In order to simulate the real growing process, a new type of knowledge network growth mechanism based on local world connectivity is constructed. By the mean-field method, theoretical prediction of the degree distribu...In order to simulate the real growing process, a new type of knowledge network growth mechanism based on local world connectivity is constructed. By the mean-field method, theoretical prediction of the degree distribution of the knowledge network is given, which is verified by Matlab simulations. When the new added node's local world size is very small, the degree distribution of the knowledge network approximately has the property of scale-free. When the new added node's local world size is not very small, the degree distribution transforms from pure power-law to the power-law with an exponential tailing. And the scale-free index increases as the number of new added edges decreases and the tunable parameters increase. Finally, comparisons of some knowledge indices in knowledge networks generated by the local world mechanism and the global mechanism are given. In the long run, compared with the global mechanism, the local world mechanism leads the average knowledge levels to slower growth and brings homogenous phenomena.展开更多
Background: Localized pancreatic cancer, including resectable (R), borderline resectable (BR) and locally advanced unresectable disease (LAU), is considered in clinical guidelines for diverse treatment options based o...Background: Localized pancreatic cancer, including resectable (R), borderline resectable (BR) and locally advanced unresectable disease (LAU), is considered in clinical guidelines for diverse treatment options based on clinical trials in selected populations. Hence, exploring with real world evidence (RWE) clinicians’ preferences for treatment options and their results seems pertinent. Methods: In a set of consecutive patients with localized pancreatic cancer assisted in a third level hospital from January 2013 to December 2022, medical records, symptoms, diagnostic process, distribution between subtypes, and treatment plans, with safety and efficacy results, were assessed. Results: A total of 152 patients with localized disease were included (43.4% R, 21.0% BR, 33.6% LAU). The population characteristics exemplified differences between daily practice and clinical trials. Tumor location and symptoms were as expected. Treatment plan was conditioned by PS or comorbidities in 23.0% of patients. In patients with R disease, surgery followed by different adjuvant chemotherapy (CT) regimes was the antineoplastic treatment of choice (64.8%) with efficacy results (OS 37.5 months;95% CI 18.4 - 56.7), in the range of contemporary standards. The common use of neoadjuvant CT for BR disease (94.4%), with surgery in 50% of them, and its results (OS 30.8 months;95% CI 10.5 - 51.2) reflected current controversies of treatment recommendations and evolution in this scenario. Paliative CT with or without radiotherapy was the standard specific treatment in LAU disease (95.1%) with survival results (PFS: 10.8 months;95% CI 8.8 - 12.7. OS: 20.3 months;95% CI 13.5 - 27.2) that justify the distinct character and the specific study of this entity. Conclusion: RWE for localized pancreatic cancer aroused from the analysis of this population confirms the distinct nature of patients assisted in daily practice, as well as mirrors the complexity of decision making in clinical assumptions in which achieving stronger evidence should be paramount.展开更多
The local-world (LW) evolving network model shows a transition for the degree distribution between the exponential and power-law distributions, depending on the LW size. Cascading failures under intentional attacks in...The local-world (LW) evolving network model shows a transition for the degree distribution between the exponential and power-law distributions, depending on the LW size. Cascading failures under intentional attacks in LW network models with different LW sizes were investigated using the cascading failures load model. We found that the LW size has a significant impact on the network's robustness against deliberate attacks. It is much easier to trigger cascading failures in LW evolving networks with a larger LW size. Therefore, to avoid cascading failures in real networks with local preferential attachment such as the Internet, the World Trade Web and the multi-agent system, the LW size should be as small as possible.展开更多
This article theorises the local world as a conceptual scaffold for future conservation and regeneration.It aims to catalyse a theoretical dialogue across the East and West to understand how ordinary places and lifewo...This article theorises the local world as a conceptual scaffold for future conservation and regeneration.It aims to catalyse a theoretical dialogue across the East and West to understand how ordinary places and lifeworlds are preserved,reproduced,and possibly reimagined.The local worlds discussed herein are conceptualised as the worlds of many,the worlds of relating,the worlds of structuring and the worlds of becoming.These four cardinal points present a source of open-endedness and futurity for contemporary architectural reinterpretation.The current article examines the characterisation of the Wen village conservation and regeneration project,led by the Amateur Architecture Studio in Zhejiang Province of China(2012–2016),as an architectural reimagination of local worlds,with a strong sensitivity to the ordinary places and lifeworlds of rural China and juxtapositions of new local worlds within old worlds.By piecing together the flows and fragments of the architectural process,this article shows how locally situated designs and dynamics have shaped the project in both its formation and afterlife,both ethically and contemporarily.Using close readings of popular and oral accounts from both architect’s and users’perspectives,this article extends the case study by broadening theoretical conversations about contemporary architecture’s capacity to reimagine local worlds.展开更多
In some real complex networks, only a few nodes can obtain the global information about the entire networks, but most of the nodes own only local connections therefore own only local information of the networks. A new...In some real complex networks, only a few nodes can obtain the global information about the entire networks, but most of the nodes own only local connections therefore own only local information of the networks. A new local-world evolving network model is proposed in this paper. In the model, not all the nodes obtain local network information, which is different from the local world network model proposed by Li and Chen (LC model). In the LC model, each node has only the local connections therefore owns only local information about the entire networks. Theoretical analysis and numerical simulation show that adjusting the ratio of the number of nodes obtaining the global information of the network to the total number of nodes can effectively control the valuing range for the power-law exponent of the new network. Therefore, if the topological structure of a complex network, especially its exponent of power-law degree distribution, needs controlling, we just add or take away a few nodes which own the global information of the network.展开更多
In the propagation of an epidemic in a population, individuals adaptively adjust their behavior to avoid the risk of an epidemic. Differently from existing studies where new links are established randomly, a local lin...In the propagation of an epidemic in a population, individuals adaptively adjust their behavior to avoid the risk of an epidemic. Differently from existing studies where new links are established randomly, a local link is established preferentially in this paper. We propose a new preferentially reconnecting edge strategy depending on spatial distance (PR- SD). For the PR-SD strategy, the new link is established at random with probability p and in a shortest distance with the probability 1 p. We establish the epidemic model on an adaptive network using Cellular Automata, and demonstrate the effectiveness of the proposed model by numerical simulations. The results show that the smaller the value of parameter p, the more difficult the epidemic spread is. The PR-SD strategy breaks long-range links and establishes as many short-range links as possible, which causes the network efficiency to decrease quickly and the propagation of the epidemic is restrained effectively.展开更多
Complex hypernetworks are ubiquitous in the real system. It is very important to investigate the evolution mecha- nisms. In this paper, we present a local-world evolving hypernetwork model by taking into account the h...Complex hypernetworks are ubiquitous in the real system. It is very important to investigate the evolution mecha- nisms. In this paper, we present a local-world evolving hypernetwork model by taking into account the hyperedge growth and local-world hyperedge preferential attachment mechanisms. At each time step, a newly added hyperedge encircles a new coming node and a number of nodes from a randomly selected local world. The number of the selected nodes from the local world obeys the uniform distribution and its mean value is m. The analytical and simulation results show that the hyperdegree approximately obeys the power-law form and the exponent of hyperdegree distribution is 7 = 2 + 1/m. Furthermore, we numerically investigate the node degree, hyperedge degree, clustering coefficient, as well as the average distance, and find that the hypemetwork model shares the scale-flee and small-world properties, which shed some light for deeply understanding the evolution mechanism of the real systems.展开更多
近年来,国家多项政策助力我国科技期刊迅速发展。加快培育世界一流科技期刊和促进“双回流”是现阶段2大核心任务。本文以中国内地第一本英文体育学术期刊《Journal of Sport and Health Science》[《JSHS》,《运动与健康科学》(英文)]...近年来,国家多项政策助力我国科技期刊迅速发展。加快培育世界一流科技期刊和促进“双回流”是现阶段2大核心任务。本文以中国内地第一本英文体育学术期刊《Journal of Sport and Health Science》[《JSHS》,《运动与健康科学》(英文)]为例,围绕国际化和本土化,从刊文内容国际化、办刊队伍国际化、学术传播国际化和本土化服务国家战略、培育中国作者、助力学术交流与学科建设、稳步推进“双回流”建设等方面进行阐述,基于关键数据及特色案例,介绍《JSHS》“面向世界,立足本土”的办刊实践。展开更多
为提高ORB-SLAM2 (oriented fast and rotated brief, and simultaneous localization and mapping)系统的位姿估计精度并解决仅能生成稀疏地图的问题,提出了融合迭代最近点拟合(iterative closest point, ICP)算法与曼哈顿世界假说的...为提高ORB-SLAM2 (oriented fast and rotated brief, and simultaneous localization and mapping)系统的位姿估计精度并解决仅能生成稀疏地图的问题,提出了融合迭代最近点拟合(iterative closest point, ICP)算法与曼哈顿世界假说的位姿估计策略并在系统中加入稠密建图线程。首先通过ORB(oriented fast and rotated brief)特征点法、最小显著性差异(least-significant difference, LSD)算法和聚集层次聚类(agglomerative hierarchical clustering, AHC)方法提取点、线、面特征,其中点、线特征与上一帧匹配,面特征在全局地图匹配。然后采用基于surfel的稠密建图策略将图像划分为非平面与平面区域,非平面采用ICP算法计算位姿,平面则通过面与面的正交关系确定曼哈顿世界从而使用不同估计策略,其中曼哈顿世界场景通过位姿解耦实现基于曼哈顿帧观测的无漂移旋转估计,而该场景的平移以及非曼哈顿世界场景的位姿采用追踪的点、线、面特征进行估计和优化;最后根据关键帧和相应位姿实现稠密建图。采用慕尼黑工业大学(technische universit?t münchen, TUM)数据集验证所提建图方法,经过与ORB-SLAM2算法比较,均方根误差平均减少0.24 cm,平均定位精度提高7.17%,验证了所提方法进行稠密建图的可行性和有效性。展开更多
基金The National Natural Science Foundation of China(No70571013,70973017)Program for New Century Excellent Talentsin University (NoNCET-06-0471)Human Social Science Fund Project ofMinistry of Education (No09YJA630020)
文摘In order to simulate the real growing process, a new type of knowledge network growth mechanism based on local world connectivity is constructed. By the mean-field method, theoretical prediction of the degree distribution of the knowledge network is given, which is verified by Matlab simulations. When the new added node's local world size is very small, the degree distribution of the knowledge network approximately has the property of scale-free. When the new added node's local world size is not very small, the degree distribution transforms from pure power-law to the power-law with an exponential tailing. And the scale-free index increases as the number of new added edges decreases and the tunable parameters increase. Finally, comparisons of some knowledge indices in knowledge networks generated by the local world mechanism and the global mechanism are given. In the long run, compared with the global mechanism, the local world mechanism leads the average knowledge levels to slower growth and brings homogenous phenomena.
文摘Background: Localized pancreatic cancer, including resectable (R), borderline resectable (BR) and locally advanced unresectable disease (LAU), is considered in clinical guidelines for diverse treatment options based on clinical trials in selected populations. Hence, exploring with real world evidence (RWE) clinicians’ preferences for treatment options and their results seems pertinent. Methods: In a set of consecutive patients with localized pancreatic cancer assisted in a third level hospital from January 2013 to December 2022, medical records, symptoms, diagnostic process, distribution between subtypes, and treatment plans, with safety and efficacy results, were assessed. Results: A total of 152 patients with localized disease were included (43.4% R, 21.0% BR, 33.6% LAU). The population characteristics exemplified differences between daily practice and clinical trials. Tumor location and symptoms were as expected. Treatment plan was conditioned by PS or comorbidities in 23.0% of patients. In patients with R disease, surgery followed by different adjuvant chemotherapy (CT) regimes was the antineoplastic treatment of choice (64.8%) with efficacy results (OS 37.5 months;95% CI 18.4 - 56.7), in the range of contemporary standards. The common use of neoadjuvant CT for BR disease (94.4%), with surgery in 50% of them, and its results (OS 30.8 months;95% CI 10.5 - 51.2) reflected current controversies of treatment recommendations and evolution in this scenario. Paliative CT with or without radiotherapy was the standard specific treatment in LAU disease (95.1%) with survival results (PFS: 10.8 months;95% CI 8.8 - 12.7. OS: 20.3 months;95% CI 13.5 - 27.2) that justify the distinct character and the specific study of this entity. Conclusion: RWE for localized pancreatic cancer aroused from the analysis of this population confirms the distinct nature of patients assisted in daily practice, as well as mirrors the complexity of decision making in clinical assumptions in which achieving stronger evidence should be paramount.
基金the National Basic Research Program (973) of China (No. 2004CB217902)the National Natural Science Foundation of China (Nos. 60421002 and 60804045)the Postdoctoral Science Foundation of China (No. 20070421163)
文摘The local-world (LW) evolving network model shows a transition for the degree distribution between the exponential and power-law distributions, depending on the LW size. Cascading failures under intentional attacks in LW network models with different LW sizes were investigated using the cascading failures load model. We found that the LW size has a significant impact on the network's robustness against deliberate attacks. It is much easier to trigger cascading failures in LW evolving networks with a larger LW size. Therefore, to avoid cascading failures in real networks with local preferential attachment such as the Internet, the World Trade Web and the multi-agent system, the LW size should be as small as possible.
基金supported by the University of Sheffield School of Architecture research funding.
文摘This article theorises the local world as a conceptual scaffold for future conservation and regeneration.It aims to catalyse a theoretical dialogue across the East and West to understand how ordinary places and lifeworlds are preserved,reproduced,and possibly reimagined.The local worlds discussed herein are conceptualised as the worlds of many,the worlds of relating,the worlds of structuring and the worlds of becoming.These four cardinal points present a source of open-endedness and futurity for contemporary architectural reinterpretation.The current article examines the characterisation of the Wen village conservation and regeneration project,led by the Amateur Architecture Studio in Zhejiang Province of China(2012–2016),as an architectural reimagination of local worlds,with a strong sensitivity to the ordinary places and lifeworlds of rural China and juxtapositions of new local worlds within old worlds.By piecing together the flows and fragments of the architectural process,this article shows how locally situated designs and dynamics have shaped the project in both its formation and afterlife,both ethically and contemporarily.Using close readings of popular and oral accounts from both architect’s and users’perspectives,this article extends the case study by broadening theoretical conversations about contemporary architecture’s capacity to reimagine local worlds.
基金supported by the Scientific Research Starting Foundation of Hangzhou Dianzi University (Grant No KYS091507073)partly by the National High Technology Research and Development Program of China (Grant No 2005AA147030)
文摘In some real complex networks, only a few nodes can obtain the global information about the entire networks, but most of the nodes own only local connections therefore own only local information of the networks. A new local-world evolving network model is proposed in this paper. In the model, not all the nodes obtain local network information, which is different from the local world network model proposed by Li and Chen (LC model). In the LC model, each node has only the local connections therefore owns only local information about the entire networks. Theoretical analysis and numerical simulation show that adjusting the ratio of the number of nodes obtaining the global information of the network to the total number of nodes can effectively control the valuing range for the power-law exponent of the new network. Therefore, if the topological structure of a complex network, especially its exponent of power-law degree distribution, needs controlling, we just add or take away a few nodes which own the global information of the network.
基金Project supported by the Natural Science Foundation of Jiangsu Province, China (Grant No. BK2010526)the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20103223110003)the Ministry of Education Research in the Humanities and Social Sciences Planning Fund (Grant No. 12YJAZH120)
文摘In the propagation of an epidemic in a population, individuals adaptively adjust their behavior to avoid the risk of an epidemic. Differently from existing studies where new links are established randomly, a local link is established preferentially in this paper. We propose a new preferentially reconnecting edge strategy depending on spatial distance (PR- SD). For the PR-SD strategy, the new link is established at random with probability p and in a shortest distance with the probability 1 p. We establish the epidemic model on an adaptive network using Cellular Automata, and demonstrate the effectiveness of the proposed model by numerical simulations. The results show that the smaller the value of parameter p, the more difficult the epidemic spread is. The PR-SD strategy breaks long-range links and establishes as many short-range links as possible, which causes the network efficiency to decrease quickly and the propagation of the epidemic is restrained effectively.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.71071098,91024026,and 71171136)supported by the Shanghai Rising-Star Program,China(Grant No.11QA1404500)the Leading Academic Discipline Project of Shanghai City,China(Grant No.XTKX2012)
文摘Complex hypernetworks are ubiquitous in the real system. It is very important to investigate the evolution mecha- nisms. In this paper, we present a local-world evolving hypernetwork model by taking into account the hyperedge growth and local-world hyperedge preferential attachment mechanisms. At each time step, a newly added hyperedge encircles a new coming node and a number of nodes from a randomly selected local world. The number of the selected nodes from the local world obeys the uniform distribution and its mean value is m. The analytical and simulation results show that the hyperdegree approximately obeys the power-law form and the exponent of hyperdegree distribution is 7 = 2 + 1/m. Furthermore, we numerically investigate the node degree, hyperedge degree, clustering coefficient, as well as the average distance, and find that the hypemetwork model shares the scale-flee and small-world properties, which shed some light for deeply understanding the evolution mechanism of the real systems.
文摘近年来,国家多项政策助力我国科技期刊迅速发展。加快培育世界一流科技期刊和促进“双回流”是现阶段2大核心任务。本文以中国内地第一本英文体育学术期刊《Journal of Sport and Health Science》[《JSHS》,《运动与健康科学》(英文)]为例,围绕国际化和本土化,从刊文内容国际化、办刊队伍国际化、学术传播国际化和本土化服务国家战略、培育中国作者、助力学术交流与学科建设、稳步推进“双回流”建设等方面进行阐述,基于关键数据及特色案例,介绍《JSHS》“面向世界,立足本土”的办刊实践。
文摘为提高ORB-SLAM2 (oriented fast and rotated brief, and simultaneous localization and mapping)系统的位姿估计精度并解决仅能生成稀疏地图的问题,提出了融合迭代最近点拟合(iterative closest point, ICP)算法与曼哈顿世界假说的位姿估计策略并在系统中加入稠密建图线程。首先通过ORB(oriented fast and rotated brief)特征点法、最小显著性差异(least-significant difference, LSD)算法和聚集层次聚类(agglomerative hierarchical clustering, AHC)方法提取点、线、面特征,其中点、线特征与上一帧匹配,面特征在全局地图匹配。然后采用基于surfel的稠密建图策略将图像划分为非平面与平面区域,非平面采用ICP算法计算位姿,平面则通过面与面的正交关系确定曼哈顿世界从而使用不同估计策略,其中曼哈顿世界场景通过位姿解耦实现基于曼哈顿帧观测的无漂移旋转估计,而该场景的平移以及非曼哈顿世界场景的位姿采用追踪的点、线、面特征进行估计和优化;最后根据关键帧和相应位姿实现稠密建图。采用慕尼黑工业大学(technische universit?t münchen, TUM)数据集验证所提建图方法,经过与ORB-SLAM2算法比较,均方根误差平均减少0.24 cm,平均定位精度提高7.17%,验证了所提方法进行稠密建图的可行性和有效性。