To enhance the utilization of pesticides and reduce environmental risks,we constructed the magnetic recyclable and dual stimulus-responsive microspheres to achieve on-demand pesticide release.Magnetic multi-shell holl...To enhance the utilization of pesticides and reduce environmental risks,we constructed the magnetic recyclable and dual stimulus-responsive microspheres to achieve on-demand pesticide release.Magnetic multi-shell hollow mesoporous organosilicon nanoparticles(mMSN)were prepared by one-step hydrothermal method and loaded with pesticide avermectin(A@mMSN),afterward A@mMSN was coated with gelatin through emulsification and chemical cross-linking to prepare A@mMSN@G microspheres(21.5±9.7μm).After being absorbed by the pests,the gelatin layer was hydrolyzed with the neutral protease,and the disulfide bonds within mMSN framework were decomposed by glutathione(GSH),endowing A@mMSN@G microspheres with enzyme and GSH responsiveness to achieve sustained avermectin release till 7 days(about 3.5 times that of the commercial avermectin emulsion).Importantly,the A@mMSN@G microspheres containing Fe3O4 nanoparticles could be easily magnetically collected from soil with a recovery ratio of 63.7%,to reduce the environmental risks.With excellent biosafety,A@mMSN@G microspheres showed outstanding pest control effects till two weeks and the growth of cabbage was not affected by it.Therefore,based on the recyclability and dual stimulus-responsive controllable release,the fabricated A@mMSN@G microspheres have broad application potential in pesticide delivery.展开更多
基金supported by the Guangzhou Science and Technology Program Project(No.202206010187 and 2023B03J1332)the National Natural Science Foundation of China(No.22208115)+1 种基金the Fundamental Research Funds for the Central Universities(No.2023ZYGXZR041)the Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001).
文摘To enhance the utilization of pesticides and reduce environmental risks,we constructed the magnetic recyclable and dual stimulus-responsive microspheres to achieve on-demand pesticide release.Magnetic multi-shell hollow mesoporous organosilicon nanoparticles(mMSN)were prepared by one-step hydrothermal method and loaded with pesticide avermectin(A@mMSN),afterward A@mMSN was coated with gelatin through emulsification and chemical cross-linking to prepare A@mMSN@G microspheres(21.5±9.7μm).After being absorbed by the pests,the gelatin layer was hydrolyzed with the neutral protease,and the disulfide bonds within mMSN framework were decomposed by glutathione(GSH),endowing A@mMSN@G microspheres with enzyme and GSH responsiveness to achieve sustained avermectin release till 7 days(about 3.5 times that of the commercial avermectin emulsion).Importantly,the A@mMSN@G microspheres containing Fe3O4 nanoparticles could be easily magnetically collected from soil with a recovery ratio of 63.7%,to reduce the environmental risks.With excellent biosafety,A@mMSN@G microspheres showed outstanding pest control effects till two weeks and the growth of cabbage was not affected by it.Therefore,based on the recyclability and dual stimulus-responsive controllable release,the fabricated A@mMSN@G microspheres have broad application potential in pesticide delivery.
