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Malagasy生物碱的合成研究进展
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作者 何卫刚 刘亚东 +1 位作者 邓迎开 孙先宇 《有机化学》 北大核心 2025年第4期1153-1165,共13页
Malagasy生物碱具有特征的反式稠合C/D环系以及多个连续手性中心,为其合成研究带来了巨大挑战.此类生物碱还具有潜在的抗疟增效活性,尤其是malagashanine作为天然增敏剂,可以提升耐药疟原虫对于氯喹的敏感性.独特而极具挑战性的结构以... Malagasy生物碱具有特征的反式稠合C/D环系以及多个连续手性中心,为其合成研究带来了巨大挑战.此类生物碱还具有潜在的抗疟增效活性,尤其是malagashanine作为天然增敏剂,可以提升耐药疟原虫对于氯喹的敏感性.独特而极具挑战性的结构以及明确的药理活性,使得此类天然产物的合成研究颇具吸引力,同时对于新型抗疟药物的研发也具有重要价值.本综述总结了目前Malagasy生物碱的合成研究进展,包括半合成研究、核心骨架构建以及全合成研究. 展开更多
关键词 malagasy生物碱 全合成 骨架构建 半合成 抗疟活性
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Carcass Traits of the Malagasy Zebu "Bos taurus indicus" (Linnaeus, 1758)
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作者 Rivo Nirina Rabearimisa Zo Harinoro Rabenirina Isabelle Herisoa Hantanirina Arsene Randrianariveloseheno Jean de Neupomuscene Rakotozandriny 《Journal of Environmental Science and Engineering(A)》 2015年第11期578-586,共9页
Improving Malagasy zebu production in the face of booming Malagasy population and regression of the animal number, this study was initiated to put forth some Malagasy zebu carcass weight performance and dressing perce... Improving Malagasy zebu production in the face of booming Malagasy population and regression of the animal number, this study was initiated to put forth some Malagasy zebu carcass weight performance and dressing percentages following slaughter. Measurements concerned live weight before slaughtering, carcass weights, quarters and carcass halves, left and right and the fiffla quarter (blood, leather, intestine, lung, heart, liver, kidneys, spleen and rumen with its content) weights on 544 individuals without distinction (age nor sex). Descriptive statistical analysis was undertaken to qualify and compare the various weights. It results high proportion females (66%), smaller size (live weight less than 250 kg, 60%) and 5 live weight classes. Live weight was different in the 2 sexes starting class 3 (live weight 〉 250 kg) (p = 0.0027). Males fore quarters were heavier than females (p 〈 1‰). Carcass dressing percentage increased according to live weight class, whereas, 5th quarter yield presented a regressive reduction with increasing weight class. Survey shows an average dressing percentage of 46.20% with an average 5th quarter yield of 37.43%. Malagasy zebus are light weighted animals compared to the African zebus. Precocious slaughtering (before 250 kg live weight) doesn't allow a good meat yield. 展开更多
关键词 Beef cattle malagasy zebu extensive raising system carcass traits dressing percentage ratios quarter weight/live weight.
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NEW STRATEGIES FOR THE CONTROL OF BACTERIAL INFECTIONS: MODULATORS OF QUORUM SENSING AND BIOFILM FORMATION FROM MALAGASY DALBERGIA SPECIES
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作者 Tsiry Rasamiravaka Pierre Duez Mondher El Jaziri 《World Journal of Traditional Chinese Medicine》 2015年第4期83-83,共1页
Considering the WHO warning about the emergence of a’post-antibiotic’era during the 21st century in which common infections and minor injuries will have a dramatic impact on human death toll,search for new potential... Considering the WHO warning about the emergence of a’post-antibiotic’era during the 21st century in which common infections and minor injuries will have a dramatic impact on human death toll,search for new potential antibacterial drug targets became a necessary need.Targets that are extensively explored concern the modulation 展开更多
关键词 QS MODULATORS OF QUORUM SENSING AND BIOFILM FORMATION FROM malagasy DALBERGIA SPECIES NEW STRATEGIES FOR THE CONTROL OF BACTERIAL INFECTIONS
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Characteristics and potential analysis of Madagascar hydrocarbon-bearing basins 被引量:2
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作者 Da-tian Wu Johanne Iomimalala Ramaniraka +4 位作者 Feng-ming Xu Jian-bo Shao Yong-heng Zhou Yuan-dong Zhao Bruno Ralison 《China Geology》 2019年第1期56-66,共11页
Madagascar becomes a large isolated island after its dislocation from East Africa at its western part during the opening of the Mozambique Channel and its separation from India at its eastern part during the opening o... Madagascar becomes a large isolated island after its dislocation from East Africa at its western part during the opening of the Mozambique Channel and its separation from India at its eastern part during the opening of the basin of the Mascarene. From a stratigraphic point of view, Karroo of Madagascar shares substantial similarities with the stratigraphic strata of East Africa.While oil companies have taken a liking to the basins of East Africa, they also turn to the basins in the western part of Madagascar especially after the discovery of large oil fields at Tsimiroro and Bemolanga. According to the study of their geological history, the basins of Madagascar contain huge hydrocarbon potential. The western basins, which is more developed than the east coast of the island, have been the subject of many in-depth studies by numerous researchers. The cross-referencing of bibliographic data with geological studies, and knowledge of hydrocarbon formation and maturation stages, carried out in this study served to determine the nature of source rocks, reservoir rocks, bedrock and eventual trapping system of hydrocarbons in Madagascar. This study identified the properties of Madagascar source rocks, reservoir rocks, bedrock and the final oil and gas trap system by cross-referencing the literature and geological research, oil and gas formation and maturity stages, and shows that Madagascar has considerable hydrocarbon potential. 展开更多
关键词 Madagascar Hydrocarbon-bearing BASINS CHARACTERISTICS of malagasy BASINS Potential analysis Geology and STRATIGRAPHY
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The Mangroves of the East of Madagascar: Ecological Potentials and Pressures
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作者 Andriamparany Rakotomavo 《Open Journal of Ecology》 2018年第8期447-458,共12页
With 213,000 ha of remaining mangroves in 2016, Madagascar has about 4260 ha of mangrove on its Eastern coast. The purpose of this article is to provide essential data on the spatial distribution of this ecosystem of ... With 213,000 ha of remaining mangroves in 2016, Madagascar has about 4260 ha of mangrove on its Eastern coast. The purpose of this article is to provide essential data on the spatial distribution of this ecosystem of Eastern Madagascar, its ecological potentials and the pressures on its resources. Five Eastern Mangrove sites were selected, from South to North, because of their accessibility and their spatial position: Foulpointe, Sainte Marie, Manompana, Mananara Nord and Rigny. Eastern mangroves regenerate quite well, with a regeneration rate of over 500%. Their height and basal area range respectively between 1.7 - 12 m and 7 - 42 m2·ha-1. The aboveground biomass perfacies can go up to 47 t·ha-1, or even more, at the level of the large homogeneous mangrove of Mananara and Rigny (>70 t·ha-1), whereas this one does not exceed 10 - 20 t·ha-1 in the sporadic mangroves of Foulpointe and Manompana. The carbon sequestration capacity of the aboveground biomass is estimated at more than 5 - 20 t·ha-1, along a South-North gradient, equivalent to a minimum sequestration potential of 21,300 to 85,200 t for the whole East. Despite these ecological potentials and the low annual clearance rates observed for some sites, this ecosystem is subject to anthropogenic pressures linked to urbanization, timber harvesting and irrational exploitation of fishery resources. 展开更多
关键词 malagasy EASTERN MANGROVE Pressures ECOLOGICAL POTENTIALS Carbon BIODIVERSITY
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