母乳是一种适应后代需求、特质成分丰富的乳液,直接影响婴儿的生长发育。母乳成分包括三大营养素(蛋白质、脂肪和碳水化合物)、矿物质、维生素以及各种生物活性物质等。在对母乳成分不断的探究中,最新研究发现人乳中可杀死肿瘤细胞的人...母乳是一种适应后代需求、特质成分丰富的乳液,直接影响婴儿的生长发育。母乳成分包括三大营养素(蛋白质、脂肪和碳水化合物)、矿物质、维生素以及各种生物活性物质等。在对母乳成分不断的探究中,最新研究发现人乳中可杀死肿瘤细胞的人α-乳清蛋白(humanα-lactalbumin made lethal to tumor cells,HAMLET);乳脂球膜(milk fat globule membrane,MFGM)对婴儿免疫系统发育和肠道健康有所帮助,更加证实了人乳的不可替代性。人乳成分的研究为母乳喂养及疾病研究提供了依据并具有指导意义。展开更多
Milk fat globule membrane (MFGM) phospholipids-based nanostructures were developed and their functionalization with rhamnolipids (RLs) was carried out to enhance the preservation of cheese against resistant foodborne ...Milk fat globule membrane (MFGM) phospholipids-based nanostructures were developed and their functionalization with rhamnolipids (RLs) was carried out to enhance the preservation of cheese against resistant foodborne pathogens i.e.,Listeria monocytogenes and Escherichia coli .Void (without nisin) and nisin-loaded RLs functionalized MFGM nanostructures (RLs-MFGM-NS) were fabricated by ultrasonication-assisted self-assembly method.Cubic morphology of void and loaded RLs-MFGM-NS and pristine MFGM nanostructures (MFGM-NS) was observed under scanning electron microscopy (SEM),which indicated uniform size ranging from 43 nm (void RLs-MFGM-NS) to 194 nm (loaded RLs-MFGM-NS).FTIR analyses confirmed the electrostatic interaction,predominantly H-bonding and linkage of carboxyl ester group of MFGM with C–H group in RLs after functionalization of NS.Furthermore,quantitative antimicrobial assay on cheese slices confirmed the broad-spectrum potential of intrinsically active nanostructures (due to RLs) having synergistic activity with nisin against L.monocytogenes and E.coli .Hence,nisin-loaded RLs-MFGM-NS can be applied as promising bioactive additives for sustained preservation of cheese.展开更多
文摘母乳是一种适应后代需求、特质成分丰富的乳液,直接影响婴儿的生长发育。母乳成分包括三大营养素(蛋白质、脂肪和碳水化合物)、矿物质、维生素以及各种生物活性物质等。在对母乳成分不断的探究中,最新研究发现人乳中可杀死肿瘤细胞的人α-乳清蛋白(humanα-lactalbumin made lethal to tumor cells,HAMLET);乳脂球膜(milk fat globule membrane,MFGM)对婴儿免疫系统发育和肠道健康有所帮助,更加证实了人乳的不可替代性。人乳成分的研究为母乳喂养及疾病研究提供了依据并具有指导意义。
基金grateful to Higher Education Commission(HEC),Pakistan for funding under the National Research Program for Universities(NRPU)Vide Grant No.5378.
文摘Milk fat globule membrane (MFGM) phospholipids-based nanostructures were developed and their functionalization with rhamnolipids (RLs) was carried out to enhance the preservation of cheese against resistant foodborne pathogens i.e.,Listeria monocytogenes and Escherichia coli .Void (without nisin) and nisin-loaded RLs functionalized MFGM nanostructures (RLs-MFGM-NS) were fabricated by ultrasonication-assisted self-assembly method.Cubic morphology of void and loaded RLs-MFGM-NS and pristine MFGM nanostructures (MFGM-NS) was observed under scanning electron microscopy (SEM),which indicated uniform size ranging from 43 nm (void RLs-MFGM-NS) to 194 nm (loaded RLs-MFGM-NS).FTIR analyses confirmed the electrostatic interaction,predominantly H-bonding and linkage of carboxyl ester group of MFGM with C–H group in RLs after functionalization of NS.Furthermore,quantitative antimicrobial assay on cheese slices confirmed the broad-spectrum potential of intrinsically active nanostructures (due to RLs) having synergistic activity with nisin against L.monocytogenes and E.coli .Hence,nisin-loaded RLs-MFGM-NS can be applied as promising bioactive additives for sustained preservation of cheese.
