The M-shaped multi-row pile foundation retaining structure represents an enhanced version of conventional multi-row anti-sliding support systems.To date,the implementation of M-shaped pile configurations in foundation...The M-shaped multi-row pile foundation retaining structure represents an enhanced version of conventional multi-row anti-sliding support systems.To date,the implementation of M-shaped pile configurations in foundation pit excavations has not been extensively investigated,with particularly scant research focusing on their load-bearing mechanisms and stress redistribution characteristics.Furthermore,numerical modeling methodologies for such geometrically optimized pile networks remain underdeveloped compared to practical engineering applications,creating a notable research-practice gap in geotechnical engineering.A comparative finite element analysis was systematically conducted using ABAQUS software to establish three distinct excavation support configurations:single-row cantilever retaining structures,three-row cantilever configurations,and M-shaped multi-row pile foundation systems.Subsequent numerical simulations enabled quantitative comparisons of critical performance indicators,including pile stress distribution patterns,lateral displacement profiles,and bending moment diagrams across different structural typologies.The parametric investigation revealed characteristic mechanical responses associated with each configuration,establishing corresponding mechanical principles governing the interaction between pile topology and soil-structure behavior towers.The findings of this study provide critical references for the design optimization of M-shaped multi-row pile foundation retaining systems.展开更多
Dear Editor,Iam Dr.Ping-Hong Lai,from the Jiangxi Eye Center,Jiangxi Provincial People＇s Hospital,Nanchang,Jiangxi Province,China.I would like to present the technique of subconjunctival M-shaped limbus incision for ...Dear Editor,Iam Dr.Ping-Hong Lai,from the Jiangxi Eye Center,Jiangxi Provincial People＇s Hospital,Nanchang,Jiangxi Province,China.I would like to present the technique of subconjunctival M-shaped limbus incision for a series of cases with hard cataracts.展开更多
Herein,an intense electrochemiluminescence(ECL)was achieved based on Pt hollow nanospheres/rubrene nanoleaves(Pt HNSs/Rub NLs)without the addition of any coreactant,which was employed for ultrasensitive detection of c...Herein,an intense electrochemiluminescence(ECL)was achieved based on Pt hollow nanospheres/rubrene nanoleaves(Pt HNSs/Rub NLs)without the addition of any coreactant,which was employed for ultrasensitive detection of carcinoembryonic antigen(CEA)coupled with an M-shaped DNA walker(M-DNA walker)as signal switch.Specifically,in comparison with platinum nanoparticles(Pt NPs),Pt HNSs revealed excellent catalytic performance and pore confinement-enhanced ECL,which could significantly amplify ECL intensity of Rub NLs/dissolved O_(2)(DO)binary system.Then,the tracks and M-DNA walker were confined on the Pt HNSs simultaneously to promote the reaction efficiency,whose M-structure boosted the interaction sites between walking strands and tracks and reduced the rigidity of their recognition.Once the CEA approached the sensing interface,the M-DNA walker was activated based on highly specific aptamer recognition to recover ECL intensity with the assistance of exonucleaseⅢ(ExoⅢ).As proof of concept,the“on-off-on”switch aptasensor was constructed for CEA detection with a low detection limit of 0.20 fg/m L.The principle of the constructed ECL aptasensor also enables a universal platform for sensitive detection of other tumor markers.展开更多
Background Nasal alarplasty is an important component of esthetic rhinoplasty in Asians.The two main surgical techniques that correct alar hypertrophy by reducing the height or length often leave external scars and ar...Background Nasal alarplasty is an important component of esthetic rhinoplasty in Asians.The two main surgical techniques that correct alar hypertrophy by reducing the height or length often leave external scars and are associated with a high relapse rate.Methods We developed a new technique,called three-dimensional(3D)M-shaped resection,which corrects both the nasal alar height and length and simultaneously minimizes external scarring.We performed this procedure from January 2013 to September 2016 in 49 consecutive female patients diagnosed with saddle nose and nasal alar hypertrophy.Their mean age was 28.6(range,18–40)years.All patients had previously undergone simple rhinoplasty.Nasal alar length and height,nostril length and width,and maximal nose width were analyzed preoperatively and postoperatively from photographs.Results After a mean of 9(range,3–24)months of follow-up,surgery was considered successful in 46 women(94%)with good cosmetic effects.In three patients,nasal alar hypertrophy recurred(6 months postoperatively).There were no early complications such as hematomas,infections,skin or mucosal necrosis,or wound dehiscence.The mean reductions postoperatively were 1.7 mm and 0.9 mm for nasal alar length and height,respectively,1.6 mm for both nostril length and width,and 3.5 mm for nose width.Conclusion The 3D M-shaped resection for nasal alar hypertrophy effectively reduced hypertrophy in 94%of patients for up to 24 months,producing minimal external scars and good cosmetic effects.It is a simple and convenient technique that is an effective and safe option for nasal alarplasty.展开更多
In this work two different fluorochromes （Alexa 594 and Alexa 680） are conjugated to the same monoclonal antibody （Cetuximab） for obtaining a characteristic M-shaped dual-peak spectrum. Dual-labeling of Cetuximab ...In this work two different fluorochromes （Alexa 594 and Alexa 680） are conjugated to the same monoclonal antibody （Cetuximab） for obtaining a characteristic M-shaped dual-peak spectrum. Dual-labeling of Cetuximab by mixing both fluorochromes before the conjugation step gives spectral results similar to those of mixing of fluorochrome-labeled Cetuximab after the conjugation step （P 〉 0.05）. In conclusion, both methods may be used equivalently for producing a dual-labeled single-antibody probe. Future studies may test whether the M-shaped spectrum may increase the diagnostic confidence in tumor-targeted multispectral optical imaging.展开更多
In the realm of low-level vision tasks,such as image deraining and dehazing,restoring images distorted by adverse weather conditions remains a significant challenge.The emergence of abundant computational resources ha...In the realm of low-level vision tasks,such as image deraining and dehazing,restoring images distorted by adverse weather conditions remains a significant challenge.The emergence of abundant computational resources has driven the dominance of deep Convolutional Neural Networks(CNNs),supplanting traditional methods reliant on prior knowledge.However,the evolution of CNN architectures has tended towards increasing complexity,utilizing intricate structures to enhance performance,often at the expense of computational efficiency.In response,we propose the Selective Kernel Dense Residual M-shaped Network(SKDRMNet),a flexible solution adept at balancing computational efficiency with network accuracy.A key innovation is the incorporation of an M-shaped hierarchical structure,derived from the U-Net framework as M-Network(M-Net),within which the Selective Kernel Dense Residual Module(SDRM)is introduced to reinforce multi-scale semantic feature maps.Our methodology employs two sampling techniques-bilinear and pixel unshuffled and utilizes a multi-scale feature fusion approach to distil more robust spatial feature map information.During the reconstruction phase,feature maps of varying resolutions are seamlessly integrated,and the extracted features are effectively merged using the Selective Kernel Fusion Module(SKFM).Empirical results demonstrate the comprehensive superiority of SKDRMNet across both synthetic and real rain and haze datasets.展开更多
Piled embankments,which offer many advantages,are increasingly popular in construction of high-speed railways in China.Although the performance of piled embankment under static loading is well-known,the behavior under...Piled embankments,which offer many advantages,are increasingly popular in construction of high-speed railways in China.Although the performance of piled embankment under static loading is well-known,the behavior under the dynamic train load of a high-speed railway is not yet understood.In light of this,a heavily instrumented piled embankment model was set up,and a model test was carried out,in which a servo-hydraulic actuator outputting M-shaped waves was adopted to simulate the process of a running train.Earth pressure,settlement,strain in the geogrid and pile and excess pore water pressure were measured.The results show that the soil arching height under the dynamic train load of a high-speed railway is shorter than under static loading.The growth trend for accumulated settlement slowed down after long-term vibration although there was still a tendency for it to increase.Accumulated geogrid strain has an increasing tendency after long-term vibration.The closer the embankment edge,the greater the geogrid strain over the subsoil.Strains in the pile were smaller under dynamic train loads,and their distribution was different from that under static loading.At the same elevation,excess pore water pressure under the track slab was greater than that under the embankment shoulder.展开更多
In this article, the authors study the exact traveling wave solutions of modified Zakharov equations for plasmas with a quantum correction by hyperbolic tangent function expansion method, hyperbolic secant expansion m...In this article, the authors study the exact traveling wave solutions of modified Zakharov equations for plasmas with a quantum correction by hyperbolic tangent function expansion method, hyperbolic secant expansion method, and Jacobi elliptic function ex- pansion method. They obtain more exact traveling wave solutions including trigonometric function solutions, rational function solutions, and more generally solitary waves, which are called classical bright soliton, W-shaped soliton, and M-shaped soliton.展开更多
The controllable periodic M-shape gratings are fabricated on the surface of silica glass by three coplanar interfering beams from a single femtosecond pulse. The configuration of the M-shape periodic structure is char...The controllable periodic M-shape gratings are fabricated on the surface of silica glass by three coplanar interfering beams from a single femtosecond pulse. The configuration of the M-shape periodic structure is characterized by optical microscopy and atomic force microscopy. The experimental results and the theoretical simulation show that the period and the modulation depth ratio between the neighboring grooves of the fabricated gratings can be controlled by adjusting the collision angles and pulse energy of the three beams, respectively.展开更多
文摘The M-shaped multi-row pile foundation retaining structure represents an enhanced version of conventional multi-row anti-sliding support systems.To date,the implementation of M-shaped pile configurations in foundation pit excavations has not been extensively investigated,with particularly scant research focusing on their load-bearing mechanisms and stress redistribution characteristics.Furthermore,numerical modeling methodologies for such geometrically optimized pile networks remain underdeveloped compared to practical engineering applications,creating a notable research-practice gap in geotechnical engineering.A comparative finite element analysis was systematically conducted using ABAQUS software to establish three distinct excavation support configurations:single-row cantilever retaining structures,three-row cantilever configurations,and M-shaped multi-row pile foundation systems.Subsequent numerical simulations enabled quantitative comparisons of critical performance indicators,including pile stress distribution patterns,lateral displacement profiles,and bending moment diagrams across different structural typologies.The parametric investigation revealed characteristic mechanical responses associated with each configuration,establishing corresponding mechanical principles governing the interaction between pile topology and soil-structure behavior towers.The findings of this study provide critical references for the design optimization of M-shaped multi-row pile foundation retaining systems.
文摘Dear Editor,Iam Dr.Ping-Hong Lai,from the Jiangxi Eye Center,Jiangxi Provincial People＇s Hospital,Nanchang,Jiangxi Province,China.I would like to present the technique of subconjunctival M-shaped limbus incision for a series of cases with hard cataracts.
基金financially supported by the National Natural Science Foundation(NNSF)of China(No.22022408)the Chongqing Talents Personnel Support Program(No.NCQYC201905067)the Fundamental Research Funds for the Central Universities(No.XDJK2019TJ002)。
文摘Herein,an intense electrochemiluminescence(ECL)was achieved based on Pt hollow nanospheres/rubrene nanoleaves(Pt HNSs/Rub NLs)without the addition of any coreactant,which was employed for ultrasensitive detection of carcinoembryonic antigen(CEA)coupled with an M-shaped DNA walker(M-DNA walker)as signal switch.Specifically,in comparison with platinum nanoparticles(Pt NPs),Pt HNSs revealed excellent catalytic performance and pore confinement-enhanced ECL,which could significantly amplify ECL intensity of Rub NLs/dissolved O_(2)(DO)binary system.Then,the tracks and M-DNA walker were confined on the Pt HNSs simultaneously to promote the reaction efficiency,whose M-structure boosted the interaction sites between walking strands and tracks and reduced the rigidity of their recognition.Once the CEA approached the sensing interface,the M-DNA walker was activated based on highly specific aptamer recognition to recover ECL intensity with the assistance of exonucleaseⅢ(ExoⅢ).As proof of concept,the“on-off-on”switch aptasensor was constructed for CEA detection with a low detection limit of 0.20 fg/m L.The principle of the constructed ECL aptasensor also enables a universal platform for sensitive detection of other tumor markers.
文摘Background Nasal alarplasty is an important component of esthetic rhinoplasty in Asians.The two main surgical techniques that correct alar hypertrophy by reducing the height or length often leave external scars and are associated with a high relapse rate.Methods We developed a new technique,called three-dimensional(3D)M-shaped resection,which corrects both the nasal alar height and length and simultaneously minimizes external scarring.We performed this procedure from January 2013 to September 2016 in 49 consecutive female patients diagnosed with saddle nose and nasal alar hypertrophy.Their mean age was 28.6(range,18–40)years.All patients had previously undergone simple rhinoplasty.Nasal alar length and height,nostril length and width,and maximal nose width were analyzed preoperatively and postoperatively from photographs.Results After a mean of 9(range,3–24)months of follow-up,surgery was considered successful in 46 women(94%)with good cosmetic effects.In three patients,nasal alar hypertrophy recurred(6 months postoperatively).There were no early complications such as hematomas,infections,skin or mucosal necrosis,or wound dehiscence.The mean reductions postoperatively were 1.7 mm and 0.9 mm for nasal alar length and height,respectively,1.6 mm for both nostril length and width,and 3.5 mm for nose width.Conclusion The 3D M-shaped resection for nasal alar hypertrophy effectively reduced hypertrophy in 94%of patients for up to 24 months,producing minimal external scars and good cosmetic effects.It is a simple and convenient technique that is an effective and safe option for nasal alarplasty.
文摘In this work two different fluorochromes （Alexa 594 and Alexa 680） are conjugated to the same monoclonal antibody （Cetuximab） for obtaining a characteristic M-shaped dual-peak spectrum. Dual-labeling of Cetuximab by mixing both fluorochromes before the conjugation step gives spectral results similar to those of mixing of fluorochrome-labeled Cetuximab after the conjugation step （P 〉 0.05）. In conclusion, both methods may be used equivalently for producing a dual-labeled single-antibody probe. Future studies may test whether the M-shaped spectrum may increase the diagnostic confidence in tumor-targeted multispectral optical imaging.
文摘In the realm of low-level vision tasks,such as image deraining and dehazing,restoring images distorted by adverse weather conditions remains a significant challenge.The emergence of abundant computational resources has driven the dominance of deep Convolutional Neural Networks(CNNs),supplanting traditional methods reliant on prior knowledge.However,the evolution of CNN architectures has tended towards increasing complexity,utilizing intricate structures to enhance performance,often at the expense of computational efficiency.In response,we propose the Selective Kernel Dense Residual M-shaped Network(SKDRMNet),a flexible solution adept at balancing computational efficiency with network accuracy.A key innovation is the incorporation of an M-shaped hierarchical structure,derived from the U-Net framework as M-Network(M-Net),within which the Selective Kernel Dense Residual Module(SDRM)is introduced to reinforce multi-scale semantic feature maps.Our methodology employs two sampling techniques-bilinear and pixel unshuffled and utilizes a multi-scale feature fusion approach to distil more robust spatial feature map information.During the reconstruction phase,feature maps of varying resolutions are seamlessly integrated,and the extracted features are effectively merged using the Selective Kernel Fusion Module(SKFM).Empirical results demonstrate the comprehensive superiority of SKDRMNet across both synthetic and real rain and haze datasets.
基金National Natural Science Foundation of China under Grant Nos.51622803,51378177 and 51420105013the 111 Project under Grant No.B13024
文摘Piled embankments,which offer many advantages,are increasingly popular in construction of high-speed railways in China.Although the performance of piled embankment under static loading is well-known,the behavior under the dynamic train load of a high-speed railway is not yet understood.In light of this,a heavily instrumented piled embankment model was set up,and a model test was carried out,in which a servo-hydraulic actuator outputting M-shaped waves was adopted to simulate the process of a running train.Earth pressure,settlement,strain in the geogrid and pile and excess pore water pressure were measured.The results show that the soil arching height under the dynamic train load of a high-speed railway is shorter than under static loading.The growth trend for accumulated settlement slowed down after long-term vibration although there was still a tendency for it to increase.Accumulated geogrid strain has an increasing tendency after long-term vibration.The closer the embankment edge,the greater the geogrid strain over the subsoil.Strains in the pile were smaller under dynamic train loads,and their distribution was different from that under static loading.At the same elevation,excess pore water pressure under the track slab was greater than that under the embankment shoulder.
基金Supported by the National Natural Science Foundation of China (10871075)Natural Science Foundation of Guangdong Province,China (9151064201000040)
文摘In this article, the authors study the exact traveling wave solutions of modified Zakharov equations for plasmas with a quantum correction by hyperbolic tangent function expansion method, hyperbolic secant expansion method, and Jacobi elliptic function ex- pansion method. They obtain more exact traveling wave solutions including trigonometric function solutions, rational function solutions, and more generally solitary waves, which are called classical bright soliton, W-shaped soliton, and M-shaped soliton.
基金Project supported by the Science and Technology Key Program of Shandong Province,China (Grant No 2008GG10004020)the Program of Excellent Team in the Harbin Institute of Technology,China
文摘The controllable periodic M-shape gratings are fabricated on the surface of silica glass by three coplanar interfering beams from a single femtosecond pulse. The configuration of the M-shape periodic structure is characterized by optical microscopy and atomic force microscopy. The experimental results and the theoretical simulation show that the period and the modulation depth ratio between the neighboring grooves of the fabricated gratings can be controlled by adjusting the collision angles and pulse energy of the three beams, respectively.
