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AI-driven integration of multi-omics and multimodal data for precision medicine
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作者 Heng-Rui Liu 《Medical Data Mining》 2026年第1期1-2,共2页
High-throughput transcriptomics has evolved from bulk RNA-seq to single-cell and spatial profiling,yet its clinical translation still depends on effective integration across diverse omics and data modalities.Emerging ... High-throughput transcriptomics has evolved from bulk RNA-seq to single-cell and spatial profiling,yet its clinical translation still depends on effective integration across diverse omics and data modalities.Emerging foundation models and multimodal learning frameworks are enabling scalable and transferable representations of cellular states,while advances in interpretability and real-world data integration are bridging the gap between discovery and clinical application.This paper outlines a concise roadmap for AI-driven,transcriptome-centered multi-omics integration in precision medicine(Figure 1). 展开更多
关键词 high throughput transcriptomics multi omics single cell multimodal learning frameworks foundation models omics data modalitiesemerging ai driven precision medicine
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Intelligent integration and advancement of multi-organ-on-a-chip
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作者 Chen-Xi Song Lu Huang 《Biomedical Engineering Communications》 2026年第1期1-3,共3页
Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technol... Multi-organ-on-a-chip(MOOC)technology represents a pivotal direction in the organ-on-a-chip field,seeking to emulate the complex interactions of multiple human organs in vitro through microfluidic systems.This technology overcomes the limitations of traditional single-organ models,providing a novel platform for investigating complex disease mechanisms and evaluating drug efficacy and toxicity.Although it demonstrates broad application prospects,its development still faces critical bottlenecks,including inadequate physiological coupling between organs,short functional maintenance durations,and limited real-time monitoring capabilities.Contemporary research is advancing along three key directions,including functional coupling,sensor integration,and full-process automation systems,to propel the technology toward enhanced levels of physiological relevance and predictive accuracy. 展开更多
关键词 investigating complex disease mechanisms emulate complex interactions multiple human organs vitro sensor integration intelligent integration predictive accuracy physiological coupling multi organ chip microfluidic systemsthis
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DFCOA:Distributed Formation Control and Obstacle Avoidance for Multi-UGV Systems
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作者 Md.Faishal Rahaman Xueyuan Li +3 位作者 Muhammad Amjad Ibrahim Gasimove Md.Shariful Islam S.M.Abul Bashar 《Computer Modeling in Engineering & Sciences》 2026年第2期922-954,共33页
Researchers are increasingly focused on enabling groups of multiple unmanned vehicles to operate cohesively in complex,real-world environments,where coordinated formation control and obstacle avoidance are essential f... Researchers are increasingly focused on enabling groups of multiple unmanned vehicles to operate cohesively in complex,real-world environments,where coordinated formation control and obstacle avoidance are essential for executing sophisticated collective tasks.This paper presents a Distributed Formation Control and Obstacle Avoidance(DFCOA)framework for multi-unmanned ground vehicles(UGV).DFCOA integrates a virtual leader structure for global guidance,an improved A^(*)path planning algorithm with an advanced cost function for efficient path planning,and a repulsive-force-based improved vector field histogram star(VFH^(*))technique for collision avoidance.The virtual leader generates a reference trajectory while enabling distributed execution;the improved A^(*)algorithm reduces planning time and number of nodes to determine the shortest path from the starting position to the goal;and the improved VFH^(*)uses 2D LiDAR data with inter-agent repulsive force to simultaneously avoid collision with obstacles and maintain safe inter-vehicle distances.The formation stability of the proposed DFCOA reaches 95.8%and 94.6%in two scenarios,with root mean square(RMS)centroid errors of 0.9516 and 1.0008 m,respectively.Velocity tracking is precise(velocity centroid error RMS of 0.2699 and 0.1700 m/s),and linear velocities closely match the desired 0.3 m/s.Safety metrics showed average collision risks of 0.7773 and 0.5143,with minimum inter-vehicle distances of 0.4702 and 0.8763 m,confirming collision-free navigation of four UGVs.DFCOA outperforms conventional methods in formation stability,path efficiency,and scalability,proving its suitability for decentralized multi-UGV applications. 展开更多
关键词 Formation control obstacle avoidance virtual leader path planning multi UGV collaboration
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Erratum to:a multi-modal smart chest patch for real-time cardiopulmonary monitoring and anomaly detection(vol 68,issue 12,page 4422,2025)
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作者 Shirong Qiu Tianxiao Xiao +5 位作者 Yihao Li Xiong Yu Shun Wu Yiming Zhang Yuanjing Lin Ni Zhao 《Science China Materials》 2026年第3期1814-1814,共1页
In the version of the article originally published in the volume 68,issue 12,2025 of Sci China Mater(pages 4413-4422,https://doi.org/10.1007/s40843-025-3667-7),the Chinese name of the co-first author(肖天孝)was incorr... In the version of the article originally published in the volume 68,issue 12,2025 of Sci China Mater(pages 4413-4422,https://doi.org/10.1007/s40843-025-3667-7),the Chinese name of the co-first author(肖天孝)was incorrect.The corrected Chinese name is:肖天笑. 展开更多
关键词 cardiopulmonary monitoring anomaly detection multi modal monitoring smart chest patch
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Face-Pedestrian Joint Feature Modeling with Cross-Category Dynamic Matching for Occlusion-Robust Multi-Object Tracking
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作者 Qin Hu Hongshan Kong 《Computers, Materials & Continua》 2026年第1期870-900,共31页
To address the issues of frequent identity switches(IDs)and degraded identification accuracy in multi object tracking(MOT)under complex occlusion scenarios,this study proposes an occlusion-robust tracking framework ba... To address the issues of frequent identity switches(IDs)and degraded identification accuracy in multi object tracking(MOT)under complex occlusion scenarios,this study proposes an occlusion-robust tracking framework based on face-pedestrian joint feature modeling.By constructing a joint tracking model centered on“intra-class independent tracking+cross-category dynamic binding”,designing a multi-modal matching metric with spatio-temporal and appearance constraints,and innovatively introducing a cross-category feature mutual verification mechanism and a dual matching strategy,this work effectively resolves performance degradation in traditional single-category tracking methods caused by short-term occlusion,cross-camera tracking,and crowded environments.Experiments on the Chokepoint_Face_Pedestrian_Track test set demonstrate that in complex scenes,the proposed method improves Face-Pedestrian Matching F1 area under the curve(F1 AUC)by approximately 4 to 43 percentage points compared to several traditional methods.The joint tracking model achieves overall performance metrics of IDF1:85.1825%and MOTA:86.5956%,representing improvements of 0.91 and 0.06 percentage points,respectively,over the baseline model.Ablation studies confirm the effectiveness of key modules such as the Intersection over Area(IoA)/Intersection over Union(IoU)joint metric and dynamic threshold adjustment,validating the significant role of the cross-category identity matching mechanism in enhancing tracking stability.Our_model shows a 16.7%frame per second(FPS)drop vs.fairness of detection and re-identification in multiple object tracking(FairMOT),with its cross-category binding module adding aboute 10%overhead,yet maintains near-real-time performance for essential face-pedestrian tracking at small resolutions. 展开更多
关键词 Cross-category dynamic binding joint feature modeling face-pedestrian association multi object tracking occlusion robustness
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Integrated multi-omics dissects receptor-mediated phytomelatonin signaling
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作者 Ying Liu Shirui Jing +5 位作者 Yuhao Zheng Qiuyu He Chengcheng Shen Junxin Guo Yangdong Guo Na Zhang 《Horticultural Plant Journal》 2026年第2期485-488,共4页
Phytomelatonin,an emerging plant hormone,plays vital roles in plant growth,development,and stress adaptation(Arnao et al.,2022;Ullah et al.,2024).It acts both as a direct antioxidant and a signaling molecule,engaging ... Phytomelatonin,an emerging plant hormone,plays vital roles in plant growth,development,and stress adaptation(Arnao et al.,2022;Ullah et al.,2024).It acts both as a direct antioxidant and a signaling molecule,engaging complex networks and interacting with other phytohormones(Liu et al.,2022;Khan et al.,2023).Although phytomelatonin receptors(PMTRs)have been identified in many plants(Wei et al.,2018;Wang et al.,2022;Liu et al.,2025),the downstream signaling mechanisms,particularly receptor-mediated protein modifications and transcriptional regulation,remain poorly characterized. 展开更多
关键词 phytomelatonin receptors pmtrs transcriptional regulation signaling moleculeengaging complex networks integrated multi omics PHYTOHORMONES protein modifications plant hormoneplays phytomelatonin signaling
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Multi-objective ANN-driven genetic algorithm optimization of energy efficiency measures in an NZEB multi-family house building in Greece
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《建筑节能(中英文)》 2026年第2期62-62,共1页
The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measu... The goal of the present work is to demonstrate the potential of Artificial Neural Network(ANN)-driven Genetic Algorithm(GA)methods for energy efficiency and economic performance optimization of energy efficiency measures in a multi-family house building in Greece.The energy efficiency measures include different heating/cooling systems(such as low-temperature and high-temperature heat pumps,natural gas boilers,split units),building envelope components for floor,walls,roof and windows of variable heat transfer coefficients,the installation of solar thermal collectors and PVs.The calculations of the building loads and investment and operating and maintenance costs of the measures are based on the methodology defined in Directive 2010/31/EU,while economic assumptions are based on EN 15459-1 standard.Typically,multi-objective optimization of energy efficiency measures often requires the simulation of very large numbers of cases involving numerous possible combinations,resulting in intense computational load.The results of the study indicate that ANN-driven GA methods can be used as an alternative,valuable tool for reliably predicting the optimal measures which minimize primary energy consumption and life cycle cost of the building with greatly reduced computational requirements.Through GA methods,the computational time needed for obtaining the optimal solutions is reduced by 96.4%-96.8%. 展开更多
关键词 energy efficiency measures gas boilerssplit units building envelope components energy efficiency economic performance artificial neural network ann driven multi objective optimization economic performance optimization ANN driven GA methods
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基于化工过程事故知识谱图-多头时间注意力图网络(CPAKG-MultiTGAT)的化工过程事故情景推演模型
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作者 郑琛 陈国华 +1 位作者 赵远飞 杨运锋 《化工进展》 北大核心 2026年第2期1243-1254,共12页
针对化工园区事故演化过程复杂多变的特征及传统推演方法时空特征融合不足的问题,本文提出了基于CPAKG-MultiTGAT的化工过程事故情景推演模型。通过解析485起化工事故案例,构建涵盖5类本体、74种情景节点的化工过程事故知识谱图(chemica... 针对化工园区事故演化过程复杂多变的特征及传统推演方法时空特征融合不足的问题,本文提出了基于CPAKG-MultiTGAT的化工过程事故情景推演模型。通过解析485起化工事故案例,构建涵盖5类本体、74种情景节点的化工过程事故知识谱图(chemical process accident knowledge graph,CPAKG),实现事故要素的时空关联建模。创新设计的多头时间注意力图网络(multi-head temporal graph attention network,MultiTGAT)融合时间戳编码与图结构特征,以CPAKG的时空拓扑为输入,动态解析节点间跨时空的耦合关系,实现事故情景演化链路预测。实验表明,在自建数据集上,模型AUC与AP值分别达0.865和0.858,较GCN、TGAT-NoTime等基准模型有显著提升,能够有效推演事故演化链路。本文研究成果为化工为事故情景推演提供了可解释的数字化工具,推动事故分析从经验驱动向“数据-知识”融合转型,对提升事故防控能力具有重要的工程应用价值。 展开更多
关键词 化工园区 化工过程事故 情景推演 知识谱图 多头时间注意力图网络
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Role of Multi-Electron and Multi-Orbital Effects in High-Order Harmonic Generation of Benzonitrile Molecules
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作者 Man Xing Jun Wang +1 位作者 Xi Zhao Shushan Zhou 《Chinese Physics Letters》 2025年第4期43-49,共7页
Multi-electron and multi-orbital effects play a crucial role in the interaction of strong laser fields with complex molecules.Here,multi-electron effects encompass not only electron-electron Coulomb interactions and e... Multi-electron and multi-orbital effects play a crucial role in the interaction of strong laser fields with complex molecules.Here,multi-electron effects encompass not only electron-electron Coulomb interactions and exchangecorrelation effects but also the interference between the dynamics of different electron wave packets. 展开更多
关键词 electron wave packets multi electron effects multi orbital effects high order harmonic generation benzonitrile molecules exchangecorrelation effects complex moleculesheremulti electron interference dynamics
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“大数据、大模型、大计算”全新范式与舆情精准研判:理论和Multi-Agent实证两个向度的探索 被引量:2
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作者 丁晓蔚 戚庆燕 刘梓航 《传媒观察》 2025年第2期28-42,共15页
本文探讨了“大数据、大模型、大计算”全新范式在舆情精准研判中的相关理论和应用实证。理论部分论述了该范式的概念和所涉关系,分析了其与Multi-Agent多智能体系统之间的联系。实证部分基于此范式在舆情研判中的应用案例,提出Multi-Ag... 本文探讨了“大数据、大模型、大计算”全新范式在舆情精准研判中的相关理论和应用实证。理论部分论述了该范式的概念和所涉关系,分析了其与Multi-Agent多智能体系统之间的联系。实证部分基于此范式在舆情研判中的应用案例,提出Multi-Agent多智能体协作驱动的舆情分析框架,构建全新的舆情研判流程,能有效应对动态变化的舆情环境。采用Multi-Agent对热点事件是否上热搜进行预测和检验,并与传统大模型和BERT模型进行对比分析。研究表明:Multi-Agent在应对涉及公众情感共鸣和社会性广泛事件时具有显著优势,能通过多角度的综合评估提升预测精度和鲁棒性。通过实证研究验证了Multi-Agent在舆情监测中的重要价值,为未来舆情精准研判提供了新的技术路径。 展开更多
关键词 “大数据、大模型、大计算”全新范式 multi-Agent多智能体系统 舆情精准研判
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Multi-Scale Feature Fusion and Advanced Representation Learning for Multi Label Image Classification
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作者 Naikang Zhong Xiao Lin +1 位作者 Wen Du Jin Shi 《Computers, Materials & Continua》 2025年第3期5285-5306,共22页
Multi-label image classification is a challenging task due to the diverse sizes and complex backgrounds of objects in images.Obtaining class-specific precise representations at different scales is a key aspect of feat... Multi-label image classification is a challenging task due to the diverse sizes and complex backgrounds of objects in images.Obtaining class-specific precise representations at different scales is a key aspect of feature representation.However,existing methods often rely on the single-scale deep feature,neglecting shallow and deeper layer features,which poses challenges when predicting objects of varying scales within the same image.Although some studies have explored multi-scale features,they rarely address the flow of information between scales or efficiently obtain class-specific precise representations for features at different scales.To address these issues,we propose a two-stage,three-branch Transformer-based framework.The first stage incorporates multi-scale image feature extraction and hierarchical scale attention.This design enables the model to consider objects at various scales while enhancing the flow of information across different feature scales,improving the model’s generalization to diverse object scales.The second stage includes a global feature enhancement module and a region selection module.The global feature enhancement module strengthens interconnections between different image regions,mitigating the issue of incomplete represen-tations,while the region selection module models the cross-modal relationships between image features and labels.Together,these components enable the efficient acquisition of class-specific precise feature representations.Extensive experiments on public datasets,including COCO2014,VOC2007,and VOC2012,demonstrate the effectiveness of our proposed method.Our approach achieves consistent performance gains of 0.3%,0.4%,and 0.2%over state-of-the-art methods on the three datasets,respectively.These results validate the reliability and superiority of our approach for multi-label image classification. 展开更多
关键词 Image classification multi-LABEL multi scale attention mechanisms feature fusion
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Low-light image enhancement based on multi-illumination estimation and multi-scale fusion
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作者 ZHANG Xin'ai GAO Jing +1 位作者 NIE Kaiming LUO Tao 《Optoelectronics Letters》 2025年第6期362-369,共8页
To improve image quality under low illumination conditions,a novel low-light image enhancement method is proposed in this paper based on multi-illumination estimation and multi-scale fusion(MIMS).Firstly,the illuminat... To improve image quality under low illumination conditions,a novel low-light image enhancement method is proposed in this paper based on multi-illumination estimation and multi-scale fusion(MIMS).Firstly,the illumination is processed by contrast-limited adaptive histogram equalization(CLAHE),adaptive complementary gamma function(ACG),and adaptive detail preserving S-curve(ADPS),respectively,to obtain three components.Then,the fusion-relevant features,exposure,and color contrast are selected as the weight maps.Subsequently,these components and weight maps are fused through multi-scale to generate enhanced illumination.Finally,the enhanced images are obtained by multiplying the enhanced illumination and reflectance.Compared with existing approaches,this proposed method achieves an average increase of 0.81%and 2.89%in the structural similarity index measurement(SSIM)and peak signal-to-noise ratio(PSNR),and a decrease of 6.17%and 32.61%in the natural image quality evaluator(NIQE)and gradient magnitude similarity deviation(GMSD),respectively. 展开更多
关键词 adaptive detail preserving s curve contrast limited adaptive histogram equalization adaptive complementary gamma function low light image enhancement equalization clahe adaptive complementary gamma function acg multi scale fusion weight maps multi illumination estimation
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Multi-brand strategy fuels Luolai's 45.97% gross margin in Q1
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作者 Qiu Shuchen 《China Textile》 2025年第3期34-37,共4页
Recently,Luolai Group released its Q12025 quarterly report.As a leading Chinese home textile enterprise listed on the Shenzhen Stock Exchange in 2009,the company covers the research,design,production,and sales of home... Recently,Luolai Group released its Q12025 quarterly report.As a leading Chinese home textile enterprise listed on the Shenzhen Stock Exchange in 2009,the company covers the research,design,production,and sales of home textile products,and has multiple brands covering different consumer markets.It has expanded its online and offline comprehensive multichannel sales system and is committed to creating a win-win home furnishings and textile industry ecosystem. 展开更多
关键词 multichannel sales ECOSYSTEM home furnishings gross margin home textile multi brand strategy quarterly report
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Multi-chip multi-phase DC−DC converters for AI power:a ring,a chain,or a net,independent or master-slave?
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作者 Yan Lu Zhiguo Tong +3 位作者 Jiacheng Yang Zhewen Yu Mo Huang Xiangyu Mao 《Journal of Semiconductors》 2025年第7期2-4,共3页
Motivation.As artificial intelligence(AI)workloads escalate exponentially,ultra-thin,high-efficiency voltage regulator modules(VRMs)with exceptional power density become essential for backside-mounted configurations[1... Motivation.As artificial intelligence(AI)workloads escalate exponentially,ultra-thin,high-efficiency voltage regulator modules(VRMs)with exceptional power density become essential for backside-mounted configurations[1].Thus,highdensity multiphase DC−DC converters are pivotal for implementing vertical power delivery(VPD)architectures in XPU platforms.Strategically positioning these converters beneath processors and maximizing spatial utilization enables core rail currents exceeding 2 kA while significantly reducing the power distribution network(PDN)losses compared to conventional solutions.The VPD configuration elevates system-level energy efficiency with>100 W power saving per processor,yielding megawatt-scale savings in a datacenter that uses~100000 processors.The synergy of 48 V power conversion architectures and advanced packaging techniques enables the industry’s commitment to balancing computational demands with CO_(2)emission reduction and environmental sustainability. 展开更多
关键词 maximizing spatial utilization vertical power delivery vpd architectures multi chip AI power ring topology xpu platformsstrategically multiphase dc dc converters core rail currents
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Distributed Byzantine-Resilient Learning of Multi-UAV Systems via Filter-Based Centerpoint Aggregation Rules
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作者 Yukang Cui Linzhen Cheng +1 位作者 Michael Basin Zongze Wu 《IEEE/CAA Journal of Automatica Sinica》 2025年第5期1056-1058,共3页
Dear Editor,Through distributed machine learning,multi-UAV systems can achieve global optimization goals without a centralized server,such as optimal target tracking,by leveraging local calculation and communication w... Dear Editor,Through distributed machine learning,multi-UAV systems can achieve global optimization goals without a centralized server,such as optimal target tracking,by leveraging local calculation and communication with neighbors.In this work,we implement the stochastic gradient descent algorithm(SGD)distributedly to optimize tracking errors based on local state and aggregation of the neighbors'estimation.However,Byzantine agents can mislead neighbors,causing deviations from optimal tracking.We prove that the swarm achieves resilient convergence if aggregated results lie within the normal neighbors'convex hull,which can be guaranteed by the introduced centerpoint-based aggregation rule.In the given simulated scenarios,distributed learning using average,geometric median(GM),and coordinate-wise median(CM)based aggregation rules fail to track the target.Compared to solely using the centerpoint aggregation method,our approach,which combines a pre-filter with the centroid aggregation rule,significantly enhances resilience against Byzantine attacks,achieving faster convergence and smaller tracking errors. 展开更多
关键词 global optimization goals multi UAV systems filter based centerpoint aggregation distributed learning optimal target trackingby stochastic gradient descent algorithm sgd distributedly optimize tracking distributed machine learningmulti uav
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