The Black-winged Monarch(Monarcha frater)inhabits low-mid elevation forests across New Guinea and far northeastern Australia.Of its four recognized subspecies,M.f.canescens is migratory,breeding in tropical north-east...The Black-winged Monarch(Monarcha frater)inhabits low-mid elevation forests across New Guinea and far northeastern Australia.Of its four recognized subspecies,M.f.canescens is migratory,breeding in tropical north-eastern Australia from approximately November–March.The non-breeding range of M.f.canescens,apart from some individuals overwintering in Australia,has been unknown for>100 years.Data from 194 New Guinean and Australian specimens and a literature review have not solved this mystery;the narrow latitudinal range of the intratropical migration may inhibit use of GPS loggers in resolving the migration route.Field work in central and western parts of southern New Guinea is needed.Specimen data,however,revealed an essentially overlooked population in north-western New Guinea east of the Bird's Head Peninsula phenotypically indistinguishable from nominate M.f.frater of that Peninsula.Future genomic analysis of the complex will be largely done from toepad skin because frozen tissue samples for DNA analysis exist only of four individuals of what we suggest should be elevated to species rank as M.periophthalmicus.We discuss how genomic analysis might distinguish among alternative taxonomic hypotheses of one,two or three species.We suggest English names for what we consider to be three diagnosable taxa worth recognizing at species rank in this group:Arfak Monarch corresponding to M.frater(Bird's Head Peninsula and the“new”population of north-western New Guinea);Pearly Monarch for M.canescens(Australia and still unknown non-breeding range),and Masked Monarch for M.periophthalmicus(including kunupi,elsewhere in New Guinea).展开更多
Analysis of the change in forest cover is important to determine stand dynamics and the processes involved in disturbance and recovery.Forests of the core zone of the Monarch Butterfly Biosphere Reserve were studied u...Analysis of the change in forest cover is important to determine stand dynamics and the processes involved in disturbance and recovery.Forests of the core zone of the Monarch Butterfly Biosphere Reserve were studied using photo interpretation techniques,considering biennial changes between 1999 and 2013 and changes over the whole period of study 1999–2013.Error matrices were elaborated to determine the processes of change involved in both recovery and disturbance.The biennial changes for the whole period amounted to 2274 ha;343 ha accounted as degraded in more than one biennial period.The total changes in forest cover between 1999 and 2013 involved 4902 ha,out of which,2912 ha were affected by disturbance,and 1990 ha were recovered.For density and 2013 vegetation cover maps,the overall accuracy was 95.6%and 90.2%,respectively.By combining both maps,gradual processes were revealed that were not evident in separate analyses.This methodology is useful for the management and conservation of natural protected areas.展开更多
Enterprises have extensively taken on cloud computing environment since it provides on-demand virtualized cloud application resources.The scheduling of the cloud tasks is a well-recognized NP-hard problem.The Task sch...Enterprises have extensively taken on cloud computing environment since it provides on-demand virtualized cloud application resources.The scheduling of the cloud tasks is a well-recognized NP-hard problem.The Task scheduling problem is convoluted while convincing different objectives,which are dispute in nature.In this paper,Multi-Objective Improved Monarch Butterfly Optimization(MOIMBO)algorithm is applied to solve multi-objective task scheduling problems in the cloud in preparation for Pareto optimal solutions.Three different dispute objectives,such as makespan,reliability,and resource utilization,are deliberated for task scheduling problems.The Epsilonfuzzy dominance sort method is utilized in the multi-objective domain to elect the foremost solutions from the Pareto optimal solution set.MOIMBO,together with the Self Adaptive and Greedy Strategies,have been incorporated to enrich the performance of the proposed algorithm.The capability and effectiveness of the proposed algorithm are measured with NSGA-II and MOPSO algorithms.The simulation results prompt that the proposed MOIMBO algorithm extensively diminishes the makespan,maximize the reliability,and guarantees the appropriate resource utilization when associating it with identified existing algorithms.展开更多
As is known to all,the English monarch has existed for a long time in the history which indicates its duration is one of the longest among the royal families in the world.Even after the 48-year English Bourgeois Revol...As is known to all,the English monarch has existed for a long time in the history which indicates its duration is one of the longest among the royal families in the world.Even after the 48-year English Bourgeois Revolution(1640-1688),the English monarch had not been abolished by the English Parliament and its people.And up to now,the United Kingdom of Great Britain and Northern Ireland,which is a developed capitalistic state in the world,still retains its monarch.This paper will particularly introduce the process and the reasons for the monarch’s retention during the English Bourgeois Revolution.展开更多
Scholars have previously attributed the theoretical origin of“the heart is the monarch/ruler”to the monarchical view of politics.However,according to the latest unearthed documents and relevant documents handed down...Scholars have previously attributed the theoretical origin of“the heart is the monarch/ruler”to the monarchical view of politics.However,according to the latest unearthed documents and relevant documents handed down from ancient times,it can be found that the theory of“the heart is the monarch”might derive from the importance of attachment to the“Zhong”ideology in traditional culture,which promoted the concept that the heart as the center of body,should be the ruler and was later evolved as the“monarch”.Similar cognitive views were all mentioned in Confucianism,Taoism,eclectics scholars and other pre-Qin literature,but only in the system of traditional Chinese medicine,they played a significant role in building the heart-centered theory of Zang-Fu.Traditional Chinese medicine is a discipline developed mainly by clinical practice with the fundamental purpose of curing diseases and saving people.Although the philosophy of traditional Chinese medicine(TCM)roots in the pre-Qin Dynasty,the development is unique to the other philosophies.With rich cultural connotations and philosophical thoughts,TCM is certainly the key to the treasures of Chinese civilization and deserves more attention and exploration.展开更多
Background:In the interim analysis of MONARCH plus,adding abemaciclib to endocrine therapy(ET)improved progression-free survival(PFS)and objective response rate(ORR)in predominantly Chinese postmenopausal women with H...Background:In the interim analysis of MONARCH plus,adding abemaciclib to endocrine therapy(ET)improved progression-free survival(PFS)and objective response rate(ORR)in predominantly Chinese postmenopausal women with HR+/HER2-advanced breast cancer(ABC).This study presents the final pre-planned PFS analysis.Methods:In the phase III MONARCH plus study,postmenopausal women in China,India,Brazil,and South Africa with HR+/HER2-ABC without prior systemic therapy in an advanced setting(cohort A)or progression on prior ET(cohort B)were randomized(2:1)to abemaciclib(150 mg twice daily[BID])or placebo plus:anastrozole(1.0 mg/day)or letrozole(2.5 mg/day)(cohort A)or fulvestrant(500 mg on days 1 and 15 of cycle 1 and then on day 1 of each subsequent cycle)(cohort B).The primary endpoint was PFS of cohort A.Secondary endpoints included cohort B PFS(key secondary endpoint),ORR,overall survival(OS),safety,and health-related quality of life(HRQoL).Results:In cohort A(abemaciclib:n=207;placebo:n=99),abemaciclib plus a non-steroidal aromatase inhibitor improved median PFS vs.placebo(28.27 months vs.14.73 months,hazard ratio[HR]:0.476;95%confidence interval[95%CI]:0.348-0.649).In cohort B(abemaciclib:n=104;placebo:n=53),abemaciclib plus fulvestrant improved median PFS vs.placebo(11.41 months vs.5.59 months,HR:0.480;95%CI:0.322-0.715).Abemaciclib numerically improved ORR.Although immature,a trend toward OS benefit with abemaciclib was observed(cohort A:HR:0.893,95%CI:0.553-1.443;cohort B:HR:0.512,95%CI:0.281-0.931).The most frequent grade≥3 adverse events in the abemaciclib arms were neutropenia,leukopenia,anemia(both cohorts),and lymphocytopenia(cohort B).Abemaciclib did not cause clinically meaningful changes in patient-reported global health,functioning,or most symptoms vs.placebo.Conclusions:Abemaciclib plus ET led to improvements in PFS and ORR,a manageable safety profile,and sustained HRQoL,providing clinical benefit without a high toxicity burden or reduced quality of life.展开更多
文摘The Black-winged Monarch(Monarcha frater)inhabits low-mid elevation forests across New Guinea and far northeastern Australia.Of its four recognized subspecies,M.f.canescens is migratory,breeding in tropical north-eastern Australia from approximately November–March.The non-breeding range of M.f.canescens,apart from some individuals overwintering in Australia,has been unknown for>100 years.Data from 194 New Guinean and Australian specimens and a literature review have not solved this mystery;the narrow latitudinal range of the intratropical migration may inhibit use of GPS loggers in resolving the migration route.Field work in central and western parts of southern New Guinea is needed.Specimen data,however,revealed an essentially overlooked population in north-western New Guinea east of the Bird's Head Peninsula phenotypically indistinguishable from nominate M.f.frater of that Peninsula.Future genomic analysis of the complex will be largely done from toepad skin because frozen tissue samples for DNA analysis exist only of four individuals of what we suggest should be elevated to species rank as M.periophthalmicus.We discuss how genomic analysis might distinguish among alternative taxonomic hypotheses of one,two or three species.We suggest English names for what we consider to be three diagnosable taxa worth recognizing at species rank in this group:Arfak Monarch corresponding to M.frater(Bird's Head Peninsula and the“new”population of north-western New Guinea);Pearly Monarch for M.canescens(Australia and still unknown non-breeding range),and Masked Monarch for M.periophthalmicus(including kunupi,elsewhere in New Guinea).
基金funded by CONACYT and DGAPA within the sabbatical abroad program for the consolidation of research groups“Dynamics of deforestation,forest degradation and recovery in the Monarch Butterfly Biosphere Reserve”。
文摘Analysis of the change in forest cover is important to determine stand dynamics and the processes involved in disturbance and recovery.Forests of the core zone of the Monarch Butterfly Biosphere Reserve were studied using photo interpretation techniques,considering biennial changes between 1999 and 2013 and changes over the whole period of study 1999–2013.Error matrices were elaborated to determine the processes of change involved in both recovery and disturbance.The biennial changes for the whole period amounted to 2274 ha;343 ha accounted as degraded in more than one biennial period.The total changes in forest cover between 1999 and 2013 involved 4902 ha,out of which,2912 ha were affected by disturbance,and 1990 ha were recovered.For density and 2013 vegetation cover maps,the overall accuracy was 95.6%and 90.2%,respectively.By combining both maps,gradual processes were revealed that were not evident in separate analyses.This methodology is useful for the management and conservation of natural protected areas.
文摘Enterprises have extensively taken on cloud computing environment since it provides on-demand virtualized cloud application resources.The scheduling of the cloud tasks is a well-recognized NP-hard problem.The Task scheduling problem is convoluted while convincing different objectives,which are dispute in nature.In this paper,Multi-Objective Improved Monarch Butterfly Optimization(MOIMBO)algorithm is applied to solve multi-objective task scheduling problems in the cloud in preparation for Pareto optimal solutions.Three different dispute objectives,such as makespan,reliability,and resource utilization,are deliberated for task scheduling problems.The Epsilonfuzzy dominance sort method is utilized in the multi-objective domain to elect the foremost solutions from the Pareto optimal solution set.MOIMBO,together with the Self Adaptive and Greedy Strategies,have been incorporated to enrich the performance of the proposed algorithm.The capability and effectiveness of the proposed algorithm are measured with NSGA-II and MOPSO algorithms.The simulation results prompt that the proposed MOIMBO algorithm extensively diminishes the makespan,maximize the reliability,and guarantees the appropriate resource utilization when associating it with identified existing algorithms.
文摘As is known to all,the English monarch has existed for a long time in the history which indicates its duration is one of the longest among the royal families in the world.Even after the 48-year English Bourgeois Revolution(1640-1688),the English monarch had not been abolished by the English Parliament and its people.And up to now,the United Kingdom of Great Britain and Northern Ireland,which is a developed capitalistic state in the world,still retains its monarch.This paper will particularly introduce the process and the reasons for the monarch’s retention during the English Bourgeois Revolution.
文摘Scholars have previously attributed the theoretical origin of“the heart is the monarch/ruler”to the monarchical view of politics.However,according to the latest unearthed documents and relevant documents handed down from ancient times,it can be found that the theory of“the heart is the monarch”might derive from the importance of attachment to the“Zhong”ideology in traditional culture,which promoted the concept that the heart as the center of body,should be the ruler and was later evolved as the“monarch”.Similar cognitive views were all mentioned in Confucianism,Taoism,eclectics scholars and other pre-Qin literature,but only in the system of traditional Chinese medicine,they played a significant role in building the heart-centered theory of Zang-Fu.Traditional Chinese medicine is a discipline developed mainly by clinical practice with the fundamental purpose of curing diseases and saving people.Although the philosophy of traditional Chinese medicine(TCM)roots in the pre-Qin Dynasty,the development is unique to the other philosophies.With rich cultural connotations and philosophical thoughts,TCM is certainly the key to the treasures of Chinese civilization and deserves more attention and exploration.
文摘Background:In the interim analysis of MONARCH plus,adding abemaciclib to endocrine therapy(ET)improved progression-free survival(PFS)and objective response rate(ORR)in predominantly Chinese postmenopausal women with HR+/HER2-advanced breast cancer(ABC).This study presents the final pre-planned PFS analysis.Methods:In the phase III MONARCH plus study,postmenopausal women in China,India,Brazil,and South Africa with HR+/HER2-ABC without prior systemic therapy in an advanced setting(cohort A)or progression on prior ET(cohort B)were randomized(2:1)to abemaciclib(150 mg twice daily[BID])or placebo plus:anastrozole(1.0 mg/day)or letrozole(2.5 mg/day)(cohort A)or fulvestrant(500 mg on days 1 and 15 of cycle 1 and then on day 1 of each subsequent cycle)(cohort B).The primary endpoint was PFS of cohort A.Secondary endpoints included cohort B PFS(key secondary endpoint),ORR,overall survival(OS),safety,and health-related quality of life(HRQoL).Results:In cohort A(abemaciclib:n=207;placebo:n=99),abemaciclib plus a non-steroidal aromatase inhibitor improved median PFS vs.placebo(28.27 months vs.14.73 months,hazard ratio[HR]:0.476;95%confidence interval[95%CI]:0.348-0.649).In cohort B(abemaciclib:n=104;placebo:n=53),abemaciclib plus fulvestrant improved median PFS vs.placebo(11.41 months vs.5.59 months,HR:0.480;95%CI:0.322-0.715).Abemaciclib numerically improved ORR.Although immature,a trend toward OS benefit with abemaciclib was observed(cohort A:HR:0.893,95%CI:0.553-1.443;cohort B:HR:0.512,95%CI:0.281-0.931).The most frequent grade≥3 adverse events in the abemaciclib arms were neutropenia,leukopenia,anemia(both cohorts),and lymphocytopenia(cohort B).Abemaciclib did not cause clinically meaningful changes in patient-reported global health,functioning,or most symptoms vs.placebo.Conclusions:Abemaciclib plus ET led to improvements in PFS and ORR,a manageable safety profile,and sustained HRQoL,providing clinical benefit without a high toxicity burden or reduced quality of life.
