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人胚肺二倍体细胞系MU-L2与MRC-5的生物学特性比较
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作者 杨雅雯 程玮 +5 位作者 靳莉武 张震宇 杨迪 王家敏 陈建国 乔自林 《中国生物制品学杂志》 2025年第9期1043-1048,1055,共7页
目的 对人胚肺细胞系MU-L2、转染SV40-LT基因的MU-L2细胞系MU-SVL2与国际上已建立的人胚肺细胞系MRC-5的生物学特性进行比较,以期将MU-L2细胞系应用于生物医学研究及疫苗生产。方法 采用含10%NBS的MEM培养基培养MU-L2、MU-SVL2、MRC-5细... 目的 对人胚肺细胞系MU-L2、转染SV40-LT基因的MU-L2细胞系MU-SVL2与国际上已建立的人胚肺细胞系MRC-5的生物学特性进行比较,以期将MU-L2细胞系应用于生物医学研究及疫苗生产。方法 采用含10%NBS的MEM培养基培养MU-L2、MU-SVL2、MRC-5细胞,并按《中国药典》三部(2020版)的要求进行传代。镜下观察3种细胞的生长特性,CCK-8法检测细胞的增殖能力,qPCR法检测相对端粒长度,软琼脂克隆形成试验分析细胞成瘤性,吉姆萨染色核型分析法检测染色体的稳定情况,并进行比较。结果 培养72 h后,3种细胞均长成致密单层,细胞呈现典型的漩涡状排列形态,生长状态良好;MU-L2、MU-SVL2细胞在培养3~6 d时增殖速度显著高于MRC-5细胞(F=1.893,P<0.05);随着代次的增加,相对端粒长度随之缩短,且MU-L2、MU-SVL2细胞相对端粒长度均长于相近代次的MRC-5细胞;3种细胞均未见细胞集落形成,且均属于正常人二倍体核型。结论 MU-L2及MU-SVL2细胞增殖能力强、端粒稳定性更佳、无成瘤性且染色体稳定,有望应用于生物医学研究和疫苗生产。 展开更多
关键词 人胚肺二倍体细胞 mu-L2细胞 mu-SVL2细胞 MRC-5细胞 生物学特性
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基于DTM的突发事件舆情演化:以东航MU5735事件为例
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作者 水晶晶 肖荣坤 +1 位作者 周世达 李诗轩 《武汉理工大学学报(信息与管理工程版)》 2025年第5期581-588,共8页
突发事件网络舆情监管是国家应急管理体系的重要组成部分,揭示网络舆情的动态演化规律,对完善舆情响应机制、提升政府治理效能具有重要意义。以“东航MU5735航班坠毁事件”为研究对象,采用动态主题模型(DTM)构建事件全周期主题演化模型... 突发事件网络舆情监管是国家应急管理体系的重要组成部分,揭示网络舆情的动态演化规律,对完善舆情响应机制、提升政府治理效能具有重要意义。以“东航MU5735航班坠毁事件”为研究对象,采用动态主题模型(DTM)构建事件全周期主题演化模型,对舆情阶段划分、主题热度识别、语义结构聚类进行系统分析,探讨突发事件舆情主题阶段性演化特征、核心议题结构与语义网络演化机制。结果表明:该事件网络舆情演化呈现“酝酿-爆发-扩散-衰退”四阶段生命周期特征,演化趋势由事实确认向制度反思递进;舆情话题结构呈长尾分布,关键词共现结构具有明显的语义凝聚性。 展开更多
关键词 动态主题模型(DTM) 网络舆情 舆情生命周期 主题演化 东航mu5735
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基于MU序列标注的古籍命名实体识别研究
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作者 许乾坤 王东波 +1 位作者 刘禹彤 黄水清 《情报学报》 北大核心 2025年第6期736-747,共12页
命名实体识别任务是自然语言处理中众多下游任务的重要基础步骤。古籍作为中华文明的载体,不仅蕴含着丰富的文化遗产,更是汲取历史智慧、启迪未来的重要源泉。提高古籍文本中实体识别的准确性,有助于推动古籍文本结构化、知识体系化,助... 命名实体识别任务是自然语言处理中众多下游任务的重要基础步骤。古籍作为中华文明的载体,不仅蕴含着丰富的文化遗产,更是汲取历史智慧、启迪未来的重要源泉。提高古籍文本中实体识别的准确性,有助于推动古籍文本结构化、知识体系化,助力古籍资源的智能利用和开发。首先,选取本课题组精加工的二十四史古籍作为原始数据集,使用GujiBERT_FAN预训练模型对Sequence Labeling、Sequence Labeling_CRF、Span-level Prediction方法进行微调,从而更准确地捕捉实体边界和类型,对古籍文本中的实体进行识别和预测。其次,本文引入多数投票(Majority Voting Combiner,MVC)和合并(Union Combiner,UC)的方法,与预测数据集进行整合并构建新的数据集,基于已识别实体数据集,使用MVC和UC方法结合NER(Named Entity Recognition)模型的预测结果重新生成新的数据集。最后,通过学习判断Sequence Labeling、Sequence Labeling_CRF、Span-level Prediction方法对实体的预测结果是否错误,并使用提示的思路对模型进行微调。为验证本文提出的方法,采用评估指标来验证模型的效果。实验结果表明,UC方法的加入使得实体识别的召回率显著提升,MVC方法提升了模型的F1值。 展开更多
关键词 序列标注 命名实体识别 二十四史 mu方法 跨度预测
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人胚肾细胞MU-K3培养条件的优化及生长特性分析
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作者 靳莉武 张震宇 +4 位作者 杨雅雯 田玲 唐晓琳 王家敏 乔自林 《中国生物制品学杂志》 2025年第5期536-542,共7页
目的优化人胚肾细胞MU-K3的培养条件,并分析其生物学特性,以期为人胚肾细胞相关生物学功能研究奠定基础。方法采用不同培养基(DMEM、MEM、M199、DME/F12)、血清种类及浓度[10%、8%、6%、4%的新生牛血清(newborn bovine serum,NBS)及10%... 目的优化人胚肾细胞MU-K3的培养条件,并分析其生物学特性,以期为人胚肾细胞相关生物学功能研究奠定基础。方法采用不同培养基(DMEM、MEM、M199、DME/F12)、血清种类及浓度[10%、8%、6%、4%的新生牛血清(newborn bovine serum,NBS)及10%的胎牛血清(fetal bovine serum,FBS)]、传代比例(1∶2、1∶4、1∶8)培养MU-K3细胞,以最大增殖浓度、倍增时间、比生长速率为评价指标确定最佳培养条件。通过流式细胞术检测MU-K3细胞周期及凋亡情况;用最佳条件对MU-K3细胞进行连续传代培养,直至细胞无法形成致密单层,衰老死亡,确定有限培养代次,并经β-半乳糖苷酶染色法分析细胞衰老情况;免疫荧光法检测细胞中波形蛋白的表达情况;Giemsa染色法分析染色体核型,评估遗传稳定性。结果确定MU-K3细胞最佳培养条件为:用含10%FBS的DMEM培养基培养,并按1∶4的比例传代。P9代MU-K3细胞S期占比为23.34%,凋亡率为10.61%,随代次增加(P17),增殖能力下降(S期占比为12.22%,凋亡率为6.38%);MU-K3细胞有限培养代次为P19,且随着代次增加,细胞中β-半乳糖苷酶活性逐渐增强,细胞逐渐衰老;MU-K3细胞呈成纤维样,染色体数目为2 n=46,属于正常人二倍体核型。结论优化了MU-K3细胞的培养条件,MU-K3为正常人二倍体细胞,且在最佳培养条件下具有稳定的增殖能力和遗传特性,可作为肾脏发育及疾病研究的理想细胞模型。 展开更多
关键词 人胚肾细胞 mu-K3细胞 细胞培养 生物学特性
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一种量子化大蕉(Mu sasapientum)果提取物对人体Ⅰ型胶原蛋白(CollagenⅠ)作用的研究
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作者 范祥翠 刘人豪 +2 位作者 秦银艺 郑华 姚艺晨 《实验室检测》 2025年第18期158-161,共4页
目的利用人体成纤维细胞作为实验模型,研究大蕉(Mu sasapientum)果实提取物对Ⅰ型胶原蛋白水平的影响,以此评估其抗衰老和提升皮肤紧致的效果。方法实验以人源成纤维细胞为测试系统,基于UVA刺激成纤维细胞抗皱、紧致功效测试规范,细胞... 目的利用人体成纤维细胞作为实验模型,研究大蕉(Mu sasapientum)果实提取物对Ⅰ型胶原蛋白水平的影响,以此评估其抗衰老和提升皮肤紧致的效果。方法实验以人源成纤维细胞为测试系统,基于UVA刺激成纤维细胞抗皱、紧致功效测试规范,细胞接种、配液、UVB辐射、给药后检测Ⅰ型胶原蛋白含量。结果样品大蕉(Mu sasapientum)果提取物在浓度为0.625%、1.250%和2.500%(体积分数)时,人源成纤维细胞Ⅰ型胶原蛋白含量显著提升,且与阴性对照组相比具有统计学差异(P<0.01)。结论大蕉(Mu sasapientum)果提取物能刺激人源成纤维细胞Ⅰ型胶原蛋白生长,具有抗皱、紧致功效。 展开更多
关键词 大蕉(mu sasapientum)果提取物 人源成纤维细胞 Ⅰ型胶原蛋白 抗皱 修复
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血清G蛋白信号调节因子2、适配器相关蛋白复合物3亚基mu2与早期结直肠癌病人临床病理特征及预后的相关性分析
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作者 孙宇 郝立政 胡晓立 《临床外科杂志》 2025年第6期623-627,共5页
目的探讨血清G蛋白信号调节因子2(GPSM2)、适配器相关蛋白复合物3亚基mu2(AP3M2)与早期结直肠癌(CRC)病人临床病理特征及其术后预后的相关性。方法2020年1月~2021年12月治疗的早期CRC病人142例(CRC组)和结直肠息肉病人96例(良性病变组)... 目的探讨血清G蛋白信号调节因子2(GPSM2)、适配器相关蛋白复合物3亚基mu2(AP3M2)与早期结直肠癌(CRC)病人临床病理特征及其术后预后的相关性。方法2020年1月~2021年12月治疗的早期CRC病人142例(CRC组)和结直肠息肉病人96例(良性病变组),同期健康志愿者80例(对照组)。采用RT-qPCR检测血清GPSM2、AP3M2水平;采用Kaplan-Meier生存曲线分析血清GPSM2、AP3M2表达与CRC病人预后的关系;Cox回归分析影响CRC病人预后的危险因素;ROC曲线分析血清GPSM2、AP3M2对CRC病人预后的预测价值。结果良性病变组和CRC组血清GPSM2、AP3M2水平高于对照组,且CRC组高于良性病变组,差异有统计学意义(P<0.05)。CRC病人血清GPSM2、AP3M2水平与其分化程度有关(P<0.05)。GPSM2、AP3M2低表达病人3年生存率均高于GPSM2、AP3M2高表达病人(85.29%、87.14%vs 67.57%、65.28%)(Log rankχ^(2)=7.205、10.800,P<0.05)。低分化程度以及血清GPSM2、AP3M2水平升高是影响CRC病人预后的危险因素(P<0.05)。血清GPSM2、AP3M2联合预测CRC病人预后的AUC为0.903(Z_(二者联合-GPSM2)=2.882、Z_(二者联合-AP3M2)=3.322,P<0.05),敏感性为88.24%,特异性为82.41。结论CRC病人血清GPSM2、AP3M2水平升高,与分化程度及预后密切相关,二者联合预测CRC病人预后具有较高的临床价值。 展开更多
关键词 结直肠癌 G蛋白信号调节因子2 适配器相关蛋白复合物3亚基mu2 临床病理特征 预后
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使用lambda-mu-sigma法的川崎病患儿冠状动脉Z值改良评估模型构建及临床验证
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作者 赵小佩 肖婷婷 +1 位作者 宋思瑞 黄敏 《上海医学》 2025年第7期437-444,共8页
目的使用lambda-mu-sigma(LMS)法建立经体表面积(BSA)校正的冠状动脉Z值改良评估模型,验证其在川崎病合并冠状动脉病变(CAL)中的预测效能,并分析其与传统二维测量法的一致性差异。方法纳入2014年5月—2022年12月期间在上海市儿童医院心... 目的使用lambda-mu-sigma(LMS)法建立经体表面积(BSA)校正的冠状动脉Z值改良评估模型,验证其在川崎病合并冠状动脉病变(CAL)中的预测效能,并分析其与传统二维测量法的一致性差异。方法纳入2014年5月—2022年12月期间在上海市儿童医院心内科接受检查及治疗的所有儿童资料,共2309人,其中1710例健康儿童作为训练组构建冠状动脉Z值评估模型,599例川崎病患儿作为测试组进行验证。对训练组用线性、对数线性、幂指数、平方根函数和LMS法模型进行模拟拟合并验证判断效能。使用LMS法建立Z值计算模型。采用Kappa检验分析改良评估模型与传统二维测量法诊断测试组患儿CAL冠状动脉病变检出率的一致性。结果训练组男性儿童月龄显著小于女性儿童,男性儿童的右冠状动脉(RCA)和左冠状动脉(LCA)内径绝对值均显著大于女性(P值均<0.05)。测试组男性患儿的LCA内径绝对值显著大于女性(P<0.05)。在训练组模拟拟合中,以BSA为自变量的LMS法模型的贝叶斯信息准则(BIC)最低(男性-4790.0,女性-4254.5),低于线性模型等传统模型,为最优拟合模型。Z值改良评估模型的CAL检出率为16.2%(97/599),显著高于传统二维测量法的10.4%(62/599)(P<0.001)。两种方法评估CAL的一致性较低(kappa=0.345,95%CI为0.337~0.353)。结论使用LMS法的Z值改良评估模型可提高CAL的检出率,其与传统二维测量法的一致性较低,未来需进一步优化Z值阈值定义或结合多模态评估策略。 展开更多
关键词 Z值 lambda-mu-sigma法 冠状动脉病变 川崎病
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Mu-阿片受体偏向性激动剂的研究进展
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作者 杨迪 张楠 方泉 《兰州大学学报(医学版)》 2025年第9期64-73,共10页
全球范围内,约五分之一的成年人正饱受各类疼痛的折磨,这使得疼痛的治疗与管理,成为全球公共卫生领域中亟需解决的关键议题。传统阿片类药物通过激活Mu-阿片受体而发挥镇痛功效,然而,严重的副作用限制了其临床应用。近年来,大量研究显示... 全球范围内,约五分之一的成年人正饱受各类疼痛的折磨,这使得疼痛的治疗与管理,成为全球公共卫生领域中亟需解决的关键议题。传统阿片类药物通过激活Mu-阿片受体而发挥镇痛功效,然而,严重的副作用限制了其临床应用。近年来,大量研究显示,阿片类药物在体内的镇痛作用由G蛋白信号通路介导,而部分副作用则由β-arrestin信号通路介导。因而,研发Mu-阿片受体偏向性激动剂已成为低副作用镇痛药物研发的热点。本文全面梳理了Mu-阿片受体偏向性激动剂的研究进展,涵盖具有G蛋白偏向性的人工合成小分子类、肽类,以及天然化合物来源的Mu-阿片受体激动剂,旨在为G蛋白偏向性阿片类药物的研发提供参考。 展开更多
关键词 mu-阿片受体 G蛋白偏向性激动剂 镇痛 副作用 镇痛新药
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活细胞成像观察肿瘤坏死因子α诱导的人支气管上皮细胞谷胱甘肽S-转移酶MU 5核转位情况
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作者 曾燕婷 张佳坷 +3 位作者 袁伟锋 何文源 徐虹 李理 《联勤军事医学》 2025年第5期371-377,共7页
目的建立肿瘤坏死因子α(tumor necrosis factor alpha,TNF-α)诱导的人支气管上皮细胞(human bronchus epithelial,16HBE)炎症模型,观察谷胱甘肽S-转移酶MU 5(glutathione S-transferase MU 5,GSTM5)核转位动态过程,探讨GSTM5对炎症和... 目的建立肿瘤坏死因子α(tumor necrosis factor alpha,TNF-α)诱导的人支气管上皮细胞(human bronchus epithelial,16HBE)炎症模型,观察谷胱甘肽S-转移酶MU 5(glutathione S-transferase MU 5,GSTM5)核转位动态过程,探讨GSTM5对炎症和氧化应激的影响。方法GSTM5真核表达载体和小干扰核糖核酸(small interfering RNA,siRNA)转染16HBE细胞后,以TNF-α处理。将实验分为7个组:16HBE组、16HBE+TNF-α组(TNF-α刺激)、16HBE+con083+TNF-α组(转染con083-GFP重组质粒,TNF-α刺激)、16HBE+GSTM5组(转染GV230-GSTM5-GFP)、16HBE+GSTM5+TNF-α组(转染GV230-GSTM5-GFP,TNF-α刺激)、16HBE+siGSTM5+TNF-α组(加入沉默GSTM5的siRNA,TNF-α刺激)、16HBE+NCsiRNA+TNF-α组(加入阴性对照siRNA,TNF-α刺激)。通过蛋白免疫印迹分析、活细胞成像和共聚焦显微镜观察GSTM5核转位的动态过程。四甲基偶氮唑盐(methylthiazolyldiphenyl-tetrazolium bromide,MTT)评估16HBE的细胞存活率,丙二醛(malondialdehyde,MDA)、总抗氧化能力(total antioxidative capacity,T-AOC)评估炎症氧化应激水平。酶联免疫吸附分析(enzyme-linked immunosorbent assay,ELISA)测定各组细胞上清液中白细胞介素6(interleukin 6,IL-6)、白细胞介素10(interleukin 10,IL-10)的浓度。结果16HBE细胞经TNF-α处理0.5 h后,细胞核内绿色荧光增强,提示GSTM5转移到16HBE细胞核内。TNF-α能显著降低16HBE细胞存活率和T-AOC,GSTM5能降低IL-6、IL-10和MDA水平。16HBE+TNF-α组IL-6、IL-10显著高于16HBE+GSTM5+TNF-α组(P<0.001)。结论TNF-α刺激致炎症氧化失衡可诱导16HBE株中GSTM5发生核转位,活细胞成像记录了其动态变化过程。 展开更多
关键词 谷胱甘肽S-转移酶mu5 人支气管上皮细胞 核转位 肿瘤坏死因子Α 活细胞成像
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Dynamic evolution of the NDVI and driving factors in the Mu Us Sandy Land of China from 2002 to 2021
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作者 CHAO Yan ZHU Yonghua +2 位作者 WANG Xiaohan LI Jiamin LIANG Li'e 《Journal of Arid Land》 2025年第5期605-623,共19页
Investigating the spatiotemporal evolution of vegetation and its response mechanisms to natural and anthropogenic elements is crucial for regional vegetation restoration and ecological preservation.The Mu Us Sandy Lan... Investigating the spatiotemporal evolution of vegetation and its response mechanisms to natural and anthropogenic elements is crucial for regional vegetation restoration and ecological preservation.The Mu Us Sandy Land(MUSL),which is situated in the semi-arid zone of northwestern China adjacent to the Loess Plateau,has been at the forefront of desertification and oasis formation over the past two millennia.This study is based on the synthesis of the Normalized Difference Vegetation Index(NDVI)data from MOD13A3 data in the MODIS(Moderate-Resolution Imaging Spectroradiometer)dataset(2002-2021)and climate data(temperature and precipitation)at annual and monthly scales from the National Earth System Science Data Center.A range of analytical methods,including univariate linear regression,Theil-Sen trend analysis and Mann-Kendall significance test,correlation analysis,residual analysis,and Hurst index,were used to explore the response mechanisms of the NDVI to climate change and human activities and to predict the future trends of the NDVI in the MUSL.The results showed that through the method of correlation analysis,in terms of both spatially averaged correlation coefficients and area proportion,the NDVI was positively correlated with temperature and precipitation in 97.59%and 96.51%of the study area,respectively,indicating that temperature has a greater impact on the NDVI than precipitation.Residual analysis quantified the contributions of climate change and human activities to the NDVI changes,revealing that climate change and human activities contribute up to 30.00%and 70.00%,respectively,suggesting that human activities predominantly affect the NDVI changes in the MUSL.The Hurst index was used to categorize the future trend of the NDVI into four main directions of development:continuous degradation(0.05%of the study area),degradation in the past but improvement in the future(54.45%),improvement in the past but degradation in the future(0.13%),and continuous improvement(45.36%).In more than 50.00%of the regions that have been degraded in the past but were expected to improve in the future,the NDVI was expected to exhibit a stable trend of anti-persistent improvement.These findings provide theoretical support for future ecological protection,planning,and the implementation of ecological engineering in the MUSL,and also offer a theoretical basis for the planning and execution of construction projects,environmental protection measures,and the sustainable development of vegetation. 展开更多
关键词 Normalized Difference Vegetation Index(NDVI) climate change human activities residual analysis Hurst index mu Us Sandy Land
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Exploring macrophage polarization as a prognostic indicator for colorectal cancer:Unveiling the impact of metalloproteinase mutations
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作者 Eduardo Brambilla Daniel Jun Funatsu Brambilla +3 位作者 Aline Caldart Tregnago Floriano Riva Fabio Firmbach Pasqualotto Jonathan Soldera 《World Journal of Clinical Cases》 2025年第23期10-23,共14页
BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes co... BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes could have significant prognostic implications,and manipulating this polarization may offer a novel approach to controlling colorectal neoplasms.AIM To evaluate the infiltration rates of M1 and M2 macrophages in colorectal neoplasia,specifically comparing cases with and without metalloproteinase mutations.Additionally,it sought to explore potential prognostic factors as-sociated with the disease. 展开更多
关键词 metalloproteinase mu colorectal neoplasiaspecifically manipulating polarization controlling colorectal neoplasmsaim macrophage polarization m m macrophages infiltration rates m m phenotypes
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Assessment of ecological geological vulnerability in Mu Us Sandy Land based on GIS and suggestions of ecological protection and restoration
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作者 Jian-yu Liu Hong-feng Nie +6 位作者 Liang Xu Chun-lei Xiao Wei Li Guo-li Yuan Yan-peng Huang Xin-yang Ji Tian-qi Li 《China Geology》 2025年第1期117-140,共24页
Eco-geological vulnerability assessment is a significant research topic within the field of eco-geology,but it remains poorly studied.The Mu Us Sandy Land,located in the central part of the farming-pastoral ecotone in... Eco-geological vulnerability assessment is a significant research topic within the field of eco-geology,but it remains poorly studied.The Mu Us Sandy Land,located in the central part of the farming-pastoral ecotone in northern China,plays a critical role in maintaining the ecological security pattern in this region.However,this sandy land also faces severe sandy desertification and ecological degradation.This study conducted a regional eco-geological vulnerability assessment of the Mu Us Sandy Land using a comprehensive index evaluation method based on eco-geological theories and survey results.To construct an appropriate index system for the eco-geological vulnerability assessment of the Mu Us Sandy Land,the study considered the sandy land’s unique characteristics and identified 15 factors of five categories,namely geology,meteorology,soil,topography,and vegetation.The paper calculated the comprehensive weights of all the indices using the analytic hierarchy process(AHP)and the entropy weight method(EWM).Furthermore,it established the eco-geological vulnerability index(EGVI)and obtained the assessment results.The results showed that the eco-geological vulnerability of the Mu Us Sandy Land gradually intensifies from east to west,manifested as vulnerable eco-geological conditions overall.Specifically,extremely vulnerable zones are found in the northwestern and southeastern parts of the study area,highly vulnerable zones in the western and southern parts,moderately vulnerable zones in the central part,and slightly and potentially vulnerable zones in the eastern and southern parts.Areas with high spatial autocorrelations include the northern Uxin Banner-Otog Banner-Angsu Town area,the surrounding areas of Hongdunjie Town in the southeastern part of the study area,the Hongshiqiao Township-Xiaohaotu Township area,Otog Front Banner,and Bainijing Town,which should be prioritized in the ecological conservation and restoration.Additionally,the paper proposed suggestions for the ecological conservation and restoration of county-level administrative areas in the study area.Overall,the findings provide a valuable reference for the ecological conservation and restoration of the Mu Us Sandy Land and other desert areas in arid and semi-arid regions. 展开更多
关键词 Eco-geological vulnerability Analytic hierarchy process Entropy weight method Evaluation and zonation mu Us Sandy Land Geology-meteorology-soil-topography-vegetation Precipitation and groundwater Environmental protection and restoration Environmental restoration engineering Inner Mongolia Plateau
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MU-MIMO在Wi-Fi中的实际应用与性能优化建议
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作者 谢易辰 贺丽娟 +2 位作者 李立新 裴伯硙 冯志芳 《无线互联科技》 2025年第3期15-18,共4页
随着无线保真(Wireless Fidelity,Wi-Fi)技术演进和业务需求增加,Wi-Fi网络面临着更高的性能要求。多进多出无线通信(Multiple-Input Multiple-Output,MIMO)技术,特别是多用户-多输入多输出(Multi-User Multiple-Input Multiple-Output,... 随着无线保真(Wireless Fidelity,Wi-Fi)技术演进和业务需求增加,Wi-Fi网络面临着更高的性能要求。多进多出无线通信(Multiple-Input Multiple-Output,MIMO)技术,特别是多用户-多输入多输出(Multi-User Multiple-Input Multiple-Output,MU-MIMO)技术,已成为提升Wi-Fi网络容量和频谱利用率的关键技术。文章构建了Wi-Fi 7环境下的MIMO实验,分析了MIMO技术在实际应用中的表现。实验结果表明,受限于设备资源分配、设备处理能力及能耗管理等因素,MU-MIMO技术未充分发挥其增益效果。针对实验结果,文章提出了增强设备硬件性能、优化软件和改进能耗管理等优化建议,以提升MIMO技术在Wi-Fi中的应用效果。 展开更多
关键词 mu-MIMO Wi-Fi 7 Wi-Fi网络性能
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IRS辅助MU-MISO系统中基于深度残差学习的信道估计
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作者 陈发堂 朱鹏云 +1 位作者 杨涛 孙宸 《电讯技术》 北大核心 2024年第7期1079-1087,共9页
针对智能反射表面辅助多用户通信系统中传统信道估计方法性能下降的问题,将信道估计问题转化为信道去噪问题,利用深度残差学习方法学习残差噪声,从含噪导频信号中恢复信道系数。同时为提升信道估计精度,设计信道估计网络进一步提升去噪... 针对智能反射表面辅助多用户通信系统中传统信道估计方法性能下降的问题,将信道估计问题转化为信道去噪问题,利用深度残差学习方法学习残差噪声,从含噪导频信号中恢复信道系数。同时为提升信道估计精度,设计信道估计网络进一步提升去噪性能。网络主体包含两个模块:拼接信息保留模块将每一层卷积输出相融合,防止信道特征丢失,有效提取信道噪声的主体特征;扩张卷积稀疏模块通过扩大感受野范围获得信道的重要结构和细节特征,恢复信道噪声的边缘细节特征。仿真结果表明,归一化均方误差约等于0.45时,所提方法在不明显增加复杂度情况下,相比于线性最小均方误差算法获得3.7 dB的信噪比增益,更为接近最小均方误差信道估计器的性能,表现出了更好的性能和可用性。 展开更多
关键词 mu-MISO系统 智能反射面 信道估计 深度残差学习 扩张卷积
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针对MUS求解问题的加强剪枝策略 被引量:1
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作者 蒋璐宇 欧阳丹彤 +1 位作者 董博文 张立明 《软件学报》 EI CSCD 北大核心 2024年第4期1964-1979,共16页
极小不可满足子集(minimal unsatisfiable subsets,MUS)的求解是布尔可满足性问题中的一个重要子问题.对于一个给定的不可满足问题,其MUS的求解能够反映出问题中导致其不可满足的关键原因.然而,MUS的求解是一项极其耗时的任务,不同的剪... 极小不可满足子集(minimal unsatisfiable subsets,MUS)的求解是布尔可满足性问题中的一个重要子问题.对于一个给定的不可满足问题,其MUS的求解能够反映出问题中导致其不可满足的关键原因.然而,MUS的求解是一项极其耗时的任务,不同的剪枝过程将直接影响到搜索空间的大小、算法的迭代次数,从而影响算法的求解效率.提出一种针对MUS求解的加强剪枝策略ABC(accelerating by critical MSS),依据MSS、MCS、MUS这3者之间的对偶性和碰集关系特点,提出cMSS和subMUS概念,并总结出4条性质,即每个MUS必是subMUS的超集,进而在避免对MCS的碰集进行求解的情况下有效利用MUS和MCS互为碰集的特征,有效避免求解碰集时的时间开销.当subMUS不可满足时,则subMUS是唯一的MUS,算法将提前结束执行;当subMUS可满足时,则剪枝掉此节点,进而有效避免对求解空间中的冗余空间进行搜索.同时,通过理论证明ABC策略的有效性,并将其应用于目前最高效的单一化模型算法MARCO和双模型算法MARCO-MAM,在标准测试用例下的实验结果表明,该策略可以有效地对搜索空间进行进一步剪枝,从而提高MUS的枚举效率. 展开更多
关键词 极小不可满足子集 极大可满足子集 muS枚举 幂集探索 不可行分析
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Simultaneous Waveform Inverse Modelling for Litho-Fluid Prediction in an Old Marginal, “Agbbo”Field, Onshore Niger Delta, Nigeria
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作者 Charles Chibueze Ugbor Peter Ogobi Odong Chukwuemeka Austine Okonkwo 《Journal of Geoscience and Environment Protection》 2024年第5期40-59,共20页
Simultaneous waveform inversion was used to predict lithofacies and fluid type across the field. Very often, characterizing reservoirs in terms of lithology and fluid type using conventional methods is replete with un... Simultaneous waveform inversion was used to predict lithofacies and fluid type across the field. Very often, characterizing reservoirs in terms of lithology and fluid type using conventional methods is replete with uncertainties, especially in marginal fields. An approach is employed in this study that integrated rock physics and waveform inverse modelling for lithology and fluid-type characterization to appropriately identify potential hydrocarbon saturated zones and their corresponding lithology. Seismic and well-log data were analyzed using Hampson Russel software. The method adopted includes lithofacies and fluid content analysis using rock physics parameters and seismic simultaneous inverse modelling. Rock physics analysis identified 2 broad reservoirs namely: HDZ1 and HDZ2 reservoirs. Results from the inverse modelling showed that low values of acoustic impedance from 19,743 to 20,487 (ft/s)(g/cc) reflect hydrocarbon-bearing reservoirs while medium to high values shows brine and shale respectively, with brine zone ranging from 20,487 to 22,531 (ft/s)(g/cc) and shale above 22,531 (ft/s)(g/cc). Two lithofacies were identified from inversion analysis of Vp/Vs and Mu-Rho, namely: sand and shale with VpVs 1.95 values respectively. Mu-Rho > 12.29 (GPa)(g/cc) and <12.29 (GPa) (g/cc) represent sand and shale respectively. From 3D volume, it was observed that a high accumulation of hydrocarbon was observed to be saturated at the north to the eastern part of the field forming a meandering channel. Sands were mainly distributed around the northeastern to the southwestern part of the field, that tends to be away from Well 029. This was also validated by the volume of rigidity modulus (Mu-Rho) showing high values indicating sands fall within the northeastern part of the field. 展开更多
关键词 Simultaneous Waveform Inversion Lithofacies Fluid Type Rock Physics HYDROCARBON Acoustic Impedance mu-Rho Reservoir
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Mutator转座子及MULE在植物基因与基因组进化中的作用(英文) 被引量:4
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作者 刁现民 Damon Lisch 《Acta Genetica Sinica》 SCIE CAS CSCD 北大核心 2006年第6期477-487,共11页
Mutator(Mu)转座子是植物中已发现的转座最活跃的转座子,其高的转座频率及趋向于单拷贝功能基因转座的特性,使该转座子成为玉米功能基因克隆的主要方法。Mu转座子的同源类似因子广泛存在于被子植物基因组中,而且同一基因组中往往具有多... Mutator(Mu)转座子是植物中已发现的转座最活跃的转座子,其高的转座频率及趋向于单拷贝功能基因转座的特性,使该转座子成为玉米功能基因克隆的主要方法。Mu转座子的同源类似因子广泛存在于被子植物基因组中,而且同一基因组中往往具有多种变异类型。它不仅具有其他DNA转座子在基因和基因组进化中的普遍作用,而且具有能够承载基因组内功能基因和基因片段的载体功能,这种载体Mu转座子(Pack-MuLEs)能够在基因组内移动众多的基因片段,从而对基因和基因组进化产生作用。Mu转座子的同源序列发生在水稻与狗尾草之间的水平转移提供了高等植物核基因水平转移的首个例证。对Mu转座子的了解促进了我们对动态基因组概念的认识。文章对Mutator转座子的发现、转座特征、基因标签应用等的研究进展进行了综述,对Mu转座子家族的同源序列进行了分类,讨论了该转座子在基因组进化中的作用,分析了应加强研究的问题。 展开更多
关键词 mutator 转座子 基因组进化 muLE 载体mu转座子
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藏语dmu rmu mu smu de.mu等词的关系研究
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作者 华毛加 《青海民族大学学报(藏文版)》 2022年第2期57-64,共8页
在藏族史上,传说聂赤赞普是沿着天神绳梯「dmuthag」降临人间,此天绳「dmuthag」被认为是源自天堂之物。然而,据史书记载,穆氏(dmu)出现于在此之前,且认为穆氏属于神的氏族。如今,从西藏阿里到卫藏,以及安多各地仍留存着「dmuskas」和「... 在藏族史上,传说聂赤赞普是沿着天神绳梯「dmuthag」降临人间,此天绳「dmuthag」被认为是源自天堂之物。然而,据史书记载,穆氏(dmu)出现于在此之前,且认为穆氏属于神的氏族。如今,从西藏阿里到卫藏,以及安多各地仍留存着「dmuskas」和「dmuthag」文化,此乃同一事物的不同表现,而「dmuthag」是基于羊被视为天堂降世的传说而夸赞羊毛的称呼。在藏语中,吐蕃四大姓氏之一[dmu]有[mu]和[dmu]两种写法,据此形成了[dmuthag][dmuskas]和[dmurdo]等词。本文根据嘉绒和古象雄文化中用[mu]指天空,同时存在使用[dmu]的现象(即[mu]加前加字[de],论证了[dmu][rmu][smu][mu]等是同一词的不同写法,实指天空或天堂。 展开更多
关键词 Dmu rmu mu smu de.mu
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Ecological effect of the plantation of Sabina vulgaris in the Mu Us Sandy Land,China 被引量:3
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作者 NAN Weige DONG Zhibao +2 位作者 ZHOU Zhengchao LI Qiang CHEN Guoxiang 《Journal of Arid Land》 SCIE CSCD 2024年第1期14-28,共15页
Vegetation restoration through artificial plantation is an effective method to combat desertification,especially in arid and semi-arid areas.This study aimed to explore the ecological effect of the plantation of Sabin... Vegetation restoration through artificial plantation is an effective method to combat desertification,especially in arid and semi-arid areas.This study aimed to explore the ecological effect of the plantation of Sabina vulgaris on soil physical and chemical properties on the southeastern fringe of the Mu Us Sandy Land,China.We collected soil samples from five depth layers(0-20,20-40,40-60,60-80,and 80-100 cm)in the S.vulgaris plantation plots across four plantation ages(4,7,10,and 16 years)in November 2019,and assessed soil physical(soil bulk density,soil porosity,and soil particle size)and chemical(soil organic carbon(SOC),total nitrogen(TN),available nitrogen(AN),available phosphorus(AP),available potassium(AK),cation-exchange capacity(CEC),salinity,p H,and C/N ratio)properties.The results indicated that the soil predominantly consisted of sand particles(94.27%-99.67%),with the remainder being silt and clay.As plantation age increased,silt and very fine sand contents progressively rose.After 16 years of planting,there was a marked reduction in the mean soil particle size.The initial soil fertility was low and declined from 4 to 10 years of planting before witnessing an improvement.Significant positive correlations were observed for the clay,silt,and very fine sand(mean diameter of 0.000-0.100 mm)with SOC,AK,and p H.In contrast,fine sand and medium sand(mean diameter of 0.100-0.500 mm)showed significant negative correlations with these indicators.Our findings ascertain that the plantation of S.vulgaris requires 10 years to effectively act as a windbreak and contribute to sand fixation,and needs 16 years to improve soil physical and chemical properties.Importantly,these improvements were found to be highly beneficial for vegetation restoration in arid and semi-arid areas.This research can offer valuable insights for the protection and restoration of the vegetation ecosystem in the sandy lands in China. 展开更多
关键词 Sabina vulgaris plantation age soil physical and chemical properties soil particle size soil fertility vegetation restoration mu Us Sandy Land
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Vertical distribution characteristics of soil saturated hydraulic conductivity under different land use patterns in the Mu Us sandy land 被引量:4
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作者 LIU Xingting QIAO Jiangbo +4 位作者 YANG Tao MA Yali TIAN Hanyang HAN Xiaoyang ZHU Yuanjun 《地球环境学报》 CSCD 2024年第4期665-674,共10页
Background,aim,and scope Soil saturated hydraulic conductivity(K_(s))is a key parameter in the hydrological cycle of soil;however,we have very limited understanding of K_(s) characteristics and the factors that inf lu... Background,aim,and scope Soil saturated hydraulic conductivity(K_(s))is a key parameter in the hydrological cycle of soil;however,we have very limited understanding of K_(s) characteristics and the factors that inf luence this key parameter in the Mu Us sandy land(MUSL).Quantifying the impact of changes in land use in the Mu Us sandy land on K_(s) will provide a key foundation for understanding the regional water cycle,but will also provide a scientific basis for the governance of the MUSL.Materials and methods In this study,we determined K_(s) and the basic physical and chemical properties of soil(i.e.,organic matter,bulk density,and soil particle composition)within the first 100 cm layer of four different land use patterns(farmland,tree,shrub,and grassland)in the MUSL.The vertical variation of K_(s) and the factors that influence this key parameter were analyzed and a transfer function for estimating K_(s) was established based on a multiple stepwise regression model.Results The K_(s) of farmland,tree,and shrub increased gradually with soil depth while that of grassland remained unchanged.The K_(s) of the four patterns of land use were moderately variable;mean K_(s)values were ranked as follows:grassland(1.38 mm·min^(-1))<tree(1.76 mm·min^(-1))<farmland(1.82 mm·min^(-1))<shrub(3.30 mm·min^(-1)).The correlation between K_(s) and organic matter,bulk density,and soil particle composition,varied across different land use patterns.A multiple stepwise regression model showed that silt,coarse sand,bulk density,and organic matter,were key predictive factors for the K_(s) of farmland,tree,shrub,and grassland,in the MUSL.Discussion The vertical distribution trend for K_(s) in farmland is known to be predominantly influenced by cultivation,fertilization,and other factors.The general aim is to improve the water-holding capacity of shallow soil on farmland(0-30 cm in depth)to conserve water and nutrients;research has shown that the K_(s) of farmland increases with soil depth.The root growth of tree and shrub in sandy land exerts mechanical force on the soil due to biophysical processes involving rhizospheres,thus leading to a significant change in K_(s).We found that shallow high-density fine roots increased the volume of soil pores and eliminated large pores,thus resulting in a reduction in shallow K_(s).Therefore,the K_(s) of tree and shrub increased with soil depth.Analysis also showed that the K_(s) of grassland did not change significantly and exhibited the lowest mean value when compared to other land use patterns.This finding was predominantly due to the shallow root system of grasslands and because this land use pattern is not subject to human activities such as cultivation and fertilization;consequently,there was no significant change in K_(s) with depth;grassland also had the lowest mean K_(s).We also established a transfer function for K_(s) for different land use patterns in the MUSL.However,the predictive factors for K_(s) in different land use patterns are known to be affected by soil cultivation methods,vegetation restoration modes,the distribution of soil moisture,and other factors,thus resulting in key differences.Therefore,when using the transfer function to predict K_(s) in other areas,it will be necessary to perform parameter calibration and further verification.Conclusions In the MUSL,the K_(s) of farmland,tree,and shrub gradually increased with soil depth;however,the K_(s) of grassland showed no significant variation in terms of vertical distribution.The mean K_(s) values of different land use patterns were ranked as follows:shrub>farmland>tree>grassland;all land use patterns showed moderate levels of variability.The K_(s) for different land use patterns exhibited differing degrees of correlation with soil physical and chemical properties;of these,clay,silt,sand,bulk density,and organic matter,were identified as important variables for predicting K_(s) in farmland,tree,shrub,and grassland,respectively.Recommendations and perspectives In this study,we used a stepwise multiple regression model to establish a transfer function prediction model for K_(s) for different land use patterns;this model possessed high estimation accuracy.The ability to predict K_(s) in the MUSL is very important in terms of the conservation of water and nutrients. 展开更多
关键词 mu Us sandy land saturated hydraulic conductivity vertical distribution transfer function
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