BACKGROUND Peripheral artery disease(PAD)affects millions globally,with a 5.6%prevalence in 2015 impacting 236 million adults,rising above 10%in those over 60 due to factors like diabetes and smoking.Post-revasculariz...BACKGROUND Peripheral artery disease(PAD)affects millions globally,with a 5.6%prevalence in 2015 impacting 236 million adults,rising above 10%in those over 60 due to factors like diabetes and smoking.Post-revascularization,single antiplatelet therapy(SAPT)is standard,but dual antiplatelet therapy(DAPT)may improve outcomes,though duration and bleeding risks are unclear.The 2024 American College of Cardiology/American Heart Association guidelines endorse short-term DAPT,yet evidence gaps remain in comparative efficacy and safety.We hypothesized that DAPT reduces cardiovascular events and reinterventions vs SAPT without significantly elevating bleeding in PAD patients’post-lower extremity revascularization.AIM To evaluate the efficacy and safety of DAPT vs SAPT in PAD patients’post-revascularization.METHODS This systematic review and meta-analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,searching PubMed,EMBASE,and ScienceDirect up to July 2025.Included were randomized controlled trials(RCTs)and cohort studies from various global settings(e.g.,hospitals,tertiary care)comparing DAPT(aspirin plus P2Y12 inhibitor for>1 month)to SAPT in symptomatic PAD patients undergoing endovascular or surgical revascularization(n up to 28244 participants selected via eligibility criteria).Data were pooled using random-effects models for risk ratio(RR)with 95%CI;heterogeneity was assessed via the I²statistic.Quality appraisal used Risk of Bias in Non-randomized Studies of Interventions for cohorts and Risk of Bias 2.0 for RCTs;certainty was evaluated via Grading of Recommendations Assessment,Development and Evaluation(GRADE).RESULTS Twelve studies(3 RCTs,9 cohorts,conducted 2010–2025 with follow-ups of 6 months to 5 years)were included.DAPT showed no significant difference but a trend toward reduced all-cause mortality(RR:0.52,95%CI:0.27–1.01,P=0.05,DAPT of 298/9545 events vs SAPT of 165/566 events)or stroke(RR:0.72,95%CI:0.30–1.72,P=0.46,DAPT of 16/3729 events vs SAPT of 41/7673 events)vs SAPT.DAPT significantly reduced cardiac mortality(RR:0.46,95%CI:0.27–0.80,P=0.006,DAPT of 78/2903 events vs SAPT of 171/1465 events,risk difference:-5.4%),myocardial infarction(RR:0.82,95%CI:0.71–0.94,P=0.004,DAPT of 233/7704 events vs SAPT of 262/9130 events,risk difference:-1.8%),and major reintervention(RR:0.58,95%CI:0.35–0.98,P=0.04,DAPT of 803/205 events vs SAPT of 1197/4 events,risk difference:-42%).Bleeding showed no difference(RR:1.12,95%CI:0.42–3.03,P=0.82,DAPT of 195/2775 events vs SAPT of 202/8234 events).Heterogeneity was high(I^(2)=59%–97%).Quality revealed moderate to serious bias in cohorts and some concerns in RCTs;GRADE certainty moderate for cardiac mortality,myocardial infarction,reintervention,low for others due to inconsistency and imprecision.CONCLUSION DAPT reduces cardiac mortality,myocardial infarction,and major reintervention risks compared to SAPT in PAD post-revascularization without apparent bleeding increase,though limited by heterogeneity and low certainty for some outcomes.展开更多
This paper studies certain estimates for the lower bound of distance between unitary orbits of normal elements.We show that the distance between unitary orbits of normal elements of simple C^(*)-algebras of tracial ra...This paper studies certain estimates for the lower bound of distance between unitary orbits of normal elements.We show that the distance between unitary orbits of normal elements of simple C^(*)-algebras of tracial rank no more than k has a lower bound.Furthermore,if k≤1 and normal elements are commuting,then the lower bound will be better.Another result establishes a connection involving the spectrum distance operator Dc between a C^(*)-algebra of stable rank one C^(*)-algebra and its hereditary C^(*)-subalgebra.展开更多
The Cambrian and Lower Ordovician strata of the Bachu area in central Tarim Basin are characterized by extensively dolomitized,which have significant potential for favourable hydrocarbon reservoirs.The study herein co...The Cambrian and Lower Ordovician strata of the Bachu area in central Tarim Basin are characterized by extensively dolomitized,which have significant potential for favourable hydrocarbon reservoirs.The study herein combined petrographic,mineralogical and geochemical analyses to investigate the formation environments of these dolomite units and utilized Mg isotopic profiles to constrain the changes in the fluid flow trajectory.Positive excursions of δ^(18)O and upwardincreasing δ^(26)Mg profiles were observed in samples of the Wusonger formation(Є_(1)w),which may result from evaporation.Moreover,based on high ^(87)Sr/^(86)Sr ratios,high total REE concentrations and the occurrence of specific minerals,including quartz,barite,gypsum and pyrite,we interpret an evaporitic near-surface origin for the Є_(1)w dolomites.Samples of the Xiaoerblak Formation(Є_(1)x)are the product of seepage-reflux dolomitization,suggested by upward-decreasing δ^(26)Mg profiles and relatively lower ^(87)Sr/^(86)Sr ratios than the Є_(1)w samples.The overlapping isotope(δ^(18)O,δ^(13)C and ^(87)Sr/^(86)Sr)values between samples of the Shayilik(Є_(2)s)and Awatagh(Є_(2)a)Formation,in addition to the petrography evidence and Mg isotope variations,suggest that the formation of these dolomites were due to the shallow-burial dolomitization.The occurrence of the Xiaqiulitagh(Є_(3)ql)and Penglaiba(O_(1)p)dolomites along stylolites,together with their large crystals with opaque cores and clear rims and vertically constant δ^(26)Mg profiles,indicate that their formation may be related to pressure dissolution by mechanical compaction during deep-burial dolomitization.Therefore,the assembling of multiple petrographic,mineralogical and geochemical methods can shed light on the complicated generation processes of regional-scale dolomite within Tarim Basin or elsewhere.展开更多
BACKGROUND The therapeutic role of neurodynamic mobilization in improving lower limb function in patients with mild post-traumatic knee osteoarthritis remains poorly understood.AIM To further elucidate the role of neu...BACKGROUND The therapeutic role of neurodynamic mobilization in improving lower limb function in patients with mild post-traumatic knee osteoarthritis remains poorly understood.AIM To further elucidate the role of neurodynamic mobilization in facilitating knee joint functional recovery.METHODS Thirty-two patients with post-traumatic knee osteoarthritis treated at Chonghua Hospital of Traditional Chinese Medicine(Guilin)from March 2024 to August 2025 were randomly assigned to a control group(n=16)or an intervention group(n=16).Both groups received eight weeks of conventional treatment;and the intervention group additionally underwent neurodynamic mobilization.Outcomes including pain assessed by the visual analogue scale,active range of motion,Lysholm score,stork stand test,single hop test,and Y-balance test were assessed before and after the intervention.RESULTS There were no significant differences between the two groups in baseline characteristics,including gender,age,body mass index,or surgical side(P>0.05).Two-way repeated-measures analysis of variance demonstrated significant time×group interaction effects for the visual analogue scale score(F=13.364,P<0.05),Lysholm knee score(F=20.385,P<0.05),stork stand test(F=103.756,P<0.05),and Y-balance test score(F=8.089,P<0.05).CONCLUSION Neurodynamic mobilization effectively reduces pain,improves knee function,and enhances lower limb balance in patients with mild post-traumatic knee osteoarthritis.展开更多
Background:Prostate cancer is a common malignancy,with many men on active surveillance for localized,low-risk disease also experiencing lower urinary tract symptoms(LUTS)from benign prostatic hyperplasia(BPH).Water Va...Background:Prostate cancer is a common malignancy,with many men on active surveillance for localized,low-risk disease also experiencing lower urinary tract symptoms(LUTS)from benign prostatic hyperplasia(BPH).Water Vapor Thermal Therapy(WVTT)is a minimally invasive BPH treatment,but its safety and efficacy in this setting are unclear.Case Description:We report three men with localized PCa on active surveillance who underwent WVTT for LUTS.Conclusions:WVTT appears safe and potentially effective in treating LUTS,especially in those with lower-risk disease and smaller prostate volumes.Further research is needed to confirm safety,efficacy,and optimal patient selection.展开更多
The development of brain-computer interfaces(BCI)based on motor imagery(MI)has greatly improved patients’quality of life with movement disorders.The classification of upper limb MI has been widely studied and applied...The development of brain-computer interfaces(BCI)based on motor imagery(MI)has greatly improved patients’quality of life with movement disorders.The classification of upper limb MI has been widely studied and applied in many fields,including rehabilitation.However,the physiological representations of left and right lower limb movements are too close and activated deep in the cerebral cortex,making it difficult to distinguish their features.Therefore,classifying lower limbs motor imagery is more challenging.In this study,we propose a feature extraction method based on functional connectivity,which utilizes phase-locked values to construct a functional connectivity matrix as the features of the left and right legs,which can effectively avoid the problem of physiological representations of the left and right lower limbs being too close to each other during movement.In addition,considering the topology and the temporal characteristics of the electroencephalogram(EEG),we designed a temporal-spatial convolutional network(TSGCN)to capture the spatiotemporal information for classification.Experimental results show that the accuracy of the proposed method is higher than that of existing methods,achieving an average classification accuracy of 73.58%on the internal dataset.Finally,this study explains the network mechanism of left and right foot MI from the perspective of graph theoretic features and demonstrates the feasibility of decoding lower limb MI.展开更多
The India-Asia collision resulted in the formation of Qinghai-Tibet Plateau.Lower crustal flow model was proposed to explain the mechanism of Cenozoic tectonic deformation of Qinghai-Tibet Plateau.In this study,we pro...The India-Asia collision resulted in the formation of Qinghai-Tibet Plateau.Lower crustal flow model was proposed to explain the mechanism of Cenozoic tectonic deformation of Qinghai-Tibet Plateau.In this study,we propose a new approach by combining centrifugal analog modeling with numerical simulation to simulate the tectonic uplift history of the plateau based on the lower crustal flow model,and to investigate the material migration characteristics and the influence of crustal motion velocity and ductile layer viscosity on the plateau tectonic geomorphology.The models reproduce steep-sided flat-topped geomorphic features and clockwise rotation of the material at eastern Himalayan Syntaxis,verifying the rationality of the models.The results show that the greater the crustal motion velocity and the greater the ductile layer viscosity,the steeper the terrain change;and conversely,the smaller the crustal motion velocity and the smaller the ductile layer viscosity,the gentler the terrain change.This study further indicates that the weak lower crust plays an important role in the formation of geomorphic features and material migration characteristics of Qinghai-Tibet Plateau,and provides a new insight for the study of the uplift mechanism of the Tibetan Plateau.展开更多
This research presents a Human Lower Limb Activity Recognition(HLLAR)system that identifies specific activities and predicts the angles of the knees simultaneously,based on the EMG signals.The HLLAR systems streamline...This research presents a Human Lower Limb Activity Recognition(HLLAR)system that identifies specific activities and predicts the angles of the knees simultaneously,based on the EMG signals.The HLLAR systems streamlines the research on the lower limb activities.The HILLAR model includes Discrete Hermite Wavelets Transform-based Synchrosqueezing(DHWTS),Deep Two-Layer Multiscale Convolutional Neural Network(DTLMCNN),and Generalized Regression Neural Network(GRNN)as feature extraction,activity recognition,and knee angle prediction respectively.Electromyography signal-based automatic lower limb activity detection is crucial to rehabilitation and human movement analysis.Yet several of these methods face issues in feature extraction in complex data,overlapping signals,extraction of crucial parameters,and adaptation constraints.This research aims classify lower limb activities and predict knee joint angles from electromy-ography signals using HILLAR model.The model is validated on two datasets,comprising 26 subjects performing three classes of activities:walking,standing,and sitting.The proposed model obtained a classification accuracy of 99.95%,along with significant achievements in precision(99.93%),recall(99.91%),and F1-score(99.93%).The generalized regression neural network predicted angles of the knee joint with a root mean squared error of 1.25%.Robustness is demonstrated through consistent results in five-fold cross-validation and statistical significance testing(p-value=0.004,McNemar's test).Additionally,the proposed model showed superior performance over baseline methods by reducing error rates by 18%and decreasing processing time to 0.98 s.展开更多
Integration of renewable energy sources into power systems requires efficient multilevel inverters,capable of producing high-quality output voltage with low total harmonic distortion(THD).Conventional multilevel inver...Integration of renewable energy sources into power systems requires efficient multilevel inverters,capable of producing high-quality output voltage with low total harmonic distortion(THD).Conventional multilevel inverters often suffer from high component count,high switching stress,low voltage gain,and increased cost,limiting their practical application.This paper introduces a high-gain novel topology for multilevel inverters with reduced number of total components per level count,low voltage stress on power conductive devices,and minimizing a cost function,which depends on the number of components,standing voltage on switches and diodes,output voltage levels,and gain.The designed topology,which can be applied in photovoltaic(PV)systems,utilizes only one direct current(DC)input supply and a modular structure with the ability of capacitor’s voltage self-balancing.The high gain property and low THD of the proposed topology are two advantages that provide sine output waveform,with no need to a high DC input voltage source.Moreover,generalized topology,consisting of cascaded basic units,has been proposed.A comprehensive method has been proposed to determining the values of DC supplies in this configuration,aiming to minimize redundant switching modes and maximize the voltage levels count.The comparison with some other multilevel inverters confirms the desired performance of the basic version given inverter.A prototype has been also implemented and the experimental results have been obtained to verify the advantages of the proposed 25-level topology.展开更多
In this paper,a unified terminal sliding mode(UTSM)control method is proposed for second-order nonlinear systems with uncertainties and disturbances.It is seen that the newly defined terminal sliding surface is integr...In this paper,a unified terminal sliding mode(UTSM)control method is proposed for second-order nonlinear systems with uncertainties and disturbances.It is seen that the newly defined terminal sliding surface is integrated with both conventional and fast terminal sliding mode and exhibits design advantages such as a variable exponent,adjustable sliding mode parameters,and chattering-alleviation effect.The inherent dynamic properties of the closed-loop systems with the UTSM control are discussed in detail via the phase plane and Lyapunov stability theory.Both numerical simulations and experimental results show the flexible sliding manifold design,strong robustness against uncertain dynamics,and effective attenuation of chattering phenomenon.展开更多
Summary What''s New?:This study introduces a novel,periosteum-preserving iliac crest transverse transport(ICTT)technique for high-level lower extremity arteriosclerosis obliterans(LEASO),targeting patients uns...Summary What''s New?:This study introduces a novel,periosteum-preserving iliac crest transverse transport(ICTT)technique for high-level lower extremity arteriosclerosis obliterans(LEASO),targeting patients unsuitable for conventional revascularization.Technical Innovation:By relocating the osteotomy from the weight-bearing tibia to the non-weight-bearing ilium,this minimally invasive technique eliminates the risk of stress fractures,allows for immediate full weight-bearing,and expands indications to patients with proximal arterial occlusions.展开更多
Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial ...Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial magnetic stimulation(rTMS)on motor function in stroke patients.There have been relatively few studies on the effects of different modalities of rTMS on lower extremity motor function and corticospinal excitability in patients with stroke.The MEDLINE,Embase,Cochrane Library,ISI Science Citation Index,Physiotherapy Evidence Database,China National Knowledge Infrastructure Library,and ClinicalTrials.gov databases were searched.Parallel or crossover randomized controlled trials that addressed the effectiveness of rTMS in patients with stroke,published from inception to November 28,2019,were included.Standard pairwise meta-analysis was conducted using R version 3.6.1 with the“meta”package.Bayesian network analysis using the Markov chain Monte Carlo algorithm was conducted to investigate the effectiveness of different rTMS protocol interventions.Network meta-analysis results of 18 randomized controlled trials regarding lower extremity motor function recovery revealed that low-frequency rTMS had better efficacy in promoting lower extremity motor function recovery than sham stimulation.Network meta-analysis results of five randomized controlled trials demonstrated that highfrequency rTMS led to higher amplitudes of motor evoked potentials than low-frequency rTMS or sham stimulation.These findings suggest that rTMS can improve motor function in patients with stroke,and that low-frequency rTMS mainly affects motor function,whereas high-frequency rTMS increases the amplitudes of motor evoked potentials.More highquality randomized controlled trials are needed to validate this conclusion.The work was registered in PROSPERO(registration No.CRD42020147055)on April 28,2020.展开更多
A new species of tapejarid pterosaur, Huaxiapterus coroUatus sp. nov. is erected on the basis of a nearly complete skull and postcranial skeleton from the Lower Cretaceous Jiufotang Formation of Liaoning Province, Chi...A new species of tapejarid pterosaur, Huaxiapterus coroUatus sp. nov. is erected on the basis of a nearly complete skull and postcranial skeleton from the Lower Cretaceous Jiufotang Formation of Liaoning Province, China. Huaxiapterus coroUatus sp. nov. is characterized by a hatchet-shaped rectangular process on the premaxilla, whose short axis is perpendicular to the anterior margin of the premaxillae. Except for this process, other characters of the skull such as the breadth of the snout between the anterior margin of the nasoantorbital fenestra and the anterior margin of the premaxilla are similar to that of Huaxiapterus jii. Huaxiapterus and a second Chinese tapejarid, Sinopterus, share several unique cranial characters in common with Tapejara and these three genera appear to be more closely related to each other than to other azhdarchoids. The Chinese tapejarids （Sinopterus and Huaxiapterus） have relatively elongate skulls and weakly developed cranial crests and seem to be less derived than Tapejara, with its shorter, deeper skull and large cranial crest. Tupuxuarids （Tupuxuara and Thalassodromeus） have often been associated with tapejarids in the family Tapejaridae, but this relationship is controversial because some phylogenetic analyses have supported the pairing of tupuxuarids with Azhdarchidae. We propose that Tapejaridae be restricted to Tapejara, Sinopterus and Huaxiapterus.展开更多
BACKGROUNDDiabetes mellitus causes a large majority of non-traumatic major and minoramputations globally. Patients with diabetes are clinically complex with amultifactorial association between diabetic foot ulcers (DF...BACKGROUNDDiabetes mellitus causes a large majority of non-traumatic major and minoramputations globally. Patients with diabetes are clinically complex with amultifactorial association between diabetic foot ulcers (DFU) and subsequentlower extremity amputations (LEA). Few studies show the long-term outcomeswithin the cohort of DFU-associated LEA.AIMTo highlight the long-term outcomes of LEA as a result of DFU.METHODSPubMed/MEDLINE and Google Scholar were searched for key terms, “diabetes”,“foot ulcers”, “amputations” and “outcomes”. Outcomes such as mortality, reamputation,re-ulceration and functional impact were recorded. Peer-reviewedstudies with adult patients who had DFU, subsequent amputation and follow upof at least 1 year were included. Non-English language articles or studiesinvolving children were excluded.RESULTSA total of 22 publications with a total of 2334 patients were selected against theinclusion criteria for review. The weighted mean of re-amputation was 20.14%,29.63% and 45.72% at 1, 3 and 5 years respectively. The weighted mean of mortality at 1, 3 and 5 years were 13.62%, 30.25% and 50.55% respectively withsignificantly higher rates associated with major amputation, re-amputation andischemic cardiomyopathy.CONCLUSIONPrevious LEA, level of the LEA and patient comorbidities were significant riskfactors contributing to re-ulceration, re-amputation, mortality and depreciatedfunctional status.展开更多
In the South Yellow Sea Basin,Mesozoic–Paleozoic marine strata are generally well developed with large thickness,and no substantial breakthroughs have been made in hydrocarbon exploration.Through research,it is belie...In the South Yellow Sea Basin,Mesozoic–Paleozoic marine strata are generally well developed with large thickness,and no substantial breakthroughs have been made in hydrocarbon exploration.Through research,it is believed that the Upper Permian–Lower Triassic can be regarded as a long-term base-level cycle.Based on drilling data,characteristics of the lithology–electric property combination cyclicity,and the special lithology,the long-term base-level cycle was divided into five medium-term base-level cycles(MC1–MC5).On this basis,the Permian–Triassic sedimentary systems and their filling model were analyzed in accordance with the change of base-level cycle and transition of sedimentary environment,as well as characteristics of the drilling sedimentary facies and seismic facies.The results show that there were six sedimentary systems(fluvial,delta,tidal flat,open platform,restricted platform,and continental shelf)developed in the Upper Permian–Lower Triassic,the sedimentary systems were distributed such that the water was deep in the northwest and shallow in the southeast,and there were two base-level cycle filling models(a relatively stable tidal flat facies and a rapidly transgressive continental shelf facies to stable platform facies)developed in the Upper Permian–Lower Triassic.These models can provide a basis for evaluation of the Mesozoic–Paleozoic hydrocarbon geology in the South Yellow Sea Basin.展开更多
The study area is located in the south of Huanxian county,in Yan'an and Puxian counties and to the north of Xi'an.The Shanxi and lower Shihezi formations are important gas-bearing formations.Given our analysis...The study area is located in the south of Huanxian county,in Yan'an and Puxian counties and to the north of Xi'an.The Shanxi and lower Shihezi formations are important gas-bearing formations.Given our analysis of the direction of rivers,the contents of stable heavy minerals and of feldspar of palaeo river systems,the study area is divided into six palaeodrainage patterns corresponding to six feldspar regions and six sedimentary facies regions.On this basis,the distribution of sedimentary facies was also analyzed.During the Shanxi stage,a delta front was deposited in the Huanxian region and delta plains and fronts were deposited in the Pingliang,Chunhua-Yaoxian and Hancheng-Chengcheng regions.In the Yan'an-Daning region,only a delta front was developed.The distribution of sedimentary facies in the earlier Shihezi stage originated from the Shanxi stage.A delta front was developed in the Huanxian region while a delta plain and front developed in the Pingliang-Zhenyuan region during the same time.Lakes originated only in the Zhenyuan-Huanxian-Huachi-Zhengning and Daning-Jixian zones.This analytical method shows that different palaeodrainage patterns can be effectively distinguished in order to forecast sedimentary facies.展开更多
Lower extremity robotic exoskeletons(LEEX)can not only improve the ability of the human body but also provide healing treatment for people with lower extremity dysfunction.There are a wide range of application needs a...Lower extremity robotic exoskeletons(LEEX)can not only improve the ability of the human body but also provide healing treatment for people with lower extremity dysfunction.There are a wide range of application needs and development prospects in the military,industry,medical treatment,consumption and other felds,which has aroused widespread concern in society.This paper attempts to review LEEX technical development.First,the history of LEEX is briefy traced.Second,based on existing research,LEEX is classifed according to auxiliary body parts,structural forms,functions and felds,and typical LEEX prototypes and products are introduced.Then,the latest key technologies are analyzed and summarized,and the research contents,such as bionic structure and driving characteristics,human–robot interaction(HRI)and intentawareness,intelligent control strategy,and evaluation method of power-assisted walking efciency,are described in detail.Finally,existing LEEX problems and challenges are analyzed,a future development trend is proposed,and a multidisciplinary development direction of the key technology is provided.展开更多
The extended state observer(ESO)is the most important part of an emerging control technology known as active disturbance rejection control to this day,aiming at estimating"total disturbance"from observable m...The extended state observer(ESO)is the most important part of an emerging control technology known as active disturbance rejection control to this day,aiming at estimating"total disturbance"from observable measured output.In this paper,we construct a nonlinear ESO for a class of uncertain lower triangular nonlinear systems with stochastic disturbance and show its convergence,where the total disturbance includes internal uncertain nonlinear part and external stochastic disturbance.The numerical experiments are carried out to illustrate effectiveness of the proposed approach.展开更多
BACKGROUND Prostate artery embolization(PAE)is a promising minimally invasive therapy that improves lower urinary tract symptoms(LUTS)related to benign prostatic hyperplasia(BPH).Transurethral resection of the prostat...BACKGROUND Prostate artery embolization(PAE)is a promising minimally invasive therapy that improves lower urinary tract symptoms(LUTS)related to benign prostatic hyperplasia(BPH).Transurethral resection of the prostate(TURP)is the gold standard therapy for LUTS/BPH.AIM To evaluate the efficacy and safety of PAE vs TURP on LUTS related to BPH.METHODS A literature review was performed to identify all published articles on PAE vs TURP for LUTS/BPH.Sources included PubMed,Embase,Cochrane library databases,and Chinese databases before June 2022.A systematic review and meta-analysis were conducted.Outcome measurements were combined by calculating the mean difference with a 95%confidence interval.Statistical analysis was carried out using Review Manager 5.3.RESULTS Eleven studies involving 1070 participants were included.Compared with the TURP group,the PAE group had a similar effect on the International Index of Erectile Function(IPSS)score,Peak urinary flow rate(Qmax),postvoid residual volume(PVR),Prostate volume(PV),prostatic specific antigen(PSA),The International Index of Erectile Function short form(IIEF-5)scores,and erectile dysfunction during 24 mo follow-up.Lower quality of life(QoL)score,lower rate of retrograde ejaculation and shorter hospital stay in the PAE group.There was no participant death in either group.A higher proportion of haematuria,urinary incontinence and urinary stricture was identified in the TURP group.CONCLUSION PAE may be an appropriate option for elderly patients,patients who are not candidates for surgery,and patients who do not want to risk the potential adverse effects of TURP.Studies with large cases and long follow-up time are needed to validate results.展开更多
Li et al. in [3] obtained blow-up results for a system of Petrovskey equations in some different cases. In this article we obtain lower bounds for the blow up time under some considerations on initial data.
文摘BACKGROUND Peripheral artery disease(PAD)affects millions globally,with a 5.6%prevalence in 2015 impacting 236 million adults,rising above 10%in those over 60 due to factors like diabetes and smoking.Post-revascularization,single antiplatelet therapy(SAPT)is standard,but dual antiplatelet therapy(DAPT)may improve outcomes,though duration and bleeding risks are unclear.The 2024 American College of Cardiology/American Heart Association guidelines endorse short-term DAPT,yet evidence gaps remain in comparative efficacy and safety.We hypothesized that DAPT reduces cardiovascular events and reinterventions vs SAPT without significantly elevating bleeding in PAD patients’post-lower extremity revascularization.AIM To evaluate the efficacy and safety of DAPT vs SAPT in PAD patients’post-revascularization.METHODS This systematic review and meta-analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,searching PubMed,EMBASE,and ScienceDirect up to July 2025.Included were randomized controlled trials(RCTs)and cohort studies from various global settings(e.g.,hospitals,tertiary care)comparing DAPT(aspirin plus P2Y12 inhibitor for>1 month)to SAPT in symptomatic PAD patients undergoing endovascular or surgical revascularization(n up to 28244 participants selected via eligibility criteria).Data were pooled using random-effects models for risk ratio(RR)with 95%CI;heterogeneity was assessed via the I²statistic.Quality appraisal used Risk of Bias in Non-randomized Studies of Interventions for cohorts and Risk of Bias 2.0 for RCTs;certainty was evaluated via Grading of Recommendations Assessment,Development and Evaluation(GRADE).RESULTS Twelve studies(3 RCTs,9 cohorts,conducted 2010–2025 with follow-ups of 6 months to 5 years)were included.DAPT showed no significant difference but a trend toward reduced all-cause mortality(RR:0.52,95%CI:0.27–1.01,P=0.05,DAPT of 298/9545 events vs SAPT of 165/566 events)or stroke(RR:0.72,95%CI:0.30–1.72,P=0.46,DAPT of 16/3729 events vs SAPT of 41/7673 events)vs SAPT.DAPT significantly reduced cardiac mortality(RR:0.46,95%CI:0.27–0.80,P=0.006,DAPT of 78/2903 events vs SAPT of 171/1465 events,risk difference:-5.4%),myocardial infarction(RR:0.82,95%CI:0.71–0.94,P=0.004,DAPT of 233/7704 events vs SAPT of 262/9130 events,risk difference:-1.8%),and major reintervention(RR:0.58,95%CI:0.35–0.98,P=0.04,DAPT of 803/205 events vs SAPT of 1197/4 events,risk difference:-42%).Bleeding showed no difference(RR:1.12,95%CI:0.42–3.03,P=0.82,DAPT of 195/2775 events vs SAPT of 202/8234 events).Heterogeneity was high(I^(2)=59%–97%).Quality revealed moderate to serious bias in cohorts and some concerns in RCTs;GRADE certainty moderate for cardiac mortality,myocardial infarction,reintervention,low for others due to inconsistency and imprecision.CONCLUSION DAPT reduces cardiac mortality,myocardial infarction,and major reintervention risks compared to SAPT in PAD post-revascularization without apparent bleeding increase,though limited by heterogeneity and low certainty for some outcomes.
基金Supported by Zhejiang Provincial Natural Science Foundation of China(No.ZCLQN25A0103)。
文摘This paper studies certain estimates for the lower bound of distance between unitary orbits of normal elements.We show that the distance between unitary orbits of normal elements of simple C^(*)-algebras of tracial rank no more than k has a lower bound.Furthermore,if k≤1 and normal elements are commuting,then the lower bound will be better.Another result establishes a connection involving the spectrum distance operator Dc between a C^(*)-algebra of stable rank one C^(*)-algebra and its hereditary C^(*)-subalgebra.
基金supported by the Science&Technology Project of SINOPEC(No.P22125)the National Natural Science Foundation of China(No.41902162)。
文摘The Cambrian and Lower Ordovician strata of the Bachu area in central Tarim Basin are characterized by extensively dolomitized,which have significant potential for favourable hydrocarbon reservoirs.The study herein combined petrographic,mineralogical and geochemical analyses to investigate the formation environments of these dolomite units and utilized Mg isotopic profiles to constrain the changes in the fluid flow trajectory.Positive excursions of δ^(18)O and upwardincreasing δ^(26)Mg profiles were observed in samples of the Wusonger formation(Є_(1)w),which may result from evaporation.Moreover,based on high ^(87)Sr/^(86)Sr ratios,high total REE concentrations and the occurrence of specific minerals,including quartz,barite,gypsum and pyrite,we interpret an evaporitic near-surface origin for the Є_(1)w dolomites.Samples of the Xiaoerblak Formation(Є_(1)x)are the product of seepage-reflux dolomitization,suggested by upward-decreasing δ^(26)Mg profiles and relatively lower ^(87)Sr/^(86)Sr ratios than the Є_(1)w samples.The overlapping isotope(δ^(18)O,δ^(13)C and ^(87)Sr/^(86)Sr)values between samples of the Shayilik(Є_(2)s)and Awatagh(Є_(2)a)Formation,in addition to the petrography evidence and Mg isotope variations,suggest that the formation of these dolomites were due to the shallow-burial dolomitization.The occurrence of the Xiaqiulitagh(Є_(3)ql)and Penglaiba(O_(1)p)dolomites along stylolites,together with their large crystals with opaque cores and clear rims and vertically constant δ^(26)Mg profiles,indicate that their formation may be related to pressure dissolution by mechanical compaction during deep-burial dolomitization.Therefore,the assembling of multiple petrographic,mineralogical and geochemical methods can shed light on the complicated generation processes of regional-scale dolomite within Tarim Basin or elsewhere.
基金Supported by the Central Guided Local Science and Technology Development Fund Project for Science and Technology Innovation Base Construction,No.Guike ZY24212046National Natural Science Foundation of China,No.U22A2092+3 种基金Guangxi Education Science“the 14th Five-Year Plan”2024 Special Project“Research on Steam Education Practice in Rehabilitation Engineering”,No.2024ZJY304the Research Basic Ability Enhancement Program for Young and Middle-aged Teachers of Guangxi,No.2025KY2255the Innovation Project of GUET Graduate Education,No.2025YCXB010Natural Science Research Project of Guilin Life and Health Career Technical College,No.2025GKKY04.
文摘BACKGROUND The therapeutic role of neurodynamic mobilization in improving lower limb function in patients with mild post-traumatic knee osteoarthritis remains poorly understood.AIM To further elucidate the role of neurodynamic mobilization in facilitating knee joint functional recovery.METHODS Thirty-two patients with post-traumatic knee osteoarthritis treated at Chonghua Hospital of Traditional Chinese Medicine(Guilin)from March 2024 to August 2025 were randomly assigned to a control group(n=16)or an intervention group(n=16).Both groups received eight weeks of conventional treatment;and the intervention group additionally underwent neurodynamic mobilization.Outcomes including pain assessed by the visual analogue scale,active range of motion,Lysholm score,stork stand test,single hop test,and Y-balance test were assessed before and after the intervention.RESULTS There were no significant differences between the two groups in baseline characteristics,including gender,age,body mass index,or surgical side(P>0.05).Two-way repeated-measures analysis of variance demonstrated significant time×group interaction effects for the visual analogue scale score(F=13.364,P<0.05),Lysholm knee score(F=20.385,P<0.05),stork stand test(F=103.756,P<0.05),and Y-balance test score(F=8.089,P<0.05).CONCLUSION Neurodynamic mobilization effectively reduces pain,improves knee function,and enhances lower limb balance in patients with mild post-traumatic knee osteoarthritis.
文摘Background:Prostate cancer is a common malignancy,with many men on active surveillance for localized,low-risk disease also experiencing lower urinary tract symptoms(LUTS)from benign prostatic hyperplasia(BPH).Water Vapor Thermal Therapy(WVTT)is a minimally invasive BPH treatment,but its safety and efficacy in this setting are unclear.Case Description:We report three men with localized PCa on active surveillance who underwent WVTT for LUTS.Conclusions:WVTT appears safe and potentially effective in treating LUTS,especially in those with lower-risk disease and smaller prostate volumes.Further research is needed to confirm safety,efficacy,and optimal patient selection.
基金supported in part by the National Natural Science Foundation of China under Grant 62172368the Natural Science Foundation of Zhejiang Province under Grant LR22F020003.
文摘The development of brain-computer interfaces(BCI)based on motor imagery(MI)has greatly improved patients’quality of life with movement disorders.The classification of upper limb MI has been widely studied and applied in many fields,including rehabilitation.However,the physiological representations of left and right lower limb movements are too close and activated deep in the cerebral cortex,making it difficult to distinguish their features.Therefore,classifying lower limbs motor imagery is more challenging.In this study,we propose a feature extraction method based on functional connectivity,which utilizes phase-locked values to construct a functional connectivity matrix as the features of the left and right legs,which can effectively avoid the problem of physiological representations of the left and right lower limbs being too close to each other during movement.In addition,considering the topology and the temporal characteristics of the electroencephalogram(EEG),we designed a temporal-spatial convolutional network(TSGCN)to capture the spatiotemporal information for classification.Experimental results show that the accuracy of the proposed method is higher than that of existing methods,achieving an average classification accuracy of 73.58%on the internal dataset.Finally,this study explains the network mechanism of left and right foot MI from the perspective of graph theoretic features and demonstrates the feasibility of decoding lower limb MI.
基金supported by Excellent Research Group Project for Multiphase Evolution in Hyper-Gravity of the National Natural Science Foundation of China(No.52588202)。
文摘The India-Asia collision resulted in the formation of Qinghai-Tibet Plateau.Lower crustal flow model was proposed to explain the mechanism of Cenozoic tectonic deformation of Qinghai-Tibet Plateau.In this study,we propose a new approach by combining centrifugal analog modeling with numerical simulation to simulate the tectonic uplift history of the plateau based on the lower crustal flow model,and to investigate the material migration characteristics and the influence of crustal motion velocity and ductile layer viscosity on the plateau tectonic geomorphology.The models reproduce steep-sided flat-topped geomorphic features and clockwise rotation of the material at eastern Himalayan Syntaxis,verifying the rationality of the models.The results show that the greater the crustal motion velocity and the greater the ductile layer viscosity,the steeper the terrain change;and conversely,the smaller the crustal motion velocity and the smaller the ductile layer viscosity,the gentler the terrain change.This study further indicates that the weak lower crust plays an important role in the formation of geomorphic features and material migration characteristics of Qinghai-Tibet Plateau,and provides a new insight for the study of the uplift mechanism of the Tibetan Plateau.
文摘This research presents a Human Lower Limb Activity Recognition(HLLAR)system that identifies specific activities and predicts the angles of the knees simultaneously,based on the EMG signals.The HLLAR systems streamlines the research on the lower limb activities.The HILLAR model includes Discrete Hermite Wavelets Transform-based Synchrosqueezing(DHWTS),Deep Two-Layer Multiscale Convolutional Neural Network(DTLMCNN),and Generalized Regression Neural Network(GRNN)as feature extraction,activity recognition,and knee angle prediction respectively.Electromyography signal-based automatic lower limb activity detection is crucial to rehabilitation and human movement analysis.Yet several of these methods face issues in feature extraction in complex data,overlapping signals,extraction of crucial parameters,and adaptation constraints.This research aims classify lower limb activities and predict knee joint angles from electromy-ography signals using HILLAR model.The model is validated on two datasets,comprising 26 subjects performing three classes of activities:walking,standing,and sitting.The proposed model obtained a classification accuracy of 99.95%,along with significant achievements in precision(99.93%),recall(99.91%),and F1-score(99.93%).The generalized regression neural network predicted angles of the knee joint with a root mean squared error of 1.25%.Robustness is demonstrated through consistent results in five-fold cross-validation and statistical significance testing(p-value=0.004,McNemar's test).Additionally,the proposed model showed superior performance over baseline methods by reducing error rates by 18%and decreasing processing time to 0.98 s.
文摘Integration of renewable energy sources into power systems requires efficient multilevel inverters,capable of producing high-quality output voltage with low total harmonic distortion(THD).Conventional multilevel inverters often suffer from high component count,high switching stress,low voltage gain,and increased cost,limiting their practical application.This paper introduces a high-gain novel topology for multilevel inverters with reduced number of total components per level count,low voltage stress on power conductive devices,and minimizing a cost function,which depends on the number of components,standing voltage on switches and diodes,output voltage levels,and gain.The designed topology,which can be applied in photovoltaic(PV)systems,utilizes only one direct current(DC)input supply and a modular structure with the ability of capacitor’s voltage self-balancing.The high gain property and low THD of the proposed topology are two advantages that provide sine output waveform,with no need to a high DC input voltage source.Moreover,generalized topology,consisting of cascaded basic units,has been proposed.A comprehensive method has been proposed to determining the values of DC supplies in this configuration,aiming to minimize redundant switching modes and maximize the voltage levels count.The comparison with some other multilevel inverters confirms the desired performance of the basic version given inverter.A prototype has been also implemented and the experimental results have been obtained to verify the advantages of the proposed 25-level topology.
基金supported by the National Natural Science Foundation of China(62473337,62003305)the Key Research and Development Program of Zhejiang Province(2024C03040,2022C03029)the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang Province(2023R01006)。
文摘In this paper,a unified terminal sliding mode(UTSM)control method is proposed for second-order nonlinear systems with uncertainties and disturbances.It is seen that the newly defined terminal sliding surface is integrated with both conventional and fast terminal sliding mode and exhibits design advantages such as a variable exponent,adjustable sliding mode parameters,and chattering-alleviation effect.The inherent dynamic properties of the closed-loop systems with the UTSM control are discussed in detail via the phase plane and Lyapunov stability theory.Both numerical simulations and experimental results show the flexible sliding manifold design,strong robustness against uncertain dynamics,and effective attenuation of chattering phenomenon.
基金Harbin Municipal Bureau of Science and Technology Science and Technology Plan Self-funded Project(Grant/Award Number:2023ZCZJNS076)。
文摘Summary What''s New?:This study introduces a novel,periosteum-preserving iliac crest transverse transport(ICTT)technique for high-level lower extremity arteriosclerosis obliterans(LEASO),targeting patients unsuitable for conventional revascularization.Technical Innovation:By relocating the osteotomy from the weight-bearing tibia to the non-weight-bearing ilium,this minimally invasive technique eliminates the risk of stress fractures,allows for immediate full weight-bearing,and expands indications to patients with proximal arterial occlusions.
基金supported by the 1·3·5 project for disciplines of excellence-Clinical Research Incubation Project,West China Hospital,Sichuan University,China,No.2020HXFH051(to QG).
文摘Transcranial magnetic stimulation,a type of noninvasive brain stimulation,has become an ancillary therapy for motor function rehabilitation.Most previous studies have focused on the effects of repetitive transcranial magnetic stimulation(rTMS)on motor function in stroke patients.There have been relatively few studies on the effects of different modalities of rTMS on lower extremity motor function and corticospinal excitability in patients with stroke.The MEDLINE,Embase,Cochrane Library,ISI Science Citation Index,Physiotherapy Evidence Database,China National Knowledge Infrastructure Library,and ClinicalTrials.gov databases were searched.Parallel or crossover randomized controlled trials that addressed the effectiveness of rTMS in patients with stroke,published from inception to November 28,2019,were included.Standard pairwise meta-analysis was conducted using R version 3.6.1 with the“meta”package.Bayesian network analysis using the Markov chain Monte Carlo algorithm was conducted to investigate the effectiveness of different rTMS protocol interventions.Network meta-analysis results of 18 randomized controlled trials regarding lower extremity motor function recovery revealed that low-frequency rTMS had better efficacy in promoting lower extremity motor function recovery than sham stimulation.Network meta-analysis results of five randomized controlled trials demonstrated that highfrequency rTMS led to higher amplitudes of motor evoked potentials than low-frequency rTMS or sham stimulation.These findings suggest that rTMS can improve motor function in patients with stroke,and that low-frequency rTMS mainly affects motor function,whereas high-frequency rTMS increases the amplitudes of motor evoked potentials.More highquality randomized controlled trials are needed to validate this conclusion.The work was registered in PROSPERO(registration No.CRD42020147055)on April 28,2020.
文摘A new species of tapejarid pterosaur, Huaxiapterus coroUatus sp. nov. is erected on the basis of a nearly complete skull and postcranial skeleton from the Lower Cretaceous Jiufotang Formation of Liaoning Province, China. Huaxiapterus coroUatus sp. nov. is characterized by a hatchet-shaped rectangular process on the premaxilla, whose short axis is perpendicular to the anterior margin of the premaxillae. Except for this process, other characters of the skull such as the breadth of the snout between the anterior margin of the nasoantorbital fenestra and the anterior margin of the premaxilla are similar to that of Huaxiapterus jii. Huaxiapterus and a second Chinese tapejarid, Sinopterus, share several unique cranial characters in common with Tapejara and these three genera appear to be more closely related to each other than to other azhdarchoids. The Chinese tapejarids （Sinopterus and Huaxiapterus） have relatively elongate skulls and weakly developed cranial crests and seem to be less derived than Tapejara, with its shorter, deeper skull and large cranial crest. Tupuxuarids （Tupuxuara and Thalassodromeus） have often been associated with tapejarids in the family Tapejaridae, but this relationship is controversial because some phylogenetic analyses have supported the pairing of tupuxuarids with Azhdarchidae. We propose that Tapejaridae be restricted to Tapejara, Sinopterus and Huaxiapterus.
文摘BACKGROUNDDiabetes mellitus causes a large majority of non-traumatic major and minoramputations globally. Patients with diabetes are clinically complex with amultifactorial association between diabetic foot ulcers (DFU) and subsequentlower extremity amputations (LEA). Few studies show the long-term outcomeswithin the cohort of DFU-associated LEA.AIMTo highlight the long-term outcomes of LEA as a result of DFU.METHODSPubMed/MEDLINE and Google Scholar were searched for key terms, “diabetes”,“foot ulcers”, “amputations” and “outcomes”. Outcomes such as mortality, reamputation,re-ulceration and functional impact were recorded. Peer-reviewedstudies with adult patients who had DFU, subsequent amputation and follow upof at least 1 year were included. Non-English language articles or studiesinvolving children were excluded.RESULTSA total of 22 publications with a total of 2334 patients were selected against theinclusion criteria for review. The weighted mean of re-amputation was 20.14%,29.63% and 45.72% at 1, 3 and 5 years respectively. The weighted mean of mortality at 1, 3 and 5 years were 13.62%, 30.25% and 50.55% respectively withsignificantly higher rates associated with major amputation, re-amputation andischemic cardiomyopathy.CONCLUSIONPrevious LEA, level of the LEA and patient comorbidities were significant riskfactors contributing to re-ulceration, re-amputation, mortality and depreciatedfunctional status.
基金Projects(41506080,41702162)supported by the National Natural Science Foundation of ChinaProjects(DD20160152,DD20160147,GZH200800503)supported by China Geological Survey+1 种基金Projects(XQ-2005-01,2009GYXQ10)supported by China Ministry of Land and ResourcesProject(201602004)supported by the Postdoctoral Innovation Foundation of Shandong Province,China
文摘In the South Yellow Sea Basin,Mesozoic–Paleozoic marine strata are generally well developed with large thickness,and no substantial breakthroughs have been made in hydrocarbon exploration.Through research,it is believed that the Upper Permian–Lower Triassic can be regarded as a long-term base-level cycle.Based on drilling data,characteristics of the lithology–electric property combination cyclicity,and the special lithology,the long-term base-level cycle was divided into five medium-term base-level cycles(MC1–MC5).On this basis,the Permian–Triassic sedimentary systems and their filling model were analyzed in accordance with the change of base-level cycle and transition of sedimentary environment,as well as characteristics of the drilling sedimentary facies and seismic facies.The results show that there were six sedimentary systems(fluvial,delta,tidal flat,open platform,restricted platform,and continental shelf)developed in the Upper Permian–Lower Triassic,the sedimentary systems were distributed such that the water was deep in the northwest and shallow in the southeast,and there were two base-level cycle filling models(a relatively stable tidal flat facies and a rapidly transgressive continental shelf facies to stable platform facies)developed in the Upper Permian–Lower Triassic.These models can provide a basis for evaluation of the Mesozoic–Paleozoic hydrocarbon geology in the South Yellow Sea Basin.
基金Projects OF06142 supported by the National Basic Research Program of China2001CB209100 by the Science Foundation of China University of Mining and Technology
文摘The study area is located in the south of Huanxian county,in Yan'an and Puxian counties and to the north of Xi'an.The Shanxi and lower Shihezi formations are important gas-bearing formations.Given our analysis of the direction of rivers,the contents of stable heavy minerals and of feldspar of palaeo river systems,the study area is divided into six palaeodrainage patterns corresponding to six feldspar regions and six sedimentary facies regions.On this basis,the distribution of sedimentary facies was also analyzed.During the Shanxi stage,a delta front was deposited in the Huanxian region and delta plains and fronts were deposited in the Pingliang,Chunhua-Yaoxian and Hancheng-Chengcheng regions.In the Yan'an-Daning region,only a delta front was developed.The distribution of sedimentary facies in the earlier Shihezi stage originated from the Shanxi stage.A delta front was developed in the Huanxian region while a delta plain and front developed in the Pingliang-Zhenyuan region during the same time.Lakes originated only in the Zhenyuan-Huanxian-Huachi-Zhengning and Daning-Jixian zones.This analytical method shows that different palaeodrainage patterns can be effectively distinguished in order to forecast sedimentary facies.
基金the National Basic Research Program of China(Grant No.2016YFC0802700)the National Natural Science Foundation of China(Grant No.50975010,Grant No.51075017).
文摘Lower extremity robotic exoskeletons(LEEX)can not only improve the ability of the human body but also provide healing treatment for people with lower extremity dysfunction.There are a wide range of application needs and development prospects in the military,industry,medical treatment,consumption and other felds,which has aroused widespread concern in society.This paper attempts to review LEEX technical development.First,the history of LEEX is briefy traced.Second,based on existing research,LEEX is classifed according to auxiliary body parts,structural forms,functions and felds,and typical LEEX prototypes and products are introduced.Then,the latest key technologies are analyzed and summarized,and the research contents,such as bionic structure and driving characteristics,human–robot interaction(HRI)and intentawareness,intelligent control strategy,and evaluation method of power-assisted walking efciency,are described in detail.Finally,existing LEEX problems and challenges are analyzed,a future development trend is proposed,and a multidisciplinary development direction of the key technology is provided.
基金supported by the National Natural Science Foundation of China(No.61273129).
文摘The extended state observer(ESO)is the most important part of an emerging control technology known as active disturbance rejection control to this day,aiming at estimating"total disturbance"from observable measured output.In this paper,we construct a nonlinear ESO for a class of uncertain lower triangular nonlinear systems with stochastic disturbance and show its convergence,where the total disturbance includes internal uncertain nonlinear part and external stochastic disturbance.The numerical experiments are carried out to illustrate effectiveness of the proposed approach.
文摘BACKGROUND Prostate artery embolization(PAE)is a promising minimally invasive therapy that improves lower urinary tract symptoms(LUTS)related to benign prostatic hyperplasia(BPH).Transurethral resection of the prostate(TURP)is the gold standard therapy for LUTS/BPH.AIM To evaluate the efficacy and safety of PAE vs TURP on LUTS related to BPH.METHODS A literature review was performed to identify all published articles on PAE vs TURP for LUTS/BPH.Sources included PubMed,Embase,Cochrane library databases,and Chinese databases before June 2022.A systematic review and meta-analysis were conducted.Outcome measurements were combined by calculating the mean difference with a 95%confidence interval.Statistical analysis was carried out using Review Manager 5.3.RESULTS Eleven studies involving 1070 participants were included.Compared with the TURP group,the PAE group had a similar effect on the International Index of Erectile Function(IPSS)score,Peak urinary flow rate(Qmax),postvoid residual volume(PVR),Prostate volume(PV),prostatic specific antigen(PSA),The International Index of Erectile Function short form(IIEF-5)scores,and erectile dysfunction during 24 mo follow-up.Lower quality of life(QoL)score,lower rate of retrograde ejaculation and shorter hospital stay in the PAE group.There was no participant death in either group.A higher proportion of haematuria,urinary incontinence and urinary stricture was identified in the TURP group.CONCLUSION PAE may be an appropriate option for elderly patients,patients who are not candidates for surgery,and patients who do not want to risk the potential adverse effects of TURP.Studies with large cases and long follow-up time are needed to validate results.
文摘Li et al. in [3] obtained blow-up results for a system of Petrovskey equations in some different cases. In this article we obtain lower bounds for the blow up time under some considerations on initial data.
