performed to investigate cyclic soil behaviour.The results revealed that ground motion is crucial in significant soil damage,and the earthquake energy could trigger deep liquefaction.As the most significant ground motion,the vertical ground motion is essential in determining deep liquefaction.The discussion on the impact of liquefaction based on the results of the numerical analysis is presented.Significant ground motion with a longer duration could have a substantial impact on deep liquefaction in the study area.These findings depict how the 2018 Indonesia Earthquake(M_(w)7.5)triggered a mega-liquefaction in Palu City.The results could enhance the understanding of the importance of seismic hazard assessment.It is recommended that site investigation and soil improvement should be planned to counteract liquefaction damage before construction.This study also suggests conducting seismic hazard assessments for city development to minimise the potential disaster impact in the study area.展开更多
文摘【目的】早发性肌无力综合征(early onset muscle weakness syndrome,MW)是新近发现的一种荷斯坦牛遗传缺陷,患病犊牛表现为出生后趴卧不起、后肢肌肉萎缩等,其遗传机制与L型钙通道蛋白α1S亚基编码基因CACNA1S的单碱基突变相关。本研究旨在建立该遗传缺陷的分子检测方法,并探究其在国内荷斯坦牛群体中的扩散情况。【方法】基于MW致病位点特异性DNA序列,设计扩增阻滞突变系统-聚合酶链式反应(ARMS-PCR)检测引物,对317份荷斯坦牛冻精和毛囊样本进行MW遗传缺陷基因筛查,通过Sanger测序对ARMS-PCR检测结果进行验证,并利用系谱数据追溯MW突变源头。【结果】ARMS-PCR检出MW携带者21头,携带率为6.62%(21/317),未发现缺陷基因纯合子,提示该突变为隐性纯合致死。Sanger测序与ARMS-PCR所得基因型完全一致,证明该技术具有高度准确性。系谱追溯表明,MW携带者的遗传来源可追溯至1984年出生的荷斯坦公牛Southwind Bell of Bar-Lee。【结论】MW遗传缺陷已在中国荷斯坦牛群体中扩散且携带率较高,建议牧场应尽早开展MW遗传缺陷基因检测和风险评估,采取科学的选种选配措施以减少遗传缺陷导致的经济损失。
基金The World Class Professor(WCP)Program of the Directorate of Resources,Directorate General of Higher Education,Ministry of Education and Culture in 2023 supports this studythe JAPAN-ASEAN Science and Technology Innovation Platform(JASTIP-WP4)+3 种基金the University of Bengkulu's International Collaboration Research Fund(2183/UN30.15/LT/2019)for partial fundingthe C2F Fund for Postdoctoral Fellowship from Chulalongkorn Universitythe Thailand Science Research and Innovation Fund Chulalongkorn University(DISF68210001)the National Research Council of Thailand(N42A670572)。
文摘The research findings on the ground motion and liquefaction potential analyses during the 2018 Great Indonesia Earthquake(M_(w)7.5)are significant and crucial.The earthquake triggered soil-structure damage due to liquefaction.This study,which thoroughly investigated four sites at Palu,was conducted by performing a comprehensive ground motion parameter analysis.The ground motion characteristics were presented and justified,particularly for the most impacted direction.Ground motion predictions were analysed to define the spectral accelerations,and matching spectral accelerations were conducted to produce ground motions for each site.Non-linear seismic ground response analysis based on the hyperbolic model of pressure pressure-dependent was performed to investigate cyclic soil behaviour.The results revealed that ground motion is crucial in significant soil damage,and the earthquake energy could trigger deep liquefaction.As the most significant ground motion,the vertical ground motion is essential in determining deep liquefaction.The discussion on the impact of liquefaction based on the results of the numerical analysis is presented.Significant ground motion with a longer duration could have a substantial impact on deep liquefaction in the study area.These findings depict how the 2018 Indonesia Earthquake(M_(w)7.5)triggered a mega-liquefaction in Palu City.The results could enhance the understanding of the importance of seismic hazard assessment.It is recommended that site investigation and soil improvement should be planned to counteract liquefaction damage before construction.This study also suggests conducting seismic hazard assessments for city development to minimise the potential disaster impact in the study area.