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Mhem/M(Hb)型巨噬细胞极化在动脉粥样硬化病变中的作用 被引量:1
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作者 罗之晟 王超 +1 位作者 刘家汝 关秀茹 《心血管病学进展》 CAS 2021年第12期1120-1123,共4页
动脉粥样硬化是一种脂质驱动、炎症性的慢性疾病。巨噬细胞极化是动脉粥样硬化形成、进展的重要参与者与潜在治疗靶点。Mhem/M(Hb)型巨噬细胞[Mhem/M(Hb)]是一种出血相关的巨噬细胞亚群,现就Mhem/M(Hb)的自身特点及其在斑块中的来源发... 动脉粥样硬化是一种脂质驱动、炎症性的慢性疾病。巨噬细胞极化是动脉粥样硬化形成、进展的重要参与者与潜在治疗靶点。Mhem/M(Hb)型巨噬细胞[Mhem/M(Hb)]是一种出血相关的巨噬细胞亚群,现就Mhem/M(Hb)的自身特点及其在斑块中的来源发展进行介绍,探究Mhem/M(Hb)在斑块中发挥的作用以及相应的分子机制和信号通路,为抗动脉粥样硬化治疗寻找新的策略和靶点。 展开更多
关键词 动脉粥样硬化 巨噬细胞极化 mhem/M(Hb)
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A MODIFIED HYBRID ELEMENT MODEL FOR COMBINED DIFFRACTION-REFRACTION-REFLECTION-DISSIPATION WAVES OVER LARGE REGIONS 被引量:2
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作者 张黎邦 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 1996年第1期68-78,共11页
A modified hybrid element method (MHEM) including diffraction, refraction, reflection and dissipa-tion effects is developed to model wave transformation over large complex bathymetry under practical bo-undary conditio... A modified hybrid element method (MHEM) including diffraction, refraction, reflection and dissipa-tion effects is developed to model wave transformation over large complex bathymetry under practical bo-undary conditions. Adoption of a simple functional in the MHEM dispenses with the additional unknownsin simultaneous equations of the conventional hybrid element method (HEM). In this paper incompleteCholeski & conjugate gradients (ICCG) algorithm is used to save computer CPU operation time and storagespace; so calculation of wave information in large an area can be carried out on PC computers. Also, theMHEM grid can be controlled by computer using local wavelength. The validity and efficiency of MHEM areconfirmed by comparisons verifying that the MHEM can proviide numerical solutions with very good accuracy. 展开更多
关键词 mhem ICCG algorithm WAVE information
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