The paper aims to research on online mind map as interface of learning resource integration and sharing.We developed a web application that provides a interface to allow users to create a knowledge mind map.With the o...The paper aims to research on online mind map as interface of learning resource integration and sharing.We developed a web application that provides a interface to allow users to create a knowledge mind map.With the online mind mapping tool,the electronic learning resource will be discovered and shared in the form of subject-oriented package,it is more flexibly than the other E-Learning systems,and the interaction and cooperation of the users are strengthened to some extent.展开更多
The prognosis of CD20-positive (CD20+) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) recurrence is still poor. A standard treatment for CD20+ DLBCL with CNS recurrence in elderly patients has...The prognosis of CD20-positive (CD20+) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) recurrence is still poor. A standard treatment for CD20+ DLBCL with CNS recurrence in elderly patients has not been established mainly due to adverse effects. We previously reported the efficacy and safety of MIND-E (ranimustine, ifosfamide, procarbazine, dexamethasone, and etoposide) therapy for elderly CD20+ DLBCL patients with CNS recurrence. Here, we report the use of R-MIND-E therapy (rituximab, ranimustine, ifosfamide, procarbazine, dexamethasone and etoposide) in an elderly CD20+ DLBCL patient with CNS recurrence. The patient achieved a complete response according to Revised Response Criteria for Malignant Lymphoma, and treatment-related toxicity was tolerable. R-MIND-E therapy may be a feasible and useful treatment option for elderly CD20+ DLBCL patients with CNS recurrence.展开更多
基金the Innovation Program of Shanghai Municipal Education Commission(No.12ZZ060)the National Textile and Apparel Council Project of China(No.2011-10255-7)
文摘The paper aims to research on online mind map as interface of learning resource integration and sharing.We developed a web application that provides a interface to allow users to create a knowledge mind map.With the online mind mapping tool,the electronic learning resource will be discovered and shared in the form of subject-oriented package,it is more flexibly than the other E-Learning systems,and the interaction and cooperation of the users are strengthened to some extent.
文摘The prognosis of CD20-positive (CD20+) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) recurrence is still poor. A standard treatment for CD20+ DLBCL with CNS recurrence in elderly patients has not been established mainly due to adverse effects. We previously reported the efficacy and safety of MIND-E (ranimustine, ifosfamide, procarbazine, dexamethasone, and etoposide) therapy for elderly CD20+ DLBCL patients with CNS recurrence. Here, we report the use of R-MIND-E therapy (rituximab, ranimustine, ifosfamide, procarbazine, dexamethasone and etoposide) in an elderly CD20+ DLBCL patient with CNS recurrence. The patient achieved a complete response according to Revised Response Criteria for Malignant Lymphoma, and treatment-related toxicity was tolerable. R-MIND-E therapy may be a feasible and useful treatment option for elderly CD20+ DLBCL patients with CNS recurrence.
