Objective： To investigate the clinical effects of electroacupuncture （EA） on the head points for improving gnosia in patients with vascular dementia （VD）. Methods： 90 VD patients were randomly divided into a dru...Objective： To investigate the clinical effects of electroacupuncture （EA） on the head points for improving gnosia in patients with vascular dementia （VD）. Methods： 90 VD patients were randomly divided into a drug group, an EA group and an EA plus drug group. Scoring with the M/VISE scale and detecting the relevant potentials were done before treatment and after a 6-week treatment. Results： Gnosia was improved after treatment in all the three groups with no significant difference by the intergroup comparison. Conclusion： The above three therapies can all improve gnosia, reduce the psychological stress, strengthen attention and shorten the awaiting time for recognition; and EA plus Nimodipine seems to be the best in the curative effect.展开更多
目的评价多奈哌齐联合阿托伐他汀对老年血管性认知功能障碍(VCI)患者的临床疗效。方法将69例确诊VCI的老年患者随机分为多奈哌齐联合阿托伐他汀组(治疗组,35例)和多奈哌齐组(对照组,34例),2组接受常规药物治疗。2组患者于始疗前、治疗...目的评价多奈哌齐联合阿托伐他汀对老年血管性认知功能障碍(VCI)患者的临床疗效。方法将69例确诊VCI的老年患者随机分为多奈哌齐联合阿托伐他汀组(治疗组,35例)和多奈哌齐组(对照组,34例),2组接受常规药物治疗。2组患者于始疗前、治疗第12和24周分别行经颅多普勒(TCD)检查颅内主要动脉的搏动指数(PI)、阻力指数(RI),并进行简易精神状态检查量表(Mini-Mental State Examination,MMSE)和日常生活能力量表(ADL)评分,再进行统计分析。结果治疗第12周治疗组和对照组MMSE评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.05);2组间MMSE评分比较,差异无统计学意义(P>0.05)。治疗第24周治疗组和对照组MMSE评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.01);2组间MMSE评分比较,差异有统计学意义P<0.05)。治疗第12周治疗组和对照组ADL评分与治疗前比较,差异均有统计学意义(P<0.05、P<0.05);2组间ADL评分比较,差异无统计学意义(P>0.05)。治疗第24周治疗组与对照组ADL评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.05);2组间ADL评分比较,差异有统计学意义(P<0.01)。治疗第12周治疗组脑动脉PI值与对照组比较,差异均无统计学意义(P>0.05);治疗第24周治疗组各脑动脉PI值与治疗前及第24周对照组PI值比较,差异均有统计学意义(P<0.05)。治疗12周后治疗组脑动脉RI值与对照组比较,差异无统计学意义(P>0.05);治疗24周后治疗组各脑动脉RI值与治疗前及第24周对照组比较,差异均有统计学意义(P<0.05、P<0.05)。结论多奈哌齐能改善VCI患者的认知功能;多奈哌齐联合阿托伐他汀能更好地改善VCI患者的认知功能,提高生活质量。展开更多
文摘Objective： To investigate the clinical effects of electroacupuncture （EA） on the head points for improving gnosia in patients with vascular dementia （VD）. Methods： 90 VD patients were randomly divided into a drug group, an EA group and an EA plus drug group. Scoring with the M/VISE scale and detecting the relevant potentials were done before treatment and after a 6-week treatment. Results： Gnosia was improved after treatment in all the three groups with no significant difference by the intergroup comparison. Conclusion： The above three therapies can all improve gnosia, reduce the psychological stress, strengthen attention and shorten the awaiting time for recognition; and EA plus Nimodipine seems to be the best in the curative effect.
文摘目的评价多奈哌齐联合阿托伐他汀对老年血管性认知功能障碍(VCI)患者的临床疗效。方法将69例确诊VCI的老年患者随机分为多奈哌齐联合阿托伐他汀组(治疗组,35例)和多奈哌齐组(对照组,34例),2组接受常规药物治疗。2组患者于始疗前、治疗第12和24周分别行经颅多普勒(TCD)检查颅内主要动脉的搏动指数(PI)、阻力指数(RI),并进行简易精神状态检查量表(Mini-Mental State Examination,MMSE)和日常生活能力量表(ADL)评分,再进行统计分析。结果治疗第12周治疗组和对照组MMSE评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.05);2组间MMSE评分比较,差异无统计学意义(P>0.05)。治疗第24周治疗组和对照组MMSE评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.01);2组间MMSE评分比较,差异有统计学意义P<0.05)。治疗第12周治疗组和对照组ADL评分与治疗前比较,差异均有统计学意义(P<0.05、P<0.05);2组间ADL评分比较,差异无统计学意义(P>0.05)。治疗第24周治疗组与对照组ADL评分与治疗前比较,差异均有统计学意义(P<0.01、P<0.05);2组间ADL评分比较,差异有统计学意义(P<0.01)。治疗第12周治疗组脑动脉PI值与对照组比较,差异均无统计学意义(P>0.05);治疗第24周治疗组各脑动脉PI值与治疗前及第24周对照组PI值比较,差异均有统计学意义(P<0.05)。治疗12周后治疗组脑动脉RI值与对照组比较,差异无统计学意义(P>0.05);治疗24周后治疗组各脑动脉RI值与治疗前及第24周对照组比较,差异均有统计学意义(P<0.05、P<0.05)。结论多奈哌齐能改善VCI患者的认知功能;多奈哌齐联合阿托伐他汀能更好地改善VCI患者的认知功能,提高生活质量。
