Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often stru...Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.展开更多
The diagnosis of brain tumors is an extended process that significantly depends on the expertise and skills of radiologists.The rise in patient numbers has substantially elevated the data processing volume,making conv...The diagnosis of brain tumors is an extended process that significantly depends on the expertise and skills of radiologists.The rise in patient numbers has substantially elevated the data processing volume,making conventional methods both costly and inefficient.Recently,Artificial Intelligence(AI)has gained prominence for developing automated systems that can accurately diagnose or segment brain tumors in a shorter time frame.Many researchers have examined various algorithms that provide both speed and accuracy in detecting and classifying brain tumors.This paper proposes a newmodel based on AI,called the Brain Tumor Detection(BTD)model,based on brain tumor Magnetic Resonance Images(MRIs).The proposed BTC comprises three main modules:(i)Image Processing Module(IPM),(ii)Patient Detection Module(PDM),and(iii)Explainable AI(XAI).In the first module(i.e.,IPM),the used dataset is preprocessed through two stages:feature extraction and feature selection.At first,the MRI is preprocessed,then the images are converted into a set of features using several feature extraction methods:gray level co-occurrencematrix,histogramof oriented gradient,local binary pattern,and Tamura feature.Next,the most effective features are selected fromthese features separately using ImprovedGrayWolfOptimization(IGWO).IGWOis a hybrid methodology that consists of the Filter Selection Step(FSS)using information gain ratio as an initial selection stage and Binary Gray Wolf Optimization(BGWO)to make the proposed method better at detecting tumors by further optimizing and improving the chosen features.Then,these features are fed to PDM using several classifiers,and the final decision is based on weighted majority voting.Finally,through Local Interpretable Model-agnostic Explanations(LIME)XAI,the interpretability and transparency in decision-making processes are provided.The experiments are performed on a publicly available Brain MRI dataset that consists of 98 normal cases and 154 abnormal cases.During the experiments,the dataset was divided into 70%(177 cases)for training and 30%(75 cases)for testing.The numerical findings demonstrate that the BTD model outperforms its competitors in terms of accuracy,precision,recall,and F-measure.It introduces 98.8%accuracy,97%precision,97.5%recall,and 97.2%F-measure.The results demonstrate the potential of the proposed model to revolutionize brain tumor diagnosis,contribute to better treatment strategies,and improve patient outcomes.展开更多
Brain tumor segmentation is critical in clinical diagnosis and treatment planning.Existing methods for brain tumor segmentation with missing modalities often struggle when dealing with multiple missing modalities,a co...Brain tumor segmentation is critical in clinical diagnosis and treatment planning.Existing methods for brain tumor segmentation with missing modalities often struggle when dealing with multiple missing modalities,a common scenario in real-world clinical settings.These methods primarily focus on handling a single missing modality at a time,making them insufficiently robust for the additional complexity encountered with incomplete data containing various missing modality combinations.Additionally,most existing methods rely on single models,which may limit their performance and increase the risk of overfitting the training data.This work proposes a novel method called the ensemble adversarial co-training neural network(EACNet)for accurate brain tumor segmentation from multi-modal magnetic resonance imaging(MRI)scans with multiple missing modalities.The proposed method consists of three key modules:the ensemble of pre-trained models,which captures diverse feature representations from the MRI data by employing an ensemble of pre-trained models;adversarial learning,which leverages a competitive training approach involving two models;a generator model,which creates realistic missing data,while sub-networks acting as discriminators learn to distinguish real data from the generated“fake”data.Co-training framework utilizes the information extracted by the multimodal path(trained on complete scans)to guide the learning process in the path handling missing modalities.The model potentially compensates for missing information through co-training interactions by exploiting the relationships between available modalities and the tumor segmentation task.EACNet was evaluated on the BraTS2018 and BraTS2020 challenge datasets and achieved state-of-the-art and competitive performance respectively.Notably,the segmentation results for the whole tumor(WT)dice similarity coefficient(DSC)reached 89.27%,surpassing the performance of existing methods.The analysis suggests that the ensemble approach offers potential benefits,and the adversarial co-training contributes to the increased robustness and accuracy of EACNet for brain tumor segmentation of MRI scans with missing modalities.The experimental results show that EACNet has promising results for the task of brain tumor segmentation of MRI scans with missing modalities and is a better candidate for real-world clinical applications.展开更多
The automatic localization of the left ventricle(LV)in short-axis magnetic resonance(MR)images is a required step to process cardiac images using convolutional neural networks for the extraction of a region of interes...The automatic localization of the left ventricle(LV)in short-axis magnetic resonance(MR)images is a required step to process cardiac images using convolutional neural networks for the extraction of a region of interest(ROI).The precise extraction of the LV’s ROI from cardiac MRI images is crucial for detecting heart disorders via cardiac segmentation or registration.Nevertheless,this task appears to be intricate due to the diversities in the size and shape of the LV and the scattering of surrounding tissues across different slices.Thus,this study proposed a region-based convolutional network(Faster R-CNN)for the LV localization from short-axis cardiac MRI images using a region proposal network(RPN)integrated with deep feature classification and regression.Themodel was trained using images with corresponding bounding boxes(labels)around the LV,and various experiments were applied to select the appropriate layers and set the suitable hyper-parameters.The experimental findings showthat the proposed modelwas adequate,with accuracy,precision,recall,and F1 score values of 0.91,0.94,0.95,and 0.95,respectively.This model also allows the cropping of the detected area of LV,which is vital in reducing the computational cost and time during segmentation and classification procedures.Therefore,itwould be an ideal model and clinically applicable for diagnosing cardiac diseases.展开更多
Computed tomography(CT) reconstruction with a well-registered priori magnetic resonance imaging(MRI) image can improve reconstruction results with low-dose CT, because well-registered CT and MRI images have similar st...Computed tomography(CT) reconstruction with a well-registered priori magnetic resonance imaging(MRI) image can improve reconstruction results with low-dose CT, because well-registered CT and MRI images have similar structures. However, in clinical settings, the CT image of patients does not always match the priori MRI image because of breathing and movement of patients during CT scanning. To improve the image quality in this case, multi-group datasets expansion is proposed in this paper. In our method, multi-group CT-MRI datasets are formed by expanding CT-MRI datasets. These expanded datasets can also be used by most existing CT-MRI algorithms and improve the reconstructed image quality when the CT image of a patient is not registered with the priori MRI image. In the experiments, we evaluate the performance of the algorithm by using multi-group CT-MRI datasets in several unregistered situations. Experiments show that when the CT and priori MRI images are not registered, the reconstruction results of using multi-group dataset expansion are better than those obtained without using the expansion.展开更多
Electrical impedance tomography(EIT)image reconstruction is a non-linear problem.In general,finite element model is the critical basis of EIT image reconstruction.A 3D human thorax modeling method for EIT image recons...Electrical impedance tomography(EIT)image reconstruction is a non-linear problem.In general,finite element model is the critical basis of EIT image reconstruction.A 3D human thorax modeling method for EIT image reconstruction is proposed herein to improve the accuracy and reduce the complexity of existing finite element modeling methods.The contours of human thorax and lungs are extracted from the layers of magnetic resonance imaging(MRI)images by an optimized Otsu’s method for the construction of the 3D human thorax model including the lung models.Furthermore,the GMSH tool is used for finite element subdivision to generate the 3D finite element model of human thorax.The proposed modeling method is fast and accurate,and it is universal for different types of MRI images.The effectiveness of the proposed method is validated by extensive numerical simulation in MATLAB.The results show that the individually oriented 3D finite element model can improve the reconstruction quality of the EIT images more effectively than the cylindrical model,the 2.5D model and other human chest models.展开更多
Attention mechanism combined with convolutional neural network(CNN) achieves promising performance for magnetic resonance imaging(MRI) image segmentation,however these methods only learn attention weights from single ...Attention mechanism combined with convolutional neural network(CNN) achieves promising performance for magnetic resonance imaging(MRI) image segmentation,however these methods only learn attention weights from single scale,resulting in incomplete attention learning.A novel method named completed attention convolutional neural network(CACNN) is proposed for MRI image segmentation.Specifically,the channel-wise attention block(CWAB) and the pixel-wise attention block(PWAB) are designed to learn attention weights from the aspects of channel and pixel levels.As a result,completed attention weights are obtained,which is beneficial to discriminative feature learning.The method is verified on two widely used datasets(HVSMR and MRBrainS),and the experimental results demonstrate that the proposed method achieves better results than the state-of-theart methods.展开更多
Magnetic resonance imaging(MRI)is one of the most prevalent imaging modalities used for diagnosis,treatment planning,and outcome control in various medical conditions.MRI sequences provide physicians with the ability ...Magnetic resonance imaging(MRI)is one of the most prevalent imaging modalities used for diagnosis,treatment planning,and outcome control in various medical conditions.MRI sequences provide physicians with the ability to view and monitor tissues at multiple contrasts within a single scan and serve as input for automated systems to perform downstream tasks.However,in clinical practice,there is usually no concise set of identically acquired sequences for a whole group of patients.As a consequence,medical professionals and automated systems both face difficulties due to the lack of complementary information from such missing sequences.This problem is well known in computer vision,particularly in medical image processing tasks such as tumor segmentation,tissue classification,and image generation.With the aim of helping researchers,this literature review examines a significant number of recent approaches that attempt to mitigate these problems.Basic techniques such as early synthesis methods,as well as later approaches that deploy deep learning,such as common latent space models,knowledge distillation networks,mutual information maximization,and generative adversarial networks(GANs)are examined in detail.We investigate the novelty,strengths,and weaknesses of the aforementioned strategies.Moreover,using a case study on the segmentation task,our survey offers quantitative benchmarks to further analyze the effectiveness of these methods for addressing the missing modalities challenge.Furthermore,a discussion offers possible future research directions.展开更多
Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people everywhere.Due to its ability to produce a detailed view of the soft tissues,including the s...Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people everywhere.Due to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the spine.The semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar diseases.It is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation accuracy.This work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra S1.Pseudo-colour mask images were generated and used as ground truth for training the model.The work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar Spine MRI Dataset publicly available from Mendeley Data.The proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DSC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.展开更多
Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity ...Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity of pathology,potentially hindering clinical trials in the development of medical treatment.Brain-based subtyping studies utilize magnetic resonance imaging(MRI)and data-driven methods to discover the subtypes of diseases,providing a new perspective on disease heterogeneity.展开更多
In neuropathological diseases such as Alzheimer's Disease(AD),neuroimaging and Magnetic Resonance Imaging(MRI)play crucial roles in the realm of Artificial Intelligence of Medical Things(AIoMT)by leveraging edge i...In neuropathological diseases such as Alzheimer's Disease(AD),neuroimaging and Magnetic Resonance Imaging(MRI)play crucial roles in the realm of Artificial Intelligence of Medical Things(AIoMT)by leveraging edge intelligence resources.However,accurately classifying MRI scans based on neurodegenerative diseases faces challenges due to significant variability across classes and limited intra-class differences.To address this challenge,we propose a novel approach aimed at improving the early detection of AD through MRI imaging.This method integrates a Convolutional Neural Network(CNN)with a Cascade Attention Model(CAM-CNN).The CAM-CNN model outperforms traditional CNNs in AD classification accuracy and processing complexity.In this architecture,the attention mechanism is effectively implemented by utilizing two constraint cost functions and a cross-network with diverse pre-trained parameters for a two-stream architecture.Additionally,two new cost functions,Satisfied Rank Loss(SRL)and Cross-Network Similarity Loss(CNSL),are introduced to enhance collaboration and overall network performance.Finally,a unique entropy addition method is employed in the attention module for network integration,converting intermediate outcomes into the final prediction.These components are designed to work collaboratively and can be sequentially trained for optimal performance,thereby enhancing the effectiveness of AD stage classification and robustness to interference from MR images.Validation using the Kaggle dataset demonstrates the model's accuracy of 99.07%in multiclass classification,ensuring precise classification and early detection of all AD subtypes.Further validation across three feature categories with varying numbers confirms the robustness of the proposed approach,with deviations from the standard criteria of less than 1%.Applied in Alzheimer's patient care,this capability holds promise for enhancing value-based therapy and clinical decision-making.It aids in differentiating Alzheimer's patients from healthy individuals,thereby improving patient care and enabling more targeted therapies.展开更多
<span style="font-family:Verdana;">Rationale and Objectives: Accurately establishing the diagnosis and staging of cervical and thyroid cancers is essential in medical practice in determining tumor exte...<span style="font-family:Verdana;">Rationale and Objectives: Accurately establishing the diagnosis and staging of cervical and thyroid cancers is essential in medical practice in determining tumor extension and dissemination and involves the most accurate and effective therapeutic approach. For accurate diagnosis and staging of cervical and thyroid cancers, we aim to create a diagnostic method, optimized by the algorithms of artificial intelligence and validated by achieving accurate and favorable results by conducting a clinical trial, during which we will use the diagnostic method optimized by artificial intelligence (AI) algorithms, to avoid errors, to increase the understanding on interpretation computer tomography (CT) scan, magnetic resonance imaging (MRI) of the doctor and improve therapeutic planning. Materials and Methods: The optimization of the computer assisted diagnosis (CAD) method will consist in the development and formation of artificial intelligence models, using algorithms and tools used in segmental volumetric constructions to generate 3D images from MRI/CT. We propose a comparative study of current developments in “DICOM” image processing by volume rendering technique, the use of the transfer function for opacity and color, shades of gray from “DICOM” images projected in a three-dimensional space. We also use artificial intelligence (AI), through the technique of Generative Adversarial Networks (GAN), which has proven to be effective in representing complex data distributions, as we do in this study. Validation of the diagnostic method, optimized by algorithm of artificial intelligence will consist of achieving accurate results on diagnosis and staging of cervical and thyroid cancers by conducting a randomized, controlled clinical trial, for a period of 17 months. Results: We will validate the CAD method through a clinical study and, secondly, we use various network topologies specified above, which have produced promising results in the tasks of image model recognition and by using this mixture. By using this method in medical practice, we aim to avoid errors, provide precision in diagnosing, staging and establishing the therapeutic plan in cancers of the cervix and thyroid using AI. Conclusion: The use of the CAD method can increase the quality of life by avoiding intra and postoperative complications in surgery, intraoperative orientation and the precise determination of radiation doses and irradiation zone in radiotherapy.</span>展开更多
Detecting brain tumours is complex due to the natural variation in their location, shape, and intensity in images. While having accurate detection and segmentation of brain tumours would be beneficial, current methods...Detecting brain tumours is complex due to the natural variation in their location, shape, and intensity in images. While having accurate detection and segmentation of brain tumours would be beneficial, current methods still need to solve this problem despite the numerous available approaches. Precise analysis of Magnetic Resonance Imaging (MRI) is crucial for detecting, segmenting, and classifying brain tumours in medical diagnostics. Magnetic Resonance Imaging is a vital component in medical diagnosis, and it requires precise, efficient, careful, efficient, and reliable image analysis techniques. The authors developed a Deep Learning (DL) fusion model to classify brain tumours reliably. Deep Learning models require large amounts of training data to achieve good results, so the researchers utilised data augmentation techniques to increase the dataset size for training models. VGG16, ResNet50, and convolutional deep belief networks networks extracted deep features from MRI images. Softmax was used as the classifier, and the training set was supplemented with intentionally created MRI images of brain tumours in addition to the genuine ones. The features of two DL models were combined in the proposed model to generate a fusion model, which significantly increased classification accuracy. An openly accessible dataset from the internet was used to test the model's performance, and the experimental results showed that the proposed fusion model achieved a classification accuracy of 98.98%. Finally, the results were compared with existing methods, and the proposed model outperformed them significantly.展开更多
The diagnostic potential of brain positron emission tomography （PET） imaging is limited by low spatial resolution. For solving this problem we propose a technique for the fusion of PET and MRI images. This fusion is...The diagnostic potential of brain positron emission tomography （PET） imaging is limited by low spatial resolution. For solving this problem we propose a technique for the fusion of PET and MRI images. This fusion is a trade-off between the spectral information extracted from PET images and the spatial information extracted from high spatial resolution MRI. The proposed method can control this trade-off. To achieve this goal, it is necessary to build a multiscale fusion model, based on the retinal cell photoreceptors model. This paper introduces general prospects of this model, and its application in multispectral medical image fusion. Results showed that the proposed method preserves more spectral features with less spatial distortion. Comparing with hue-intensity-saturation （HIS）, discrete wavelet transform （DWT）, wavelet-based sharpening and wavelet-a trous transform methods, the best spectral and spatial quality is only achieved simultaneously with the proposed feature-based data fusion method. This method does not require resampling images, which is an advantage over the other methods, and can perform in any aspect ratio between the pixels of MRI and PET images.展开更多
The advancement of automated medical diagnosis in biomedical engineering has become an important area of research.Image classification is one of the diagnostic approaches that do not require segmentation which can dra...The advancement of automated medical diagnosis in biomedical engineering has become an important area of research.Image classification is one of the diagnostic approaches that do not require segmentation which can draw quicker inferences.The proposed non-invasive diagnostic support system in this study is considered as an image classification system where the given brain image is classified as normal or abnormal.The ability of deep learning allows a single model for feature extraction as well as classification whereas the rational models require separate models.One of the best models for image localization and classification is the Visual Geometric Group(VGG)model.In this study,an efficient modified VGG architecture for brain image classification is developed using transfer learning.The pooling layer is modified to enhance the classification capability of VGG architecture.Results show that the modified VGG architecture outperforms the conventional VGG architecture with a 5%improvement in classification accuracy using 16 layers on MRI images of the REpository of Molecular BRAin Neoplasia DaTa(REMBRANDT)database.展开更多
Kernel-based clustering is supposed to provide a better analysis tool for pattern classification,which implicitly maps input samples to a highdimensional space for improving pattern separability.For this implicit spac...Kernel-based clustering is supposed to provide a better analysis tool for pattern classification,which implicitly maps input samples to a highdimensional space for improving pattern separability.For this implicit space map,the kernel trick is believed to elegantly tackle the problem of“curse of dimensionality”,which has actually been more challenging for kernel-based clustering in terms of computational complexity and classification accuracy,which traditional kernelized algorithms cannot effectively deal with.In this paper,we propose a novel kernel clustering algorithm,called KFCM-III,for this problem by replacing the traditional isotropic Gaussian kernel with the anisotropic kernel formulated by Mahalanobis distance.Moreover,a reduced-set represented kernelized center has been employed for reducing the computational complexity of KFCM-I algorithm and circumventing the model deficiency of KFCM-II algorithm.The proposed KFCMIII has been evaluated for segmenting magnetic resonance imaging(MRI)images.For this task,an image intensity inhomogeneity correction is employed during image segmentation process.With a scheme called preclassification,the proposed intensity correction scheme could further speed up image segmentation.The experimental results on public image data show the superiorities of KFCM-III.展开更多
Energy metabolism is fundamental for life.It encompasses the utilization of carbohydrates,lipids,and proteins for internal processes,while aberrant energy metabolism is implicated in many diseases.In the present study...Energy metabolism is fundamental for life.It encompasses the utilization of carbohydrates,lipids,and proteins for internal processes,while aberrant energy metabolism is implicated in many diseases.In the present study,using three-dimensional(3D)printing from polycarbonate via fused deposition modeling,we propose a multi-nuclear radiofrequency(RF)coil design with integrated 1H birdcage and interchangeable X-nuclei(^(2)H,^(13)C,^(23)Na,and^(31)P)single-loop coils for magnetic resonance imaging(MRI)/magnetic resonance spectroscopy(MRS).The single-loop coil for each nucleus attaches to an arc bracket that slides unrestrictedly along the birdcage coil inner surface,enabling convenient switching among various nuclei and animal handling.Compared to a commercial 1H birdcage coil,the proposed 1H birdcage coil exhibited superior signal-excitation homogeneity and imaging signal-to-noise ratio(SNR).For X-nuclei study,prominent peaks in spectroscopy for phantom solutions showed excellent SNR,and the static and dynamic peaks of in vivo spectroscopy validated the efficacy of the coil design in structural imaging and energy metabolism detection simultaneously.展开更多
Medical image processing becomes a hot research topic in healthcare sector for effective decision making and diagnoses of diseases.Magnetic resonance imaging(MRI)is a widely utilized tool for the classification and de...Medical image processing becomes a hot research topic in healthcare sector for effective decision making and diagnoses of diseases.Magnetic resonance imaging(MRI)is a widely utilized tool for the classification and detection of prostate cancer.Since the manual screening process of prostate cancer is difficult,automated diagnostic methods become essential.This study develops a novel Deep Learning based Prostate Cancer Classification(DTL-PSCC)model using MRI images.The presented DTL-PSCC technique encompasses EfficientNet based feature extractor for the generation of a set of feature vectors.In addition,the fuzzy k-nearest neighbour(FKNN)model is utilized for classification process where the class labels are allotted to the input MRI images.Moreover,the membership value of the FKNN model can be optimally tuned by the use of krill herd algorithm(KHA)which results in improved classification performance.In order to demonstrate the good classification outcome of the DTL-PSCC technique,a wide range of simulations take place on benchmark MRI datasets.The extensive comparative results ensured the betterment of the DTL-PSCC technique over the recent methods with the maximum accuracy of 85.09%.展开更多
A new method for the denoising,extraction and tumor detection on MRI images is presented in this paper.MRI images help physicians study and diagnose diseases or tumors present in the brain.This work is focused towards...A new method for the denoising,extraction and tumor detection on MRI images is presented in this paper.MRI images help physicians study and diagnose diseases or tumors present in the brain.This work is focused towards helping the radiologist and physician to have a second opinion on the diagnosis.The ambiguity of Magnetic Resonance(MR)image features is solved in a simpler manner.The MRI image acquired from the machine is subjected to analysis in the work.The real-time data is used for the analysis.Basic preprocessing is performed using various filters for noise removal.The de-noised image is segmented,and the feature extractions are performed.Features are extracted using the wavelet transform.When compared to other methods,the wavelet transform is more suitable for MRI image feature extraction.The features are given to the classifier which uses binary tree support vectors for classification.The classification process is compared with conventional methods.展开更多
基金funded by the Deanship of Graduate Studies and Scientific Research at Jouf University under grant No.(DGSSR-2025-02-01295).
文摘Alzheimer’s Disease(AD)is a progressive neurodegenerative disorder that significantly affects cognitive function,making early and accurate diagnosis essential.Traditional Deep Learning(DL)-based approaches often struggle with low-contrast MRI images,class imbalance,and suboptimal feature extraction.This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans.Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization(CLAHE)and Enhanced Super-Resolution Generative Adversarial Networks(ESRGAN).A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient(MCC)-based evaluation method into the design.The trained and validated model gives a 98.88%accuracy rate and 0.9614 MCC score.We also performed a 10-fold cross-validation experiment with an average accuracy of 96.52%(±1.51),a loss of 0.1671,and an MCC score of 0.9429 across folds.The proposed framework outperforms the state-of-the-art models with a 98%weighted F1-score while decreasing misdiagnosis results for every AD stage.The model demonstrates apparent separation abilities between AD progression stages according to the results of the confusion matrix analysis.These results validate the effectiveness of hybrid DL models with adaptive preprocessing for early and reliable Alzheimer’s diagnosis,contributing to improved computer-aided diagnosis(CAD)systems in clinical practice.
文摘The diagnosis of brain tumors is an extended process that significantly depends on the expertise and skills of radiologists.The rise in patient numbers has substantially elevated the data processing volume,making conventional methods both costly and inefficient.Recently,Artificial Intelligence(AI)has gained prominence for developing automated systems that can accurately diagnose or segment brain tumors in a shorter time frame.Many researchers have examined various algorithms that provide both speed and accuracy in detecting and classifying brain tumors.This paper proposes a newmodel based on AI,called the Brain Tumor Detection(BTD)model,based on brain tumor Magnetic Resonance Images(MRIs).The proposed BTC comprises three main modules:(i)Image Processing Module(IPM),(ii)Patient Detection Module(PDM),and(iii)Explainable AI(XAI).In the first module(i.e.,IPM),the used dataset is preprocessed through two stages:feature extraction and feature selection.At first,the MRI is preprocessed,then the images are converted into a set of features using several feature extraction methods:gray level co-occurrencematrix,histogramof oriented gradient,local binary pattern,and Tamura feature.Next,the most effective features are selected fromthese features separately using ImprovedGrayWolfOptimization(IGWO).IGWOis a hybrid methodology that consists of the Filter Selection Step(FSS)using information gain ratio as an initial selection stage and Binary Gray Wolf Optimization(BGWO)to make the proposed method better at detecting tumors by further optimizing and improving the chosen features.Then,these features are fed to PDM using several classifiers,and the final decision is based on weighted majority voting.Finally,through Local Interpretable Model-agnostic Explanations(LIME)XAI,the interpretability and transparency in decision-making processes are provided.The experiments are performed on a publicly available Brain MRI dataset that consists of 98 normal cases and 154 abnormal cases.During the experiments,the dataset was divided into 70%(177 cases)for training and 30%(75 cases)for testing.The numerical findings demonstrate that the BTD model outperforms its competitors in terms of accuracy,precision,recall,and F-measure.It introduces 98.8%accuracy,97%precision,97.5%recall,and 97.2%F-measure.The results demonstrate the potential of the proposed model to revolutionize brain tumor diagnosis,contribute to better treatment strategies,and improve patient outcomes.
基金supported by Gansu Natural Science Foundation Programme(No.24JRRA231)National Natural Science Foundation of China(No.62061023)Gansu Provincial Education,Science and Technology Innovation and Industry(No.2021CYZC-04)。
文摘Brain tumor segmentation is critical in clinical diagnosis and treatment planning.Existing methods for brain tumor segmentation with missing modalities often struggle when dealing with multiple missing modalities,a common scenario in real-world clinical settings.These methods primarily focus on handling a single missing modality at a time,making them insufficiently robust for the additional complexity encountered with incomplete data containing various missing modality combinations.Additionally,most existing methods rely on single models,which may limit their performance and increase the risk of overfitting the training data.This work proposes a novel method called the ensemble adversarial co-training neural network(EACNet)for accurate brain tumor segmentation from multi-modal magnetic resonance imaging(MRI)scans with multiple missing modalities.The proposed method consists of three key modules:the ensemble of pre-trained models,which captures diverse feature representations from the MRI data by employing an ensemble of pre-trained models;adversarial learning,which leverages a competitive training approach involving two models;a generator model,which creates realistic missing data,while sub-networks acting as discriminators learn to distinguish real data from the generated“fake”data.Co-training framework utilizes the information extracted by the multimodal path(trained on complete scans)to guide the learning process in the path handling missing modalities.The model potentially compensates for missing information through co-training interactions by exploiting the relationships between available modalities and the tumor segmentation task.EACNet was evaluated on the BraTS2018 and BraTS2020 challenge datasets and achieved state-of-the-art and competitive performance respectively.Notably,the segmentation results for the whole tumor(WT)dice similarity coefficient(DSC)reached 89.27%,surpassing the performance of existing methods.The analysis suggests that the ensemble approach offers potential benefits,and the adversarial co-training contributes to the increased robustness and accuracy of EACNet for brain tumor segmentation of MRI scans with missing modalities.The experimental results show that EACNet has promising results for the task of brain tumor segmentation of MRI scans with missing modalities and is a better candidate for real-world clinical applications.
基金supported by the Ministry of Higher Education(MOHE)through the Fundamental Research Grant Scheme(FRGS)(FRGS/1/2020/TK0/UTHM/02/16)the Universiti Tun Hussein Onn Malaysia(UTHM)through an FRGS Research Grant(Vot K304).
文摘The automatic localization of the left ventricle(LV)in short-axis magnetic resonance(MR)images is a required step to process cardiac images using convolutional neural networks for the extraction of a region of interest(ROI).The precise extraction of the LV’s ROI from cardiac MRI images is crucial for detecting heart disorders via cardiac segmentation or registration.Nevertheless,this task appears to be intricate due to the diversities in the size and shape of the LV and the scattering of surrounding tissues across different slices.Thus,this study proposed a region-based convolutional network(Faster R-CNN)for the LV localization from short-axis cardiac MRI images using a region proposal network(RPN)integrated with deep feature classification and regression.Themodel was trained using images with corresponding bounding boxes(labels)around the LV,and various experiments were applied to select the appropriate layers and set the suitable hyper-parameters.The experimental findings showthat the proposed modelwas adequate,with accuracy,precision,recall,and F1 score values of 0.91,0.94,0.95,and 0.95,respectively.This model also allows the cropping of the detected area of LV,which is vital in reducing the computational cost and time during segmentation and classification procedures.Therefore,itwould be an ideal model and clinically applicable for diagnosing cardiac diseases.
基金the National Natural Science Foundation of China(No.813716234)the National Basic Research Program(973)of China(No.2010CB834302)Shanghai Jiao Tong University Medical Engineering Cross Research Funds(Nos.YG2013MS30 and YG2014ZD05)
文摘Computed tomography(CT) reconstruction with a well-registered priori magnetic resonance imaging(MRI) image can improve reconstruction results with low-dose CT, because well-registered CT and MRI images have similar structures. However, in clinical settings, the CT image of patients does not always match the priori MRI image because of breathing and movement of patients during CT scanning. To improve the image quality in this case, multi-group datasets expansion is proposed in this paper. In our method, multi-group CT-MRI datasets are formed by expanding CT-MRI datasets. These expanded datasets can also be used by most existing CT-MRI algorithms and improve the reconstructed image quality when the CT image of a patient is not registered with the priori MRI image. In the experiments, we evaluate the performance of the algorithm by using multi-group CT-MRI datasets in several unregistered situations. Experiments show that when the CT and priori MRI images are not registered, the reconstruction results of using multi-group dataset expansion are better than those obtained without using the expansion.
基金the National Natural Science Foundation of China(No.61371017)。
文摘Electrical impedance tomography(EIT)image reconstruction is a non-linear problem.In general,finite element model is the critical basis of EIT image reconstruction.A 3D human thorax modeling method for EIT image reconstruction is proposed herein to improve the accuracy and reduce the complexity of existing finite element modeling methods.The contours of human thorax and lungs are extracted from the layers of magnetic resonance imaging(MRI)images by an optimized Otsu’s method for the construction of the 3D human thorax model including the lung models.Furthermore,the GMSH tool is used for finite element subdivision to generate the 3D finite element model of human thorax.The proposed modeling method is fast and accurate,and it is universal for different types of MRI images.The effectiveness of the proposed method is validated by extensive numerical simulation in MATLAB.The results show that the individually oriented 3D finite element model can improve the reconstruction quality of the EIT images more effectively than the cylindrical model,the 2.5D model and other human chest models.
基金Supported National Natural Science Foundation of China (No.62171321)Tianjin Municipal Natural Science Foundation (No.20JCZDJC00180,19 JCZDJC31500)the Open Projects Program of National Laboratory of Pattern Recognition (No.202000002)。
文摘Attention mechanism combined with convolutional neural network(CNN) achieves promising performance for magnetic resonance imaging(MRI) image segmentation,however these methods only learn attention weights from single scale,resulting in incomplete attention learning.A novel method named completed attention convolutional neural network(CACNN) is proposed for MRI image segmentation.Specifically,the channel-wise attention block(CWAB) and the pixel-wise attention block(PWAB) are designed to learn attention weights from the aspects of channel and pixel levels.As a result,completed attention weights are obtained,which is beneficial to discriminative feature learning.The method is verified on two widely used datasets(HVSMR and MRBrainS),and the experimental results demonstrate that the proposed method achieves better results than the state-of-theart methods.
基金funded by the German Research Foundation(Deutsche Forschungsgemeinschaft,DFG)under project numbers 191948804 and 455548460.
文摘Magnetic resonance imaging(MRI)is one of the most prevalent imaging modalities used for diagnosis,treatment planning,and outcome control in various medical conditions.MRI sequences provide physicians with the ability to view and monitor tissues at multiple contrasts within a single scan and serve as input for automated systems to perform downstream tasks.However,in clinical practice,there is usually no concise set of identically acquired sequences for a whole group of patients.As a consequence,medical professionals and automated systems both face difficulties due to the lack of complementary information from such missing sequences.This problem is well known in computer vision,particularly in medical image processing tasks such as tumor segmentation,tissue classification,and image generation.With the aim of helping researchers,this literature review examines a significant number of recent approaches that attempt to mitigate these problems.Basic techniques such as early synthesis methods,as well as later approaches that deploy deep learning,such as common latent space models,knowledge distillation networks,mutual information maximization,and generative adversarial networks(GANs)are examined in detail.We investigate the novelty,strengths,and weaknesses of the aforementioned strategies.Moreover,using a case study on the segmentation task,our survey offers quantitative benchmarks to further analyze the effectiveness of these methods for addressing the missing modalities challenge.Furthermore,a discussion offers possible future research directions.
文摘Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people everywhere.Due to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the spine.The semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar diseases.It is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation accuracy.This work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra S1.Pseudo-colour mask images were generated and used as ground truth for training the model.The work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar Spine MRI Dataset publicly available from Mendeley Data.The proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DSC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.
基金supported by the National Natural Science Foundation of China(82102018,62333002,T2425027,and 82327809)Data collection and sharing for this project were supported by the National Natural Science Foundation of China(61633018,81571062,81471120,and 81901101)+30 种基金Data collection and sharing for this project were funded by the ADNI(National Institutes of Health Grant U01 AG024904)the Department of Defense ADNI(award number W81XWH-12-2-0012).The ADNI is funded by the National Institute on Aging,the National Institute of Biomedical Imaging and Bioengineering,and through generous contributions from the following:AbbVie,Alzheimer’s AssociationAlzheimer’s Drug Discovery FoundationAraclon BiotechBioClinica,Inc.BiogenBristol-Myers Squibb Co.CereSpir,Inc.CogstateEisai Inc.Elan Pharmaceuticals,Inc.Eli Lilly and Co.EuroImmunF.Hoffmann-La Roche Ltd and its affiliated company Genentech,Inc.FujirebioG.E.HealthcareIXICO Ltd.Janssen Alzheimer Immunotherapy Research&Development,LLC.Johnson&Johnson Pharmaceutical Research&Development LLC.LumosityLundbeckMerck&Co.,Inc.Meso Scale Diagnostics,LLC.NeuroRx ResearchNeurotrack TechnologiesNovartis Pharmaceuticals Corp.Pfizer Inc.Piramal ImagingServierTakeda Pharmaceutical Co.and Transition Therapeutics.The Canadian Institutes of Health Research provides funds to support ADNI clinical sites in Canada.Private sector contributions are facilitated by the Foundation for the National Institutes of Health(www.fnih.org).The grantee organization was the Northern California Institute for Research and Education,and the study was coordinated by the Alzheimer’s Therapeutic Research Institute at the University of Southern California.ADNI data are disseminated by the Laboratory for Neuro Imaging at the University of Southern California.
文摘Dear Editor,Growing clinical evidence shows that brain disorders are heterogeneous in phenotype,genetics,and neuropathology[1].Diagnosis and treatment tend to be affected by symptom presentation and the heterogeneity of pathology,potentially hindering clinical trials in the development of medical treatment.Brain-based subtyping studies utilize magnetic resonance imaging(MRI)and data-driven methods to discover the subtypes of diseases,providing a new perspective on disease heterogeneity.
基金funded by the National Elites Foundation(No.711.5095).
文摘In neuropathological diseases such as Alzheimer's Disease(AD),neuroimaging and Magnetic Resonance Imaging(MRI)play crucial roles in the realm of Artificial Intelligence of Medical Things(AIoMT)by leveraging edge intelligence resources.However,accurately classifying MRI scans based on neurodegenerative diseases faces challenges due to significant variability across classes and limited intra-class differences.To address this challenge,we propose a novel approach aimed at improving the early detection of AD through MRI imaging.This method integrates a Convolutional Neural Network(CNN)with a Cascade Attention Model(CAM-CNN).The CAM-CNN model outperforms traditional CNNs in AD classification accuracy and processing complexity.In this architecture,the attention mechanism is effectively implemented by utilizing two constraint cost functions and a cross-network with diverse pre-trained parameters for a two-stream architecture.Additionally,two new cost functions,Satisfied Rank Loss(SRL)and Cross-Network Similarity Loss(CNSL),are introduced to enhance collaboration and overall network performance.Finally,a unique entropy addition method is employed in the attention module for network integration,converting intermediate outcomes into the final prediction.These components are designed to work collaboratively and can be sequentially trained for optimal performance,thereby enhancing the effectiveness of AD stage classification and robustness to interference from MR images.Validation using the Kaggle dataset demonstrates the model's accuracy of 99.07%in multiclass classification,ensuring precise classification and early detection of all AD subtypes.Further validation across three feature categories with varying numbers confirms the robustness of the proposed approach,with deviations from the standard criteria of less than 1%.Applied in Alzheimer's patient care,this capability holds promise for enhancing value-based therapy and clinical decision-making.It aids in differentiating Alzheimer's patients from healthy individuals,thereby improving patient care and enabling more targeted therapies.
文摘<span style="font-family:Verdana;">Rationale and Objectives: Accurately establishing the diagnosis and staging of cervical and thyroid cancers is essential in medical practice in determining tumor extension and dissemination and involves the most accurate and effective therapeutic approach. For accurate diagnosis and staging of cervical and thyroid cancers, we aim to create a diagnostic method, optimized by the algorithms of artificial intelligence and validated by achieving accurate and favorable results by conducting a clinical trial, during which we will use the diagnostic method optimized by artificial intelligence (AI) algorithms, to avoid errors, to increase the understanding on interpretation computer tomography (CT) scan, magnetic resonance imaging (MRI) of the doctor and improve therapeutic planning. Materials and Methods: The optimization of the computer assisted diagnosis (CAD) method will consist in the development and formation of artificial intelligence models, using algorithms and tools used in segmental volumetric constructions to generate 3D images from MRI/CT. We propose a comparative study of current developments in “DICOM” image processing by volume rendering technique, the use of the transfer function for opacity and color, shades of gray from “DICOM” images projected in a three-dimensional space. We also use artificial intelligence (AI), through the technique of Generative Adversarial Networks (GAN), which has proven to be effective in representing complex data distributions, as we do in this study. Validation of the diagnostic method, optimized by algorithm of artificial intelligence will consist of achieving accurate results on diagnosis and staging of cervical and thyroid cancers by conducting a randomized, controlled clinical trial, for a period of 17 months. Results: We will validate the CAD method through a clinical study and, secondly, we use various network topologies specified above, which have produced promising results in the tasks of image model recognition and by using this mixture. By using this method in medical practice, we aim to avoid errors, provide precision in diagnosing, staging and establishing the therapeutic plan in cancers of the cervix and thyroid using AI. Conclusion: The use of the CAD method can increase the quality of life by avoiding intra and postoperative complications in surgery, intraoperative orientation and the precise determination of radiation doses and irradiation zone in radiotherapy.</span>
基金Ministry of Education,Youth and Sports of the Chezk Republic,Grant/Award Numbers:SP2023/039,SP2023/042the European Union under the REFRESH,Grant/Award Number:CZ.10.03.01/00/22_003/0000048。
文摘Detecting brain tumours is complex due to the natural variation in their location, shape, and intensity in images. While having accurate detection and segmentation of brain tumours would be beneficial, current methods still need to solve this problem despite the numerous available approaches. Precise analysis of Magnetic Resonance Imaging (MRI) is crucial for detecting, segmenting, and classifying brain tumours in medical diagnostics. Magnetic Resonance Imaging is a vital component in medical diagnosis, and it requires precise, efficient, careful, efficient, and reliable image analysis techniques. The authors developed a Deep Learning (DL) fusion model to classify brain tumours reliably. Deep Learning models require large amounts of training data to achieve good results, so the researchers utilised data augmentation techniques to increase the dataset size for training models. VGG16, ResNet50, and convolutional deep belief networks networks extracted deep features from MRI images. Softmax was used as the classifier, and the training set was supplemented with intentionally created MRI images of brain tumours in addition to the genuine ones. The features of two DL models were combined in the proposed model to generate a fusion model, which significantly increased classification accuracy. An openly accessible dataset from the internet was used to test the model's performance, and the experimental results showed that the proposed fusion model achieved a classification accuracy of 98.98%. Finally, the results were compared with existing methods, and the proposed model outperformed them significantly.
基金Project (No. TMU 85-05-33) supported in part by the Iran Telecommunication Research Center (ITRC)
文摘The diagnostic potential of brain positron emission tomography （PET） imaging is limited by low spatial resolution. For solving this problem we propose a technique for the fusion of PET and MRI images. This fusion is a trade-off between the spectral information extracted from PET images and the spatial information extracted from high spatial resolution MRI. The proposed method can control this trade-off. To achieve this goal, it is necessary to build a multiscale fusion model, based on the retinal cell photoreceptors model. This paper introduces general prospects of this model, and its application in multispectral medical image fusion. Results showed that the proposed method preserves more spectral features with less spatial distortion. Comparing with hue-intensity-saturation （HIS）, discrete wavelet transform （DWT）, wavelet-based sharpening and wavelet-a trous transform methods, the best spectral and spatial quality is only achieved simultaneously with the proposed feature-based data fusion method. This method does not require resampling images, which is an advantage over the other methods, and can perform in any aspect ratio between the pixels of MRI and PET images.
文摘The advancement of automated medical diagnosis in biomedical engineering has become an important area of research.Image classification is one of the diagnostic approaches that do not require segmentation which can draw quicker inferences.The proposed non-invasive diagnostic support system in this study is considered as an image classification system where the given brain image is classified as normal or abnormal.The ability of deep learning allows a single model for feature extraction as well as classification whereas the rational models require separate models.One of the best models for image localization and classification is the Visual Geometric Group(VGG)model.In this study,an efficient modified VGG architecture for brain image classification is developed using transfer learning.The pooling layer is modified to enhance the classification capability of VGG architecture.Results show that the modified VGG architecture outperforms the conventional VGG architecture with a 5%improvement in classification accuracy using 16 layers on MRI images of the REpository of Molecular BRAin Neoplasia DaTa(REMBRANDT)database.
基金This work was partially supported by the National Natural Science Foundation of China(Grant Nos.60872145,60902063)the National High Technology Research and Development Program of China(Grant No.2009AA01Z315)+1 种基金the Cultivation Fund of the Key Scientific and Technical Innovation Project,Ministry of Education of China(No.708085)the Henan Research Program of Foundation and Advanced Technology(No.082300410090).
文摘Kernel-based clustering is supposed to provide a better analysis tool for pattern classification,which implicitly maps input samples to a highdimensional space for improving pattern separability.For this implicit space map,the kernel trick is believed to elegantly tackle the problem of“curse of dimensionality”,which has actually been more challenging for kernel-based clustering in terms of computational complexity and classification accuracy,which traditional kernelized algorithms cannot effectively deal with.In this paper,we propose a novel kernel clustering algorithm,called KFCM-III,for this problem by replacing the traditional isotropic Gaussian kernel with the anisotropic kernel formulated by Mahalanobis distance.Moreover,a reduced-set represented kernelized center has been employed for reducing the computational complexity of KFCM-I algorithm and circumventing the model deficiency of KFCM-II algorithm.The proposed KFCMIII has been evaluated for segmenting magnetic resonance imaging(MRI)images.For this task,an image intensity inhomogeneity correction is employed during image segmentation process.With a scheme called preclassification,the proposed intensity correction scheme could further speed up image segmentation.The experimental results on public image data show the superiorities of KFCM-III.
基金This work was supported in part by the STI 2030-Major Projects(No.2021ZD0200401)the National Key Research and Development Program of China(No.2018YFA0701400)+3 种基金the National Natural Science Foundation of China(Nos.52277232,52293424,81701774,and 61771423)the Fundamental Research Funds for the Central Universities(Nos.226-2022-00136 and 226-2023-00125)the Zhejiang Provincial Natural Science Foundation of China(No.LR23E070001),the Key R&D Program of Jiangsu Province(No.BE2022049)the Key-Area R&D Program of Guangdong Province(No.2018B030333001),China.
文摘Energy metabolism is fundamental for life.It encompasses the utilization of carbohydrates,lipids,and proteins for internal processes,while aberrant energy metabolism is implicated in many diseases.In the present study,using three-dimensional(3D)printing from polycarbonate via fused deposition modeling,we propose a multi-nuclear radiofrequency(RF)coil design with integrated 1H birdcage and interchangeable X-nuclei(^(2)H,^(13)C,^(23)Na,and^(31)P)single-loop coils for magnetic resonance imaging(MRI)/magnetic resonance spectroscopy(MRS).The single-loop coil for each nucleus attaches to an arc bracket that slides unrestrictedly along the birdcage coil inner surface,enabling convenient switching among various nuclei and animal handling.Compared to a commercial 1H birdcage coil,the proposed 1H birdcage coil exhibited superior signal-excitation homogeneity and imaging signal-to-noise ratio(SNR).For X-nuclei study,prominent peaks in spectroscopy for phantom solutions showed excellent SNR,and the static and dynamic peaks of in vivo spectroscopy validated the efficacy of the coil design in structural imaging and energy metabolism detection simultaneously.
基金The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work under grant number(RGP 2/25/43)Taif University Researchers Supporting Project Number(TURSP-2020/346),Taif University,Taif,Saudi Arabia.
文摘Medical image processing becomes a hot research topic in healthcare sector for effective decision making and diagnoses of diseases.Magnetic resonance imaging(MRI)is a widely utilized tool for the classification and detection of prostate cancer.Since the manual screening process of prostate cancer is difficult,automated diagnostic methods become essential.This study develops a novel Deep Learning based Prostate Cancer Classification(DTL-PSCC)model using MRI images.The presented DTL-PSCC technique encompasses EfficientNet based feature extractor for the generation of a set of feature vectors.In addition,the fuzzy k-nearest neighbour(FKNN)model is utilized for classification process where the class labels are allotted to the input MRI images.Moreover,the membership value of the FKNN model can be optimally tuned by the use of krill herd algorithm(KHA)which results in improved classification performance.In order to demonstrate the good classification outcome of the DTL-PSCC technique,a wide range of simulations take place on benchmark MRI datasets.The extensive comparative results ensured the betterment of the DTL-PSCC technique over the recent methods with the maximum accuracy of 85.09%.
文摘A new method for the denoising,extraction and tumor detection on MRI images is presented in this paper.MRI images help physicians study and diagnose diseases or tumors present in the brain.This work is focused towards helping the radiologist and physician to have a second opinion on the diagnosis.The ambiguity of Magnetic Resonance(MR)image features is solved in a simpler manner.The MRI image acquired from the machine is subjected to analysis in the work.The real-time data is used for the analysis.Basic preprocessing is performed using various filters for noise removal.The de-noised image is segmented,and the feature extractions are performed.Features are extracted using the wavelet transform.When compared to other methods,the wavelet transform is more suitable for MRI image feature extraction.The features are given to the classifier which uses binary tree support vectors for classification.The classification process is compared with conventional methods.
