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Energy retrofit and conservation of a historic building using multi-objective optimization and an analytic hierarchy process 被引量:4
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作者 Francesca Roberti Ulrich Filippi Oberegger +2 位作者 Elena Lucchi Alexandra Troi 侯恩哲 《建筑节能》 CAS 2017年第3期9-9,共1页
When deciding on the best historic building retrofit,energy savings and thermal comfort can be quantitatively evaluated using an energy model,whereas conservation compatibility is intrinsically qualitative and reflect... When deciding on the best historic building retrofit,energy savings and thermal comfort can be quantitatively evaluated using an energy model,whereas conservation compatibility is intrinsically qualitative and reflects the perspective of the local heritage authority. We present a methodology that permits finding and comparing optimal retrofits for historic buildings in a multi-perspective and quantitative way. We use an analytic hierarchyprocess to quantify conservation compatibility by distilling a conservation score from the opinions of 10 experts in the field. This score,along with energy needs for heating and cooling and thermal comfort,are the three targets of a multi-objective optimization aimed at identifying optimal retrofits for a medieval building in the north of Italy,destined to become a museum. Retrofit measures considered were different kinds of external and internal envelope insulation,improvement of airtightness,replacement of windows,and ventilative cooling. The result is a portfolio of optimal retrofits that cover the whole range of conservation compatibility. We showthat in the analyzed case heritage preservation is compatible with a four-fold reduction in energy needs at a high thermal comfort level. Even higher energy savings are only achievable at the cost of heritage degradation. 展开更多
关键词 《建筑节能》 英文摘要 编辑工作 期刊
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Book Review “William R. Spillers and Keith M. MacBain. Structural Optimization,Springer Dordrecht Heidelberg London New York,2009” 被引量:4
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作者 H. W. ZHANG and Z. KANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2010年第6期797-797,共1页
This book presents general theories and applications of structural optimization methods. The first chapter of the book introduces various basic concepts of structural optimization through several illustrative examples... This book presents general theories and applications of structural optimization methods. The first chapter of the book introduces various basic concepts of structural optimization through several illustrative examples. Chapter 2 is devoted to a comprehensive review of math- ematical programming methods, including classical methods such as the simplex method, the (SLP) method, the interior point method and relatively new approaches such as genetic algo- rithms. The third chapter presents the main topic of this book, the SLP methods based on the incremental equations of structures. Some useful techniques in implementation of SLP, including the move limit, scaling and active constraint identifying, are discussed. In chapter 4, classical optimality criterion approaches, including the fully stress approach for truss struc- tures and its extensions for membrane and plate structures, are presented with demonstrative examples. The remaining chapters develop an overview of structural optimization problems, among which are dynamic optimization, multi-criterion optimization, earlier work on the op- timal layouts of plates, as well as some practical issues in general size and shape optimization problems. 展开更多
关键词 Book Review macBain Spillers and Keith m Structural optimization Springer Dordrecht Heidelberg London New York 2009 William R
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Optimization of High Power 1.55-μm Single Lateral Mode Fabry-Perot Ridge Waveguide Lasers 被引量:1
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作者 柯青 谭少阳 +3 位作者 陆丹 张瑞康 王圩 吉晨 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第6期66-68,共3页
Optimization of the high power single-lateral-mode double-trench ridge waveguide semiconductor laser based on InGaAsP/InP quantum-well heterostructures with a separate confinement layer is reported. Two different wave... Optimization of the high power single-lateral-mode double-trench ridge waveguide semiconductor laser based on InGaAsP/InP quantum-well heterostructures with a separate confinement layer is reported. Two different waveguide structures of Fabry-Perot lasers emitting at a wavelength of 1.55 μm are fabricated. The influence of an effective lateral refractive index step on the maximum output power is investigated. A cw single mode output power of 165mW is obtained for a 1-mm-long uncoated laser. 展开更多
关键词 As Si INP optimization of High Power 1.55 m Single Lateral mode Fabry-Perot Ridge Waveguide Lasers
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Forecasting Multi-Step Ahead Monthly Reference Evapotranspiration Using Hybrid Extreme Gradient Boosting with Grey Wolf Optimization Algorithm 被引量:1
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作者 Xianghui Lu Junliang Fan +1 位作者 Lifeng Wu Jianhua Dong 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第11期699-723,共25页
It is important for regional water resources management to know the agricultural water consumption information several months in advance.Forecasting reference evapotranspiration(ET_(0))in the next few months is import... It is important for regional water resources management to know the agricultural water consumption information several months in advance.Forecasting reference evapotranspiration(ET_(0))in the next few months is important for irrigation and reservoir management.Studies on forecasting of multiple-month ahead ET_(0) using machine learning models have not been reported yet.Besides,machine learning models such as the XGBoost model has multiple parameters that need to be tuned,and traditional methods can get stuck in a regional optimal solution and fail to obtain a global optimal solution.This study investigated the performance of the hybrid extreme gradient boosting(XGBoost)model coupled with the Grey Wolf Optimizer(GWO)algorithm for forecasting multi-step ahead ET_(0)(1-3 months ahead),compared with three conventional machine learning models,i.e.,standalone XGBoost,multi-layer perceptron(MLP)and M5 model tree(M5)models in the subtropical zone of China.The results showed that theGWO-XGB model generally performed better than the other three machine learning models in forecasting 1-3 months ahead ET_(0),followed by the XGB,M5 and MLP models with very small differences among the three models.The GWO-XGB model performed best in autumn,while the MLP model performed slightly better than the other three models in summer.It is thus suggested to apply the MLP model for ET_(0) forecasting in summer but use the GWO-XGB model in other seasons. 展开更多
关键词 Reference evapotranspiration extreme gradient boosting Grey Wolf optimizer multi-layer perceptron m5 model tree
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Optimization of 1.3-μm InGaAsP/InP Electro-Absorption Modulator
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作者 王会涛 周代兵 +5 位作者 张瑞康 陆丹 赵玲娟 朱洪亮 王圩 吉晨 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第8期83-86,共4页
We report the simulation and experimental results of 1.3-μm InGaAsP/InP multiple quantum well (MQW) electro-absorption modulators (EAMs). In this work, the quantum confined Stark effect of the EAM is system- atic... We report the simulation and experimental results of 1.3-μm InGaAsP/InP multiple quantum well (MQW) electro-absorption modulators (EAMs). In this work, the quantum confined Stark effect of the EAM is system- atically analyzed through the finite element method. An optimized structure of the 1.3-μm InGaAsP/InP QW EAM is proposed for applications in 100 G ethernet. Then 1.3-μm InGaAsP/InP EAMs with f-3dB bandwidth of over 20 GHz and extinction ratio over 20 dB at 3 V bias voltage are demonstrated. 展开更多
关键词 EAm INP optimization of 1.3 m InGaAsP/InP Electro-Absorption modulator
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Combined model based on optimized multi-variable grey model and multiple linear regression 被引量:12
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作者 Pingping Xiong Yaoguo Dang +1 位作者 Xianghua wu Xuemei Li 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2011年第4期615-620,共6页
The construction method of background value is improved in the original multi-variable grey model (MGM(1,m)) from its source of construction errors. The MGM(1,m) with optimized background value is used to elimin... The construction method of background value is improved in the original multi-variable grey model (MGM(1,m)) from its source of construction errors. The MGM(1,m) with optimized background value is used to eliminate the random fluctuations or errors of the observational data of all variables, and the combined prediction model together with the multiple linear regression is established in order to improve the simulation and prediction accuracy of the combined model. Finally, a combined model of the MGM(1,2) with optimized background value and the binary linear regression is constructed by an example. The results show that the model has good effects for simulation and prediction. 展开更多
关键词 multi-variable grey model mGm(1 m)) backgroundvalue optimization multiple linear regression combined predic-tion model.
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Nonlinear optimal model and solving algorithms for platform planning problem in battlefield 被引量:2
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作者 WANG Xun YAO Peiyang +1 位作者 ZHANG Jieyong WAN Lujun 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2018年第5期983-994,共12页
Platform planning is one of the important problems in the command and control(C2) field. Hereto, we analyze the platform planning problem and present nonlinear optimal model aiming at maximizing the task completion qu... Platform planning is one of the important problems in the command and control(C2) field. Hereto, we analyze the platform planning problem and present nonlinear optimal model aiming at maximizing the task completion qualities. Firstly, we take into account the relation among tasks and build the single task nonlinear optimal model with a set of platform constraints. The Lagrange relaxation method and the pruning strategy are used to solve the model. Secondly, this paper presents optimization-based planning algorithms for efficiently allocating platforms to multiple tasks. To achieve the balance of the resource assignments among tasks, the m-best assignment algorithm and the pair-wise exchange(PWE)method are used to maximize multiple tasks completion qualities.Finally, a series of experiments are designed to verify the superiority and effectiveness of the proposed model and algorithms. 展开更多
关键词 platform planning nonlinear optimal model Lagrange relaxation method m-best algorithm pair-wise exchange(PWE)
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基于向量加权平均优化的盲源分离LTE-M同频干扰检测 被引量:2
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作者 王乃鑫 赵恒凯 +1 位作者 何庆军 郑国莘 《工业控制计算机》 2025年第2期45-47,共3页
轨道交通LTE-M(Long Term Evolution-Metro,基于轨道交通的长期演进)同频干扰检测关乎列控信号传输的可靠性,提出一种基于INFO(weIghted meaNoFvectOrs,基于向量加权平均)算法的盲源分离方法,即INFO-BSS。该方法以混合信号的最大化负熵... 轨道交通LTE-M(Long Term Evolution-Metro,基于轨道交通的长期演进)同频干扰检测关乎列控信号传输的可靠性,提出一种基于INFO(weIghted meaNoFvectOrs,基于向量加权平均)算法的盲源分离方法,即INFO-BSS。该方法以混合信号的最大化负熵为目标函数,用INFO优化算法替代牛顿迭代法,解决了牛顿迭代法初始参数易设置不当以及容易陷入局部最优的问题。仿真结果对比表明,在不同分辨率带宽、不同信干比等条件下,INFO-BSS的检测性能都要优于常规算法。 展开更多
关键词 同频干扰 LTE-m 盲源分离 向量加权平均优化算法
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A Novel Stochastic Framework for the Optimal Placement and Sizing of Distribution Static Compensator
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作者 Reza Khorram-Nia Aliasghar Baziar Abdollah Kavousi-Fard 《Journal of Intelligent Learning Systems and Applications》 2013年第2期90-98,共9页
This paper proposes a new stochastic framework based on the probabilistic load flow to consider the uncertainty effects in the Distribution Static Compensator (DSTATCOM) allocation and sizing problem. The proposed met... This paper proposes a new stochastic framework based on the probabilistic load flow to consider the uncertainty effects in the Distribution Static Compensator (DSTATCOM) allocation and sizing problem. The proposed method is based on the point estimate method (PEM) to capture the uncertainty associated with the forecast error of the loads. In order to explore the search space globally, a new optimization algorithm based on bat algorithm (BA) is proposed too. The objective functions to be investigated are minimization of the total active power losses and reducing the voltage deviation of the buses. Also to reach a proper balance between the optimization of both the objective functions, the idea of interactive fuzzy satisfying method is employed in the multi-objective formulation. The feasibility and satisfying performance of the proposed method is examined on the 69-bus IEEE distribution system. 展开更多
关键词 DSTATCOm ALLOCATION Uncertainty multi-objective optimization 2 m Point ESTImATE method
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Recent developments in optimal experimental designs for functional magnetic resonance imaging
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作者 Ming-Hung Kao M'hamed Temkit Weng Kee Wong 《World Journal of Radiology》 CAS 2014年第7期437-445,共9页
Functional magnetic resonance imaging(fMRI)is one of the leading brain mapping technologies for studying brain activity in response to mental stimuli.For neuroimaging studies utilizing this pioneering technology,there... Functional magnetic resonance imaging(fMRI)is one of the leading brain mapping technologies for studying brain activity in response to mental stimuli.For neuroimaging studies utilizing this pioneering technology,there is a great demand of high-quality experimental designs that help to collect informative data to make precise and valid inference about brain functions.This paper provides a survey on recent developments in experimental designs for fMRI studies.We briefly introduce some analytical and computational tools for obtaining good designs based on a specified design selection criterion.Research results about some commonly considered designs such as blocked designs,and m-sequences are also discussed.Moreover,we present a recently proposed new type of fMRI designs that can be constructed using a certain type of Hadamard matrices.Under certain assumptions,these designs can be shown to be statistically optimal.Some future research directions in design of fMRI experiments are also discussed. 展开更多
关键词 A-optimALITY Blocked designs Design EFFICIENCIES D-optimALITY Genetic algorithms HADAmARD sequences m-SEQUENCES
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大肠杆菌全细胞催化合成莱鲍迪苷M菌株的构建及发酵优化
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作者 王晓静 顾正华 +5 位作者 李默影 朱瑞 辛瑜 郭自涛 郭忠鹏 张梁 《食品与发酵工业》 北大核心 2025年第21期1-9,共9页
莱鲍迪苷M(rebaudioside M,Reb M)是一种天然的稀有甜味剂,以其安全性、高甜度和较少的回苦味而受到关注。从甜叶菊中提取莱鲍迪苷M的传统方法成本高且产量低。该研究采用大肠杆菌进行全细胞催化合成Reb M,避免了复杂的酶纯化步骤,并适... 莱鲍迪苷M(rebaudioside M,Reb M)是一种天然的稀有甜味剂,以其安全性、高甜度和较少的回苦味而受到关注。从甜叶菊中提取莱鲍迪苷M的传统方法成本高且产量低。该研究采用大肠杆菌进行全细胞催化合成Reb M,避免了复杂的酶纯化步骤,并适合工业化规模生产。该研究通过构建大肠杆菌底盘菌株并优化其发酵过程,实现了Reb M的高效合成。通过使用优化后的酶UGT76G1(突变T284S M88L L200A)和UGT91C1(突变F208M F379A),并引入蔗糖合酶atuSUS1以增强二磷酸尿苷-葡萄糖循环。同时,通过敲除araA(L-阿拉伯糖异构酶)和ushA(UDP糖水解酶)、过表达galU(葡萄糖-1-磷酸尿苷转移酶)并添加促溶标签XXA改造代谢途径,构建了出发菌株。通过发酵优化,确定最佳发酵条件为:在37℃下培养4 h后,加入0.1 mmol/L IPTG和15 g/L L-阿拉伯糖,在16℃下诱导16 h。在此条件下,出发菌株在42℃下反应24 h后,Reb M产量达到24.318 g/L,底物转化率达到91%,较初始条件提高了7.56倍。该研究成果为利用大肠杆菌生产莱鲍迪苷M提供了重要的指导。 展开更多
关键词 莱鲍迪苷m 重组大肠杆菌 全细胞催化 发酵优化
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在服务启动N-策略控制下具有检修策略和不同到达率的M/G/1排队分析
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作者 李丰芮 唐应辉 《运筹学学报(中英文)》 北大核心 2025年第2期113-127,共15页
本文以制造系统为背景,提出一个在服务启动N-策略控制下具有检修策略和不同到达率的M/G/1排队模型。首先运用更新过程理论、全概率分解技术和拉普拉斯变换,研究系统在任意时刻t队长的瞬态性质,得到了瞬态队长分布关于时间t的拉普拉斯变... 本文以制造系统为背景,提出一个在服务启动N-策略控制下具有检修策略和不同到达率的M/G/1排队模型。首先运用更新过程理论、全概率分解技术和拉普拉斯变换,研究系统在任意时刻t队长的瞬态性质,得到了瞬态队长分布关于时间t的拉普拉斯变换表达式。然后在瞬态分析的基础上,使用洛必达法则得到队长稳态分布的递推表达式。最后,在建立费用模型下,应用更新报酬定理,得到系统在长期运行下单位时间内的期望费用表达式,并通过数值实例讨论了系统启动服务的最优控制策略和最优检修策略。 展开更多
关键词 m/G/1排队 检修策略 服务启动N-策略 队长分布 最优策略
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4 K高效大冷量G-M制冷机二级回热器性能研究
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作者 周志坡 李奥 +4 位作者 何韩军 陶杰 屈方杰 段罗斌 董文庆 《低温工程》 北大核心 2025年第2期18-25,共8页
为了满足低温超导、核磁共振成像等领域对于液氦温区大冷量G-M制冷机的需求,对4 K双级GM制冷机进行了优化设计。通过数值模拟分析了不同回热器填充方式对4 K回热器损失以及性能的影响,并进行了实验验证。结果表明,二级回热器填充比例铅... 为了满足低温超导、核磁共振成像等领域对于液氦温区大冷量G-M制冷机的需求,对4 K双级GM制冷机进行了优化设计。通过数值模拟分析了不同回热器填充方式对4 K回热器损失以及性能的影响,并进行了实验验证。结果表明,二级回热器填充比例铅:钬铜:硫氧化钆为5∶2∶3时,制冷性能最优。从实际应用视角出发,考察了二级回热器不同热端温度下的损失及制冷量的变化情况,输入功6.5 kW,二级回热器热端温度60 K时,制冷量最大,达到2.37 W@4.2 K。同时对比了二级回热器填充钬铜颗粒和硫氧化钆颗粒制冷性能,当制冷温度为7 K及以下时,填充硫氧化钆的制冷量高于填充钬铜,且制冷温度越低,制冷量提升越明显。 展开更多
关键词 G-m 制冷机 液氦温区 大冷量 数值模拟 优化设计 实验验证
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在(p,N)-策略控制下耐烦服务员不中断多重休假M/G/1排队的最优控制策略
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作者 尹伶玉 唐应辉 旷欣宇 《控制与决策》 北大核心 2025年第7期2185-2193,共9页
研究在(p,N)-策略控制下耐烦服务员不中断多重休假M/G/1排队系统,其中每当系统变空时,服务员去进行一次不中断的休假,当服务员休假回来时,若系统中等待服务的顾客数大于等于事先设置的正整数阈值N(N≥1),则服务员立即开始服务直到系统... 研究在(p,N)-策略控制下耐烦服务员不中断多重休假M/G/1排队系统,其中每当系统变空时,服务员去进行一次不中断的休假,当服务员休假回来时,若系统中等待服务的顾客数大于等于事先设置的正整数阈值N(N≥1),则服务员立即开始服务直到系统再次空竭;若系统中有顾客但顾客数少于N个,则服务员以概率p(0≤p≤1)开始服务,以概率1-p不服务,处于通常的闲期,直到系统中的顾客数累积到N时才服务.通过系统稳态队长的随机分解定理得到系统稳态队长分布的概率母函数和平均队长表达式,同时应用Little公式得到任意顾客的平均等待时间表达式.然后建立系统的费用结构模型,利用更新报酬定理推得系统长期运行单位时间的期望成本费用函数.进一步,在没有平均等待时间和有平均等待时间约束下,通过数值实例分别讨论系统的优化控制问题,并确定使系统费用最小的一维最优控制策略N^(*)和当休假时间为T时的二维最优控制策略(N^(*),T^(*)). 展开更多
关键词 m/G/1排队 (p N)-策略 不中断多重休假 队长的随机分解 最优控制策略
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Pd-M双贵金属催化剂的加氢性能与结构优化研究
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作者 孟志宇 《山西化工》 2025年第12期179-181,共3页
为解决单金属Pd催化剂在选择性加氢中活性与选择性难以兼顾的问题,提出一种Pd-M双金属协同催化的结构优化方案。该方案以活性炭为载体,通过调控第二金属组分(M=Ru,Pt)制备系列催化剂,并以苯乙炔加氢为模型反应系统评价其性能。研究结果... 为解决单金属Pd催化剂在选择性加氢中活性与选择性难以兼顾的问题,提出一种Pd-M双金属协同催化的结构优化方案。该方案以活性炭为载体,通过调控第二金属组分(M=Ru,Pt)制备系列催化剂,并以苯乙炔加氢为模型反应系统评价其性能。研究结果表明,与单金属Pd相比,Pd-Pt催化剂的选择性由92.3%提升至96.5%且稳定性优异,成功揭示了双金属协同效应对催化性能的定向调控规律。 展开更多
关键词 Pd-m双金属 贵金属催化剂 加氢性能 结构优化 构效关系
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MGM(1,m)模型背景值的优化 被引量:38
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作者 熊萍萍 党耀国 王正新 《控制与决策》 EI CSCD 北大核心 2011年第6期806-810,815,共6页
基于MGM(1,m)模型时间响应式的形式和累加生成序列的准指数规律,研究了该模型的背景值优化问题.在分析传统MGM(1,m)模型背景值误差的基础上,利用非齐次指数函数逼近模型中各变量的一阶累加生成序列,经过一系列数学公式的推导,得到了MGM(... 基于MGM(1,m)模型时间响应式的形式和累加生成序列的准指数规律,研究了该模型的背景值优化问题.在分析传统MGM(1,m)模型背景值误差的基础上,利用非齐次指数函数逼近模型中各变量的一阶累加生成序列,经过一系列数学公式的推导,得到了MGM(1,m)模型背景值的优化公式.通过实例表明了该式的优化效果,同时表明了采用背景值优化的方法可以显著提高传统MGM(1,m)模型的模拟精度和预测精度. 展开更多
关键词 灰色系统 mGm(1 m)模型 背景值 优化
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基于L-M优化算法的BP神经网络的作物需水量预测模型 被引量:50
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作者 张兵 袁寿其 +2 位作者 成立 袁建平 从小青 《农业工程学报》 EI CAS CSCD 北大核心 2004年第6期73-76,共4页
应用L-M优化算法BP神经网络,通过多维气象数据(太阳辐射、空气温度、湿度)与作物需水量的相关分析,来确定网络的拓扑结构,建立作物需水量的人工神经网络模型。用美国田纳西州大学高原实验室所测的100d气象数据为输入、作物需水量为输出... 应用L-M优化算法BP神经网络,通过多维气象数据(太阳辐射、空气温度、湿度)与作物需水量的相关分析,来确定网络的拓扑结构,建立作物需水量的人工神经网络模型。用美国田纳西州大学高原实验室所测的100d气象数据为输入、作物需水量为输出来训练建立好的BP神经网络,仿真表明该神经网络能很好地解决需水量多影响因素之间的不确定性和非线性,模型的预测精度较高,同时通过一组非样本天气环境参数和作物需水量来验证该神经网络,也得到了较好的预测结果,能够满足灌溉的精度要求。 展开更多
关键词 BP神经网络 作物需水量 L—m优化算法 预测模型
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基于L-M优化算法的水稻螟虫预测模型及其初步应用 被引量:15
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作者 高艳萍 于红 +2 位作者 崔新忠 姜国兴 王美妮 《农业工程学报》 EI CAS CSCD 北大核心 2007年第7期162-165,共4页
农村稻区水稻螟虫发生量与多种气候因素相关,各因素之间存在相互作用,是非线性系统。神经网络能有效地描述非线性模型多输入和不确定的特性。传统的BP网络在训练时易陷入局部极小点从而导致训练时间长、收敛速度慢,采用Levenberg-Marqua... 农村稻区水稻螟虫发生量与多种气候因素相关,各因素之间存在相互作用,是非线性系统。神经网络能有效地描述非线性模型多输入和不确定的特性。传统的BP网络在训练时易陷入局部极小点从而导致训练时间长、收敛速度慢,采用Levenberg-Marquardt优化算法(简称L-M算法)能克服其缺点。在MATLAB中应用L-M算法对辽宁盘锦田间稻区进行水稻螟虫发生量的仿真预测,试验结果表明L-M优化算法的预测精度和收敛速度明显提高,为稻区防控虫害和精确喷药提供参考,具有实用价值。 展开更多
关键词 神经网络 L-m优化算法 预测模型 水稻螟虫
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基于Pro/M的大口径反射镜的变形分析及其支撑优化 被引量:6
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作者 陈晓娟 傅学农 +3 位作者 吴文凯 徐元利 王美聪 钟继根 《机械设计》 CSCD 北大核心 2008年第2期68-70,共3页
针对某大型激光装置中使用数量众多的大口径反射镜结构,运用Pro/E软件中的Mechanica研究其受重力影响的变形,并对反射镜的支撑结构参数进行灵敏度分析和优化计算,寻找使得反射镜片变形最小的结构参数,为大口径反射镜组件结构的设计提供... 针对某大型激光装置中使用数量众多的大口径反射镜结构,运用Pro/E软件中的Mechanica研究其受重力影响的变形,并对反射镜的支撑结构参数进行灵敏度分析和优化计算,寻找使得反射镜片变形最小的结构参数,为大口径反射镜组件结构的设计提供依据。 展开更多
关键词 Pro/m 大口径反射镜 重力变形 优化
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利用响应面分析法优化高山被孢霉ME-1生产花生四烯酸培养基成分研究(英文) 被引量:6
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作者 彭超 黄和 +3 位作者 金明杰 肖爱华 于文涛 刘欣 《食品科学》 EI CAS CSCD 北大核心 2009年第13期205-211,共7页
在利用高山被孢霉ME-1生产花生四烯酸(ARA)过程中,采用响应面分析法,对摇瓶中的培养基成分进行优化。建立了两个标准的多项式模型:在长达6.5d发酵过程中,当葡萄糖、酵母膏、KH2PO4和NaNO3浓度分别为90.16、12.50、3.80和3.54g/L时,生物... 在利用高山被孢霉ME-1生产花生四烯酸(ARA)过程中,采用响应面分析法,对摇瓶中的培养基成分进行优化。建立了两个标准的多项式模型:在长达6.5d发酵过程中,当葡萄糖、酵母膏、KH2PO4和NaNO3浓度分别为90.16、12.50、3.80和3.54g/L时,生物量将到最大,约36.86g/L;当葡萄糖、酵母膏、KH2PO4和NaNO3浓度分别为103.16、11.66、3.80和3.43g/L时,AA产量将到最大,约9.65g/L。预测值通过实验得到了充分的证实,预测值和实验结果相关性很好。发酵罐实验结果表明,在高山被孢霉ME-1大规模发酵生产过程中,对培养基进行优化,将同时引起生物量(发酵5d,约34.21±1.01g/L)和AA产量(发酵6d,约9.86±0.45g/L)的增加。 展开更多
关键词 花生四烯酸 高山被孢霉 优化 响应面法 发酵 油脂
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